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Author : Xueqing Gong
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (117 download)
Download or read book Insight Into Reactions on Solid Surfaces and in Proteins written by Xueqing Gong and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ajit Sadana
Publisher : Elsevier
ISBN 13 : 0080528147
Total Pages : 367 pages
Book Rating : 4.0/5 (85 download)
Download or read book Bioseparations of Proteins written by Ajit Sadana and published by Elsevier. This book was released on 1997-11-27 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the fundamentals of protein inactivation during bioseparation and the effect on protein processing. Bioseparation of Proteins is unique because it provides a background of the bioseparation processes, and it is the first book available to emphasize the influence of the different bioseparation processes on protein inactivation. Bioseparation of Proteins covers the extent, mechanisms of, and control of protein inactivation during these processes along with the subsequent and essential validation of these processes. The book focuses on the avoidance of protein (biologicalproduct) inactivation at each step in a bioprocess. It compares protein inactivation exhibited during the different bioseparation processes by different workers and provides a valuable framework for workers in different areas interested in bioseparations. Topics include separation and detection methods; estimates of protein inactivation and an analysis of this problem for different separation processes; strategies for avoiding inactivation; the molecular basis of surface activity and protein adsorption,process monitoring, and product validation techniques; and the economics of various bioseparation processes and quality control procedures. Key Features * Protein inactivation and other aspects of biological stability are critical to an effective bioseparation process; This book is a detailed and critical review of the available literature in an area that is essential to the effectiveness, validation, and economics of bioseparation processes for drugs and other biological products; Conveniently assembled under one cover, the survey of the literature and resulting perspective will greatly assist engineers and chemists in designingand improving their own processes; Key features of the text include: * detailed data on biological stability under various bioseparation conditions * extensive case studies from the literature on separation processes, validation, and economics * simplified analysis of protein refolding and inactivation mechanisms * consideration of adsorption theories and the effect of heterogeneity * coverage of both classical and novel bioseparation techniques, including chromatographic procedures
Author : Gerhard Ertl
Publisher : John Wiley & Sons
ISBN 13 : 0470261013
Total Pages : 237 pages
Book Rating : 4.4/5 (72 download)
Download or read book Reactions at Solid Surfaces written by Gerhard Ertl and published by John Wiley & Sons. This book was released on 2009-10-26 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the ideas first presented in Gerhard Ertl's acclaimed Baker Lectures at Cornell University, Reactions at Solid Surfaces comprises an authoritative, self-contained, book-length introduction to surface reactions for both professional chemists and students alike. Outlining our present understanding of the fundamental processes underlying reactions at solid surfaces, the book provides the reader with a complete view of how chemistry works at surfaces, and how to understand and probe the dynamics of surface reactions. Comparing traditional surface probes with more modern ones, and bringing together various disciplines in a cohesive manner, Gerhard Ertl's Reactions at Solid Surfaces serves well as a primary text for graduate students in introductory surface science or chemistry, as well as a self-teaching resource for professionals in surface science, chemical engineering, or nanoscience.
Author : Mark A. Williams
Publisher : Humana
ISBN 13 : 9781493958733
Total Pages : 0 pages
Book Rating : 4.9/5 (587 download)
Download or read book Protein-Ligand Interactions written by Mark A. Williams and published by Humana. This book was released on 2016-11-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins are the cell’s workers, their messengers and overseers. In these roles, proteins specifically bind small molecules, nucleic acid and other protein partners. Cellular systems are closely regulated and biologically significant changes in populations of particular protein complexes correspond to very small variations of their thermodynamics or kinetics of reaction. Interfering with the interactions of proteins is the dominant strategy in the development of new pharmaceuticals. Protein Ligand Interactions: Methods and Applications, Second Edition provides a complete introduction to common and emerging procedures for characterizing the interactions of individual proteins. From the initial discovery of natural substrates or potential drug leads, to the detailed quantitative understanding of the mechanism of interaction, all stages of the research process are covered with a focus on those techniques that are, or are anticipated to become, widely accessible and performable with mainstream commercial instrumentation. Written in the highly successful Methods in Molecular Biology series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Protein Ligand Interactions: Methods and Applications, Second Edition serves as an ideal guide for researchers new to the field of biophysical characterization of protein interactions – whether they are beginning graduate students or experts in allied areas of molecular cell biology, microbiology, pharmacology, medicinal chemistry or structural biology.
Author : Michael C. Flickinger
Publisher : John Wiley & Sons
ISBN 13 : 1118619277
Total Pages : 3600 pages
Book Rating : 4.1/5 (186 download)
Download or read book Upstream Industrial Biotechnology, 2 Volume Set written by Michael C. Flickinger and published by John Wiley & Sons. This book was released on 2013-07-22 with total page 3600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology represents a major area of research focus, and many universities are developing academic programs in the field. This guide to biomanufacturing contains carefully selected articles from Wiley's Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell Technology as well as new articles (80 in all,) and features the same breadth and quality of coverage and clarity of presentation found in the original. For instructors, advanced students, and those involved in regulatory compliance, this two-volume desk reference offers an accessible and comprehensive resource.
Author : Virulh Sa-yakanit
Publisher : World Scientific
ISBN 13 : 9789812811301
Total Pages : 366 pages
Book Rating : 4.8/5 (113 download)
Download or read book Proceedings of the First Workshop on Biological Physics 2000 written by Virulh Sa-yakanit and published by World Scientific. This book was released on 2001 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to the broad subject of flavor physics, embracing the question of what distinguishes one type of elementary particles from another. The articles range from the forefront of formal theory (treating the physics of extra dimensions) to details of particle detectors. Although special emphasis is placed on the physics of kaons, charmed and beauty particles, top quarks, and neutrinos, the articles also dealing with electroweak physics, quantum chromodynamics, supersymmetry, and dynamical electroweak symmetry breaking. Violations of fundamental symmetries such as time reversal invariance are discussed in the context of neutral kaons, beauty particles, electric dipole moments, and parity violation in atoms. The physics of the Cabibbo-Kobayashi-Maskawa matrix and of quark masses are described in some detail, both from the standpoint of present and future experimental knowledge and from a more fundamental viewpoint, where physicists are still searching for the correct theory
Author : Alexander E. Knight
Publisher : Academic Press
ISBN 13 : 008092123X
Total Pages : 369 pages
Book Rating : 4.0/5 (89 download)
Download or read book Single Molecule Biology written by Alexander E. Knight and published by Academic Press. This book was released on 2009-02-26 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single molecule techniques, including single molecule fluorescence, optical tweezers, and scanning probe microscopy, allow for the manipulation and measurement of single biological molecules within a live cell or in culture. These approaches, amongst the most exciting tools available in biology today, offer powerful new ways to elucidate biological function, both in terms of revealing mechanisms of action on a molecular level as well as tracking the behaviour of molecules in living cells. This book provides the first complete and authoritative treatment of this rapidly emerging field, explicitly from a biological perspective.The contents are organized by biological system or molecule. Each chapter discusses insights that have been revealed about their mechanism, structure or function by single molecule techniques. Among the topics covered are enzymes, motor proteins, membrane channels, DNA, ribozymes, cytoskeletal proteins, and other key molecules of current interest. An introduction by the editor provides a concise review of key principles and an historical overview. The last section discusses applications in molecular diagnostics and drug discovery. Organized by biological system or molecule Each chapter discusses insights into mechanism of action, structure, and function Covers enzymes, motor proteins, membrane channels, DNA, ribozymes, etc Includes an introduction to key principles and an historical overview Discusses applications in molecular diagnostics and drug discovery Provides an expert's perspective on future development
Author : Daniel Rabinovich
Publisher : Springer
ISBN 13 : 3662435993
Total Pages : 159 pages
Book Rating : 4.6/5 (624 download)
Download or read book Molecular Design in Inorganic Biochemistry written by Daniel Rabinovich and published by Springer. This book was released on 2014-07-01 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical structure and bonding. The scope of the series spans the entire Periodic Table and addresses structure and bonding issues associated with all of the elements. It also focuses attention on new and developing areas of modern structural and theoretical chemistry such as nanostructures, molecular electronics, designed molecular solids, surfaces, metal clusters and supramolecular structures. Physical and spectroscopic techniques used to determine, examine and model structures fall within the purview of Structure and Bonding to the extent that the focus is on the scientific results obtained and not on specialist information concerning the techniques themselves. Issues associated with the development of bonding models and generalizations that illuminate the reactivity pathways and rates of chemical processes are also relevant. The individual volumes in the series are thematic. The goal of each volume is to give the reader, whether at a university or in industry, a comprehensive overview of an area where new insights are emerging that are of interest to a larger scientific audience. Thus each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years should be presented using selected examples to illustrate the principles discussed. A description of the physical basis of the experimental techniques that have been used to provide the primary data may also be appropriate, if it has not been covered in detail elsewhere. The coverage need not be exhaustive in data, but should rather be conceptual, concentrating on the new principles being developed that will allow the reader, who is not a specialist in the area covered, to understand the data presented. Discussion of possible future research directions in the area is welcomed. Review articles for the individual volumes are invited by the volume editors.
Author : Izet Kapetanović
Publisher : BoD – Books on Demand
ISBN 13 : 9533076151
Total Pages : 544 pages
Book Rating : 4.5/5 (33 download)
Download or read book Drug Discovery and Development written by Izet Kapetanović and published by BoD – Books on Demand. This book was released on 2011-12-16 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug discovery and development process aims to make available medications that are safe and effective in improving the length and quality of life and relieving pain and suffering. However, the process is very complex, time consuming, resource intensive, requiring multi-disciplinary expertise and innovative approaches. There is a growing urgency to identify and develop more effective, efficient, and expedient ways to bring safe and effective products to the market. The drug discovery and development process relies on the utilization of relevant and robust tools, methods, models, and validated biomarkers that are predictive of clinical effects in terms of diagnosis, prevention, therapy, and prognosis. There is a growing emphasis on translational research, a bidirectional bench to the bedside approach, in an effort to improve the process efficiency and the need for further innovations. The authors in the book discuss the current and evolving state of drug discovery and development.
Author : Barbara Detrick
Publisher : John Wiley & Sons
ISBN 13 : 1555818722
Total Pages : 1240 pages
Book Rating : 4.5/5 (558 download)
Download or read book Manual of Molecular and Clinical Laboratory Immunology written by Barbara Detrick and published by John Wiley & Sons. This book was released on 2020-07-16 with total page 1240 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE authoritative guide for clinical laboratory immunology For over 40 years the Manual of Molecular and Clinical Laboratory Immunology has served as the premier guide for the clinical immunology laboratory. From basic serology testing to the present wide range of molecular analyses, the Manual has reflected the exponential growth in the field of immunology over the past decades. This eighth edition reflects the latest advances and developments in the diagnosis and treatment of patients with infectious and immune-mediated disorders. The Manual features detailed descriptions of general and specific methodologies, placing special focus on the interpretation of laboratory findings, and covers the immunology of infectious diseases, including specific pathogens, as well as the full range of autoimmune and immunodeficiency diseases, cancer, and transplantation. Written to guide the laboratory director, the Manual will also appeal to other laboratory scientists, especially those working in clinical immunology laboratories, and pathologists. It is also a useful reference for physicians, mid-level providers, medical students, and allied health students with an interest in the role that immunology plays in the clinical laboratory.
Author : Ajit Sadana
Publisher : Elsevier
ISBN 13 : 9780444515124
Total Pages : 426 pages
Book Rating : 4.5/5 (151 download)
Download or read book Biosensors: Kinetics of Binding and Dissociation Using Fractals written by Ajit Sadana and published by Elsevier. This book was released on 2003-12-17 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Effect of Reynolds number on fractal binding kinetics on a surface-based biosensor -- DNA fractal binding and dissociation kinetics -- Fractal analysis of binding and dissociation interactions of estrogen receptors to ligands on biosensor surfaces -- A fractal analysis of analyte-estrogen receptor binding and dissociation kinetics using biosensors : environmental effects -- A fractal analysis of analyte-estrogen receptor binding and dissociation kinetics using biosensors : biomedical effects -- Fractal analysis of binding interactions of nuclear estrogen receptors occurring on biosensor surfaces -- A kinetic study of analyte-receptor binding and dissociation for biosensor applications : a fractal analysis for cholera toxin and peptide-protein interactions / -- The temporal nature of the binding and dissociation rate coefficients and the affinity values for biosensor kinetics -- Fractal analysis of analyte-receptor binding and dissociation, and dissociation alone for biosensor applicati ...
Author : Buddy D. Ratner
Publisher : Academic Press
ISBN 13 : 008087780X
Total Pages : 1573 pages
Book Rating : 4.0/5 (88 download)
Download or read book Biomaterials Science written by Buddy D. Ratner and published by Academic Press. This book was released on 2012-12-31 with total page 1573 pages. Available in PDF, EPUB and Kindle. Book excerpt: The revised edition of this renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science. It provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. Over 29,000 copies sold, this is the most comprehensive coverage of principles and applications of all classes of biomaterials: "the only such text that currently covers this area comprehensively" - Materials Today Edited by four of the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and expanded, key new topics include of tissue engineering, drug delivery systems, and new clinical applications, with new teaching and learning material throughout, case studies and a downloadable image bank
Author : Isabel Moraes
Publisher : Springer
ISBN 13 : 3319350722
Total Pages : 188 pages
Book Rating : 4.3/5 (193 download)
Download or read book The Next Generation in Membrane Protein Structure Determination written by Isabel Moraes and published by Springer. This book was released on 2016-08-23 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews current techniques used in membrane protein structural biology, with a strong focus on practical issues. The study of membrane protein structures not only provides a basic understanding of life at the molecular level but also helps in the rational and targeted design of new drugs with reduced side effects. Today, about 60% of the commercially available drugs target membrane proteins and it is estimated that nearly 30% of proteins encoded in the human genome are membrane proteins. In recent years much effort has been put towards innovative developments to overcome the numerous obstacles associated with the structure determination of membrane proteins. This book reviews a variety of recent techniques that are essential to any modern researcher in the field of membrane protein structural biology. The topics that are discussed are not commonly found in textbooks. The scope of this book includes: Expression screening using fluorescent proteins The use of detergents in membrane protein research The use of NMR Synchrotron developments in membrane protein structural biology Visualisation and X-ray data collection of microcrystals X-ray diffraction data analysis from multiple crystals Serial millisecond crystallography Serial femtosecond crystallography Membrane protein structures in drug discovery The information provided in this book should be of interest to anyone working in the area of structural biology. Students will find carefully prepared overviews of basic ideas and advanced protein scientists will find the level of detail required to apply the material directly to their day to day work. Chapters 4, 5, 6, 8 and 9 of this book are published open access under a CC BY 4.0 license at link.springer.com.
Author :
Publisher : Academic Press
ISBN 13 : 0128032251
Total Pages : 3716 pages
Book Rating : 4.1/5 (28 download)
Download or read book Encyclopedia of Spectroscopy and Spectrometry written by and published by Academic Press. This book was released on 2016-09-22 with total page 3716 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition of the Encyclopedia of Spectroscopy and Spectrometry, Three Volume Set provides authoritative and comprehensive coverage of all aspects of spectroscopy and closely related subjects that use the same fundamental principles, including mass spectrometry, imaging techniques and applications. It includes the history, theoretical background, details of instrumentation and technology, and current applications of the key areas of spectroscopy. The new edition will include over 80 new articles across the field. These will complement those from the previous edition, which have been brought up-to-date to reflect the latest trends in the field. Coverage in the third edition includes: Atomic spectroscopy Electronic spectroscopy Fundamentals in spectroscopy High-Energy spectroscopy Magnetic resonance Mass spectrometry Spatially-resolved spectroscopic analysis Vibrational, rotational and Raman spectroscopies The new edition is aimed at professional scientists seeking to familiarize themselves with particular topics quickly and easily. This major reference work continues to be clear and accessible and focus on the fundamental principles, techniques and applications of spectroscopy and spectrometry. Incorporates more than 150 color figures, 5,000 references, and 300 articles for a thorough examination of the field Highlights new research and promotes innovation in applied areas ranging from food science and forensics to biomedicine and health Presents a one-stop resource for quick access to answers and an in-depth examination of topics in the spectroscopy and spectrometry arenas
Author : Pellegrino Conte
Publisher : Royal Society of Chemistry
ISBN 13 : 1837671265
Total Pages : 461 pages
Book Rating : 4.8/5 (376 download)
Download or read book Environment in a Magnet written by Pellegrino Conte and published by Royal Society of Chemistry. This book was released on 2024-03-04 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global climate change is the most important challenge humankind is facing in the modern era. One of the main scientific concerns is the monitoring of contaminants in the environment, which require the right environmental remediation strategies. In this context, nuclear magnetic resonance (NMR) techniques have a very important role in enabling the discovery of how pollutants are transformed, how they can move and how they can affect human health. This book discusses the present and the future perspectives of NMR techniques for environmental evaluations. It covers, amongst other topics, the importance of NMR as a contamination discovery tool, how to improve sensitivity in environmental NMR, and multiphase NMR for measurement of samples in their natural state. Samples include lubricant oils, soils and porous media. Due to the direct relationship between the environment and human health, there is information dedicated to the use of magnetic resonance imaging (MRI) to monitor human health as related to environmental pollution. There is also a chapter on how NMR is used in cultural heritage to measure artefacts directly affected by environmental pollution. Filling a gap in the literature, the book is for researchers explaining how to apply their knowledge of NMR techniques to solve environmental problems, and for students who want to deepen their understanding of this topic.
Author : Ralf Kircheis
Publisher : Frontiers Media SA
ISBN 13 : 2832544029
Total Pages : 202 pages
Book Rating : 4.8/5 (325 download)
Download or read book The Role of Toll-like Receptors and their Related Signaling Pathways in Viral Infection and Inflammation written by Ralf Kircheis and published by Frontiers Media SA. This book was released on 2024-02-01 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toll-like receptors (TLRs) represent a powerful system for recognition and elimination of pathogen-associated molecular patterns (PAMPs) from bacteria, viruses, and other pathogens and damage-associated molecular patterns (DAMPs) released from dying cells. TLRs are mainly expressed on immune cells, but can also be present on other cell populations. Typical PAMPs include bacterial cell wall components, viral pathogens, or pathogenic nucleic acids, including viral RNA and DNA. Activation of TLRs leads to the production of proinflammatory cytokines and type I interferons which are important for induction of the host immune response against bacterial and viral infections. However, dysregulation and overstimulation can be detrimental leading to hyper-inflammation, sepsis, and loss of tissue integrity. Furthermore, TLRs are involved in the pathogenesis of acute viral infections, including COVID-19. Consequently, TLRs are promising targets for pharmacological intervention and treatment.
Author : Dibakar Bhattacharyya
Publisher : Elsevier
ISBN 13 : 0080537537
Total Pages : 439 pages
Book Rating : 4.0/5 (85 download)
Download or read book New Insights into Membrane Science and Technology: Polymeric and Biofunctional Membranes written by Dibakar Bhattacharyya and published by Elsevier. This book was released on 2003-05-23 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membrane techniques provide a broad science and technology base. Although there are several books in the traditional membrane field, there is a great need for a highly comprehensive book. This refereed book covers materials from highly respected researchers. This title is highly multidisciplinary in nature and should be extremely valuable to scientists and engineers involved in a variety of activities. Students and faculty members around the world will find this title to be an excellent reference book. Invited contributions from leading researchers in the field Coverage of topic is of value to scientists/engineers working in a variety of related fields [separations/reactions, advanced biofunctional materials, contactor designs] Aims to fill market gap for a highly comprehensive book containing advances in both synthetic and biofunctional/bimimetic membranes
