Initiation and Termination of Cylic Nucleotide Action

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Publisher : Academic Press
ISBN 13 : 9780121820602
Total Pages : 892 pages
Book Rating : 4.8/5 (26 download)

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Book Synopsis Initiation and Termination of Cylic Nucleotide Action by :

Download or read book Initiation and Termination of Cylic Nucleotide Action written by and published by Academic Press. This book was released on 1988-06-28 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel approaches for the study of phosphodiesterases and phosphoprotein phosphatases, as well as those of nonmammalian cyclic nucleotide receptors, are emphasized for the first time in the Methods of Enzymology series. New methods for the study of protein kinases are also presented.

Angiogenesis: In Vivo Systems, Part B

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Publisher : Academic Press
ISBN 13 : 0080921663
Total Pages : 460 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Angiogenesis: In Vivo Systems, Part B by :

Download or read book Angiogenesis: In Vivo Systems, Part B written by and published by Academic Press. This book was released on 2009-02-12 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding how angiogenesis "works" and how to control it will have massive implications on the management, treatments, and ultimately the prevention of many common (and not so common) diseases. Angiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance of angiogenesis modulators. In many serious disease states, however, the body loses control over angiogenesis. Diseases that are angiogenesis-dependent result when blood vessels either grow excessively or insufficiently. - Tried-and-tested techniques written by researchers that developed them, used them, and brought them to fruition - Provides the "builder's manual" for essential techniques--a one-stop shop that eliminates needless searching among untested techniques - Includes step-by-step methods for understanding the cell and molecular basis of wound healing, vascular integrin signaling, mechanical signaling in blood vessels, and vascular proteomics

Macromolecular Crystallography, Part C

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Author :
Publisher : Elsevier
ISBN 13 : 0080497098
Total Pages : 405 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Macromolecular Crystallography, Part C by : Charles W. Carter Jr.

Download or read book Macromolecular Crystallography, Part C written by Charles W. Carter Jr. and published by Elsevier. This book was released on 2003-12-15 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding.* Methodological methods in crystals* Methodological methods data analysis

Nitric Oxide, Part F

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Publisher : Academic Press
ISBN 13 : 0080877613
Total Pages : 513 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Nitric Oxide, Part F by :

Download or read book Nitric Oxide, Part F written by and published by Academic Press. This book was released on 2011-09-02 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery that nitrogen monoxide or nitric oxide (NO)is a biologically produced free radical has revolutionized our thinking about physiological and pathological processes. This discovery has ignited enormous interest in the scientific community. When generated at low levels, NO is a signaling molecule, but at high concentration, NO is a cytotoxic molecule. The physiological and pathological processes of NO production and metabolism and its targets, currently areas of intensive research, have important pharmacologic implications for health and disease.

Regulators and Effectors of Small GTPases: Rho Family

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Author :
Publisher : Elsevier
ISBN 13 : 0080479391
Total Pages : 842 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Regulators and Effectors of Small GTPases: Rho Family by :

Download or read book Regulators and Effectors of Small GTPases: Rho Family written by and published by Elsevier. This book was released on 2006-02-21 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Ras superfamily (>150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl and dynamin involved in vesicle budding/fission. These GTPases act as molecular switches and their activities are controlled by a large number of regulatory molecules that affect either GTP loading (guanine nucleotide exchange factors or GEFs) or GTP hydrolysis (GTPase activating proteins or GAPs). In their active state, they interact with a continually increasing, functionally complex array of downstream effectors. Since the last Methods in Enzymology volume on this topic in 2000, Rho GTPases have continued to receive a huge amount of attention. The human genome sequence has revealed the full extent of the Rho GEF and Rho GAP families (over 80 members for each) and the challenge of identifying the molecular interactions and cellular pathways influenced by each of these regulators is a daunting prospect. This new volume, Regulators and Effectors of Small GTPases: Rho Family, describes some of the methods currently being used to examine Rho family GTPase regulation at the biochemical and cellular level. - Describes the methods currently being used to examine Rho family GTPase regulation at the biochemical and cellular levels - Includes new imaging techniques that revolutionize the ability to visualize GTPase activities - Over 150 international contributors

Two-Component Signaling Systems, Part C

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Publisher : Academic Press
ISBN 13 : 0123813484
Total Pages : 495 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Two-Component Signaling Systems, Part C by :

Download or read book Two-Component Signaling Systems, Part C written by and published by Academic Press. This book was released on 2010-03-01 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multicellular organisms must be able to adapt to cellular events to accommodate prevailing conditions. Sensory-response circuits operate by making use of a phosphorylation control mechanism known as the "two-component system." This volume, the third in a three-volume treatment edited by the same group of editors, includes a wide range of methods, including those dealing with the Sln-1 kinase pathway, triazole sensitivity in C. albicans, and histidine kinases in cyanobacteria circadian clock. - Includes time-tested core methods and new innovations applicable to any researcher studing two-component signaling systems or histidine kinases - Methods included are useful to both established researchers and newcomers to the field - Relevant background and reference information given for procedures can be used as a guide to developing protocols in a number of disciplines

Liposomes, Part D

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Publisher : Elsevier
ISBN 13 : 0080522610
Total Pages : 379 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Liposomes, Part D by :

Download or read book Liposomes, Part D written by and published by Elsevier. This book was released on 2004-07-17 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liposomes are cellular structures made up of lipid molecules. Important as a cellular model in the study of basic biology, liposomes are also used in clinical applications such as drug delivery and virus studies. Liposomes Part D is a continuation of previous Methods in Enzymology Liposome volumes A, B, and C. - Covers antibody or ligand targeted liposomes; environment sensitive liposomes; liposomal oligonucleotides; liposomes in vivo

Liposomes, Part B

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Author :
Publisher : Elsevier
ISBN 13 : 008049711X
Total Pages : 517 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Liposomes, Part B by : Nejat Duzgunes

Download or read book Liposomes, Part B written by Nejat Duzgunes and published by Elsevier. This book was released on 2003-11-19 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liposomes are cellular structures made up of lipid molecules. Important as a cellular model in the study of basic biology, liposomes are also used in clinical applications such as drug delivery and virus studies. - Liposomes in Biochemistry - Liposomes in Molecular Cell Biology - Liposomes in Molecular Virology

Biological Mass Spectrometry

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Publisher : Gulf Professional Publishing
ISBN 13 : 9780121828073
Total Pages : 520 pages
Book Rating : 4.8/5 (28 download)

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Book Synopsis Biological Mass Spectrometry by : A.L. Burlingame

Download or read book Biological Mass Spectrometry written by A.L. Burlingame and published by Gulf Professional Publishing. This book was released on 2005-11-28 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes and integrates the techniques of many advances in both chromatographic and mass spectrometric technologies. This book also covers various biophysical applications, such as H/D exchange for study of conformations, protein-protein and protein-metal and ligand interactions. It also describes atto-to-zepto-mole quantitation of 14C and 3H.

Measuring Biological Responses with Automated Microscopy

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Author :
Publisher : Elsevier
ISBN 13 : 0080468985
Total Pages : 736 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Measuring Biological Responses with Automated Microscopy by :

Download or read book Measuring Biological Responses with Automated Microscopy written by and published by Elsevier. This book was released on 2006-11-02 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today-truly an essential publication for researchers in all fields of life sciences.

Constitutive Activity in Receptors and Other Proteins, Part B

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Author :
Publisher : Academic Press
ISBN 13 : 0123812976
Total Pages : 721 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Constitutive Activity in Receptors and Other Proteins, Part B by :

Download or read book Constitutive Activity in Receptors and Other Proteins, Part B written by and published by Academic Press. This book was released on 2010-11-24 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Methods in Enzymology covers the current methodology for the detection and assessment of constitutively active proteins. The chapters written by expert authors who are leaders in the field, provide hints and tricks not available in primary research publications.It is extensively referenced, with useful figures and tables throughout the volume. - Expert authors who are leaders in the field - Extensively referenced and useful figures and tables - Provides hints and tricks to facilitate reproduction of methods

Biology of Serpins

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Publisher : Academic Press
ISBN 13 : 0123864720
Total Pages : 461 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Biology of Serpins by : James Whisstock

Download or read book Biology of Serpins written by James Whisstock and published by Academic Press. This book was released on 2011-06-11 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. This volume of Methods in Ezymology is split into 2 parts and comprehensively covers the subject.

Chromatin and Chromatin Remodeling Enzymes, Part A

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Author :
Publisher : Elsevier
ISBN 13 : 0080497136
Total Pages : 579 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Chromatin and Chromatin Remodeling Enzymes, Part A by : Carl Wu

Download or read book Chromatin and Chromatin Remodeling Enzymes, Part A written by Carl Wu and published by Elsevier. This book was released on 2004-02-20 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the Chromatin remodellng enzymes play an important role in gene transcription.*Histone Bioinformatics*Biochemistry of histones, nucleosomes and chromatin*Molecular cytology of chromatin functions

Hypertheromphilic Enzymes, Part A

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Author :
Publisher : Elsevier
ISBN 13 : 0080496857
Total Pages : 548 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Hypertheromphilic Enzymes, Part A by :

Download or read book Hypertheromphilic Enzymes, Part A written by and published by Elsevier. This book was released on 2001-02-08 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymologyis one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.This volume and its companions (Volumes 31 and 334) cover all current knowledge concerning hyperthermophilic enzymes. Major topics in this volume include enzyme discovery, saccharolytic enzymes, and proteolytic enzymes.

Quinones and Quinone Enzymes, Part A

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Publisher : Elsevier
ISBN 13 : 0080497160
Total Pages : 461 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Quinones and Quinone Enzymes, Part A by : Helmut Sies

Download or read book Quinones and Quinone Enzymes, Part A written by Helmut Sies and published by Elsevier. This book was released on 2004-05-01 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quinones are members of a class of aromatic compounds with two oxygen atoms bonded to the ring as carbonyl groups. This volume covers the role of quinines enzymes in cellular signalling and modulation of gene expression.*Coenzyme Q: Detection and Quinone Reductases*Plasma Membrane Quinone Reductases*Quinones, Cellular Signaling, and Modulation of Gene Expression

Regulators and Effectors of Small GTPases, Part F: Ras Family I

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Author :
Publisher : Elsevier
ISBN 13 : 0080522556
Total Pages : 527 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Regulators and Effectors of Small GTPases, Part F: Ras Family I by :

Download or read book Regulators and Effectors of Small GTPases, Part F: Ras Family I written by and published by Elsevier. This book was released on 2001-04-17 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critically acclaimed laboratory standard for more than 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today, truly an essential publication for researchers in all fields of life sciences.This volume and its companions (Volumes 255, 256, 257, and the forthcoming 325 and 329) cover all biochemical and biological assays currently in use for analyzing the role of small GTPases in these aspects of cell biology at the molecular level.

Combinatorial Chemistry

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Publisher : Academic Press
ISBN 13 : 0121822729
Total Pages : 608 pages
Book Rating : 4.1/5 (218 download)

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Book Synopsis Combinatorial Chemistry by : Guillermo A. Morales

Download or read book Combinatorial Chemistry written by Guillermo A. Morales and published by Academic Press. This book was released on 2003 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combinatorial Chemistry encompasses both the design of compounds for specific pharmacological use and the screening of molecules in high throughput automated tests to find active agents with specific functions. *Analytical techniques *Direct sorting split and pool combinatorial synthesis *Linkers and their applications *Microwave assisted synthesis *Oligosaccharide chemistry *Peptide Synthesis and Screening *Polymer assisted approaches *Small molecule and heterocycle synthesis.