Inflammation And Lung Cancer

Download Inflammation And Lung Cancer full books in PDF, epub, and Kindle. Read online Inflammation And Lung Cancer ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Inflammation and Lung Cancer

Author : Steven M. Dubinett
Publisher : Springer
ISBN 13 : 9781493945115
Total Pages : 0 pages
Book Rating : 4.9/5 (451 download)

DOWNLOAD NOW!

Book Synopsis Inflammation and Lung Cancer by : Steven M. Dubinett

Download or read book Inflammation and Lung Cancer written by Steven M. Dubinett and published by Springer. This book was released on 2016-10-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years there have been various discoveries connecting inflammation and lung cancer and clearly there is growing interest in this area of cancer research. The link between unresolved inflammation and cancer has been well established with estimates that 15% of cancer deaths are inflammation‐related. Evidence for this link includes the following: a) some inflammatory diseases are associated with increased risk of cancer development; b) inflammatory mediators are present surrounding and within most tumors; c) overexpression of inflammatory cytokines increases cancer development and progression in murine studies; d) inhibition of inflammatory mediators decreases cancer development and progression; and e) the use of non‐steroidal anti‐inflammatory drugs (NSAIDs) has been found to decrease cancer incidence and delay progression. The volume will present aspects of the inflammatory tumor microenvironment (TME), its many roles in tumor progression and metastasis, including creation of a hypoxic environment, increased angiogenesis and invasion, changes in expression of micro‐RNAs (miRNAs) and an increase in a stem cell phenotype. The book will also cover the mechanisms of inflammatory mediators. Chronic overexpression of inflammatory mediators in the TME, as seen in smokers and patients with non‐small cell lung cancer (NSCLC), can also lead to increased tumor initiation, progression, invasion and metastasis. The volume will provide a comprehensive perspective of the latest findings and summaries of progress made regarding inflammation and its connection to lung cancer.

Inflammation and Lung Cancer

Author : Steven M. Dubinett
Publisher : Springer
ISBN 13 : 1493927248
Total Pages : 212 pages
Book Rating : 4.4/5 (939 download)

DOWNLOAD NOW!

Book Synopsis Inflammation and Lung Cancer by : Steven M. Dubinett

Download or read book Inflammation and Lung Cancer written by Steven M. Dubinett and published by Springer. This book was released on 2015-06-24 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years there have been various discoveries connecting inflammation and lung cancer and clearly there is growing interest in this area of cancer research. The link between unresolved inflammation and cancer has been well established with estimates that 15% of cancer deaths are inflammation‐related. Evidence for this link includes the following: a) some inflammatory diseases are associated with increased risk of cancer development; b) inflammatory mediators are present surrounding and within most tumors; c) overexpression of inflammatory cytokines increases cancer development and progression in murine studies; d) inhibition of inflammatory mediators decreases cancer development and progression; and e) the use of non‐steroidal anti‐inflammatory drugs (NSAIDs) has been found to decrease cancer incidence and delay progression. The volume will present aspects of the inflammatory tumor microenvironment (TME), its many roles in tumor progression and metastasis, including creation of a hypoxic environment, increased angiogenesis and invasion, changes in expression of micro‐RNAs (miRNAs) and an increase in a stem cell phenotype. The book will also cover the mechanisms of inflammatory mediators. Chronic overexpression of inflammatory mediators in the TME, as seen in smokers and patients with non‐small cell lung cancer (NSCLC), can also lead to increased tumor initiation, progression, invasion and metastasis. The volume will provide a comprehensive perspective of the latest findings and summaries of progress made regarding inflammation and its connection to lung cancer.

Inflammation and Cancer

Author : Brendan J. Jenkins
Publisher : Humana
ISBN 13 : 9781071633304
Total Pages : 0 pages
Book Rating : 4.6/5 (333 download)

DOWNLOAD NOW!

Book Synopsis Inflammation and Cancer by : Brendan J. Jenkins

Download or read book Inflammation and Cancer written by Brendan J. Jenkins and published by Humana. This book was released on 2023-06-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition volume expands on the previous edition with an update on the broad spectrum of research models, techniques, and protocols used in laboratories by basic and clinical researchers. The chapters in this book are divided into two parts. Part One discusses the latest findings on the development and characterization of representative research models for chronic immune-based diseases and inflammation-associated cancers. Part Two covers biochemical, molecular, and cellular biological techniques that are commonly used to dissect the molecular mechanisms and cellular processes that drive the pathogenesis of certain disease states. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Inflammation and Cancer: Methods and Protocols, Second Edition is a valuable resource for those with a diverse range of laboratory-based experience, ranging from novice undergraduate students to established basic or clinical researchers who wish to diversify their existing portfolio of practical knowledge in the field.

Lung Inflammation in Health and Disease, Volume I

Author : Yong-Xiao Wang
Publisher : Springer Nature
ISBN 13 : 3030630463
Total Pages : 412 pages
Book Rating : 4.0/5 (36 download)

DOWNLOAD NOW!

Book Synopsis Lung Inflammation in Health and Disease, Volume I by : Yong-Xiao Wang

Download or read book Lung Inflammation in Health and Disease, Volume I written by Yong-Xiao Wang and published by Springer Nature. This book was released on 2021-03-31 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Respiratory diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma, the most common chronic disease. Each year, tens of millions of people develop and can die from from respiratory infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for those affected. Current treatment options for lung disease are neither effective, nor condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases is not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung disease, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, and students with new perspectives and concepts. The editors hope these books will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.

Inflammation and Cancer

Author : Bharat B. Aggarwal
Publisher : Springer
ISBN 13 : 3034808372
Total Pages : 489 pages
Book Rating : 4.0/5 (348 download)

DOWNLOAD NOW!

Book Synopsis Inflammation and Cancer by : Bharat B. Aggarwal

Download or read book Inflammation and Cancer written by Bharat B. Aggarwal and published by Springer. This book was released on 2014-05-12 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems

Author : Kamal Dua
Publisher : Academic Press
ISBN 13 : 0128208880
Total Pages : 620 pages
Book Rating : 4.1/5 (282 download)

DOWNLOAD NOW!

Book Synopsis Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems by : Kamal Dua

Download or read book Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems written by Kamal Dua and published by Academic Press. This book was released on 2020-08-04 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models. The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development. Explores recent perspectives and challenges regarding the management and diagnosis of chronic respiratory diseases Provides insights into how advanced drug delivery systems can be effectively formulated and delivered for the management of various pulmonary diseases Includes the most recent information on diagnostic methods and treatment strategies using controlled drug delivery systems (including nanotechnology)

Systems Biology of Cancer

Author : Sam Thiagalingam
Publisher : Cambridge University Press
ISBN 13 : 0521493390
Total Pages : 597 pages
Book Rating : 4.5/5 (214 download)

DOWNLOAD NOW!

Book Synopsis Systems Biology of Cancer by : Sam Thiagalingam

Download or read book Systems Biology of Cancer written by Sam Thiagalingam and published by Cambridge University Press. This book was released on 2015-04-09 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.

How Tobacco Smoke Causes Disease

Author :
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

DOWNLOAD NOW!

Book Synopsis How Tobacco Smoke Causes Disease by :

Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

From Chronic Inflammation to Cancer: How Far Can Immunotherapy Go?

Author : Zhaogang Yang
Publisher : Frontiers Media SA
ISBN 13 : 2889744299
Total Pages : 142 pages
Book Rating : 4.8/5 (897 download)

DOWNLOAD NOW!

Book Synopsis From Chronic Inflammation to Cancer: How Far Can Immunotherapy Go? by : Zhaogang Yang

Download or read book From Chronic Inflammation to Cancer: How Far Can Immunotherapy Go? written by Zhaogang Yang and published by Frontiers Media SA. This book was released on 2022-02-18 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Link Between Inflammation and Cancer

Author : Angus G. Dalgleish
Publisher : Springer Science & Business Media
ISBN 13 : 0387262830
Total Pages : 260 pages
Book Rating : 4.3/5 (872 download)

DOWNLOAD NOW!

Book Synopsis The Link Between Inflammation and Cancer by : Angus G. Dalgleish

Download or read book The Link Between Inflammation and Cancer written by Angus G. Dalgleish and published by Springer Science & Business Media. This book was released on 2006-03-05 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: A link between inflammation and cancer has been established many years ago, yet it is only recently that the potential significance of this connection has become apparent. Although several examples of chronic inflammatory conditions, often induced by persistent irritation and/or infection, developing into cancer have been known for some time, there has been a notable resistance to contemplate the possibility that this association may apply in a causative way to other cancers. Examples for such progression from chronic inflammation to cancer are colon carcinoma developing with increased frequency in patients with ulcerative colitis, and the increased incidence of bladder cancer in patients suffering from chronic Schistosoma infection. Inflammation and cancer have been recognized to be linked in another context for many years, i.e., with regards to pathologies resembling chronic lacerations or 'wounds that do not heal.' More recently, the immunology of wound healing has given us clues as to the mechanistic link between inflammation and cancer, in as much as wounds and chronic inflammation turn off local cell-mediated immune responses and switch on growth factor release as well the growth of new blood vessels - angiogenesis. Both of these are features of most types of tumours, which suggest that tumours may require an immunologically shielded milieu and a growth factor-rich environment.

Inflammation and Metastasis

Author : Yoshiro Maru
Publisher : Springer Nature
ISBN 13 : 9811617570
Total Pages : 531 pages
Book Rating : 4.8/5 (116 download)

DOWNLOAD NOW!

Book Synopsis Inflammation and Metastasis by : Yoshiro Maru

Download or read book Inflammation and Metastasis written by Yoshiro Maru and published by Springer Nature. This book was released on 2021-10-06 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, now in a thoroughly revised and updated second edition, provides the latest information on cancer metastasis from the perspective of inflammation and presents new ideas on the complicated mechanisms of metastasis and potential therapeutic targets. Key features include discussion of mechanisms recently identified to be involved in the resolution phase of inflammation, presentation of the latest evidence regarding the roles of endogenous TLR4 ligands in metastasis, and thorough explanation of the concept of homeostatic inflammation and current understanding of the significance of its dysregulation for metastasis. Structure-based thinking is another important element of the book, and it is proposed that inflammation forms a functional triangle with angiogenesis and coagulation, at the center of which cancer is located. Examples of the many additional specific topics covered in this edition include the functional involvement of new types of RNA in cancer, the insights offered by recent advances in bioinformatics, and the potential of a casein kinase 1α inhibitor in the treatment of acute myeloid leukemia. The book will be a valuable update and resource for both experienced and younger researchers. Homeostasis, originated from an idea of internal milieu by Claude Bernard, is eventually maintained by endogenous elements. The essential features of inflammation are leukocyte mobilization and increased vascular permeability, which could take place in many homeostatic or physiological conditions at low levels. Homeostatic inflammation is a concept to explain pathological settings such as metastasis in which irrespective of its level those inflammatory features are misused with endogenous molecules (see Chap. 14,15). As inflammation comprises many biological fields, targeting a single molecule for a disease could potentially make a therapeutic contribution to other diseases. For example, one focus is applied here to the roles of calprotectin in lung metastasis, which is implicated in psychiatric disorders and COVID-19 as shown by recent evidence.

Mediators of Pulmonary Inflammation

Author : Michael A. Bray
Publisher : CRC Press
ISBN 13 : 9780824784423
Total Pages : 688 pages
Book Rating : 4.7/5 (844 download)

DOWNLOAD NOW!

Book Synopsis Mediators of Pulmonary Inflammation by : Michael A. Bray

Download or read book Mediators of Pulmonary Inflammation written by Michael A. Bray and published by CRC Press. This book was released on 1991-07-19 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most of the contributions concentrate largely on dramatic new findings linking asthma and the inflammatory process, but the hope is to encourage more research into the role of inflammation in other diseases as well (lung cancer and lung infections are not covered here). The chapters cover some of th

Cancer and Inflammation

Author : Douglas W. Morgan
Publisher : Springer
ISBN 13 : 3034878613
Total Pages : 216 pages
Book Rating : 4.0/5 (348 download)

DOWNLOAD NOW!

Book Synopsis Cancer and Inflammation by : Douglas W. Morgan

Download or read book Cancer and Inflammation written by Douglas W. Morgan and published by Springer. This book was released on 2012-12-06 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: How are cancer and inflammation interrelated mechanistically and clinically? Though extensive literature exists on the topic "Cancer and Inflammation", there are relatively few texts that have truly integrated the two in spite of the many common mechanisms shared by their processes. Certainly, areas such as cytokines, growth factors, proliferation, signal transduction and angiogenesis, for example, are found in both. Yet, the dynamics of how these common mechanisms are maybe interrelated in the pathologies of the two is not widely covered. Such coverage, as presented in this volume, may help further understanding and bring new approaches to therapeutics. The first section of the book discusses inflammatory mechanisms, studied in cellular and animal studies. The second part concentrates on clinical studies with antiinflammatory drugs in cancer treatment. The volume is written for biomedical researchers in the health care industry and in academia who are working in these areas.

Lung Cancer

Author : Kathy Gately
Publisher : Nova Science Publishers
ISBN 13 : 9781626184473
Total Pages : 0 pages
Book Rating : 4.1/5 (844 download)

DOWNLOAD NOW!

Book Synopsis Lung Cancer by : Kathy Gately

Download or read book Lung Cancer written by Kathy Gately and published by Nova Science Publishers. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lung cancer is the leading cause of cancer related death in both men and women world-wide. The impact of this devastating disease on society is phenomenal with patient outcomes only marginally improving over the past four decades and the cost of treatment constantly rising. Recent technological advances in how we diagnose cancer and the advent of targeted therapies and a more personalised approach to patient treatment has paved the way for real improvements in lung cancer management. This book provides a comprehensive overview of lung cancer in the 21st century. It describes in detail the histopathology and staging of tumours. It outlines the epidemiology of the disease and the role of chronic obstructive pulmonary disease (COPD), cigarette smoke, radon and occupational exposures in the incidence of lung cancer. An in depth overview of the current recommended treatment options for lung cancer patients depending on stage is presented, highlighting the relevant clinical trials that have changed clinical practice. An insight into many of the molecular mechanisms involved in resistance to therapy and recent developments in targeted therapies are reviewed extensively. Finally, the molecular biology of lung carcinogenesis, progression and the link between inflammation and lung cancer are examined.

Perioperative Inflammation as Triggering Origin of Metastasis Development

Author : Michael W. Retsky
Publisher : Springer
ISBN 13 : 3319579436
Total Pages : 236 pages
Book Rating : 4.3/5 (195 download)

DOWNLOAD NOW!

Book Synopsis Perioperative Inflammation as Triggering Origin of Metastasis Development by : Michael W. Retsky

Download or read book Perioperative Inflammation as Triggering Origin of Metastasis Development written by Michael W. Retsky and published by Springer. This book was released on 2017-06-28 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book will explain previously unconnected clinical data such as why mammography works better for women age 50-59 than it does for women age 40-49, why adjuvant chemotherapy works best for premenopausal patients with positive lymph nodes, and it may also explain the racial disparity in outcome. In particular, it points to the perioperative period when systemic inflammation persists for a week or so. This can lead to a variety of mechanisms whereby single cancer cells (perhaps from the marrow) begin division and angiogenesis of dormant avascular micrometastases occurs leading to early relapses. With chapters presented from distinguished scientists and physicians in a variety of specialties that relate to and border the effects we present, this volume can be used as a reference for practicing physicians and as a jumping-off point for researchers to explore new therapeutic opportunities.

Inflammation and Cancer

Author : Brendan J. Jenkins
Publisher : Springer Nature
ISBN 13 : 1071633317
Total Pages : 373 pages
Book Rating : 4.0/5 (716 download)

DOWNLOAD NOW!

Book Synopsis Inflammation and Cancer by : Brendan J. Jenkins

Download or read book Inflammation and Cancer written by Brendan J. Jenkins and published by Springer Nature. This book was released on 2023-06-24 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition volume expands on the previous edition with an update on the broad spectrum of research models, techniques, and protocols used in laboratories by basic and clinical researchers. The chapters in this book are divided into two parts. Part One discusses the latest findings on the development and characterization of representative research models for chronic immune-based diseases and inflammation-associated cancers. Part Two covers biochemical, molecular, and cellular biological techniques that are commonly used to dissect the molecular mechanisms and cellular processes that drive the pathogenesis of certain disease states. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Inflammation and Cancer: Methods and Protocols, Second Edition is a valuable resource for those with a diverse range of laboratory-based experience, ranging from novice undergraduate students to established basic or clinical researchers who wish to diversify their existing portfolio of practical knowledge in the field.

Cancer and Inflammation Mechanisms

Author : Yusuke Hiraku
Publisher : John Wiley & Sons
ISBN 13 : 1118826558
Total Pages : 467 pages
Book Rating : 4.1/5 (188 download)

DOWNLOAD NOW!

Book Synopsis Cancer and Inflammation Mechanisms by : Yusuke Hiraku

Download or read book Cancer and Inflammation Mechanisms written by Yusuke Hiraku and published by John Wiley & Sons. This book was released on 2014-03-19 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new perspective on the link between inflammation and cancer Inflammation is the human body’s normal biological response to threats in the modern world, as well as a defense against the harmful influence of pathogens, the environment, and poor nutrition. But what happens when the inflammatory response is triggered repeatedly and sustained for long periods of time? Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects discusses the mechanisms by which chronic inflammation can lead to cancer, the various causative agents, and possible prevention methods. A compilation of the latest information coming out of the various fields of cancer research, this book provides a detailed look at inflammation-related carcinogenesis from the perspective of researchers at the forefront of the field. It takes an interdisciplinary approach to the topic, and provides comprehensive information about the major factors at work in inflammation, cancer, and the intersection of the two conditions. Topics include: A general overview of inflammation-related cancer The biochemistry of inflammation and its effects on DNA Molecular biology and the role of microRNA in carcinogenesis Specific causative agents including oncogenic viruses, asbestos, and nanomaterial Anti-inflammatories, nutraceuticals, and other preventative measures A deeper understanding of the mechanisms behind inflammation-related carcinogenesis can lead to better patient outcomes by improving diagnostics and prevention, as well as altering the approach to treatment. Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects provides the knowledge base researchers need to push the field forward.