Indole

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The Chemistry of Indoles

Author : Richard Sundberg
Publisher : Elsevier
ISBN 13 : 0323147860
Total Pages : 505 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis The Chemistry of Indoles by : Richard Sundberg

Download or read book The Chemistry of Indoles written by Richard Sundberg and published by Elsevier. This book was released on 2012-12-02 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Chemistry, Volume 18: The Chemistry of Indoles discusses the chemistry of indole derivatives. This book explores the potent biological activity of several indole derivatives and explains the structure of indole alkaloids. Organized into 10 chapters, this monograph starts with an overview of the most important types of reactions of the indole ring on a mechanical basis. This text then proceeds to review the methods of synthesizing indoles and describes the oxidations and rearrangements of indole derivatives. Other chapters explore the special features of the synthesis and reactivity of hydroxyindoles, acylindoles, and aminoindoles. This book discusses as well the properties of carboxyl groups, which is substituted on the benzenoid ring of the indole nucleus that is typical of aromatic carboxylic acids. The final chapter deals with the certain classes of indoles that are found in nature. Chemists, researchers, and readers interested in the chemistry of indoles will find this book extremely useful.

Indole Ring Synthesis

Author : Gordon W. Gribble
Publisher : John Wiley & Sons
ISBN 13 : 0470512180
Total Pages : 704 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Indole Ring Synthesis by : Gordon W. Gribble

Download or read book Indole Ring Synthesis written by Gordon W. Gribble and published by John Wiley & Sons. This book was released on 2016-08-08 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the myriad of heterocycles known to man, the indole ring stands foremost for its remarkably versatile chemistry, its enormous range of biological activities, and its ubiquity in the terrestrial and marine environments. The indole ring continues to be discovered in natural products and to be employed in man-made pharmaceuticals and other materials. Given the enormous resurgence in indole ring synthesis over the past decade — highlighted by the power of transition metal catalysis — this authoritative guide addresses the need for a comprehensive presentation of the myriad of methods for constructing the indole ring, from the ancient to the modern, and from the obscure to the well-known. Following presentation of the classic indole ring syntheses and many newer methods, coverage continues with indole ring syntheses via pyrroles, indolines, oxindoles, isatins, radical and photochemical reactions, aryne cycloadditions. This extensive volume concludes with the modern transition metal–catalyzed indole ring syntheses that utilize copper, palladium, rhodium, gold, ruthenium, platinum, and other metals to fashion the indole ring Indole Ring Synthesis is a comprehensive, authoritative and up-to-date guide to the synthesis of this important heterocycle for organic chemists, pharmaceutical researchers and those interested in the chemistry of natural products.

Indoles

Author : Richard J. Sundberg
Publisher : Elsevier
ISBN 13 : 0080534619
Total Pages : 193 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Indoles by : Richard J. Sundberg

Download or read book Indoles written by Richard J. Sundberg and published by Elsevier. This book was released on 1996-05-28 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Indoles continue to be of great interest to the pharmaceutical industry and at the current time several thousand specific new derivatives are reported annually. Research has been driven by the wide range of indole derivatives which occur in nature and through the biological activity of many indole derivatives, of both natural and synthetic origin.This book provides a systematic guide to the most useful and important reactions in the field for both synthesis and synthetic modification of the indole ring. While including the most recently developed and promising methods, it also updates informationavailable on classical methods to give the reader an up-to-date and comprehensive view of the subject. The methods are illustrated by procedures drawn from the literature and by tables including examples chosen to indicate both the scope of applicabilityand variations in methodology. The organization of the book is based on the retrosynthetic concept of identifying the bond(s) formed in the reaction, which in turn identifies potential starting materials. - Includes systematic summaries of the most important methods for the construction of indoles from aromatic precursors - Discusses methods for preparing indoles by annelation of pyrroles - Covers methods for adding or modifying substituent groups, including methods for introducing the tryptamine and tryptophan side-chainsExamines reduction/oxidation reactions that are specific for indoles - Considers use of cycloaddition reactions for synthetic elaboration of indoles

Comprehensive Natural Products III

Author :
Publisher : Elsevier
ISBN 13 : 0081026919
Total Pages : 4266 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Comprehensive Natural Products III by :

Download or read book Comprehensive Natural Products III written by and published by Elsevier. This book was released on 2020-07-22 with total page 4266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Natural Products III, Third Edition, Seven Volume Set updates and complements the previous two editions, including recent advances in cofactor chemistry, structural diversity of natural products and secondary metabolites, enzymes and enzyme mechanisms and new bioinformatics tools. Natural products research is a dynamic discipline at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids and enzymes. This book reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine and to stimulate new ideas among the established natural products community. Provides readers with an in-depth review of current natural products research and a critical insight into the future direction of the field Bridges the gap in knowledge by covering developments in the field since the second edition published in 2010 Split into 7 sections on key topics to allow students, researchers and professionals to find relevant information quickly and easily Ensures that the knowledge within is easily understood by and applicable to a large audience

Cruciferous Vegetables, Isothiocyanates and Indoles

Author : International Agency for Research on Cancer
Publisher : IARC
ISBN 13 : 9789283230090
Total Pages : 282 pages
Book Rating : 4.2/5 (3 download)

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Book Synopsis Cruciferous Vegetables, Isothiocyanates and Indoles by : International Agency for Research on Cancer

Download or read book Cruciferous Vegetables, Isothiocyanates and Indoles written by International Agency for Research on Cancer and published by IARC. This book was released on 2004 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication sets outs the findings of an IARC Working Group, held in Lyon, France in November 2003, which considered the benefits of a diet rich in cruciferous vegetables in helping to reduce the risk of various cancers. Cruciferous vegetables, such as broccoli, cabbage, cauliflower, watercress and brussel sprouts, contain substantial amounts of compounds which have been shown to inhibit the growth of cancers. This publication reviews current knowledge on the topic, including data from human, experimental and mechanistic studies, as well as making recommendations for future research and public health policy options.

Indole Ring Synthesis

Author : Gordon W. Gribble
Publisher : John Wiley & Sons
ISBN 13 : 1118683056
Total Pages : 704 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Indole Ring Synthesis by : Gordon W. Gribble

Download or read book Indole Ring Synthesis written by Gordon W. Gribble and published by John Wiley & Sons. This book was released on 2016-06-06 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the myriad of heterocycles known to man, the indole ring stands foremost for its remarkably versatile chemistry, its enormous range of biological activities, and its ubiquity in the terrestrial and marine environments. The indole ring continues to be discovered in natural products and to be employed in man-made pharmaceuticals and other materials. Given the enormous resurgence in indole ring synthesis over the past decade — highlighted by the power of transition metal catalysis — this authoritative guide addresses the need for a comprehensive presentation of the myriad of methods for constructing the indole ring, from the ancient to the modern, and from the obscure to the well-known. Following presentation of the classic indole ring syntheses and many newer methods, coverage continues with indole ring syntheses via pyrroles, indolines, oxindoles, isatins, radical and photochemical reactions, aryne cycloadditions. This extensive volume concludes with the modern transition metal–catalyzed indole ring syntheses that utilize copper, palladium, rhodium, gold, ruthenium, platinum, and other metals to fashion the indole ring Indole Ring Synthesis is a comprehensive, authoritative and up-to-date guide to the synthesis of this important heterocycle for organic chemists, pharmaceutical researchers and those interested in the chemistry of natural products.

Indoles, Volume 25, Part 3

Author : William J. Houlihan
Publisher : John Wiley & Sons
ISBN 13 : 0470188421
Total Pages : 601 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis Indoles, Volume 25, Part 3 by : William J. Houlihan

Download or read book Indoles, Volume 25, Part 3 written by William J. Houlihan and published by John Wiley & Sons. This book was released on 2009-09-15 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Names, Synonyms, and Structures of Organic Compounds

Author : David R. Lide
Publisher : CRC Press
ISBN 13 : 9780849304057
Total Pages : 944 pages
Book Rating : 4.3/5 (4 download)

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Book Synopsis Names, Synonyms, and Structures of Organic Compounds by : David R. Lide

Download or read book Names, Synonyms, and Structures of Organic Compounds written by David R. Lide and published by CRC Press. This book was released on 1994-12-28 with total page 944 pages. Available in PDF, EPUB and Kindle. Book excerpt: Names, Synonyms, and Structures of Organic Compounds provides critical information on the identity of chemicals and allows easy cross referencing among the diverse nomenclatures used by the various scientific disciplines. The compounds selected include most common organic compounds: pesticides, alternative refrigerants, priority pollutants, and other compounds of commercial and environmental importance. This excellent reference provides names, synonyms, molecular formulas, and CAS Registry Numbers for 27,500 organic compounds. The compendium contains 135,000 synonyms and 20,000 chemical structures. Compounds are arranged in ascending order of CAS Registry Numbers. For your convenience, Names, Synonyms, and Structures of Organic Compounds is indexed both by Name/Synonym and Molecular Formula. For all researchers, students, librarians, and professionals working with chemicals, Names, Synonyms, and Structures of Organic Compounds is a must! It is particularly useful to anyone working with organic compounds who has a common or trade name of a compound and needs to determine its CAS Registry number.

Heterocyclic Scaffolds II:

Author : Gordon W. Gribble
Publisher : Springer Science & Business Media
ISBN 13 : 3642157327
Total Pages : 498 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Heterocyclic Scaffolds II: by : Gordon W. Gribble

Download or read book Heterocyclic Scaffolds II: written by Gordon W. Gribble and published by Springer Science & Business Media. This book was released on 2010-10-09 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Richard J. Sundberg Electrophilic Substitution Reactions of Indoles Tara L.S. Kishbaugh Reactions of Indole with Nucleophiles Erin Pelkey Metalation of Indole Jie Jack Li ∙ Gordon W. Gribble Metal-Catalyzed Cross-Coupling Reactions for Indoles Jeanese C. Badenock Radical Reactions of Indole Fariborz Firooznia ∙ Robert F. Kester ∙ Steven J. Berthel [2+2], [3+2] and [2+2+2] Cycloaddition Reactions of Indole Derivatives Robert F. Kester ∙ Steven J. Berthel ∙ Fariborz Firooznia [4+2] Cycloaddition Reactions of Indole Derivatives Jonathon S. Russel Oxindoles and Spirocyclic Variations: Strategies for C3 Functionalization Liangfeng Fu Advances in the Total Syntheses of Complex Indole Natural Products

H-Z

Author : Friedrich W. Derz
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3112322096
Total Pages : 972 pages
Book Rating : 4.1/5 (123 download)

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Book Synopsis H-Z by : Friedrich W. Derz

Download or read book H-Z written by Friedrich W. Derz and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-05-18 with total page 972 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "H-Z".

Organic Photochemistry

Author : V. Ramamurthy
Publisher : CRC Press
ISBN 13 : 9780824700126
Total Pages : 612 pages
Book Rating : 4.7/5 (1 download)

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Book Synopsis Organic Photochemistry by : V. Ramamurthy

Download or read book Organic Photochemistry written by V. Ramamurthy and published by CRC Press. This book was released on 1997-06-26 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Features surveys of all areas of organic, inorganic, physical and biological photochemistry. The text serves as a source of scientific findings pertinent to chemistry and biochemistry. It addresses the state of developments in the field, employing reviews of active research, including recent innovations, techniques and applications.

Indole

Author : Bridget Pratt
Publisher :
ISBN 13 : 9781536147773
Total Pages : 160 pages
Book Rating : 4.1/5 (477 download)

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Book Synopsis Indole by : Bridget Pratt

Download or read book Indole written by Bridget Pratt and published by . This book was released on 2019-03-12 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the foremost chapter of Indole: Synthesis, Functions and Reactions, derivatives of hydrogenated pyrido[4,3-b]indoles as potential neuroprotectors have been synthesized. Different substituents were introduced into position 8 of the carboline fragment of the molecule: methyl-, methoxy-, fluorine- and chlorine-ones. Biological tests have shown that all the studied compounds can modulate glutamate-dependent uptake of calcium ions in rats cerebral cortex synaptosomes. The authors go on to discuss how mushrooms and their mycelia from in vitro cultures have become increasingly common study subjects due to their health-promoting potential. The most frequently demonstrated properties of these mushrooms include antioxidative, anticancer, anti-inflammatory, immunostimulatory and anti-depressive effects. This activity stems from numerous mushroom metabolites, bioelements and physiologically active substances, including indole compounds. The final chapter provides an overview of the diverse synthetic approaches to generate pyrimido[4,5-b]indoles. Pyrimido-indoles are tricyclic ring systems produced when an indole group is fused with a pyrimidine ring. Of the two possible isomers of this ring system, the pyrimido[4,5-b]indoles are of particular interest relative to pyrimido[5,4-b]indoles due to their presence in a wide range of pharmacologically active molecules.

Chemicals and Products Provided for in the Chemical Appendix to the Tariff Schedules of the United States--in Alphabetical Order

Author : Edmund D. Cappuccilli
Publisher :
ISBN 13 :
Total Pages : 604 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Chemicals and Products Provided for in the Chemical Appendix to the Tariff Schedules of the United States--in Alphabetical Order by : Edmund D. Cappuccilli

Download or read book Chemicals and Products Provided for in the Chemical Appendix to the Tariff Schedules of the United States--in Alphabetical Order written by Edmund D. Cappuccilli and published by . This book was released on 1980 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Watts' Dictionary of Chemistry, Revised and Entirely Rewritten

Author : Henry Watts
Publisher :
ISBN 13 :
Total Pages : 880 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Watts' Dictionary of Chemistry, Revised and Entirely Rewritten by : Henry Watts

Download or read book Watts' Dictionary of Chemistry, Revised and Entirely Rewritten written by Henry Watts and published by . This book was released on 1906 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Current Medicinal Chemistry

Author :
Publisher :
ISBN 13 :
Total Pages : 90 pages
Book Rating : 4./5 ( download)

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Book Synopsis Current Medicinal Chemistry by :

Download or read book Current Medicinal Chemistry written by and published by . This book was released on 1998-10 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Plant Secondary Metabolism

Author : David S. Seigler
Publisher : Springer Science & Business Media
ISBN 13 : 9780412019814
Total Pages : 774 pages
Book Rating : 4.0/5 (198 download)

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Book Synopsis Plant Secondary Metabolism by : David S. Seigler

Download or read book Plant Secondary Metabolism written by David S. Seigler and published by Springer Science & Business Media. This book was released on 1998-12-31 with total page 774 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Secondary Metabolism presents a basic understanding of the origin of the compounds, the nature of the precursors involved, and the basic reactions, mechanisms, and stereochemistry. The origin of groups of secondary metabolites is linked to evolutionary principles, and their biological activity is viewed in a context of chemical ecology. Topics are treated comprehensively, enabling the reader to understand not only a particular group of compounds, but also how each group fits into the whole. In addition, the text allows readers to systematically survey various secondary metabolites and gain a quick working knowledge, which can be applied to problems in a particular field. Those researchers and students who will be most intrigued by this publication's broad overview on plant secondary metabolites come from a diverse range of disciplines, including agronomy, anthropology, biochemistry, biology, botany, chemistry, ecology, entomology, food science, forestry, geology, horticulture, pharmacognosy, plant biology, plant sciences, toxicology, and zoology.

Toxic Substances Control Act : Candidate List of Chemical Substances

Author :
Publisher :
ISBN 13 :
Total Pages : 688 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Toxic Substances Control Act : Candidate List of Chemical Substances by :

Download or read book Toxic Substances Control Act : Candidate List of Chemical Substances written by and published by . This book was released on 1977 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: