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In Vitro Percutaneous Absorption
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Book Synopsis In Vitro Percutaneous Absorption by : Robert L. Bronaugh
Download or read book In Vitro Percutaneous Absorption written by Robert L. Bronaugh and published by CRC Press. This book was released on 2023-06-14 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all major areas of interest in the rapidly expanding field of in vitro methods for percutaneous absorption studies. Specific areas discussed include diffusion cell design, receptor fluid, preparation of skin, and temperature. The book covers experimental methodology, as well as the underlying principles and fundamentals that help professionals and students gain an understanding of the basis for currently used methodology.
Book Synopsis Percutaneous Absorption by : Robert L. Bronaugh
Download or read book Percutaneous Absorption written by Robert L. Bronaugh and published by CRC Press. This book was released on 1999-05-28 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since publication of the Second Edition in 1989, numerous innovations have occurred that affect the way scientists look at issues in the field of percutaneous absorption. Focusing on recent advances as well as updating and expanding the scope of topics covered in the previous edition, Percutaneous Absorption, Third Edition provides thorough coverage of the skin's role as an important portal of entry for chemicals into the body. Assembles the work of nearly 80 experts-30 more than the Second Edition-into a unified, comprehensive volume that contains the latest ideas and research! Complete with nearly 600 drawings, photographs, equations, and tables and more than 1600 bibliographic citations of pertinent literature, Percutaneous Absorption, Third Edition details the applied biology of percutaneous penetration factors that affect skin permeation, such as age, vehicles, metabolism, hydration of skin, and chemical structure in vivo and in vitro techniques for measuring absorption, examining factors influencing methodology such as animal models, volatility of test compound, multiple dosage, and artificial membranes procedures for use in transdermal delivery, exploring topics such as effects of penetration enhancers on absorption, optimizing absorption, and the topical delivery of drugs to muscle tissue And presents new chapters on mathematical models cutaneous metabolism prediction of percutaneous absorption in vitro absorption methodology dermal decontamination concentration of chemicals in skin transdermal drug delivery mechanisms of absorption safety evaluation of cosmetics absorption of drugs and cosmetic ingredients nail penetration Emphasizes human applications-particularly useful for pharmacists, pharmacologists, dermatologists, cosmetic scientists, biochemists, toxicologists, public health officials, manufacturers of cosmetic and toiletry products, and graduate students in these disciplines! An invaluable reference source for readers who need to keep up with the latest developments in the field, Percutaneous Absorption, Third Edition is also an excellent experimental guide for laboratory personnel.
Book Synopsis In Vitro Percutaneous Absorption Studies by : Linda Jack
Download or read book In Vitro Percutaneous Absorption Studies written by Linda Jack and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis In Vitro Percutaneous Absorption by : Robert L. Bronaugh
Download or read book In Vitro Percutaneous Absorption written by Robert L. Bronaugh and published by CRC Press. This book was released on 2020-12-18 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all major areas of interest in the rapidly expanding field of in vitro methods for percutaneous absorption studies. Specific areas discussed include diffusion cell design, receptor fluid, preparation of skin, and temperature. The book covers experimental methodology, as well as the underlying principles and fundamentals that help professionals and students gain an understanding of the basis for currently used methodology.
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 428: Skin Absorption: In Vitro Method by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 428: Skin Absorption: In Vitro Method written by OECD and published by OECD Publishing. This book was released on 2004-11-23 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test method has been designed to provide information on absorption of a test substance, (ideally radiolabelled), applied to the surface of a skin sample separating the two chambers (a donor chamber and a receptor chamber) of a diffusion cell ...
Book Synopsis Dermal Absorption and Toxicity Assessment by : Michael S. Roberts
Download or read book Dermal Absorption and Toxicity Assessment written by Michael S. Roberts and published by CRC Press. This book was released on 2007-12-14 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: The source Dermal Absorption and Toxicity Assessment supplies a state-of-the-art overview of the dermal absorption process, and is divided into six well organized sections. Written by internationally recognized experts in the field, this Second Edition is a complete revised and updated text, covering the wide range of methods used to assess skin ab
Book Synopsis Methods for Skin Absorption by : Barbara W. Kemppainen
Download or read book Methods for Skin Absorption written by Barbara W. Kemppainen and published by CRC Press. This book was released on 1990-06-13 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date volume describes the wide variety of available methods concerning percutaneous absorption of drugs and toxins. It discusses in detail the advantages and disadvantages of each method. This unique publication provides a clear, systematic presentation of each aspect which must be considered when designing and performing skin penetration experiments and when interpreting results. It includes specific information regarding necessary supplies and equipment, along with commercial sources for these items. This state-of-the-art book is an ideal instructional manual for investigators uninitiated in performing percutaneous absorption and metabolism studies. Those involved with investigative dermatology, dermatological research, toxicology, and pharmacology will find this reference interesting and indispensable.
Book Synopsis In Vitro Percutaneous Absorption; Principles, Fundamentals, and Applications by : RL. Bronaugh
Download or read book In Vitro Percutaneous Absorption; Principles, Fundamentals, and Applications written by RL. Bronaugh and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 427: Skin Absorption: In Vivo Method by : OECD
Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 427: Skin Absorption: In Vivo Method written by OECD and published by OECD Publishing. This book was released on 2004-11-23 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: The in vivo percutaneous absorption study set out in this Test Guideline provides the linkage necessary to extrapolate from oral studies when making safety assessments following dermal exposure. The in vivo method, described in this guideline ...
Book Synopsis Topical Drug Bioavailability, Bioequivalence, and Penetration by : Vinod P. Shah
Download or read book Topical Drug Bioavailability, Bioequivalence, and Penetration written by Vinod P. Shah and published by Springer. This book was released on 2015-01-30 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative volume explores advances in the techniques used to measure percutaneous penetration of drugs and chemicals to assess bioavailability and bioequivalence and discusses how they have been used in clinical and scientific investigations. Seven comprehensive sections examine topics including in vitro drug release, topical drugs products, clinical studies, and guidelines and workshop reports, among others. The book also describes how targeted transdermal drug delivery and more sophisticated mathematical modelling can aid in understanding the bioavailability of transdermal drugs. The first edition of this book was an important reference guide for researchers working to define the effectiveness and safety of drugs and chemicals that penetrated the skin. This second edition contains cutting-edge advances in the field and is a key resource to those seeking to define the bioavailability and bioequivalence of percutaneously active compounds to improve scientific and clinical investigation and regulation.
Download or read book Dermal Absorption written by J. Kielhorn and published by World Health Organization. This book was released on 2006 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction and definitions -- Skin structure and function -- Skin transport mechanisms and theoretical concepts -- Metabolism in the skin -- In vitro tests for dermal absorption -- In vivo tests for dermal absorption -- Comparative studies -- Data collections -- Estimation/prediction of dermal penetration -- Use of dermal penetration studies in risk assessment -- Controversial topics in the assessment of dermal absorption -- Conclusions and recommendations.
Book Synopsis Predictive Methods in Percutaneous Absorption by : Gary P. Moss
Download or read book Predictive Methods in Percutaneous Absorption written by Gary P. Moss and published by Springer. This book was released on 2015-07-01 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book sheds new light on the development and use of quantitative models to describe the process of skin permeation. It critically reviews the development of quantitative predictive models of skin absorption and discusses key recommendations for model development. Topics presented include an introduction to skin physiology; the underlying theories of skin absorption; the physical laboratory-based processes used to generate skin absorption data, which is in turn used to construct mathematical models describing the skin permeation process; algorithms of skin permeability including quantitative structure-activity (or permeability) relationships (QSARs or QSPRs); relationships between permeability and molecular properties; the development of formulation-focused approaches to models of skin permeability prediction; the use of artificial membranes, e.g. polydimethylsiloxane as alternatives to mammalian skin; and lastly, the use of novel Machine Learning methods in developing the next generation of predictive skin permeability models. The book will be of interest to all researchers in academia and industry working in pharmaceutical discovery and development, as well as readers from the field of occupational exposure and risk assessment, especially those whose work involves agrochemicals, bulk chemicals and cosmetics.
Book Synopsis Maintenance of Skin Viability During in Vitro Percutaneous Absorption/metabolism Studies by : Steven W. Collier
Download or read book Maintenance of Skin Viability During in Vitro Percutaneous Absorption/metabolism Studies written by Steven W. Collier and published by . This book was released on 1988 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Percutaneous Absorption of UV Filters Contained in Sunscreen Cosmetic Products by : Zacarías León González
Download or read book Percutaneous Absorption of UV Filters Contained in Sunscreen Cosmetic Products written by Zacarías León González and published by Springer. This book was released on 2016-08-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Zacarías León's thesis describes the development and validation of analytical methods to estimate the processes set in motion by percutaneous absorption of UV filters in sunscreen cosmetic products. León describes these methods in both in vitro and non-invasive in vivo methodologies. Currently dermatologists recommend the use of sunscreen products not only under conditions of extreme exposure to the sun but also in daily situations. However the chemical compounds in these products contain may lead to undesired processes and cause induced toxicity, estrogenic effects and endocrine activity. León establishes methods to investigate these effects and provides valuable information on the undesired side effects associated with the use of UV filters found in sunscreen products. The work in this thesis has led to a number of publications in renowned analytical chemistry journals.
Book Synopsis Percutaneous Absorption by : Robert L. Bronaugh
Download or read book Percutaneous Absorption written by Robert L. Bronaugh and published by . This book was released on 1989 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Percutaneous Absorption written by and published by . This book was released on 1993 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fragrances written by Peter J. Frosch and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aromas are an integral part of our civilised society. They are not only used in fine perfumes, but also in numerous other articles with which we have daily contact. Another new development has been the agricultural use of aromas as a "biological weapon" to combat insects and other pests. In the field of dermatology, aromas are today among the most frequent sensitizers and may trigger allergic contact eczemas. This volume presents numerous aspects of the topic for the first time in comprehensive form. In an introduction, the chemistry of frequently used aroma components is described, together with the art of perfume composition that has been refined over the centuries. In a chapter on neuropharmacology, the mechanisms of scent recognition are described in detail.
