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Author : E. Richard Stiehm
Publisher : Ardent Media
ISBN 13 : 9780842271998
Total Pages : 238 pages
Book Rating : 4.2/5 (719 download)
Download or read book Immunotherapy: Cellular Transplants & Immunostimulation written by E. Richard Stiehm and published by Ardent Media. This book was released on 1974 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : L. Chedid
Publisher : Springer Science & Business Media
ISBN 13 : 3642678092
Total Pages : 238 pages
Book Rating : 4.6/5 (426 download)
Download or read book Immunostimulation written by L. Chedid and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of specifically acquired immunity which followed the major contributions of Louis Pasteur completely over-shadowed the first studies of the host's natural resistance. Later, the exquisite sensitivity and precision of antigen-antibody reactions made the study of immunochemistry much more attractive than the rather primitive and ambiguous field of non-specific immunity. Neverthe less, during the last three decades, a considerable body of informa tion was developed and also means by which natural resistance could be enhanced or depressed by exogenous agents such as lipopolysaccharides or BCG. An important advance was the chemical recognition of the biologically active components of these agents which in turn allowed the synthesis or" analogues. More recently, endogenous host products which can play a role in nonspecific immunity, such as thymic hormones, have also been identified, produced and used both experimentally and clinically. It therefore seemed worthwile to Drs. Miescher and Mueller-Eberhard to devote two volumes of Seminars in Immunopathology to the topic of Immunostimuhltion. Because of the good response obtai ned from readers, Springer Verlag decided to issue a hard cover book and asked their guest editor to make a preface. Prefaces, although they are found in the opening pages, are always written after the first issue has been completed.
Author : E. Raz
Publisher : Springer Science & Business Media
ISBN 13 : 9783540677499
Total Pages : 202 pages
Book Rating : 4.6/5 (774 download)
Download or read book Immunostimulatory DNA Sequences written by E. Raz and published by Springer Science & Business Media. This book was released on 2001 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a product of a collaborative effort and attempts to provide a wide and up-to-date coverage of information regarding the biology and on the potential application of immunostimulatory DNA. ISS hold great promise for influencing the immune response and the authors anticipate that the high efficacy and low toxicity observed in animal models will translate into success in a variety of human clinical applications.
Author : Shayne Cox Gad
Publisher : John Wiley & Sons
ISBN 13 : 0470249048
Total Pages : 1075 pages
Book Rating : 4.4/5 (72 download)
Download or read book Preclinical Development Handbook written by Shayne Cox Gad and published by John Wiley & Sons. This book was released on 2008-03-21 with total page 1075 pages. Available in PDF, EPUB and Kindle. Book excerpt: A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use resource discusses all the issues that need consideration and provides detailed instructions for current methods and techniques. Each chapter was written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach. The editor, with more than thirty years' experience working with pharmaceutical and biotechnology companies, carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear. Among the key topics covered are: * In vitro mammalian cytogenetics tests * Phototoxicity * Carcinogenicity studies * The pharmacogenomics of personalized medicine * Bridging studies * Toxicogenomics and toxicoproteomics Each chapter offers a full exploration of problems that may be encountered and their solutions. The authors also set forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage. This is a hands-on guide for pharmaceutical scientists involved in preclinical testing,enabling them to perform and document preclinical safety tests to meet all FDA requirements before clinical trials may begin.
Author : Shayne Cox Gad
Publisher : John Wiley & Sons
ISBN 13 : 1119755859
Total Pages : 996 pages
Book Rating : 4.1/5 (197 download)
Download or read book Drug Safety Evaluation written by Shayne Cox Gad and published by John Wiley & Sons. This book was released on 2023-01-12 with total page 996 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Safety Evluation Comprehensive and practical guide presenting a roadmap for safety assessment as an integral part of the development of drugs and therapeutics This fourth edition of Drug Safety Evaluation maintains the central objective of presenting an all-inclusive practical guide for those who are responsible for ensuring the safety of drugs and biologics to patients, healthcare providers, those involved in the manufacture of medicinal products, and all those who need to understand how the safety of these products is evaluated and shepherding valuable candidates to market. Individual chapters address specific approaches to evaluation hazards, including problems that are encountered and their solutions. Also covered are the scientific and philosophical bases for evaluation of specific concerns (e.g., carcinogenicity, development toxicity, etc.) to provide both understanding and guidance for approaching the new problems that have come to face both our society and the new challenges they brought. The many changes in regulatory requirements, pharmaceutical development, technology, and the effects of Covid on our society and science have required both extensive revision to every chapter and the addition of four new chapters. Specific sample topics covered in Drug Safety Evaluation include: The drug development process and the global pharmaceutical marketplace and regulation of human pharmaceutical safety Sources of information for consideration in study and program design and in safety evaluation Electronic records, reporting and submission, screens in safety and hazard assessment, and formulations, routes, and dosage regimens Mechanisms and endpoints of drug toxicity, pilot toxicity testing in drug safety evaluation, and repeat dose toxicity Genotoxicity, QSAR tools for drug safety, toxicogenomics, nonrodent animal studies, and developmental and reproductive toxicity testing An appendix which provides an up to date guide to CROs for conducting studies Drug Safety Evaluation was written specifically for the pharmaceutical and biotechnology industries, including scientists, consultants, and academics, to show a utilitarian yet scientifically valid path to the everyday challenges of safety evaluation and the problem solving that is required in drug discovery and development.
Author : J. Robin Harris
Publisher : Springer Science & Business Media
ISBN 13 : 9780306431388
Total Pages : 490 pages
Book Rating : 4.4/5 (313 download)
Download or read book Virally Infected Cells written by J. Robin Harris and published by Springer Science & Business Media. This book was released on 1989-07-31 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular virology has made tremendous advances in the past decade due to the availability and application of new immunological techniques together with the vast range of biochemical techniques and the continued impact of transmission electron microscopy. The chapters contained in this volume provide significant coverage of the subject of cellular virology as a whole. Considerable overall emphasis is placed upon the membrane biochemistry of viral proteins and glycoproteins within the infected cell. In the opening chapter Edouard Kurstak and his colleagues provide a useful survey on the detection of viral antigens and antibodies by immunoassays. This chapter, with its emphasis on the important role of immunology in present-day virology, sets the scene for the volume. Following this is an exciting presentation from Stefan Hoglund and his colleagues on ISCOMs and immunostimulation with viral antigens. This unique approach is already proving to be of value, particularly in animal virology. A somewhat pharmacological diversion appears in Chapter 3, by Kazukiyo Onodera and his colleagues, in which the biological activity of the damavaricin C derivatives is discussed. This chapter provides a link between the biochemical and the chemotherapeutic approach in cellular virology. Yet another specialist area is covered in Chapter 4 by Otto Schmidt and hnke Schuchmann-Feddersen, who discuss the role of virus-like particles in para site-host interactions of insects. Contributing a strong biomedical emphasis to the volume is the provocative chapter by Abraham Karpas on human leukemia and retroviruses.
Author : Bianca Castiglioni
Publisher : MDPI
ISBN 13 : 3036508961
Total Pages : 188 pages
Book Rating : 4.0/5 (365 download)
Download or read book Genetics of Animal Health and Disease in Livestock written by Bianca Castiglioni and published by MDPI. This book was released on 2021-06-02 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wood surface attributes can be established by examining its several different physical or chemical properties. Differences in the wood surfaces occur between the manufacturing and post-treatment processes as well. Understanding how their unique anisotropic molecular organization, chemical linkages, branching, and other molecular features govern micro- and macroscale accessibility is essential for coating and complex modification processes. It is therefore important for scientific as well as practical reasons to qualify and quantify the effects of wood surface treatments and modifications. Challenges still exist to fully understanding the effect of the numerous applied chemicals and the wide range of treatment processes on wood surfaces.
Author : Mary Mehrnoosh Eshaghian-Wilner
Publisher : John Wiley & Sons
ISBN 13 : 1118993616
Total Pages : 664 pages
Book Rating : 4.1/5 (189 download)
Download or read book Wireless Computing in Medicine written by Mary Mehrnoosh Eshaghian-Wilner and published by John Wiley & Sons. This book was released on 2016-06-09 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a comprehensive overview of wireless computing in medicine, with technological, medical, and legal advances This book brings together the latest work of leading scientists in the disciplines of Computing, Medicine, and Law, in the field of Wireless Health. The book is organized into three main sections. The first section discusses the use of distributed computing in medicine. It concentrates on methods for treating chronic diseases and cognitive disabilities like Alzheimer’s, Autism, etc. It also discusses how to improve portability and accuracy of monitoring instruments and reduce the redundancy of data. It emphasizes the privacy and security of using such devices. The role of mobile sensing, wireless power and Markov decision process in distributed computing is also examined. The second section covers nanomedicine and discusses how the drug delivery strategies for chronic diseases can be efficiently improved by Nanotechnology enabled materials and devices such as MENs and Nanorobots. The authors will also explain how to use DNA computation in medicine, model brain disorders and detect bio-markers using nanotechnology. The third section will focus on the legal and privacy issues, and how to implement these technologies in a way that is a safe and ethical. Defines the technologies of distributed wireless health, from software that runs cloud computing data centers, to the technologies that allow new sensors to work Explains the applications of nanotechnologies to prevent, diagnose and cure disease Includes case studies on how the technologies covered in the book are being implemented in the medical field, through both the creation of new medical applications and their integration into current systems Discusses pervasive computing’s organizational benefits to hospitals and health care organizations, and their ethical and legal challenges Wireless Computing in Medicine: From Nano to Cloud with Its Ethical and Legal Implications is written as a reference for computer engineers working in wireless computing, as well as medical and legal professionals. The book will also serve students in the fields of advanced computing, nanomedicine, health informatics, and technology law.
Author : Jacques Descotes
Publisher : CRC Press
ISBN 13 : 0203362543
Total Pages : 196 pages
Book Rating : 4.2/5 (33 download)
Download or read book Introduction To Immunotoxicology written by Jacques Descotes and published by CRC Press. This book was released on 2003-09-02 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a concise and comprehensive introduction to key immunotoxicological issues for all those interested in, but with no prior knowledge of, this area of toxicology. The first section explores the health consequences of immunotoxicity, namely the adverse effects related to chemically-induced immunosuppression and immunostimulation, hypersensitivity reactions and autoimmune diseases, with an overview of major immunotoxicants. The second part describes the latest methods used to detect and evaluate, preclinically and clinically, the unexpected immunotoxic effects of xenobiotics. Trends in implementing strategies and recent changes to the regulatory aspects are also considered. The third section examines possible future developments, including In Vitro methods, biomarkers of immunotixicity and risk assessment.
Author : R. Fuller
Publisher : Springer Science & Business Media
ISBN 13 : 9401727686
Total Pages : 276 pages
Book Rating : 4.4/5 (17 download)
Download or read book Probiotics 3 written by R. Fuller and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The way in which probiotics work is still not clearly defined, but it is becoming more and more apparent that immune stimulation is an important feature in some of the observed effects. In the previous two books in this series the scientific basis and the practical applications were considered. It seemed that the immunogenic potential of probiotics merited a book of its own with experts from all over the world covering the general effect of the gut microflora on immunity as well as the particular response that pro biotic microorganisms generate. The importance of immune stimulation by probiotic organisms cannot be overemphasised. It opens up the technique for use, not only as a treatment for intestinal diseases, but also as a treatment that could be effective against infections outside the gastrointestinal tract. This book considers how the body reacts to the presence of orally administered microorganisms (normally lactic acid bacteria). The responses may be in the form of antibodies (lgA, IgG, IgM), cytokines, killer cells or macrophage activity. Do these responses result in antagonism of the stimulating bacteria, do they affect the composition of the indigenous gut microflora and are they sufficienty strong to kill bacterial pathogens or tumour cells? Where we have answers these will be reported and discussed; where there are no answers there will be speculation and prediction.
Author : Stefan Bauer
Publisher : Springer Science & Business Media
ISBN 13 : 3540721673
Total Pages : 243 pages
Book Rating : 4.5/5 (47 download)
Download or read book Toll-Like Receptors (TLRs) and Innate Immunity written by Stefan Bauer and published by Springer Science & Business Media. This book was released on 2007-12-11 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.
Author : John Henry Van Uden
Publisher :
ISBN 13 :
Total Pages : 308 pages
Book Rating : 4.:/5 (318 download)
Download or read book Immunostimulatory DNA and the Host-pathogen Relationship written by John Henry Van Uden and published by . This book was released on 2001 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Hailing Jin
Publisher : Frontiers Media SA
ISBN 13 : 2889714020
Total Pages : 151 pages
Book Rating : 4.8/5 (897 download)
Download or read book RNAi Based Pesticides written by Hailing Jin and published by Frontiers Media SA. This book was released on 2021-09-29 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Natural Standard
Publisher : Elsevier Health Sciences
ISBN 13 : 0323291457
Total Pages : 896 pages
Book Rating : 4.3/5 (232 download)
Download or read book Natural Standard Herb & Supplement Guide - E-Book written by Natural Standard and published by Elsevier Health Sciences. This book was released on 2016-07-28 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering 400 herbs and supplements, Natural Standard Herb & Supplement Guide: An Evidence-Based Reference provides the high-quality, up-to-date, unbiased information you need to advise your patients. No other book can match its expertise and attention to evidence! Each monograph is concise and easy to read, and includes uses, dosage information, safety considerations, and interactions with drugs and other herbs and supplements. At-a-glance research summaries and an alphabetical organization allow for quick lookup in busy settings! Monographs for the 400 most commonly used and prescribed herbs and supplements — such as arnica, ginseng, lavender, glucosamine, and blue cohosh — provide the information you need for effective clinical decision-making. A unique, evidence-based A-F grading scale evaluates the efficacy of each herb and supplement. Unique! Rating scales show at a glance the quality of available evidence. Updates are peer-reviewed, and include new scientific evidence, dosage recommendations, and more. Dosing information includes dosages for adults and children, and methods for administering. Coverage of allergies, side effects/warnings, and pregnancy/breast-feeding promotes safety by indicating when specific herbs and supplements should not be used, or when caution is required. A review of evidence includes detailed explanations of clinical trials cited and conclusions drawn, especially as they relate to specific diseases and conditions. Evidence tables summarize clinical trial data and provide a quick reference for clinical decision-making. Unique! Cross-referencing by condition and scientific evidence grade provides a convenient decision support tool, making it easy to find the herbs and supplements that may be used for the treatment of particular conditions.
Author :
Publisher : IICA Biblioteca Venezuela
ISBN 13 :
Total Pages : 334 pages
Book Rating : 4./5 ( download)
Download or read book Bibliografía sobre laboratorios de salud animal written by and published by IICA Biblioteca Venezuela. This book was released on with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Patrick Arbuthnot
Publisher : Academic Press
ISBN 13 : 0124114520
Total Pages : 392 pages
Book Rating : 4.1/5 (241 download)
Download or read book Gene Therapy for Viral Infections written by Patrick Arbuthnot and published by Academic Press. This book was released on 2015-06-01 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options. Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene editing, viral gene therapy vectors, and non-viral vectors. Subsequent sections include detailed coverage of the developing use of gene therapy for the treatment of specific infections, the principles of rational design of antivirals, and the hurdles that currently face the further advancement of gene therapy technology. Provides coverage of gene therapy for a variety of infections, including HBV, HCV, HIV, hemorrhagic fever viruses, and respiratory and other viral infections Bridges the gap between the basic science and the important medical applications of this technology Features a broad approach to the topic, including an essential overview and the applications of gene therapy, synthetic RNA, and other antiviral strategies that involve nucleic acid engineering Presents perspectives on the future use of nucleic acids as a novel class of antiviral drugs Arms the reader with the cutting-edge information needed to stay abreast of this developing field
Author :
Publisher :
ISBN 13 :
Total Pages : 124 pages
Book Rating : 4.:/5 (3 download)
Download or read book Cancer Treatment Reports written by and published by . This book was released on 1987 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
