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Immunopathogenesis Of Rheumatoid Arthritis
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Book Synopsis New Developments in the Pathogenesis of Rheumatoid Arthritis by : Lazaros Sakkas
Download or read book New Developments in the Pathogenesis of Rheumatoid Arthritis written by Lazaros Sakkas and published by BoD – Books on Demand. This book was released on 2017-02-22 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pathogenesis of rheumatoid arthritis (RA) is incompletely understood. HLA class II alleles and T cells have been implicated for many years. The discovery of anticitrullinated peptide antibodies (ACPAs), along with the effectiveness of biological treatments targeting cytokines, such as TNF-?, IL-6, and also T cells and B cells, reinforced the pathogenetic role of the respective factors. ACPAs, induced by cigarette smoking and periodontitis in individuals with HLA-DRB1 shared epitope, appear to be autoantigens that initiate the inflammatory immune response in RA. MicroRNAs, part of epigenetic mechanisms, which also include DNA methylation, and histone modification, as well as microbiota, the composition of microbes in body cavities, also appear to influence arthritis and are discussed in this book.
Book Synopsis Immunopathogenesis of Rheumatoid Arthritis by : Gabriel Stavros Panayi
Download or read book Immunopathogenesis of Rheumatoid Arthritis written by Gabriel Stavros Panayi and published by . This book was released on 1979 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunologie / Polyarthritis.
Book Synopsis Immunopathogenetic Mechanisms of Arthritis by : J.A. Goodacre
Download or read book Immunopathogenetic Mechanisms of Arthritis written by J.A. Goodacre and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fundamental problem facing scientists and clinicians in Rheumatology is that so little is known about the biology of joints. It is our view that a real interface between basic and clinical science offers the best chance of gaining a better understanding of arthritis and in this book we aim to provide a basis for such an interface. Each chapter provides a lucid account of the current literature, reflecting the eminence of each author in their own field. The contributors offer a variety of modern approaches to the study of inflammatory joint disease, illustrating some of the exciting opportunities for research which exist. We hope that those who share our view find these pages informative and stimulating. University of Newcastle upon Tyne, 1987. JOHN A. GOODACRE W. CARSON DICK ix 1 • Polymorphonuclear leukocytes In acute inflammation O. T. G. JONES and A. R. CROSS INTRODUCTION The nonnal function of the professional phagocytes - polymorphonuclear leukocytes (PMN), monocytes, macrophages and eosinophils - is to protect the individual from microbial infection by seeking out and destroying the invading microbes. In order to perform this function effectively the phagocyte must move towards sites of infection, recognize, phagocytose, kill and digest the microbe and, if necessary, recruit other cells to assist. These phagocytic cells possess a membrane-bound enzyme system which can be activated to produce toxic oxygen radicals in response to a wide variety of stimuli.
Book Synopsis Studies Concerning the Immunopathogenesis of Rheumatoid Arthritis with Particular Reference to Immune Complexes and Lymphocyte Function by : John Highton
Download or read book Studies Concerning the Immunopathogenesis of Rheumatoid Arthritis with Particular Reference to Immune Complexes and Lymphocyte Function written by John Highton and published by . This book was released on 1983 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis New Developments in the Pathogenesis of Rheumatoid Arthritis by :
Download or read book New Developments in the Pathogenesis of Rheumatoid Arthritis written by and published by . This book was released on 19?? with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunopathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus by : Nathan J. Zvaifler
Download or read book Immunopathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus written by Nathan J. Zvaifler and published by . This book was released on 1974 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Research of Pathogenesis and Novel Therapeutics in Arthritis by : Chih-Hsin Tang
Download or read book Research of Pathogenesis and Novel Therapeutics in Arthritis written by Chih-Hsin Tang and published by MDPI. This book was released on 2019-06-04 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arthritis has a high prevalence globally and includes over 100 different types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. The exact etiology of arthritis remains unclear and no cure exists. Anti-inflammatory drugs are commonly used in the treatment of arthritis but are associated with significant side effects. Novel modes of therapy and additional prognostic biomarkers are urgently needed for arthritis patients. This book summarizes and discusses the global picture of the current understanding of arthritis.
Book Synopsis T Cells in Arthritis by : P. Miossec
Download or read book T Cells in Arthritis written by P. Miossec and published by Springer Science & Business Media. This book was released on 1998-07-21 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rheumatoid arthritis (RA) is the most common and most severe form of inflammatory arthritis. The pathogenesis of RA has been the subject of intense research for several decades. The prevailing hypotheses have changed over the years, and have attempted to incorporate the most recent data. Although T cells represent an important component of the cells which infiltrate the joint synovium, their contribution at a late stage of the disease remains a matter of debate. The goal of this book is to outline the major arguments and data suggesting that T cells may, or may not, be central players in the pathogenesis of chronic RA. While each of the editors and authors has his/her own bias (as will be clear by reading the respective chapters), our hope is that the readers will enjoy a complete and balanced view of the critical questions and experiments. This is not just an intellectual exercise since the direction of future therapeutic interventions depends heavily on how one interprets the pathogenesis of RA and the contribution of T cells.
Book Synopsis Immunopathogenesis and Immune-based Therapy for Selected Autoimmune Disorders by : Mourad Aribi
Download or read book Immunopathogenesis and Immune-based Therapy for Selected Autoimmune Disorders written by Mourad Aribi and published by BoD – Books on Demand. This book was released on 2017-03-22 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book Immunopathogenesis and Immune-Based Therapy for Selected Autoimmune Disorders is a synthesis work that discusses two main aspects of autoimmunity: Immunopathogenesis and therapeutic approaches essentially based on the immunotherapies. This book deals with different topics on a number of autoimmune disorders, including type 1 diabetes, autoimmune cardiomyopathy, autoimmunity of gastrointestinal tract, systemic sclerosis, and myasthenia gravis. This book will be useful to clinicians, biologists, researchers, teachers, and students who are interested in immunology and immunopathology.
Book Synopsis Early Rheumatoid Arthritis by : Paul Emery
Download or read book Early Rheumatoid Arthritis written by Paul Emery and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue covers the latest developments in the understanding of rheumatoid arthritis at the early stage. Treatments such as with newer biologic agents and conventional disease-modifying antirheumatic drugs are reviewed. Also included are articles on imaging modalities as a means of identifying those in the early stages and monitoring response to treatment.
Book Synopsis Rheumatoid Arthritis by : Josef S. Smolen
Download or read book Rheumatoid Arthritis written by Josef S. Smolen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many advances have occurred in the last 5 years especially in understanding genetic susceptibility factors, the role of immune response in chronic arthritis and the relationship between cellular processes that underlie inflammation and tissue damage. All these are dealt with in depth in the individual contributions. Genetics studies included illustrate how studies of HLA genes and genes controlling the autoantibody repertoire may be involved. Environmental factors are believed to be important and studies both in humans and in experimental models on the role of viral and bacterial agents are covered. The fascinating relationship between microbes, dysregulated immune responses and oncogenes are also examined. Since autoimmunity is the key aspect of the immunological response in rheumatoid arthritis, the role of antigens is re-examined as is the part played by immune T and B cells. New areas of clinical application of basic science is well presented in this book, forexample, in examining how markers of cartilage destruction may become important in monitoring disease activity. A chapter reviewing possible future novel therapies is included.
Download or read book Essentials of Immune Response written by and published by . This book was released on 1984 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Resolution of Inflammation by : Adriano Rossi
Download or read book The Resolution of Inflammation written by Adriano Rossi and published by Springer Science & Business Media. This book was released on 2008-03-17 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.
Book Synopsis Early Treatment and Immunopathogenesis of Patients with Recent-onset Rheumatoid Arthritis by : Leroy Rainey Lard
Download or read book Early Treatment and Immunopathogenesis of Patients with Recent-onset Rheumatoid Arthritis written by Leroy Rainey Lard and published by . This book was released on 2003 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Role of GLK in T Cells in the Immunopathogenesis of Rheumatoid Arthritis by : Yi-Ming Chen
Download or read book The Role of GLK in T Cells in the Immunopathogenesis of Rheumatoid Arthritis written by Yi-Ming Chen and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Atlas of Rheumatoid Arthritis by : Paul Emery
Download or read book Atlas of Rheumatoid Arthritis written by Paul Emery and published by Springer. This book was released on 2015-06-09 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atlas of Rheumatoid Arthritis is a high-quality educational initiative, written by leaders in the field of rheumatology, containing a collection of approximately 150 relevant images, with extended descriptive captions and a comprehensive bibliography. The Atlas of Rheumatoid Arthritis will provide clinicians with a visual guide to rheumatoid arthritis, focusing on assessment, diagnosis and treatment, including newer research into the signalling pathways involved in the pathogenesis of RA, before focusing on the treatment of RA. Rheumatoid arthritis (RA) is the most common and most serious of the inflammatory arthritic disorders, and it dominates clinical rheumatological practice. Effective, early treatment is vital as this can slow the course of the disease and reduce joint damage. RA is usually treated using disease-modifying anti-rheumatic drugs (DMARDs), most commonly methotrexate. The newest treatments target the disease-causing immune elements specifically and directly.
Book Synopsis Mosaic of Autoimmunity by : Carlo Perricone
Download or read book Mosaic of Autoimmunity written by Carlo Perricone and published by Academic Press. This book was released on 2019-02-15 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis. Highlights the concept of the mosaic of autoimmune manifestations Includes new visions on unsuspected molecules Provides updated knowledge to physicians helping patients with autoimmune diseases Presents thorough, up-to-date information on specific diseases, along with clinical applications
