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Immunity And Immunopathogenesis To Herpesviruses
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Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Book Synopsis Janeway's Immunobiology by : Kenneth Murphy
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Book Synopsis Cell Biology of Herpes Viruses by : Klaus Osterrieder
Download or read book Cell Biology of Herpes Viruses written by Klaus Osterrieder and published by Springer. This book was released on 2017-05-20 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Herpes viruses are widely distributed in nature, causing disease in organisms as diverse as bivalves and primates, including humans. Each virus appears to have established a long-standing relationship with its host, and the viruses have the ability to manipulate and control the metabolism of host cells, as well as innate and adaptive antiviral immune responses. Herpes viruses maintain themselves within hosts in a latent state resulting in virus persistence for years – usually for the life span of the hosts. Herpes viruses comprise a large number of pathogens with diverse cellular targets and biological consequences of infection. What they have in common is their structure and the fact that they establish a dormant (latent) infection in their hosts that usually persists for life. The reviews here will highlight the general principles of herpes virus infection, with equal attention to overall principle and important difference. Also, the cell type- and life-style dependent differences in the establishment and maintenance of virus persistence will be covered.
Book Synopsis The Third Component of Complement by : John D. Lambris
Download or read book The Third Component of Complement written by John D. Lambris and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third component of complement, C3, is one of the most versatile proteins and an important participant in immune surveillance and immune response pathways. Its multifunctio nality is based on its ability to interact specifically with multiple serum complement proteins, cell surface receptors, and mem brant;-associated regulatory proteins. One of its most intriguing strategies of interaction with cell surfaces is the covalent binding of activated C3 through the internal thioester. The field has expanded over the past 10 years and a wealth of information has accumulated. C3 from various species and many of the human C3 binding proteins have been cloned and expressed. Numerous cellular responses mediated by the diffe rent fragments of C3 have been described. The findings that C3 interacts in a ligand-receptor-like fashion with proteins of nonself origin such as the gC of herpes simplex virus, a 70-kDa protein from Candida albicans, proteins from Epstein-Barr virus, etc. has opened a new field of investigation. The papers assembled in this volume summarize the wealth of data on the various aspects of the C3 interactions; together they bring to the reader new information on the chemistry, molecular gene tics, biology, and pathophysiology of C3 and C3-binding proteins. Emphasis is given to structural features as they relate to functions. Spring 1989 JOHN D. LAMBRIS, HANS J. MULLER-EBERHARD Table of Contents J. E. VOLANAKIS: Participation of C3 and Its Ligands in Complement Activation . . . . . . . . . . . 1 S. R. BARNUM, G. FEY, and B. F. TACK: Biosynthesis and Genetics of C3 . . . . . . . . . . . . .
Book Synopsis Herpes Simplex Virus by : Barry T. Rouse
Download or read book Herpes Simplex Virus written by Barry T. Rouse and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although upstaged by the tragic appearance of the human immunodeficiency virus, herpes simplex viruses (HSV) types 1 and 2 continue to be major human pathogens against which we lack acceptable vaccines or other means of immunological control. The virus is large and complex, coding for 70 or more proteins. Although many mysteries remain to be unraveled, our knowledge base regarding genomic organization, gene expression and regulation, pathogenesis, and immune recog nition of component parts is quite considerable. Indeed, meet ings devoted entirely to herpesviruses are conspicuous by their frequency and excellent, yet sometimes exclusive, attendance. The purpose of this volume is to compile in a single book a series of reviews by leading investigators that deal with various aspects of virus-host interactions and which hopefully will pro vide clues as to how to best manage HSV from an immunobio logical perspective. Ultimately, one anticipates that a full under standing of virus-host interaction will lead to strategies useful for the prevention and control of HSV. The state of current progress with conventional vaccines is presented, as is a chapter on intracellular immunization. This latter novel approach to virus infections comes at approximately the bicentenary of Jenner's introduction of a successful conventional immunization strategy.
Book Synopsis Immunity and Immunopathogenesis to Herpesviruses by : Susmit Suvas
Download or read book Immunity and Immunopathogenesis to Herpesviruses written by Susmit Suvas and published by Frontiers Media SA. This book was released on 2020-01-20 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Herpesviruses are a large group of double-stranded DNA viruses, which have evolved strategies to persist and disseminate widely throughout the human population. Unlike RNA viruses which have the ability to alter their antigenic expression profile to evade host immune responses, herpesviruses can establish life-long latency in the infected host. Herpesviruses are divided into alpha, beta and gamma herpesviruses sub-families. The human members of the alpha-herpesvirinae subfamily is comprised of herpes simplex virus-1 and 2 (HSV-1 and HSV-2) and of varicella-zoster virus (VZV). These viruses are considered neurotropic, as they can (i) infect nerve endings; (ii) traffic via neuronal axons and (iii) establish latency in neuronal nuclei. On the other hand, the members of the beta-herpesvirinae subfamily such as human cytomegalovirus (HCMV), human herpesviruses 6 and 7 (HHV-6 and HHV-7) are known to establish latent infections in immune cell types such as monocytes and T cells. Epstein-Barr Virus (EBV) is a member of gamma-herpesvirinae subfamily that establishes latency in B lymphocytes. Additionally, HHV-8 also known as Kaposi’s Sarcoma-Associated Herpes virus (KSHV) is a γ-herpes virus which establishes latency in monocytes, dendritic cells, B lymphocytes and endothelial cells of the host.
Book Synopsis Herpes Simplex Virus by : Adrian Mindel
Download or read book Herpes Simplex Virus written by Adrian Mindel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Herpes Simplex Virus is the fifth monograph to be published in the Bloomsbury Series of Clinical Science. It provides an authoritative review of the key issues related to this common clinical problem. The characteristics of the virus, its epidemiology and the diag nosis and management of the various forms of infection are all considered. Adrian Mindel is an international authority on this subject; he joined the Academic Department of Genito-urinary Medicine at the Middlesex Hospital in 1980 and has been actively involved in HSV research since that time. His major research interests include the epidemiology and treatment of genital herpes, the epidemi ology of neo-natal herpes and the many and varied features of HSV infections in immuno-compromised patients. The continuing aim of the Bloomsbury Series is to identify the growing areas of clinical research and relate these to current and future medical practice. In Herpes Simplex Virus such aspirations have been successfully achieved. London, May 1989 Jack Tinker Preface There has been considerable interest in herpes simplex viruses (HSV) over recent years. Amongst the many reasons for this are the introduction of safe and efficacious therapy, the recognition that HSV may cause life-threatening infections in neonates and immunocompromised patients, the observation that genital herpes is one of the commonest viral sexually transmitted diseases and the possible association of HSV with cervical cancer.
Download or read book Ocular Infection & Immunity written by and published by . This book was released on 1996 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Epstein Barr Virus Volume 2 by : Christian Münz
Download or read book Epstein Barr Virus Volume 2 written by Christian Münz and published by Springer. This book was released on 2015-10-01 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.
Book Synopsis Herpesvirus Latency by : Benedikt B. Kaufer
Download or read book Herpesvirus Latency written by Benedikt B. Kaufer and published by Frontiers Media SA. This book was released on 2020-09-14 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Book Synopsis Innate Immunity in Health and Disease by : Shailendra K. Saxena
Download or read book Innate Immunity in Health and Disease written by Shailendra K. Saxena and published by BoD – Books on Demand. This book was released on 2021-08-25 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book focuses on various aspects and properties of innate immunity, whose deep understanding is integral for safeguarding the human race from further loss of resources and economies due to innate immune response-mediated diseases. Throughout this book, we examine the individual mechanisms by which the innate immune response acts to protect the host from pathogenic infectious agents and other non-communicable diseases. Written by experts in the field, the volume discusses the significance of macrophages in infectious disease, tumor metabolism, and muscular disorders. Chapters cover such topics as the fate of differentiated macrophages and the molecular pathways that are important for the pathologic role of macrophages.
Download or read book Human Herpesvirus-6 written by and published by Elsevier. This book was released on 2006-07-04 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book presents a comprehensive review of Human Herpesvirus-6 (HHV-6) infects up to 90% of the world's population and can cause potentially life-threatening diseases. Clinicians typically do not search for HHV-6, and if they do, they will find only few laboratories providing the necessary diagnostic tests that can differentiate between active and latent infection. Adding to this problem is that scientists still disagree about whether serological or molecular assays will be the best diagnostic test, yet there is no disagreement about the inadequacy of many of the currently existing assays. Consequently, our knowledge of etiology and pathogenesis of HHV-6 associated diseases can only come from the combined efforts of clinicians, virologists, molecular biologists and pathologists. It is the prime task of this book to summarize the status quo of HHV-6 research and to further stimulate such a collaboration. It will be a valuable reference for both clinical and basic scientists including epidemiologists, virologists, practicing clinicians and infectiologists, pathologists and essentially all scientists entering the field of herpes virus research.
Book Synopsis Sexually Transmitted Diseases by : Lawrence R. Stanberry
Download or read book Sexually Transmitted Diseases written by Lawrence R. Stanberry and published by Academic Press. This book was released on 2012-11-19 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised and updated to reflect the changes of the past ten years, this book brings researchers, clinical investigators, clinicians, and students the most up-to-date research, findings and thought on sexual infection prevention, control and therapy available and serves as an essential reference for anyone working in the field. It provides comprehensive coverage of epidemiology, physiology and immunology, featuring general preventive strategies such as behavioural modification, barrier methods and topical microbicides.
Book Synopsis Stress Challenges and Immunity in Space by : Alexander Choukèr
Download or read book Stress Challenges and Immunity in Space written by Alexander Choukèr and published by Springer. This book was released on 2020-12-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Book Synopsis Virus-induced Immunopathology by : Morris Pollard
Download or read book Virus-induced Immunopathology written by Morris Pollard and published by . This book was released on 1968 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Alphaherpesviruses by : Ekaterina E Heldwein
Download or read book Alphaherpesviruses written by Ekaterina E Heldwein and published by . This book was released on 2020-07-24 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Autoimmune Diseases by : Noel R. Rose
Download or read book The Autoimmune Diseases written by Noel R. Rose and published by . This book was released on 1998 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Autoimmune Diseases comprehensively describes the clinical expressions of all known autoimmune diseases, as well as the experimental bases of autoimmunity and failure of tolerance. The scientific chapters include mechanisms of natural tolerance, the genetic basis of autoimmunity, the significance of apoptosis, the influence of cytokines, environmental influences, and experimental models. The clinical chapters cover autoimmune endocrine deficiencies, insulin-dependent diabetes, rheumatic disorders, neurological diseases, and diseases of the blood, skin, eye, kidney, and liver.
