Handbook of Research on Systems Biology Applications in Medicine

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Author :
Publisher : IGI Global
ISBN 13 : 1605660779
Total Pages : 982 pages
Book Rating : 4.6/5 (56 download)

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Book Synopsis Handbook of Research on Systems Biology Applications in Medicine by : Daskalaki, Andriani

Download or read book Handbook of Research on Systems Biology Applications in Medicine written by Daskalaki, Andriani and published by IGI Global. This book was released on 2008-11-30 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book highlights the use of systems approaches including genomic, cellular, proteomic, metabolomic, bioinformatics, molecular, and biochemical, to address fundamental questions in complex diseases like cancer diabetes but also in ageing"--Provided by publisher.

Moderate to Severe Psoriasis

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Author :
Publisher : CRC Press
ISBN 13 : 0429585985
Total Pages : 422 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Moderate to Severe Psoriasis by : John Koo

Download or read book Moderate to Severe Psoriasis written by John Koo and published by CRC Press. This book was released on 2014-03-18 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts in the dermatology field, this new fourth edition of Moderate-to-Severe Psoriasis discusses the current use of biologics and other pharmacologic and phototherapy treatments for moderate-to-severe psoriasis. Illustrated with high quality color figures, this standalone text emphasizes safe and effective treatments for the psoriasis

Advances in Psoriasis

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Author :
Publisher : Springer
ISBN 13 : 1447144325
Total Pages : 337 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Advances in Psoriasis by : Jeffrey M. Weinberg

Download or read book Advances in Psoriasis written by Jeffrey M. Weinberg and published by Springer. This book was released on 2014-08-28 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has become increasingly clear that psoriatic disease, both of the skin and joints, can be a significant diagnostic and therapeutic challenge for the physician and a debilitating illness for the patient. Genetic and immunologic advances have increased our understanding of the pathophysiology of psoriasis and psoriatic arthritis and there is a need for practically oriented evidence based references to describe the management options open to clinicians. The speed at which developments are occurring in the field also necessitates a novel approach to keeping up with these changes in practice and the need is for a reference that that be updated regularly as the subject requires. Psoriasis is an incredibly fast-moving discipline within dermatology. Guidelines, treatment options and management all change at incredible speed. There is a requirement to provide a comprehensive reference resource to provide practical, user friendly information for the dermatology profession to aid in the decision-making process. Psoriasis is a graphical subdiscipline of medicine and therefore this will have copious illustrations. As a fast moving discipline the emphasis must be on annual updates to ensure that readers are kept up to date on the important areas of development.

Comorbidity in Rheumatic Diseases

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Author :
Publisher : Springer
ISBN 13 : 3319599631
Total Pages : 439 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Comorbidity in Rheumatic Diseases by : Yasser El Miedany

Download or read book Comorbidity in Rheumatic Diseases written by Yasser El Miedany and published by Springer. This book was released on 2017-08-24 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores comorbidity in patients with rheumatic diseases and details both care and treatment options in standard clinical practice. Patients with rheumatic diseases are clinically complex, and the interplay of their disease activity with associated conditions may lead to increased morbidity and mortality. Recently there have been major advances in the management of rheumatic diseases, however, without addressing the potential comorbid conditions, including cardiovascular disease; pulmonary disease; and depression; outcomes remain poor. ​​​ With its 19 chapters, covering the management of major rheumatic diseases (e.g. rheumatoid arthritis, systemic lupus erythematosus , and osteoarthritis), potential comorbidities and treatment recommendations, as well as possible interactions between conditions; this book addresses the gap between textbook medicine and day to day patients' care. Authors also discuss the new hot issue of the comorbidity index, comparing the standard tools to the recently developed indices and how they can assist the rheumatologists in determining disease burden, prognosis, and comorbidity probability. This book is an ideal clinical guide and reference that enables rheumatologists, internal medicine physicians, and residents to address the full clinical expression of these rheumatic diseases with views towards prevention or early management of comorbid conditions.

Itch

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Publisher : CRC Press
ISBN 13 : 1466505435
Total Pages : 482 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Itch by : E. Carstens

Download or read book Itch written by E. Carstens and published by CRC Press. This book was released on 2014-02-25 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.

Skin

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Publisher : Univ of California Press
ISBN 13 : 0520275896
Total Pages : 288 pages
Book Rating : 4.5/5 (22 download)

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Book Synopsis Skin by : Nina G. Jablonski

Download or read book Skin written by Nina G. Jablonski and published by Univ of California Press. This book was released on 2013-02-20 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Our intimate connection with the world, skin protects us while advertising our health, our identity, and our individuality. This synthetic overview, written with a poetic touch and taking many intriguing side excursions, is a guidebook to the pliable covering that makes us who we are. This book celebrates the evolution of three unique attributes of human skin: its naked sweatiness, its distinctive sepia rainbow of colors, and its remarkable range of decorations. Author Jablonski begins with a look at skin's structure and functions and then tours its three-hundred-million-year evolution, delving into such topics as the importance of touch and how the skin reflects and affects emotions. She examines the modern human obsession with age-related changes in skin, especially wrinkles, then turns to skin as a canvas for self-expression, exploring our use of cosmetics, body paint, tattooing, and scarification"--Publisher's description.

Handbook of Mouse Mutations with Skin and Hair Abnormalities

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Author :
Publisher : CRC Press
ISBN 13 : 9780849383724
Total Pages : 582 pages
Book Rating : 4.3/5 (837 download)

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Book Synopsis Handbook of Mouse Mutations with Skin and Hair Abnormalities by : John P. Sundberg

Download or read book Handbook of Mouse Mutations with Skin and Hair Abnormalities written by John P. Sundberg and published by CRC Press. This book was released on 1994-05-19 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects. The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.

European Handbook of Dermatological Treatments

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Publisher : Springer Science & Business Media
ISBN 13 : 3662071312
Total Pages : 830 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis European Handbook of Dermatological Treatments by : Andreas D. Katsambas

Download or read book European Handbook of Dermatological Treatments written by Andreas D. Katsambas and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 830 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dermatology is a specialty in the field of medicine which constantly changes at a vast rate. Alongside technology, new drugs, methods and treatments are continuously developed for the treatment of all common skin diseases. The first edition of the European Handbook of Dermatological Treatments received an overwhelming response from dermatovenereologists all over Europe. Its easy-to-read format, which is also used for this 2nd edition, is aimed at helping the physician to obtain comprehensive information at a glance. The three main sections listed alphabetically define the different diseases, the drugs available and the various methods of treatment used in dermatological practice. Each chapter begins with a brief section of the aetiology and pathogenesis of the skin disease, and leads into the description of the clinical characteristics, the diagnosis and the differential diagnosis. Followed by a detailed discussion on treatment methods, alternative methods are covered as well. Each section ends with a reference list for further reading. This new edition provides an excellent update including the newest developments of drugs, methods and treatments in dermatological practice, maintaining the clear structure and well-proven format. It is a very comprehensive and practical guide and should not be missed by those treating patients with skin diseases.

Adverse Reactions to Biologics

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318061018
Total Pages : 120 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Adverse Reactions to Biologics by : L. Puig

Download or read book Adverse Reactions to Biologics written by L. Puig and published by Karger Medical and Scientific Publishers. This book was released on 2017-11-07 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: In many areas of medicine physicians still face the great challenge of finding therapies that will meet the patients’ needs. In dermatology the challenge has arisen on multiple fronts through advances in the understanding of the immunopathogenesis of many inflammatory and malignant cutaneous disorders. Breakthroughs, combined with significant developments in targeted immunotherapy, have resulted in improved outcomes as these newer therapies are being used for both approved indications and as off-label therapies for various chronic inflammatory skin disorders and many forms of skin cancer. In the expectation that by truly understanding the safety profile of these targeted therapies patients’ outcomes will be significantly improved, this book offers insights into topics such as adverse reactions, infectious complications and the perioperative use of biologics in psoriasis, immunogenicity of biologic therapies, paradoxical reactions, safety of biologics used to treat autoimmune bullous diseases and primary cutaneous lymphomas, adverse reactions and skin manifestations of therapies targeting melanoma and non-melanoma skin cancer and other neoplastic diseases. Eminent researchers with extensive clinical experience have contributed to this publication, providing an in-depth overview of the latest knowledge in this field.

Clinical and Basic Immunodermatology

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Publisher : Springer Science & Business Media
ISBN 13 : 1848001657
Total Pages : 812 pages
Book Rating : 4.8/5 (48 download)

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Book Synopsis Clinical and Basic Immunodermatology by : Anthony Gaspari

Download or read book Clinical and Basic Immunodermatology written by Anthony Gaspari and published by Springer Science & Business Media. This book was released on 2008-11-05 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dermatologists are being asked to understand the pathophysiology of a number of immune-mediated skin diseases. In addition, a number of new products have appeared on the market during the past decade which requires an understanding of the mechanisms of action of these drugs. Dermatologists, however, have no easily understood book to which they can refer to regarding the disease or the drug.

pH of the Skin: Issues and Challenges

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318063851
Total Pages : 214 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis pH of the Skin: Issues and Challenges by : C. Surber

Download or read book pH of the Skin: Issues and Challenges written by C. Surber and published by Karger Medical and Scientific Publishers. This book was released on 2018-08-21 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of expressing acidity as the negative logarithm of the hydrogen ion concentration was defined and termed pH in the beginning of the 20th century. The general usefulness of the pH concept for life science was recognized and later gained importance to analytical research. Reports on results of pH measurements from living skin established the term acid mantle - the skin's own protective shield that maintains a naturally acid pH. It is invisible to the eye but crucial to the overall wellbeing of skin. Chronic alkalization can throw this acid mantle out of balance, leading to inflammation, dermatitis, and atopic skin diseases. It is therefore no surprise, that skin pH shifts have been observed in various skin pathologies. It is also obvious that the pH in topically applied preparations may play an important role. Optimal pH and buffer capacity within topical preparations not only support stability of active ingredients and auxiliary materials, but may also increase absorption of the non-ionized species of an acidic or a basic active ingredient. They may even open up opportunities to modify and "correct" skin pH and hence accelerate barrier recovery and maintain or enhance barrier integrity. Further efforts are needed to standardize and improve pH measurements in biological media or pharmaceutical/cosmetic vehicles to increase and ensure quality, comparability, and relevance of research data. In this volume, we present a unique collection of papers that address past, present and future issues of the pH of healthy and diseased skin. It is hoped that this collection will foster future efforts in clinical and experimental skin research.

Psoriasis

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535132512
Total Pages : 248 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Psoriasis by : Anca Chiriac

Download or read book Psoriasis written by Anca Chiriac and published by BoD – Books on Demand. This book was released on 2017-07-05 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2014, psoriasis was recognized as a serious noncommunicable disease in the World Health Assembly Resolution WHA67.9, with a great negative impact on patients' quality of life. Psoriasis is a worldwide chronic disease, affecting all ages and all races, and a serious global health problem. Psoriasis is a complex disease with still unknown etiology and no specific curative treatment. The chapters provide comprehensive and new description of some issues related to psoriasis research and for understanding of clinical correlations, genetic aspects, experimental research, and potential therapeutic interventions. The book could be a source of information for clinicians and researchers from different fields in raising awareness of the disease.

Evidence-Based Psoriasis

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Author :
Publisher : Springer
ISBN 13 : 3319901079
Total Pages : 152 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Evidence-Based Psoriasis by : Tina Bhutani

Download or read book Evidence-Based Psoriasis written by Tina Bhutani and published by Springer. This book was released on 2018-06-30 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given the multitude of new treatment options for psoriasis, including topicals, phototherapy, oral systemic therapy, and injectable biologics, the treatment of the disease has truly become an art. Evidence-Based Psoriasis passes on this art to practicing physicians in a very practical and easy-to-use format, focusing on mild, moderate, and severe psoriasis. Offering evidence-based information in a concise text, this book discusses new treatment options, including topicals, phototherapy, oral systemic therapy, and injectable biolgoics. This text also describes unique methods of use, such as sequential and combination therapy, and is written for practicing dermatologists, residents, and primary care physicians. Evidence-Based Psoriasis also includes high quality color photographs and tables for quick and easy reference.

Management of Psoriasis

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805591519
Total Pages : 205 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Management of Psoriasis by : Nikhil Yawalkar

Download or read book Management of Psoriasis written by Nikhil Yawalkar and published by Karger Medical and Scientific Publishers. This book was released on 2009 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treatments for psoriasis, besides affecting the skin, may be associated with various comorbidities (for instance, depression, psoriatic arthritis, Crohn's disease and, in severe psoriasis, metabolic syndrome and cardiovascular diseases), which often presents a therapeutic challenge to physicians.Written by renowned experts, this volume gives a comprehensive overview of psoriasis and its various comorbidities. It describes the treatment modalities for mild and moderate-to-severe psoriasis, including topical, phototherapeutic and conventional systemic treatments (e.g. acitretine, methotrexate and cyclosporine), as well as biological therapies (e.g. alefacept, efalizumab, etanercept, adalimumab and infliximab). The chapters on biological therapies focus on key safety issues. Further chapters focus on such topics as the management of childhood psoriasis and psoriasis in distinctive locations, such as the scalp, face, flexures, palm/soles and nails. Finally, future therapeutic modalities, with the focus on small molecules and potential biological therapies, are discussed.This publication will make significant reading to dermatologists and all physicians dealing with psoriasis, such as general practitioners, psychiatrists, rheumatologists, cardiologists and diabetologists.

Dermatological Diseases and Cumulative Life Course Impairment

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318024031
Total Pages : 172 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Dermatological Diseases and Cumulative Life Course Impairment by : Alexa Boer Kimball

Download or read book Dermatological Diseases and Cumulative Life Course Impairment written by Alexa Boer Kimball and published by Karger Medical and Scientific Publishers. This book was released on 2013 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication presents currently available evidence about the extent to which dermatological diseases may, through their own nature as well as a multitude of comorbidities and their important interactions with social life, impair the life course of patients. Divided into four parts, the book starts with a brilliant introduction that highlights the importance of a life course approach in medicine from a medical as well as from a psychosocial point of view. The second part provides a basic presentation of the theoretical aspects of life course research and, more specifically, to the concepts of allostatic load and cumulative life course impairment (CLCI). The third part examines concepts related to CLCI, such as the 'quality of life in dermatology' or the 'major life changing decisions' influenced by dermatological diseases. The book concludes with an in-depth investigation of specific diseases where the concept of CLCI strikes as particularly relevant. The new and innovative evidence presented in this publication makes it essential reading to anyone who has to take social implications of skin diseases into account in their decision making: dermatologists, allergologists, pediatricians and general practitioners as well as researchers in medical sociology or opinion leaders in public health.

Psoriasis and Psoriatic Arthritis

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Author :
Publisher : CRC Press
ISBN 13 : 1498756077
Total Pages : 369 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Psoriasis and Psoriatic Arthritis by : Siba P. Raychaudhuri

Download or read book Psoriasis and Psoriatic Arthritis written by Siba P. Raychaudhuri and published by CRC Press. This book was released on 2017-12-15 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psoriasis is a life-long chronic autoimmune disease characterized by thick scaly skin lesions and often associated with severe arthritis. In psoriasis, lesions skin cells, keratinocytes, grow too quickly, resulting in thick, white, silvery or red patches on skin. Normal skin cells grow gradually and flake off about every four weeks, but psoriasis causes new skin cells to move rapidly to the surface of the skin in days rather than weeks. Psoriasis symptoms often appear on the elbows, scalp, feet, knees, hands, or lower back, or as flaking or patches on the skin. It is most common in adults, but teenagers and children can also suffer from psoriasis. Psoriasis is not only a skin condition; it is a chronic disease of the immune system. Chronic psoriasis is associated with other health conditions such as psoriatic arthritis, several inflammatory disorders, type 2 diabetes, and cardiovascular disease. This book provides extensive coverage of psoriasis and psoriatic arthritis. It features information on epidemiology and etiology of psoriasis, pathogenesis, genetics of psoriasis, clinical manifestations, and treatment options using cutting-edge drugs including adalimumab and tofacitinib. Natural phytochemicals and nutraceuticals have demonstrated efficacy in ameliorating psoriasis. The book dedicates comprehensive coverage of nutraceutical therapeutic options including antioxidants, bioactive peptides, carotenoids, alpha lipoic acid, curcumin, and whey protein. These inexpensive natural therapeutics are not associated with any known adverse side effects.

Integrative Dermatology

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Author :
Publisher : Oxford University Press
ISBN 13 : 0199907927
Total Pages : 554 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Integrative Dermatology by : Robert A. Norman

Download or read book Integrative Dermatology written by Robert A. Norman and published by Oxford University Press. This book was released on 2014-04 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title combines conventional treatment options with time tested alternative treatment options for skin disorders. By integrating the best of Western and Eastern medicine, it aims to broaden the armamentarium of clinicians treating skin diseases.