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Imaging In Stem Cell Transplant And Cell Based Therapy
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Book Synopsis Imaging in Stem Cell Transplant and Cell-based Therapy by : Tarun Pandey
Download or read book Imaging in Stem Cell Transplant and Cell-based Therapy written by Tarun Pandey and published by Springer. This book was released on 2017-05-29 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a review of imaging techniques and applications in stem cell transplantation and other cell-based therapies. The basis of different molecular imaging techniques is explained in detail, as is the current state of interventional radiology techniques. While the whole is a comprehensive discussion, each chapter is self-sufficient enough so that each can be reviewed independently. The contributors represent years of international and cross-disciplinary expertise and perspective and are all well known in their fields. comprehensive information on the role of clinical and molecular imaging in stem cell therapy from this book reviewed in detail. Essential reading for radiologists and physicians who are interested in developing a basic understanding of stem cell imaging and applications of stem cells and cell based therapies. However, it will also be of interest to clinical scientists and researchers alike, including those involved in stem cell labeling, tracking & imaging, cancer therapy, angiogenesis and cardiac regeneration.
Book Synopsis Magnetic Resonance Imaging of Stem Cell Applications by : Xiaoming Yang
Download or read book Magnetic Resonance Imaging of Stem Cell Applications written by Xiaoming Yang and published by Nova Science Publishers. This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cell-based regenerative therapy has become a frontier in modern medicine. For the success of both basic research and clinical application of stem cell technology, it is essential to have noninvasive methods to monitor the delivery of transplanted stem cells, track migration/homing of stem cells to the targets, and assess survival and function of the transplanted stem cells at the targets. Magnetic resonance imaging (MRI) represents a promising technology fitting in this necessity. So far, scientists from various disciplines around the world have done outstanding works in developing different MR techniques for in vivo imaging of stem cells, so-called cellular MRI. The aim of this book is to facilitate such translation of advanced cellular MRI techniques from laboratory benches to pre-clinical animal studies, and, ultimately, to clinical practice. The authors are from several continents around the world, with their expertise in the fields of stem cell science, biomedical engineering, medicine, pathology, medical imaging, and interventional radiology. We hope this book will provoke common interests, brainstorming and cooperation among professionals in both stem cell science and medical imaging, and bring regenerative medicine one step closer to benefiting the patients.
Book Synopsis Stem Cells and the Future of Regenerative Medicine by : Institute of Medicine
Download or read book Stem Cells and the Future of Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.
Book Synopsis Cell-Based Therapies in Stroke by : Jukka Jolkkonen
Download or read book Cell-Based Therapies in Stroke written by Jukka Jolkkonen and published by Springer Science & Business Media. This book was released on 2013-01-30 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke remains one of the main causes of death and disability worldwide. While effective therapy for stroke recovery remains an unmet need. Much hope and promises are placed on cell-based therapies. The aim of this book is to provide focused yet comprehensive reviews on the current state of cell-based approaches in the treatment of stroke. The topics covered include experimental data on functional outcome after intravascular and intracerebral delivery of cells in stroke animals, followed by translational chapters which will rely heavily on the use of different imaging modalities in the tracking of cells. The last and most challenging part will describe the early phase of clinical studies, providing guidelines for future research and clinical applications. Clearly and concisely written, this text will be a useful resource for neurologists, radiologists, and neuroscientists interested in cell transplantation as a therapeutic strategy for stroke patients.
Download or read book Cell Therapy written by Dwaine F. Emerich and published by Springer. This book was released on 2017-08-25 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive, state-of-the art review of the field of cell therapy. The volume begins with an overview of the breadth of the field and then turns to overviews of imaging technologies that can aid in both safety and efficacy evaluations. The book then turns to numerous contributions detailing the rapidly growing field of stem cell therapies. These sections cover our understanding of the natural roles of stem cells in biology and human disease and then touches on several of the more prominent areas where stem cells are moving rapidly into clinical evaluation including neurodegenerative diseases, muscular dystrophy, cardiac repair, and diabetes. The volume concludes with contributions from experts in oncology, ophthalmology, stem cells, 3-D printing, and biomaterials where the convergence of expertise is leading to unprecedented insights into how to minutely control the in vivo fate and function of transplanted and/or endogeneously mobilized cells. Finally, the book provides insights into the pivotal relationship between academic and industrial partnerships. This volume is designed to touch on the major areas where the field will make its greatest and most immediate clinical impacts. This text will provide a useful resource for physicians and researchers interested in the rapidly changing filed of cell therapy.
Book Synopsis Stem Cell Therapy by : Erik V. Greer
Download or read book Stem Cell Therapy written by Erik V. Greer and published by Nova Publishers. This book was released on 2006 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, auto-immune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinson's disease, and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This new book brings together leading research from throughout the world in this frontier field.
Book Synopsis Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging by : Dara L. Kraitchman
Download or read book Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging written by Dara L. Kraitchman and published by CRC Press. This book was released on 2011-11-18 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging provides a comprehensive overview of cell therapy imaging, ranging from the basic biology of cell therapeutic choices to the preclinical and clinical applications of cell therapy. It emphasizes the use of medical imaging for therapeutic delivery/targeting, cell tracking, and determining therapeutic efficacy. The book first presents background information and insight on the major classes of stem and progenitor cells. It then describes the main imaging modalities and state-of-the-art techniques that are currently employed for stem cell tracking. In the final chapters, leading scholars offer clinical perspectives on existing and potential uses of stem cells as well as the impact of image-guided delivery and tracking in major organ systems. Through clear descriptions and color images, this volume illustrates how noninvasive imaging is used to track stem cells as they repair damaged tissue in the body. With contributions from some of the most prominent preclinical and clinical researchers in the field, the book helps readers to understand the evolving concepts of stem cell labeling and tracking as the field continues to move forward.
Book Synopsis Magnetic Resonance Imaging of Stem Cell Applications by : Xiaoming Yang
Download or read book Magnetic Resonance Imaging of Stem Cell Applications written by Xiaoming Yang and published by . This book was released on 2015 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cell-based regenerative therapy has become a frontier in modern medicine. For the success of both basic research and clinical application of stem cell technology, it is essential to have noninvasive methods to monitor the delivery of transplanted stem cells, track migration/homing of stem cells to the targets, and assess survival and function of the transplanted stem cells at the targets. Magnetic resonance imaging (MRI) represents a promising technology fitting in this necessity. So far, scientists from various disciplines around the world have done outstanding works in developing differ.
Book Synopsis Mesenchymal Stem Cell Therapy by : Lucas G. Chase
Download or read book Mesenchymal Stem Cell Therapy written by Lucas G. Chase and published by Springer Science & Business Media. This book was released on 2012-12-12 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.
Book Synopsis Total Marrow Irradiation by : Jeffrey Y. C. Wong
Download or read book Total Marrow Irradiation written by Jeffrey Y. C. Wong and published by Springer Nature. This book was released on 2020-02-29 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, written by a team of international experts, concisely reviews the rationale and clinical application of image-guided total marrow irradiation, a rapidly emerging area in radiation oncology and hematopoietic cell transplantation. The aim is to provide the practicing radiation oncologist, hematologist, medical physicist, and bone marrow transplant researcher with a fundamental understanding of key aspects and an appreciation of the increasing significance of total marrow irradiation as conditioning for bone marrow transplantation. Detailed attention is paid to the impacts of recent advances in radiation therapy technology, functional PET and MRI, and understanding of the response of bone marrow to radiation. Full consideration is also given to the ways in which technological advances in image-guided radiation therapy have created new opportunities to treat bone marrow transplant patients with limited transplant options due to advanced disease, age, or co-morbidities. Further topics covered include the ways in which cancer stem cells and the marrow microenvironment influence response to radiation therapy and the implementation of new-generation predictive radiobiologic factors in the clinic.
Book Synopsis Bone marrow stem cell therapy for stroke by : Kunlin Jin
Download or read book Bone marrow stem cell therapy for stroke written by Kunlin Jin and published by Springer. This book was released on 2016-12-13 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers recent advances in all aspects of bone marrow-derived stem cells (BMSCs) for stroke treatment, while also providing comprehensive information on human clinical trials and animal models of stroke. In addition, it reviews the optimal conditions of transplantation for stroke therapy and potential mechanisms underlying transplanted cell-mediated functional recovery after stroke. As the first book to focus on BMSC therapy for stroke, it also discusses in depth the unique challenges of BMSCs-based therapy in this context.
Author :R.P. Casaroli-Marano Publisher :Karger Medical and Scientific Publishers ISBN 13 :3318025852 Total Pages :220 pages Book Rating :4.3/5 (18 download)
Book Synopsis Cell-Based Therapy for Retinal Degenerative Disease by : R.P. Casaroli-Marano
Download or read book Cell-Based Therapy for Retinal Degenerative Disease written by R.P. Casaroli-Marano and published by Karger Medical and Scientific Publishers. This book was released on 2014-04-22 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, some of the leading authorities present their exploration of applications of stem cell therapy to the treatment of major causes of blindness, including degenerative diseases and glaucoma. The diagnostic approach to patients, general concepts of cell-based therapy, immunological considerations, approaches to cell delivery (including engineered scaffolds), combined cell and gene therapy, nanomedicine applications to cell therapy and regulatory issues pertaining to manufacture and production are all considered in detail. The book serves as an excellent introduction to a field that is now entering early-stage clinical trials and promises to operate at the leading edge of regenerative medicine. Retina specialists, general ophthalmologists as well as researchers will find here a wealth of information on the translational aspects of cell-based therapies. Further, business executives and students interested in understanding the potential applications of stem cell therapy to retinal degenerative disease and glaucoma will also find this book informative reading.
Book Synopsis Stem Cell-Based Tissue Repair by : Raphael Gorodetsky
Download or read book Stem Cell-Based Tissue Repair written by Raphael Gorodetsky and published by Royal Society of Chemistry. This book was released on 2010-12-03 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need for customized stem cell therapies for specific conditions will be a major issue in the coming decades. This unique book by experts in the field reviews the subject as it stands today. Its coverage includes: basic and applied stem cell research and history; sources of adult stem cells; a comparison of difficulties in derivation, and the applications of embryonic and adult stem cells. Specific topics dealt with include: -advantages and problems associated with stem cell / matrix interactions -stem cell differentiation -difficulties using stem cells for clinical application -stem cell based tissue engineering - myth or reality -stem cells and immunity -natural biological matrices versus synthetic - biocompatibility and integration -stem cell delivery, labeling, imaging and tracking -bioreactors: 2D and 3D cell culturing for in-vitro studies and for stem cell implantation -ethical and safety issues -Good Manufacturing Practice (GMP).
Book Synopsis Mesenchymal Stromal Cells by : Hematti Peiman
Download or read book Mesenchymal Stromal Cells written by Hematti Peiman and published by Academic Press. This book was released on 2016-08-11 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal Stromal Cells: Translational Pathways to Clinical Adoption provides the latest information on the necessary steps for successful production of stem cells for a clinical trial. Written by professionals with hands-on experience in bringing MSC therapies to the clinic, and building on the biology and mechanisms of action, this unique book covers the development and production of clinical-grade products that are suitable for use in humans. From design of a cell production facility, to obtaining regulatory approval and reimbursement issues, it is a useful guide for researchers and administrators across biomedical research. Provides methodologies for clinical MSC production, from designing a facility, to post-market approval Includes real-life examples of MSC production in academic centers and MSC production for biopharmaceutical clinical trials Offers a unique perspective on the clinical aspects of MSC studies Presents the principles of clinical trials that can be applied to the production of various cell therapies
Book Synopsis Stem Cell and Gene-Based Therapy by : Alexander Battler
Download or read book Stem Cell and Gene-Based Therapy written by Alexander Battler and published by Springer Science & Business Media. This book was released on 2007-06-26 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine – stem cell and gene-based therapy – offers a new approach for restoring function of damaged organs and tissues. This is the first book to cover the major new aspects and field of regenerative medicine. This title is therefore a timely addition to the literature. It brings together the major approaches to regenerative medicine in one text, which ensures that techniques learnt in one discipline are disseminated across other areas of medicine.
Book Synopsis Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases by : Richard K. Burt
Download or read book Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases written by Richard K. Burt and published by CRC Press. This book was released on 2021-11-17 with total page 1739 pages. Available in PDF, EPUB and Kindle. Book excerpt: Key Features Outlines therapies and techniques for HSCT for autoimmune diseases, and d Discusses its the advantages of HSCT over conventional therapies Reviews the entire process of stem cell therapy from harvest and ethics to indications of efficacy.
Book Synopsis Progress in Stem Cell Applications by : Allen V. Faraday
Download or read book Progress in Stem Cell Applications written by Allen V. Faraday and published by Nova Publishers. This book was released on 2008 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to recent research in stem cell applications. Stem cells are the foundation cells for every organ, tissue and cell in the body. They are like a blank microchip that can ultimately be programmed to perform any number of specialised tasks. Stem cells are undifferentiated, "blank" cells that do not yet have a specific function. Under proper conditions, stem cells begin to develop into specialised tissues and organs. Additionally, stem cells are self-sustaining and can replicate themselves for long periods of time. These unique characteristics make stem cells very promising for supplying cells to treat debilitating diseases like Alzheimer's disease, cancer, Parkinson's disease, type-1 diabetes, spinal cord injury, stroke, burns, heart disease, osteoarthritis and rheumatoid arthritis.
