Identification Of Two Component Systems That Are Involved In Regulation Of Legionella Pneumophila Pathogenesis

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Management of Legionella in Water Systems

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 030949382X
Total Pages : 291 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Management of Legionella in Water Systems by : National Academies of Sciences, Engineering, and Medicine

Download or read book Management of Legionella in Water Systems written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-02-20 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Legionnaires' disease, a pneumonia caused by the Legionella bacterium, is the leading cause of reported waterborne disease outbreaks in the United States. Legionella occur naturally in water from many different environmental sources, but grow rapidly in the warm, stagnant conditions that can be found in engineered water systems such as cooling towers, building plumbing, and hot tubs. Humans are primarily exposed to Legionella through inhalation of contaminated aerosols into the respiratory system. Legionnaires' disease can be fatal, with between 3 and 33 percent of Legionella infections leading to death, and studies show the incidence of Legionnaires' disease in the United States increased five-fold from 2000 to 2017. Management of Legionella in Water Systems reviews the state of science on Legionella contamination of water systems, specifically the ecology and diagnosis. This report explores the process of transmission via water systems, quantification, prevention and control, and policy and training issues that affect the incidence of Legionnaires' disease. It also analyzes existing knowledge gaps and recommends research priorities moving forward.

Molecular Mechanisms in Legionella Pathogenesis

Author : Hubert Hilbi
Publisher : Springer Science & Business Media
ISBN 13 : 3642405916
Total Pages : 297 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Molecular Mechanisms in Legionella Pathogenesis by : Hubert Hilbi

Download or read book Molecular Mechanisms in Legionella Pathogenesis written by Hubert Hilbi and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Legionnaires’ disease, a potentially fatal type of pneumonia primarily affecting elderly and immuno-compromised persons, is caused by the ubiquitous environmental bacterium Legionella pneumophila. This book offers authoritative reviews of different facets of its virulence, focusing on comparative phagocyte infection, virulence gene regulation, biochemical functions of effector proteins and cellular pathogen-host interactions, as well as host responses and immunity to L. pneumophila. Taken together, the contributions in this compilation provide a state-of-the-art overview of current insights into the molecular pathogenesis of the opportunistic and potentially fatal pathogen L. pneumophila.

Legionella

Author : James M. Barbaree
Publisher : ASM Press
ISBN 13 :
Total Pages : 334 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Legionella by : James M. Barbaree

Download or read book Legionella written by James M. Barbaree and published by ASM Press. This book was released on 1993 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawn from ASM′s 1992 symposium on the subject, this book completely updates information on all aspects of Legionella and Legionnaires disease. Strategy sessions held at the symposium to address current issues involving preventive measures to minimize the presence of Legionella and occurence of Legionnaires disease, the evolution of chemotherapy and diagnostic tests, and prospects for vaccine development are summarized. Legionella is required reading for anyone working in this area of infectious disease. As the sole source of current knowledge and theory on Legionella, it is an extremely useful reference for clinical microbiologists, environmental microbiologists, epidemiologists, infectious disease and other clinical specialists, and environmental engineers.

Microbiology of Waterborne Diseases

Author :
Publisher : Academic Press
ISBN 13 : 0124159761
Total Pages : 719 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Microbiology of Waterborne Diseases by :

Download or read book Microbiology of Waterborne Diseases written by and published by Academic Press. This book was released on 2013-11-08 with total page 719 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Microbiology of Waterborne Diseases describes the diseases associated with water, their causative agents and the ways in which they gain access to water systems. The book is divided into sections covering bacteria, protozoa, and viruses. Other sections detail methods for detecting and identifying waterborne microorganisms, and the ways in which they are removed from water, including chlorine, ozone, and ultraviolet disinfection. The second edition of this handbook has been updated with information on biofilms and antimicrobial resistance. The impact of global warming and climate change phenomena on waterborne illnesses are also discussed. This book serves as an indispensable reference for public health microbiologists, water utility scientists, research water pollution microbiologists environmental health officers, consultants in communicable disease control and microbial water pollution students. Focuses on the microorganisms of most significance to public health, including E. coli, cryptosporidium, and enterovirus Highlights the basic microbiology, clinical features, survival in the environment, and gives a risk assessment for each pathogen Contains new material on antimicrobial resistance and biofilms Covers drinking water and both marine and freshwater recreational bathing waters

Listeria monocytogenes: Pathogenesis and Host Response

Author : Howard Goldfine
Publisher : Springer Science & Business Media
ISBN 13 : 038749376X
Total Pages : 292 pages
Book Rating : 4.3/5 (874 download)

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Book Synopsis Listeria monocytogenes: Pathogenesis and Host Response by : Howard Goldfine

Download or read book Listeria monocytogenes: Pathogenesis and Host Response written by Howard Goldfine and published by Springer Science & Business Media. This book was released on 2007-06-24 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past twenty years Listeria monocytogenes has emerged as one of the most intensely studied bacterial pathogens. New windows are constantly being opened into the complexity of host cell biology and the interplay of the signals connecting the various cells and organs involved in the host response. This volume includes research from studies at the molecular level on the pathogenesis of Listeria monocytogenes and the response of the host to its infections.

Regulation of Bacterial Virulence

Author : Michael L. Vasil
Publisher : American Society for Microbiology Press
ISBN 13 : 1555816762
Total Pages : 1189 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Regulation of Bacterial Virulence by : Michael L. Vasil

Download or read book Regulation of Bacterial Virulence written by Michael L. Vasil and published by American Society for Microbiology Press. This book was released on 2012-12-05 with total page 1189 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive compendium of scholarly contributions relating to bacterial virulence gene regulation. • Provides insights into global control and the switch between distinct infectious states (e.g., acute vs. chronic). • Considers key issues about the mechanisms of gene regulation relating to: surface factors, exported toxins and export mechanisms. • Reflects on how the regulation of intracellular lifestyles and the response to stress can ultimately have an impact on the outcome of an infection. • Highlights and examines some emerging regulatory mechanisms of special significance. • Serves as an ideal compendium of valuable topics for students, researchers and faculty with interests in how the mechanisms of gene regulation ultimately affect the outcome of an array of bacterial infectious diseases.

Bacterial Pathogenesis

Author :
Publisher : Academic Press
ISBN 13 : 0080860567
Total Pages : 643 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Bacterial Pathogenesis by :

Download or read book Bacterial Pathogenesis written by and published by Academic Press. This book was released on 1998-07-01 with total page 643 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established almost 30 years ago, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research. - Focuses on the methods most useful for the microbiologist interested in the way in which bacteria cause disease - Includes section devoted to 'Approaches to characterising pathogenic mechanisms' by Stanley Falkow - Covers safety aspects, detection, identification and speciation - Includes techniques for the study of host interactions and reactions in animals and plants - Describes biochemical and molecular genetic approaches - Essential methods for gene expression and analysis - Covers strategies and problems for disease control

Bacterial Biofilms

Author : Sadik Dincer
Publisher : BoD – Books on Demand
ISBN 13 : 1789858992
Total Pages : 362 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Bacterial Biofilms by : Sadik Dincer

Download or read book Bacterial Biofilms written by Sadik Dincer and published by BoD – Books on Demand. This book was released on 2020-10-07 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines biofilms in nature. Organized into four parts, this book addresses biofilms in wastewater treatment, inhibition of biofilm formation, biofilms and infection, and ecology of biofilms. It is designed for clinicians, researchers, and industry professionals in the fields of microbiology, biotechnology, ecology, and medicine as well as graduate and postgraduate students.

Legionella Pneumophila: Pathogenesis and Immunity

Author : Paul Hoffman
Publisher : Springer Science & Business Media
ISBN 13 : 0387708960
Total Pages : 217 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Legionella Pneumophila: Pathogenesis and Immunity by : Paul Hoffman

Download or read book Legionella Pneumophila: Pathogenesis and Immunity written by Paul Hoffman and published by Springer Science & Business Media. This book was released on 2007-10-24 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume brings together all of the latest research on this pathogen, the interest in which is rapidly growing. Legionella pneumophila is an emerging human pathogen that resides in natural environments as a parasite of freshwater. There have been major new developments in this field, including the publication of three whole genome sequences and the discovery of a developmental cycle and novel cyst-like highly infectious form.

Autophagy in Infection and Immunity

Author : Beth Levine
Publisher : Springer
ISBN 13 : 9783642260377
Total Pages : 339 pages
Book Rating : 4.2/5 (63 download)

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Book Synopsis Autophagy in Infection and Immunity by : Beth Levine

Download or read book Autophagy in Infection and Immunity written by Beth Levine and published by Springer. This book was released on 2012-03-14 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy is a fundamental biological process that enables cells to autodigest their own cytosol during starvation and other forms of stress. It has a growing spectrum of acknowledged roles in immunity, aging, development, neurodegeneration, and cancer biology. An immunological role of autophagy was first recognized with the discovery of autophagy’s ability to sanitize the cellular interior by killing intracellular microbes. Since then, the repertoire of autophagy’s roles in immunity has been vastly expanded to include a diverse but interconnected portfolio of regulatory and effector functions. Autophagy is an effector of Th1/Th2 polarization; it fuels MHC II presentation of cytosolic (self and microbial) antigens; it shapes central tolerance; it affects B and T cell homeostasis; it acts both as an effector and a regulator of Toll-like receptor and other innate immunity receptor signaling; and it may help ward off chronic inflammatory disease in humans. With such a multitude of innate and adaptive immunity functions, the study of autophagy in immunity is one of the most rapidly growing fields of contemporary immunological research. This book introduces the reader to the fundamentals of autophagy, guides a novice and the well-informed reader alike through different immunological aspects of autophagy as well as the countermeasures used by highly adapted pathogens to fight autophagy, and provides the expert with the latest, up-to-date information on the specifics of the leading edge of autophagy research in infection and immunity.

The Molecular Basis of Bacterial Metabolism

Author : Günter Hauska
Publisher : Springer Science & Business Media
ISBN 13 : 3642759696
Total Pages : 190 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Molecular Basis of Bacterial Metabolism by : Günter Hauska

Download or read book The Molecular Basis of Bacterial Metabolism written by Günter Hauska and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume contains 17 lectures of the 41 st Mosbach Colloquium of the Gesellschaft fiir Biologische Chemie, held from April 5-7, 1990 on the topic "The Molecular Basis of Bacterial Metabolism". From the beginning it was not the intention of the organizers to present a comprehensive account, but rather to select new, exciting progress on sometimes exotic reactions of specifically bacterial, mainly anaerobic metabolism. Members of our society had contributed to this progress to an extent that greatly stimulated the scientific exchange with international colleagues during the days in Mosbach. The editors hope that this stimulation will be conveyed to the readers of the articles, which reach from the biochemistry of methanogenesis, via anaerobic radical reactions, metal biochemistry in hydrogen and nitrogen metabolism, conversions of light - and redox energy, to the regulation of metabolic adaptation, and the attempts to bioengineer novel pathways for the degradation of xenobiotica. We believe that the book represents a highly progressive field of over lapping disciplines, comprising microbiology and molecular genetics, chemistry of biomimetic interest, and biophysics, and that it gives insight into the impact modern technologies have on microbiological research today. The colloquium was generously supported by the Deutsche Forschungsgemeinschaft, the Paul-Martini-Stiftung, and the Fonds fiir Biologische Chemie. A. Trebst, G. Schafer, and D. Oesterhelt were a great help in preparing the program and we wish to thank them for their advice.

Severe Community Acquired Pneumonia

Author : Jordi Rello
Publisher : Springer Science & Business Media
ISBN 13 : 9780792373384
Total Pages : 216 pages
Book Rating : 4.3/5 (733 download)

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Book Synopsis Severe Community Acquired Pneumonia by : Jordi Rello

Download or read book Severe Community Acquired Pneumonia written by Jordi Rello and published by Springer Science & Business Media. This book was released on 2001-06-30 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Severe Community Acquired Pneumonia is a book in which chapters are authored and the same topics discussed by North American and European experts. This approach provides a unique opportunity to view the different perspectives and points of view on this subject. Severe CAP is a common clinical problem encountered in the ICU setting. This book reviews topics concerning the pathogenesis, diagnosis and management of SCAP. The discussions on the role of alcohol in severe CAP and adjunctive therapies are important topics that further our understanding of this severe respiratory infection.

Endotoxin in Health and Disease

Author : Helmut Brade
Publisher : CRC Press
ISBN 13 : 1000110389
Total Pages : 968 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Endotoxin in Health and Disease by : Helmut Brade

Download or read book Endotoxin in Health and Disease written by Helmut Brade and published by CRC Press. This book was released on 2020-10-28 with total page 968 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering a basis for further research into the interactions of hosts and pathogens, this work gathers up-to-date findings, and details basic structures, functions and immunology. It provides descriptions of a variety of experimental endotoxin neutralizing agents, as well as a guide to clinical research initiatives and the latest treatments.

Biology and Pathogenesis of Legionella

Author : Hayley Newton
Publisher : Frontiers Media SA
ISBN 13 : 2889456617
Total Pages : 181 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Biology and Pathogenesis of Legionella by : Hayley Newton

Download or read book Biology and Pathogenesis of Legionella written by Hayley Newton and published by Frontiers Media SA. This book was released on 2018-12-07 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Legionella pneumophila was first isolated as the causative agent of a deadly infectious pneumonia at a convention of the American Legion forty years ago. Since then, Legionnaires’ disease continues to be a significant public health concern. Today, our understanding of the Legionella genus, comprising environmental bacteria and opportunistic human pathogens, has dramatically increased. The study of how pathogenic Legionella interact with host cells, both protozoan and mammalian, has not only taught us about host-pathogen interactions but has revealed novel and unexpected insights into human cell biology and immunology. The capacity of pathogenic Legionella to commandeer cellular processes such as eukaryotic vesicular trafficking to establish an ER-like replicative niche, reflects the exquisite ability of this pathogen to manipulate eukaryotic cell biology in order to replicate in an intracellular compartment. This requires the specific and targeted action of a cohort of translocated bacterial effector proteins. In addition, we have learnt much about cell autonomous innate immune sensing of intracellular bacteria through the inability of L. pneumophila to avoid intracellular mammalian defense mechanisms. Now, in the age of large-scale comparative “omics”, it is clear that different Legionella species utilize different cohorts of effectors to replicate inside eukaryotic cells. While we understand some of the strategies employed by L. pneumophila and L. longbeachae to replicate within eukaryotic cells, there is still much to learn about many aspects of the Legionella life cycle. This Research Topic highlights the latest findings regarding the biology of Legionella species, their interactions with eukaryotic host cells, and how the application of various technologies has increased our understanding of this important pathogen.

Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases

Author : John E. Bennett, MD, MACP
Publisher : Elsevier Health Sciences
ISBN 13 : 1455748013
Total Pages : 5094 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases by : John E. Bennett, MD, MACP

Download or read book Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases written by John E. Bennett, MD, MACP and published by Elsevier Health Sciences. This book was released on 2014-08-28 with total page 5094 pages. Available in PDF, EPUB and Kindle. Book excerpt: After thirty five years, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition helps you identify and treat whatever infectious disease you see. Get the answers to questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you'll find in any other infectious disease resource. Find the latest diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on influenza (new pandemic strains); new Middle East respiratory syndrome (MERS) virus; probiotics; antibiotics for resistant bacteria; antifungal drugs; new antivirals for hepatitis B and C; Clostridium difficile treatment; sepsis; advances in HIV prevention and treatment; viral gastroenteritis; Lyme disease; Helicobacter pylori; malaria; infections in immunocompromised hosts; immunization (new vaccines and new recommendations); and microbiome. Benefit from fresh perspectives and global insights from an expanded team of international contributors. Find and grasp the information you need easily and rapidly with newly added chapter summaries. These bulleted templates include diagnosis, therapy, and prevention and are designed as a quick summary of the chapter and to enhance relevancy in search and retrieval on Expert Consult. Stay current on Expert Consult with a thorough and regularly scheduled update program that ensures access to new developments in the field, advances in therapy, and timely information. Access the information you need easily and rapidly with new succinct chapter summaries that include diagnosis, therapy, and prevention. Experience clinical scenarios with vivid clarity through a richly illustrated, full-color format that includes 1500 photographs for enhanced visual guidance.

Pathogenic Bacteria

Author : Sahra Kırmusaoğlu
Publisher : BoD – Books on Demand
ISBN 13 : 1789859875
Total Pages : 248 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Pathogenic Bacteria by : Sahra Kırmusaoğlu

Download or read book Pathogenic Bacteria written by Sahra Kırmusaoğlu and published by BoD – Books on Demand. This book was released on 2020-12-09 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathogenic bacteria are the main problem in hospital- and community-acquired infections. As bacteria continue to develop more resistance to antibiotics, it is imperative to develop antibacterial treatment strategies. Written by experts from all over the world, this book examines pathogenic bacteria and their link to multidrug resistance. Over thirteen chapters, it presents examples of pathogenesis, virulence factors, and treatment strategies.

Metal Ions in Gene Regulation

Author : Simon Silver
Publisher : Springer Science & Business Media
ISBN 13 : 1461559936
Total Pages : 479 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Metal Ions in Gene Regulation by : Simon Silver

Download or read book Metal Ions in Gene Regulation written by Simon Silver and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first volume on the role of metal ions in regulating genes to focus not only on toxicity effects of metals but also on the role of metal ions in normal metabolisms, in both prokaryotes and in eukaryotes. This book is a comprehensive treatment of the role of metal ions in gene regulation, and it will be of great utility for those doing basic biological and biomedical research.