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Identification Of Prognostic And Predictive Gene Expression Signatures In A Novel Mouse Model Of Colon Cancer
Download Identification Of Prognostic And Predictive Gene Expression Signatures In A Novel Mouse Model Of Colon Cancer full books in PDF, epub, and Kindle. Read online Identification Of Prognostic And Predictive Gene Expression Signatures In A Novel Mouse Model Of Colon Cancer ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Genetics of Colorectal Cancer by : John D. Potter
Download or read book Genetics of Colorectal Cancer written by John D. Potter and published by Springer. This book was released on 2008-12-08 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic susceptibility refers to how variations in a person’s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This volume will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers. Topics will include germline susceptibility, including Mendelian patterns of inheritance and gene-environment interactions that lead to cancer etiology.
Book Synopsis Hepatocellular Carcinoma by : Yujin Hoshida
Download or read book Hepatocellular Carcinoma written by Yujin Hoshida and published by Springer. This book was released on 2019-08-05 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the current limitations and unmet needs in Hepatocellular Carcinoma (HCC) diagnosis, treatment, and prevention. It also provides newly emerging concepts, approaches, and technologies to address challenges. Topics covered include changing landscape of HCC etiologies in association with health disparities, framework of clinical management algorithm, new and experimental modalities of HCC diagnosis and prognostication, multidisciplinary treatment options including rapidly evolving molecular targeted therapies and immune therapies, multi-omics molecular characterization, and clinically relevant experimental models. The book is intended to assist collaboration between the diverse disciplines and facilitate forward and reverse translation between basic and clinical research by providing a comprehensive overview of relevant areas, covering epidemiological trend and population-level patient management strategies, new diagnostic and prognostic tools, recent advances in the standard care and novel therapeutic approaches, and new concepts in pathogenesis and experimental approaches and tools, by experts and opinion leaders in their respective fields. By thoroughly and concisely covering whole aspects of HCC care, Hepatocellular Carcinoma serves as a valuable reference for multidisciplinary readers, and promotes the development of personalized precision care strategies that lead to substantial improvement of disease burden and patient prognosis in HCC.
Book Synopsis Immunological Surveillance by : Macfarlane Burnet
Download or read book Immunological Surveillance written by Macfarlane Burnet and published by Elsevier. This book was released on 2014-05-17 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunological Surveillance
Book Synopsis Identifying Clinically Relevant Transcriptional Signatures and Methylation Profiles in the Course, Treatment and Outcome of Colorectal Cancer by : Zora Lasabova
Download or read book Identifying Clinically Relevant Transcriptional Signatures and Methylation Profiles in the Course, Treatment and Outcome of Colorectal Cancer written by Zora Lasabova and published by Frontiers Media SA. This book was released on 2024-03-28 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite major efforts to stratify colorectal cancer patients, only a few prognostic and predictive biomarkers are still used in clinical practice. Inter- and intratumoral heterogeneity is one of the factors influencing strategies for biomarker identification and their implementation in clinical decisions. Recent characterization of consensus molecular subtypes has demonstrated the importance of transcriptome analysis, but the need for in-depth analysis considering other parameters has become apparent. Strategies to study and understand inter- and intratumoral heterogeneity at the tumor tissue level, focusing on gene expression, transcriptomics, and epigenetics, may improve colorectal cancer classification and lead to the identification of biomarkers of prognostic and predictive importance to complement genetics. They could lead to a better understanding of the causes of treatment failure and disease recurrence and thus to new possibilities for patient stratification. Liquid biopsy is currently an effective strategy to capture tumor heterogeneity in non-invasive monitoring of disease progression and recurrence.
Book Synopsis Abeloff's Clinical Oncology E-Book by : John E. Niederhuber
Download or read book Abeloff's Clinical Oncology E-Book written by John E. Niederhuber and published by Elsevier Health Sciences. This book was released on 2013-09-12 with total page 2712 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical and clinically focused, Abeloff’s Clinical Oncology is a trusted medical reference book designed to capture the latest scientific discoveries and their implications for cancer diagnosis and management of cancer in the most accessible manner possible. Abeloff’s equips everyone involved - from radiologists and oncologists to surgeons and nurses - to collaborate effectively and provide the best possible cancer care. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Select the most appropriate tests and imaging studies for cancer diagnosis and staging of each type of cancer, and manage your patients in the most effective way possible by using all of the latest techniques and approaches in oncology. Enhance your understanding of complex concepts with a color art program that highlights key points and illustrates relevant scientific and clinical problems. Stay at the forefront of the latest developments in cancer pharmacology, oncology and healthcare policy, survivorship in cancer, and many other timely topics. See how the most recent cancer research applies to practice through an increased emphasis on the relevance of new scientific discoveries and modalities within disease chapters. Streamline clinical decision making with abundant new treatment and diagnostic algorithms as well as concrete management recommendations. Take advantage of the collective wisdom of preeminent multidisciplinary experts in the field of oncology, including previous Abeloff’s editors John E. Niederhuber, James O. Armitage, and Michael B. Kastan as well as new editors James H. Doroshow from the National Cancer Institute and Joel E. Tepper of Gunderson & Tepper: Clinical Radiation Oncology. Quickly and effortlessly access the key information you need with the help of an even more user-friendly, streamlined format. Access the complete contents anytime, anywhere at Expert Consult, and test your mastery of the latest knowledge with 500 online multiple-choice review questions.
Book Synopsis Biomedical Data Visualization: Methods and Applications by : Guangchuang Yu
Download or read book Biomedical Data Visualization: Methods and Applications written by Guangchuang Yu and published by Frontiers Media SA. This book was released on 2022-05-24 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Identification of immune-related biomarkers for cancer diagnosis based on multi-omics data by : Liang Cheng
Download or read book Identification of immune-related biomarkers for cancer diagnosis based on multi-omics data written by Liang Cheng and published by Frontiers Media SA. This book was released on 2023-02-02 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Understanding Gamma Delta T Cell Multifunctionality - Towards Immunotherapeutic Applications by : Kenth Gustafsson
Download or read book Understanding Gamma Delta T Cell Multifunctionality - Towards Immunotherapeutic Applications written by Kenth Gustafsson and published by Frontiers Media SA. This book was released on 2020-07-02 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :United States. Public Health Service. Office of the Surgeon General Publisher : ISBN 13 : Total Pages :728 pages Book Rating :4.:/5 (318 download)
Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Book Synopsis Unveiling the Tumor Microenvironment by Machine Learning to Develop New Immunotherapeutic Strategies (Volume I.A) by : Nan Zhang
Download or read book Unveiling the Tumor Microenvironment by Machine Learning to Develop New Immunotherapeutic Strategies (Volume I.A) written by Nan Zhang and published by Frontiers Media SA. This book was released on 2023-10-24 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tumor microenvironment (TME) plays a critical role in tumor proliferation, progression, and therapeutic responses. TME is a complex network of cancer cells, stromal cells, and, most importantly, infiltrating immune cells. Cancer cells regulate numerous biological functions through direct or indirect interaction with TME components. Emerging evidence suggests that TME crucially influences the response to both chemotherapy and immunotherapy. As scientific research has entered the big data era with the fast development of high-throughput sequencing technologies, machine learning has been gradually widely applied to extract important knowledge from big data bioinformatics. Thus, characterizing the TME landscape in cancer and identifying different immune-related TME phenotypes using machine learning-based bioinformatics analyses, in vitro experiments, and in vivo experiments are of great interest and significance.
Book Synopsis Molecular Pathology by : William B. Coleman
Download or read book Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2017-11-09 with total page 805 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. - Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease - Explains the practice of "molecular medicine and the translational aspects of molecular pathology - Teaches from the perspective of "integrative systems biology - Enhanced digital version included with purchase
Book Synopsis Current Management of Malignant Melanoma by : Ming Yu Cao
Download or read book Current Management of Malignant Melanoma written by Ming Yu Cao and published by BoD – Books on Demand. This book was released on 2011-09-22 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Management of melanoma is challenging, especially for the late stage of the disease. Development of new therapies and optimizing current treatments are being pursued in attempt to further improve the survival rate. The book provides up-to-date knowledge and experience in early diagnosis, prevention and treatment of melanoma as well as current ongoing clinical studies on melanoma. The book also provides the most recent perspectives of research on the molecular basis of melanoma, such as melanoma associated genes and a possible link between stress and melanoma.
Book Synopsis Biomarkers of the Tumor Microenvironment by : Lars A. Akslen
Download or read book Biomarkers of the Tumor Microenvironment written by Lars A. Akslen and published by Springer Nature. This book was released on 2022-07-12 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Methodological advancements and practical applications, in terms of how biomarkers are studied and increasingly included in clinical trials and therapy protocols, are described and discussed. Biomarkers of the Tumor Microenvironment is an educational resource for students and members of the cancer research community as a whole, especially for those using morphology analysis techniques and models focusing on the cross-talk between different cell types in tumors. The textbook provides a comprehensive overview of the microenvironment in various contexts from the perspectives of experienced and accomplished cancer researchers and clinicians.
Download or read book The Fourth Marker written by L. Gibbons and published by Createspace Independent Pub. This book was released on 2013-05-14 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a supernatural undercurrent, The Fourth Marker is the story of an elderly man, Gabriel Townsend, whose spirit is being crushed between the metaphoric anvil of his pragmatic views and the falling hammer of his wife's pending death. The story revolves around a family, the Townsends, whose heritage is partly Native American.The United States' Indian Removal Act of 1830, which resulted in the Trail of Tears episode in American history, required all indigenous people, with few exceptions, to leave their tribal lands in the southeast and east, along the eastern seaboard. Some Lenape (Delaware) tribal members on the Delmarva Peninsula as well as other areas in the east, defied the government and remained on their ancestral lands, hiding from authorities in the Great Pocomoke Forest, outlying islands, and swamps on the southern peninsula.A conscious decision to "hide in plain sight" or not, they eventually intermarried and bred with local whites, African-Americans, and mulattoes. Many families whose ties to Delmarva date back a hundred years or more share a heritage with those aboriginal people; however, the prejudice and racial bias of a bygone era caused many to ignore – even deny – their lineage.In the story, while a child on the family farm during the Great Depression, Gabe Townsend rejected legends of his Native American ancestors and ignored miraculous cures of family members. Gabe's half-breed grandfather, Noopah, tried to teach him tribal legends and the old ways, explaining that, after most Indians had been killed or driven from their lands by the Army and settlers, tribal elders returned to their lands in spirit form after their deaths. They dwelled at a sacred hill on the family's land and protected their descendants from early death and white man's diseases.During those years, three family members were cured of life-threatening diseases, but Gabe's mother blindly credited their recoveries to the nascent field of modern medicine. After each recovery, a person of evil character and not of tribal blood disappeared, followed by the mysterious appearance of a wood marker on the sacred tribal hill. Yet, despite those events and Noopah's words, Gabe adhered to his mother's intractable views.Now facing the loss of his wife, he relives his childhood memories, guided by the spirit of his grandfather from beyond – well beyond – the grave. Finally understanding the truth of long ago, he decides to beg the tribal spirits to take his life in exchange for his wife's, aware that a fourth marker would signify his own life – and death.As Gabe's father noted, "some understand only what they see; others see only what they understand." The Fourth Marker highlights this most human of vices against the backdrop of Native American legends with ample helpings of farm life during the Great Depression.
Book Synopsis Letter Tracing Book Handwriting Alphabet for Preschoolers Cute Dinosaur by : John J Dewald
Download or read book Letter Tracing Book Handwriting Alphabet for Preschoolers Cute Dinosaur written by John J Dewald and published by Independently Published. This book was released on 2019-07 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Great letter tracing practice for kids! This fun book is a great way for children ages 3 and up to learn the letters of the alphabet and practice fine motor skills for preschool and kindergarten. DETAILS: 108 Writing Pages, Dimensions: 8.5" x 11"
Book Synopsis Cancer: Principles & Practice of Oncology by : Vincent T. DeVita
Download or read book Cancer: Principles & Practice of Oncology written by Vincent T. DeVita and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawn from the content of the new Ninth Edition of Cancer: Principles and Practice of Oncology, this unique publication brings together the basic scientific information on the molecular biology of cancer. The format is designed to be useful both to research scientists interested in the study of cancer and to oncologists who need to understand these new developments that are having a profound impact on the care of patients with cancer. Leading scientists and clinicians in the field of molecular biology and clinical oncology have lent their expertise to this project. The text has been divided into two parts. Part I includes thirteen chapters that deal with the general principles of the molecular biology of cancer that provide the basic framework for an understanding of the behavior of cancer cells. Part II includes an up-to-date description of how this new information has affected the understanding of the biology of 19 of the most common cancers, with an emphasis on how these new findings have been translated to impact the management of cancer patients. This distinctive text provides a single concise source of information for scientists and clinicians in this rapidly developing field
Book Synopsis Identification, function and mechanisms of interferon induced genes associated with viruses by : Chang Li
Download or read book Identification, function and mechanisms of interferon induced genes associated with viruses written by Chang Li and published by Frontiers Media SA. This book was released on 2023-02-15 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt:
