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Icrp Publication 62
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Download or read book ICRP Publication 62 written by ICRP, and published by SAGE Publications Limited. This book was released on 1993-05-01 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years much progress has been made in radiological methods, in dosimetry, and in the knowledge of radiation effects. The ICRP has increased its risk estimates, and in addition, more extensive information has become available on the effect of age at exposure, on gender differences, on the magnitude of risk and on the consequences on in utero irradiation. The objective of Radiological Protection in Biomedical Research is to provide advice to individuals planning such research, those involved in issuing general rules of conduct, and those engaged in evaluation of specific research projects. The report should also be made available to those who may become the subject of investigations (patients, volunteers). Published with this report is a Summary of the current ICRP Principles for Protection of the Patient in Diagnostic Radiology. This has been prepared to encourage medical professionals to become aware of and to utilise those basic principles, and is an update of a previous summary that appeared in ICRP Publication 57 (1989). Finally, the report includes Addendum 1 to ICRP Publication 53 on Radiation Dose to Patients from Radiopharmaceuticals; this part of the report however is superseded by ICRP Publication 80.
Book Synopsis Drug Discovery and Evaluation: Methods in Clinical Pharmacology by : H.Gerhard Vogel
Download or read book Drug Discovery and Evaluation: Methods in Clinical Pharmacology written by H.Gerhard Vogel and published by Springer Science & Business Media. This book was released on 2010-12-15 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
Book Synopsis An Introduction to Radiation Protection in Medicine by : Jamie V. Trapp
Download or read book An Introduction to Radiation Protection in Medicine written by Jamie V. Trapp and published by CRC Press. This book was released on 2008-03-13 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining facets of health physics with medicine, An Introduction to Radiation Protection in Medicine covers the background of the subject and the medical situations where radiation is the tool to diagnose or treat human disease. Encouraging newcomers to the field to properly and efficiently function in a versatile and evolving work setting,
Book Synopsis Radiation Dose from Multidetector CT by : Denis Tack
Download or read book Radiation Dose from Multidetector CT written by Denis Tack and published by Springer Science & Business Media. This book was released on 2012-06-05 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computed tomography (CT) is a powerful technique providing precise and confident diagnoses. The burgeoning use of CT has resulted in an exponential increase in collective radiation dose to the population. Despite investigations supporting the use of lower radiation doses, surveys highlight the lack of proper understanding of CT parameters that affect radiation dose. Dynamic advances in CT technology also make it important to explain the latest dose-saving strategies in an easy-to-comprehend manner. This book aims to review all aspects of the radiation dose from CT and to provide simple rules and tricks for radiologists and radiographers that will assist in the appropriate use of CT technique. The second edition includes a number of new chapters on the most up-to-date strategies and technologies for radiation dose reduction while updating the outstanding contents of the first edition. Vendor perspectives are included, and an online image gallery will also be available to readers.
Book Synopsis Practical Radiation Protection in Healthcare by : Colin J. Martin
Download or read book Practical Radiation Protection in Healthcare written by Colin J. Martin and published by Oxford University Press, USA. This book was released on 2015 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by practitioners experienced in the field, 'Practical Radiation Protection in Healthcare' provides a practical guide for medical physicists and others involved with radiation protection in the healthcare environment.
Book Synopsis Research Ethics for Environmental Health by : Friedo Zölzer
Download or read book Research Ethics for Environmental Health written by Friedo Zölzer and published by Routledge. This book was released on 2021-12-19 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research Ethics for Environmental Health explores the ethical basis of environmental health research and related aspects of risk assessment and control. Environmental health encompasses the assessment and control of those environmental factors that can potentially affect human health, such as radiation, toxic chemicals and other hazardous agents. It is often assumed that the assessment part is just a matter of scientific research, and that control is a matter of implementing standards that unambiguously follow from that research. But it is less commonly understood that environmental health also requires addressing questions of an ethical nature. Coming from multiple disciplines and nine different countries, the contributors to this book critically examine a diverse range of ethical concerns in modern environmental health research. This book will be of great interest to scholars and practitioners of environmental health, as well as researchers in applied ethics, environmental ethics, medical ethics, bioethics and those concerned with chemical and radiation protection.
Book Synopsis Social and Ethical Aspects of Radiation Risk Management by : Deborah Oughton
Download or read book Social and Ethical Aspects of Radiation Risk Management written by Deborah Oughton and published by Newnes. This book was released on 2013-09-07 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Social and Ethical Aspects of Radiation Risk Management provides a comprehensive treatment of the major ethical and social issues resulting from the use of ionizing radiation. It covers topics such as nuclear fuel cycles, radioactive waste treatment, nuclear bomb testing, nuclear safety management, stakeholder engagement, cleanup after nuclear accidents, ecological risks from radiation, environmental justice, health and safety for radiation workers, radiation dose standards, the ethics of clinical radiology, and the principles of radiation protection and their ethical underpinnings. With authors ranging from philosophers to radiation protection officials and practitioners, the book spans from theoretical to practical implications of this important area of radiation risk assessment and management. Covers all the major social and ethical issues in relation to radiation protection Information is easily accessible and non-technical Authors include leading radiation protection officials as well as specialists who are more independent of the radiation protection system, thus presenting both authoritative and more critical views Includes theoretical perspectives as well as practical experience
Book Synopsis Radiation Protection in Medical Imaging and Radiation Oncology by : Richard J. Vetter
Download or read book Radiation Protection in Medical Imaging and Radiation Oncology written by Richard J. Vetter and published by CRC Press. This book was released on 2016-01-05 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiation Protection in Medical Imaging and Radiation Oncology focuses on the professional, operational, and regulatory aspects of radiation protection. Advances in radiation medicine have resulted in new modalities and procedures, some of which have significant potential to cause serious harm. Examples include radiologic procedures that require ve
Book Synopsis Handbook of Radiotherapy Physics by : P Mayles
Download or read book Handbook of Radiotherapy Physics written by P Mayles and published by CRC Press. This book was released on 2007-06-12 with total page 1472 pages. Available in PDF, EPUB and Kindle. Book excerpt: From background physics and biological models to the latest imaging and treatment modalities, the Handbook of Radiotherapy Physics: Theory and Practice covers all theoretical and practical aspects of radiotherapy physics. In this comprehensive reference, each part focuses on a major area of radiotherapy, beginning with an introduction by the
Book Synopsis Handbook of Nuclear Medicine and Molecular Imaging for Physicists by : Michael Ljungberg
Download or read book Handbook of Nuclear Medicine and Molecular Imaging for Physicists written by Michael Ljungberg and published by CRC Press. This book was released on 2022-02-08 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical modelling is an important part of nuclear medicine. Therefore, several chapters of this book have been dedicated towards describing this topic. In these chapters, an emphasis has been put on describing the mathematical modelling of the radiation transport of photons and electrons, as well as on the transportation of radiopharmaceuticals between different organs and compartments. It also includes computer models of patient dosimetry. Two chapters of this book are devoted towards introducing the concept of biostatistics and radiobiology. These chapters are followed by chapters detailing dosimetry procedures commonly used in the context of diagnostic imaging, as well as patient-specific dosimetry for radiotherapy treatments. For safety reasons, many of the methods used in nuclear medicine and molecular imaging are tightly regulated. Therefore, this volume also highlights the basic principles for radiation protection. It discusses the process of how guidelines and regulations aimed at minimizing radiation exposure are determined and implemented by international organisations. Finally, this book describes how different dosimetry methods may be utilized depending on the intended target, including whole-body or organ-specific imaging, as well as small-scale to cellular dosimetry. This text will be an invaluable resource for libraries, institutions, and clinical and academic medical physicists searching for a complete account of what defines nuclear medicine. The most comprehensive reference available providing a state-of-the-art overview of the field of nuclear medicine Edited by a leader in the field, with contributions from a team of experienced medical physicists, chemists, engineers, scientists, and clinical medical personnel Includes the latest practical research in the field, in addition to explaining fundamental theory and the field's history
Book Synopsis The Handbook of Radiopharmaceuticals by : Azuwuike Owunwanne
Download or read book The Handbook of Radiopharmaceuticals written by Azuwuike Owunwanne and published by Springer. This book was released on 2012-12-06 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: One Radiobiopharmaceutics.- 1 Preparation of radiopharmaceuticals.- Production of radionuclides.- Synthesis of the non-radioactive compound.- Reaction of the radionuclide with the non-radioactive compound.- References.- 2 Ideal characteristics of radiopharmaceuticals.- Availability and cost.- Preparation.- Biologic behavior.- Radionuclidic characteristics.- Hematology.- 3 Quality control of radiopharmaceuticals.- Biologic tests.- Physicochemical tests.- References.- 4 Design of radiopharmaceuticals.- Radionuclide.- Chemistry.- Biology.- Human studies.- Registration.- References.- 5 The fate of.
Book Synopsis Technetium-99m Pharmaceuticals by : Ilse Zolle
Download or read book Technetium-99m Pharmaceuticals written by Ilse Zolle and published by Springer Science & Business Media. This book was released on 2007-01-28 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioactive drug development is a multi-disciplinary task. Therefore, dedicated scientists and experts from different fields of specialisation have contributed to this book. The text reviews forty years of advances in radiopharmaceutical development based on Technetium. The first section reviews basic principles and analytic methods, and information on chemical makeup of radiopharmaceuticals. Part 2 reviews 99mTc-radiopharmaceuticals used in nuclear medicine, thoroughly outlining their chemistry, formulation, pharmacokinetics and clinical applications.
Book Synopsis SPECT Imaging of the Brain by : R. Duncan
Download or read book SPECT Imaging of the Brain written by R. Duncan and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the developed world, images of brain structure are available as an everyday diagnostic aid, and the characteristic appearances of most pathological conditions can be looked up in a textbook. Functional brain imaging is to this day less widely used, partly because most pressing diagnostic questions can be answered by refer ence to the patient's cerebral anatomy, partly for reasons of technical limitations of functional techniques. PET as a technique is sufficiently resource-demanding and complex to inhibit its use as an everyday diagnostic technique. SPECT lacked suitable tracers for many years, and early systems had poor spatial resolution. However, rotating gamma camera technology has advanced to the point where images of the brain of reasonable quality can be obtained at most large hospitals, and practical tracers, particularly of regional cerebral blood flow, are easily avail able. As research advances, clinical applications are emerging. A recent report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology! details a number of currently recognised clinical appli cations, some of which are dealt with in this book. Given this recognition, it is increasingly important that clinicians (particularly neuroclinicians, psychiatrists and specialists in cerebrovascular disease), nuclear medicine specialists and physicists acquire an idea of the major applications of the technique, and the research background on which these applications are based.
Download or read book 99mTc-Sestamibi written by Jan Bucerius and published by Springer Science & Business Media. This book was released on 2011-09-22 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: 99mTc-sestamibi is a single-photon emission computed tomography (SPECT) radiotracer that is widely used for the imaging of myocardial perfusion, as well as a variety of malignant and benign diseases. 99mTc-Sestamibi – Clinical Applications provides a detailed and informative overview of almost all the oncologic and non-oncologic applications of 99mTc-sestamibi SPECT, including several relatively rare indications. Different disease-related protocols for 99mTc-sestamibi SPECT are presented, and for each disease a comprehensive summary of the relevant pathology and epidemiology is provided. Throughout, there is a strong emphasis on the practical aspects of use of this popular tracer, including instructions for the preparation of several commercially available tracer kits. Clinical practitioners will find this book to be an invaluable guide to the application and benefits of 99mTc-sestamibi SPECT in both the inpatient and the outpatient setting.
Book Synopsis Metabolite Safety in Drug Development by : Suzanne L. Iverson
Download or read book Metabolite Safety in Drug Development written by Suzanne L. Iverson and published by John Wiley & Sons. This book was released on 2016-08-01 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: A reference on drug metabolism and metabolite safety in the development phase, this book reviews the analytical techniques and experimental designs critical for metabolite studies. It features case studies of lessons learned and real world examples, along with regulatory perspectives from the US FDA and EMA. • Reviews the analytical techniques and experimental designs critical for metabolite studies • Covers methods including chirality, species differences, mass spectrometry, radiolabels, and in vitro / in vivo correlation • Discusses target pharmacology, in vitro systems aligned to toxicity tests, and drug-drug interactions • Includes perspectives from authors with firsthand involvement in industry and the study of drug metabolites, including viewpoints that have influenced regulatory guidelines
Book Synopsis Trends On The Role Of Pet In Drug Development by : Philip H Elsinga
Download or read book Trends On The Role Of Pet In Drug Development written by Philip H Elsinga and published by World Scientific. This book was released on 2012-02-29 with total page 799 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug development is very expensive and a fight against time. PET offers possibilities to speed up this process by adding unique in vivo information on pharmacokinetics/dynamics of a drug at an early stage. This information can help decision makers to move the drug in the drug development process or to decide to stop further developments. This unique and complete book highlights the different ways PET can be used and describes the latest trends in the various disciplines within nuclear medicine to further improve methodologies and increase the number of tools to accelerate drug development. Various topics within tracer development, instrumentation, data analysis and many clinical and preclinical topics are described by leading scientists from industry and academia.
Book Synopsis A Handbook of Bioanalysis and Drug Metabolism by : Gary Evans
Download or read book A Handbook of Bioanalysis and Drug Metabolism written by Gary Evans and published by CRC Press. This book was released on 2021-10-15 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen a greater industrial emphasis in undergraduate and postgraduate courses in the pharmaceutical and chemical sciences. However, textbooks have been slow to adapt, leaving the field without a text/reference that is both instructional and practical in the industrial setting – until now. A Handbook of Bioanalysis and Drug Metabolismis a stimulating new text that examines the techniques, methodology, and theory of bioanalysis, pharmacokinetics, and metabolism from the perspective of scientists with extensive professional experience in drug discovery and development. These three areas of research help drug developers to optimize the active component within potential drugs thereby increasing their effectiveness, and to provide safety and efficacy information required by regulators when granting a drug license. Professionals with extensive experience in drug discovery and development as well as specialized knowledge of the individual topics contributed to each chapter to create a current and well-credentialed text. It covers topics such as high performance liquid chromatography, protein binding, pharmacokinetics and drug–drug interactions. The unique industrial perspective helps to reinforce theory and develop valuable analytical and interpreting skills. This text is an invaluable guide to students in courses such as pharmaceutical science, pharmacology, chemistry, physiology and toxicology, as well as professionals in the biotechnology industry.
