Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Host Defenses And Immunomodulation To Intracellular Pathogens
Download Host Defenses And Immunomodulation To Intracellular Pathogens full books in PDF, epub, and Kindle. Read online Host Defenses And Immunomodulation To Intracellular Pathogens ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Host Defenses and Immunomodulation to Intracellular Pathogens by : Ward E. Bullock
Download or read book Host Defenses and Immunomodulation to Intracellular Pathogens written by Ward E. Bullock and published by Springer. This book was released on 2014-11-14 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: This conference was held under the sponsorship of the Eastern Pennsylvania Branch of the American Society for Microbiology, as one in a continuing series of Basic Science Symposia. The untiring volunteer effects of the members of the Symposium Committee are deeply appreciated. The Bureau of Laboratories of the Pennsylvania Department of Health was a cosponsor and generously provided staff and secretarial services to handle the difficult task of registration. The Department of Microbiology and of Microbiology and Immunology at the five medical schools in Philadelphia -- Temple University School of Medicine, Medical College of Pennsylvania, Thomas Jefferson University, Hahnemann University and the University of Pennsylvania -- were academic cosponsors, and the support of the Chairpersons and the faculties are gratefully acknowledged.
Book Synopsis Host Defenses to Intracellular Pathogens by : Toby K. Eisenstein
Download or read book Host Defenses to Intracellular Pathogens written by Toby K. Eisenstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject matter of this volume was the basis for a confer ence held in Philadelphia in June, 1981, and is an important one in the contemporary area of how the host interacts with micro organisms. In conception, it grew out of a graduate course entitled, "The Infectious Process," which has been taught in the Department of Microbiology and Immunology at Temple University School of Medicine during the past twelve years. This course has explored the broad areas of mechanisms of microbial pathogenesis and host resistance by in-depth consideration of selected models of experimental infection and immunity, as well as the clinical literature. It is noteworthy that there is no adequate text for this material, as the subject matter naturally crosses a wide spectrum of traditional disciplinary lines, encompassing topics as diverse as the mechanisms of action of bacterial toxins, the role of complement and antibody in phagocytosis, and the importance of cross-reacting bacterial polysaccharide antigens in vaccine development. A major portion of the course has always considered "cellular immunity" as it applies to host defenses to intracellular pathogens. It is in this area that the necessity for amalgamation of information from different disciplines is most evident, for one must be intimately concerned with the interactions between the microbe and the phagocyte, both before and after specific immune recognition.
Book Synopsis Molecular Biology of The Cell by : Bruce Alberts
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biology of Growth Factors by : J. E. Kudlow
Download or read book Biology of Growth Factors written by J. E. Kudlow and published by Springer. This book was released on 1988-07-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Growth factors are elaborated to control the growth of cells in such physiological processes as wound healing, tissue regeneration and the immune response. Abnormal production of these growth factors, their receptors or intracellular med!ators of their action may lead to disease states including oncogenesis. This volume will focus on exciting developments in defining the precise molecular lesions that permit the conversion of controlled proliferative signals to neoplasia, on the possible involvement of growth factors in the development of blood vessel diseases as seen in diabetes and atherosclerosis, on the altered immune surveillance that leads to autoimmunity and on the fundamental mechanisms by which growth factors signal their target cells. We expect that the contents of this volume will help promote understanding of the role of these fundamental biological processes and their alterations in a wide variety of disease states and stimulate new investi gations in this important area of biomedical research. The Editors v CONTENTS PERSPECTIVES ON THE CONTROL OF GROWTH AND DIFFERENTIATION Perspectives on the Biology of Growth Factors . . . •. . . . . . . . . . . . . . . • I. B. Fritz Platelet-Derived Growth Factor- Its Role in Health and Disease. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 R. Ross and E. W. Raines Molecular and Developmental Biology Aspects of Fibroblast Growth Factor. • . . . . . . . . . . . . . . • . . . . . . . . . • • . . . . . . . . . . . . . . . . . . • 23 D. Gospodarowicz Chemical and Biochemical Properties of Human Angiogenin. . . . . . . . . . 41 B. L. Vallee and J. F. Riordan GROWTH FACTOR - ONCOGENE RELATIONSHIPS Structure - Function Relationships in Cellular and Viral fps/fes Cytoplasmic Protein-Tyrosine Kinases. . . . . . . . . . . . . . . . . . . . . . . . 55 T. Pawson. P. Greer, M. Moran, K.
Book Synopsis Immune Response Activation and Immunomodulation by : Rajeev Tyagi
Download or read book Immune Response Activation and Immunomodulation written by Rajeev Tyagi and published by BoD – Books on Demand. This book was released on 2019-04-17 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Response Activation and Immunomodulation has been written to address the perceived needs of both medical school and undergraduate curricula and to take advantage of new understandings in immunology. We have tried to achieve several goals and present the most important principles governing the function of the immune system. Our fundamental objective has been to synthesize the key concepts from the vast amount of experimental data that have emerged in the rapidly advancing field of immunology. The choice of what is most important is based on what is most clearly established by experimentation, what our students find puzzling, and what explains the wonderful efficiency and economy of the immune system. Inevitably, however, such a choice will have an element of bias, and our bias is toward emphasizing the cellular interactions in immune response by limiting the description of many of the underlying biochemical and molecular mechanisms to the essential facts. This book gives an insight into the role of cytokines in activating immune response during pathogenic invasion. Immunomodulation, aryl hydrocarbons, the role of the protein defensin and nucleated cells in provoking immune response, Bcl protein/gene-based apoptotic pathways, and plant-derived phytochemical-mediated immune response are all central themes of this book.
Book Synopsis Innate Immune Cell Recruitment and Host Defense in Response to Intracellular Bacterial Infection by : William Jerome Bunce Vincent
Download or read book Innate Immune Cell Recruitment and Host Defense in Response to Intracellular Bacterial Infection written by William Jerome Bunce Vincent and published by . This book was released on 2017 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interactions between invading pathogens and host immune cells that respond to infection is a long and involved relationship. In particular, a class of pathogens have evolved to not only evade clearance by the cells of the innate immune system, but do so by manipulation of the host cytosol. This proximity has led to the intricate co-evolution of clearance and evasion mechanisms of the host and pathogen, respectively. How these interactions are carried out in the cellular immune response is the subject of this dissertation. In Chapter 2, I build a localized infection model for one such pathogen, Listeria monocytogenes, using the transparent zebrafish larval host. Using this model, I demonstrate the functional presence of a conserved innate immune sensing pathway, the inflammasome, that surveils the cytosol for the presence of bacterial flagellin. Upon optimal inflammasome activation, the host is protected from lethal infection, and I show that macrophages are the crucial host cell population in this defense. In Chapter 3, I characterize L. monocytogenes' utilization of the host actin network demonstrating live imaging of this interaction for the first time in vivo. Once L. monocytogenes is localized within the cytosol, it slows down macrophage motility, although in an actin independent manner. In Chapter 4, I develop a model to study the recruitment and resolution of leukocytes during concurrent wounding and infection. This model demonstrates both beneficial and detrimental leukocyte responses, and provides evidence that the immune responses to bacterial infection and wounding are separable programs during early stages of immune response. Taken together, I have shown that macrophages are a crucial part of host defense downstream of inflammasome activation, that macrophages activate other cell autonomous responses during their interaction with intracellular pathogens, and that macrophage-neutrophil interactions can be critical in determining a beneficial or detrimental response to infection. These findings highlight the intricate and close evolution of host immune cells and intracellular pathogens, as well as the critical nature of inflammatory balance during immune responses.
Book Synopsis Immunomodulation of Innate Immune Cells by : Catarina R. Almeida
Download or read book Immunomodulation of Innate Immune Cells written by Catarina R. Almeida and published by Frontiers Media SA. This book was released on 2020-03-23 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Understanding and Exploiting Host-Commensal Interactions to Combat Pathogens by : Sudhanshu Shekhar
Download or read book Understanding and Exploiting Host-Commensal Interactions to Combat Pathogens written by Sudhanshu Shekhar and published by Frontiers Media SA. This book was released on 2020-01-14 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trillions of commensal microbes reside on and inside the human body, including the intestinal and respiratory tracts, which encompass various microbial taxa, such as bacteria, fungi, archea and viruses. The close proximity of microbes with the host provides an opportunity to continually interact with each other. Advances in research approaches, including high-throughput sequencing, have allowed us to study host and commensal microbes at the genetic and functional levels. Recent studies suggest that commensal microbes play a crucial role in the development of the host’s immune system and induce innate and adaptive immune responses against pathogens. It is also becoming apparent that the gut commensals are endowed with a capacity to alter immune responses in organs beyond the intestine, such as the lungs, highlighting the significance of the gut commensals in controlling systemic immunity. On the other hand, the host’s immune system possesses the ability to shape the repertoire of commensal microbes and contribute to the establishment of beneficial relationships with them. A better understanding of host-commensal interactions will be important for designing effective vaccines and therapeutics against pathogens. This Research Topic sheds light on our current understanding of the interplay between the host’s immune system and commensal microbes and how this interplay can be exploited for prophylactic and/or therapeutic strategies against pathogens.
Book Synopsis Chimpanzees in Biomedical and Behavioral Research by : National Research Council
Download or read book Chimpanzees in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2011-12-05 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.
Book Synopsis Host Defense Against Intracellular Pathogens by : Belinda Hsiu Jung Tan
Download or read book Host Defense Against Intracellular Pathogens written by Belinda Hsiu Jung Tan and published by . This book was released on 2004 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Host Defense and Infection by : Labro
Download or read book Host Defense and Infection written by Labro and published by CRC Press. This book was released on 1994-07-12 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spotlighting the recent development of antimicrobial molecules with immunomodulatory properties, this unique reference presents a detailed description of natural antimicrobial host defenses and elucidates how anti-infectious agents modulate the various effectors involved in combating environmental pathogens Reveals how Cefodizime (the only antibacterial drug to modulate the immune system in multiple ways) restores some impaired defense systems of the body, complementing its antibiotic activity. Investigating the biochemical interactions between antimicrobial agents and the immune system, Host Defense and Infection discusses innate versus specific immunity delineates the phagocytic destruction of pathogens and other functions of phagocytes examines cell effectors involved in nonspecific immune defenses, including natural and lymphocyte activated killer cells and mast cells analyzes the complement system of proteins that work to eliminate microorganisms and other antigens from tissues and blood considers various immune deficiencies and their infectious consequences covers the functional and chronobiological rhythms of immune defense summarizes important concepts of antimicrobial defense in numerous tables and schematic diagrams and more!
Book Synopsis Advances in The Immunology of Host Defense Peptide: Mechanisms and Applications of Antimicrobial Functions and Beyond by : Mark Hulett
Download or read book Advances in The Immunology of Host Defense Peptide: Mechanisms and Applications of Antimicrobial Functions and Beyond written by Mark Hulett and published by Frontiers Media SA. This book was released on 2021-04-07 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Trained Immunity-based Vaccines by : Jose Luis Subiza
Download or read book Trained Immunity-based Vaccines written by Jose Luis Subiza and published by Frontiers Media SA. This book was released on 2021-08-25 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Jose Luis Subiza is the founder and CEO of Inmunotek SL. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Book Synopsis Producing, sensing and responding to cellular stress in immunity by : Heitor A. Paula-Neto
Download or read book Producing, sensing and responding to cellular stress in immunity written by Heitor A. Paula-Neto and published by Frontiers Media SA. This book was released on 2019-11-28 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular stress, being considered as any disturbance in cellular physiology, is a fundamental aspect of tissue and body capacity to adapt to the ever changing environment. It also surges as a consequence of tissue injury or invasion of the body by pathogens. Since the immune system was developed to sense and respond to these deleterious processes, it is reasonable to consider that immune cells are capable of sensing and responding to signs of cellular stress. Moreover, cells of the immune system undergo cellular stress during an immune response. This Research Topic presents a series of articles focusing on how cellular stress influences the outcome of immune responses, covering not only how cellular stress can be a fundamental process during immune cell activation and function, but also how cells of the immune system are capable of sensing and being influenced by factors produced by stressed cells.
Book Synopsis Host Defenses to Intracellular Pathogens by :
Download or read book Host Defenses to Intracellular Pathogens written by and published by . This book was released on 1983 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Nijkamp and Parnham's Principles of Immunopharmacology by : Michael J. Parnham
Download or read book Nijkamp and Parnham's Principles of Immunopharmacology written by Michael J. Parnham and published by Springer Nature. This book was released on 2019-12-10 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The 4th edition of this internationally recognized textbook has been revised to include recent developments, but continues the established format, dealing with four related fields in a single volume, thus obviating the need to refer to several different textbooks. The first section of the book, providing a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts, particularly the role of epigenetics and the latest understanding of cancer immunology. The second section on immunodiagnostics offers a topical description of widely used molecular techniques and a new chapter on imaging techniques. This is followed by a systematic coverage of drugs affecting the immune system, including natural products. This third section contains 15 updated chapters, covering classical immunopharmacological topics such as anti-asthmatic, anti-rheumatic and immunosuppressive drugs, but also deals with antibiotics, plant-derived and dietary agents, with new chapters on monoclonal antibodies, immunotherapy in sepsis and infection, drugs for soft-tissue autoimmunity and cell therapy. The book concludes with a chapter on immunotoxicology and drug safety tests. Aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first three editions. The book is a valuable single reference for undergraduate and graduate medical and biomedical students, postgraduate chemistry and pharmacy students, researchers in chemistry, biochemistry and the pharmaceutical industry and researchers lacking basic immunological knowledge, who want to understand the actions of drugs on the immune system.
Book Synopsis Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases by : Institute of Medicine
Download or read book Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-01 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: A single tick bite can have debilitating consequences. Lyme disease is the most common disease carried by ticks in the United States, and the number of those afflicted is growing steadily. If left untreated, the diseases carried by ticks-known as tick-borne diseases-can cause severe pain, fatigue, neurological problems, and other serious health problems. The Institute of Medicine held a workshop October 11-12, 2010, to examine the state of the science in Lyme disease and other tick-borne diseases.
