Horizons In Clinical Nanomedicine

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Horizons in Clinical Nanomedicine

Author : Varvara Karagkiozaki
Publisher : CRC Press
ISBN 13 : 9814411566
Total Pages : 374 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Horizons in Clinical Nanomedicine by : Varvara Karagkiozaki

Download or read book Horizons in Clinical Nanomedicine written by Varvara Karagkiozaki and published by CRC Press. This book was released on 2014-10-28 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomedicine—the application of nanotechnology to health sciences—has the potential to address many important medical problems by exploiting the advanced physicochemical characteristics of nanostructured materials and devices. It can revolutionize conventional medicine by offering cutting-edge developments in the processes of diagnosing, treating, and preventing diseases, injuries, or genetic disorders. Thus, clinical nanomedicine holds promise to preserve and improve human health. This book provides a comprehensive overview on the forefront developments of nanotechnology in various domains of clinical medicine, such as cardiology, oncology, pharmacology, immunology, dermatology, virology, hematology, orthopedics, embryology and congenital defects, dentistry, and tissue engineering. It also extensively discusses the toxicology aspects of engineered nanomaterials.

Horizons in Clinical Nanomedicine

Author : Varvara Karagkiozaki
Publisher : CRC Press
ISBN 13 : 9814411574
Total Pages : 364 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Horizons in Clinical Nanomedicine by : Varvara Karagkiozaki

Download or read book Horizons in Clinical Nanomedicine written by Varvara Karagkiozaki and published by CRC Press. This book was released on 2014-10-28 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomedicine-the application of nanotechnology to health sciences-has the potential to address many important medical problems by exploiting the advanced physicochemical characteristics of nanostructured materials and devices. It can revolutionize conventional medicine by offering cutting-edge developments in the processes of diagnosing, treating,

Handbook of Clinical Nanomedicine

Author : Raj Bawa
Publisher : CRC Press
ISBN 13 : 9814669237
Total Pages : 1472 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis Handbook of Clinical Nanomedicine by : Raj Bawa

Download or read book Handbook of Clinical Nanomedicine written by Raj Bawa and published by CRC Press. This book was released on 2016-04-27 with total page 1472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique handbook (60 chapters) examines the entire "product life cycle," from the creation of nanomedical products to their final market introduction. While focusing on critical issues relevant to nanoproduct development and translational activities, it tackles topics such as regulatory science, patent law, FDA law, ethics, personalized medicin

Dendrimers in Nanomedicine

Author : Delphine Felder-Flesch
Publisher : CRC Press
ISBN 13 : 9814745502
Total Pages : 424 pages
Book Rating : 4.8/5 (147 download)

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Book Synopsis Dendrimers in Nanomedicine by : Delphine Felder-Flesch

Download or read book Dendrimers in Nanomedicine written by Delphine Felder-Flesch and published by CRC Press. This book was released on 2016-10-26 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomedicine can take advantage of the recent developments in nanobiotechnology research for the creation of platforms with superior drug carrier capabilities, selective responsiveness to the environment, unique contrast enhancement profiles, and improved accumulation at the disease site. This book provides a broad glimpse of how various dendritic nanomaterials have been designed and used as efficient tools for nanomedicine. It comprises a pedagogic introduction to dendrimers and hyperbranched systems and their classical and accelerated syntheses through cutting-edge methodologies. The chapters on dendronized magnetic nanoparticles as theranostics, dendrimers in theory (molecular simulations), siRNA delivery with dendrimers, and dendrimers for image-guided therapy, combined with chapters focused on specific types of dendrimers or hyperbranched structures, detail the cutting-edge research in nanomedicine. Finally, a detailed chapter on issues related to the pharmacokinetics and biodistribution of dendrimers helps choose the right structures for successful transfer from bench to bedside. This book will appeal to those involved in nanobiotechnology, macromolecular science, cancer therapy, tissue repair, and siRNA delivery research.

The Nanotechnology Revolution

Author : Dale A. Stirling
Publisher : CRC Press
ISBN 13 : 1351617230
Total Pages : 202 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis The Nanotechnology Revolution by : Dale A. Stirling

Download or read book The Nanotechnology Revolution written by Dale A. Stirling and published by CRC Press. This book was released on 2018-01-17 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology is changing the world in a very big way, but at the atomic and sub-atomic level. Although the roots of nanotechnology can be traced back to more than a century ago, the last three decades have witnessed an explosion of nano-based technologies and products. This reference work examines the history, current status, and future directions of nanotechnology through an exhaustive search of the technical and scientific literature. The more than 4000 bibliographic citations it includes are carefully organized into core subject areas, and a geographic and subject index allows readers to quickly locate documents of interest. Although a sense of the global reach and interest in nanotechnology can be gleaned from the reference sections of countless journal articles, conference papers, and books, this is the only reference work providing an in-depth global perspective that is ready-made for nanotechnology professionals and those interested in learning more about all things nanotechnology. Despite the abundance of online resources, there is still an urgent need for well-researched, well-presented, concise, and thematically organized reference works. Instead of relying on wiki pages, citation aggregators, and related websites, the author searched the databases and databanks of scholarly literature search providers such as EBSCO, ProQuest, PUBMED, STN International, and Thomson Reuters. In addition, he used select serials-related databases to account for pertinent documents from countries in which English is not the primary national language (i.e., China Online Journals, e-periodica, J-STAGE, and SciELO Brazil among others).

Nanotechnologies in Preventive and Regenerative Medicine

Author : Vuk Uskokovic
Publisher : Elsevier
ISBN 13 : 0323480640
Total Pages : 618 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Nanotechnologies in Preventive and Regenerative Medicine by : Vuk Uskokovic

Download or read book Nanotechnologies in Preventive and Regenerative Medicine written by Vuk Uskokovic and published by Elsevier. This book was released on 2017-10-30 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnologies in Preventative and Regenerative Medicine demonstrates how control at the nanoscale can help achieve earlier diagnoses and create more effective treatments. Chapters take a logical approach, arranging materials by their area of application. Biomaterials are, by convention, divided according to the area of their application, with each chapter outlining current challenges before discussing how nanotechnology and nanomaterials can help solve these challenges This applications-orientated book is a valuable resource for researchers in biomedical science who want to gain a greater understanding on how nanotechnology can help create more effective vaccines and treatments, and to nanomaterials researchers seeking to gain a greater understanding of how these materials are applied in medicine. - Demonstrates how nanotechnology can help achieve more successful diagnoses at an earlier stage - Explains how nanomaterials can be manipulated to create more effective drug treatments - Offers suggestions on how the use of nanotechnology might have future applications to create even more effective treatments

Nanotechnology in Medicine

Author : Mahendra Rai
Publisher : John Wiley & Sons
ISBN 13 : 1119769884
Total Pages : 448 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Nanotechnology in Medicine by : Mahendra Rai

Download or read book Nanotechnology in Medicine written by Mahendra Rai and published by John Wiley & Sons. This book was released on 2021-10-19 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: NANOTECHNOLOGY IN MEDICINE Discover thorough insights into the toxicology of nanomaterials used in medicine In Nanotechnology in Medicine: Toxicity and Safety, an expert team of nanotechnologists delivers a robust and up-to-date review of current and future applications of nanotechnology in medicine with a special focus on neurodegenerative diseases, cancer, diagnostics, nano-nutraceuticals, dermatology, and gene therapy. The editors offer resources that address nanomaterial safety, which tends to be the greatest hurdle to obtaining the benefits of nanomedicine in healthcare. The book is a one-stop resource for recent and comprehensive information on the toxico logical and safety aspects of nanotechnology used in human health and medicine. It provides readers with cutting-edge techniques for delivering therapeutic agents into targeted cellular compartments, cells, tissues, and organs by using nanoparticulate carriers. The book also offers methodological considerations for toxicity, safety, and risk assessment. Nanotechnology in Medicine: Toxicity and Safety also provides readers with: A thorough introduction to the nanotoxicological aspects of nanomedicine, including translational nanomedicine and nanomedicine personalization Comprehensive introductions to nanoparticle toxicity and safety, including selenium nanoparticles and metallic nanoparticles Practical discussions of nanotoxicology and drug delivery, including gene delivery using nanocarriers and the use of nanomaterials for ocular delivery applications In-depth examinations of nanotechnology ethics and the regulatory framework of nanotechnology and medicine Perfect for researchers, post-doctoral candidates, and specialists in the fields of nanotechnology, nanomaterials, and nanocarriers, Nanotechnology in Medicine: Toxicity and Safety will also prove to be an indispensable part of the libraries of nanoengineering, nanomedicine, and biopharmaceutical professionals and nanobiotechnologists.

Nano-Pharmacokinetics and Theranostics

Author : Nanasaheb D. Thorat
Publisher : Elsevier
ISBN 13 : 0323850502
Total Pages : 324 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Nano-Pharmacokinetics and Theranostics by : Nanasaheb D. Thorat

Download or read book Nano-Pharmacokinetics and Theranostics written by Nanasaheb D. Thorat and published by Elsevier. This book was released on 2021-07-30 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy addresses from a comprehensive and multidisciplinary approach the translational aspects and clinical perspectives of nano-pharmacokinetics using cancer as a model disease. Nano-pharmacokinetics is emerging as an important sub discipline of nanoscience and medical sciences because of the increasing safety issues of nanosystems on living organisms. This book reports the dynamics of nanosystems in living organisms for better understanding of nanotoxicity, pharmacology, biochemistry, physiology and medicine perspectives. It further examines current progress of state-of-the art pharmacokinetics mechanisms, which will be of great help to develop more clinical-oriented nanosystems with a wide safety margin. The book is divided into three sections: the first section focuses on the concept of pharmacokinetics with state-of-the-art Nano-Pharmacokinetics (NPK). The second section looks at the engineering of nanoparticles and pharmacokinetics clinical development. The final section focuses on Nano-Pharmacokinetics and Theranostics, elaborating the basic question of how pharmacokinetics of nanomaterials relate to their end applications such as cancer therapy. Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy will be useful to researchers in the field of nanoparticle based targeted drug delivery including pharmaceutical scientists, material scientists, chemists, nanotechnologists, biomedical scientists, and clinicians. Includes contributions from highly qualified scientists, regulatory entities, enterprises and medical practitioners to explain the long and inherently multidisciplinary pathway of nano-pharmacokinetics Describes assessment methods of nano-pharmacokinetics Examines the interface between nanomedicine and pharmacokinetics to diagnose and treat cancer

Biodegradable and Biocompatible Polymer Nanocomposites

Author : Kalim Deshmukh
Publisher : Elsevier
ISBN 13 : 0323985599
Total Pages : 793 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Biodegradable and Biocompatible Polymer Nanocomposites by : Kalim Deshmukh

Download or read book Biodegradable and Biocompatible Polymer Nanocomposites written by Kalim Deshmukh and published by Elsevier. This book was released on 2023-04-10 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biodegradable and Biocompatible Polymer Nanocomposites: Processing, Characterization, and Applications brings together the latest research, highlighting cutting-edge applications in this exciting field. Sections introduce biodegradable and biocompatible polymers and the fundamentals regarding synthesis, structure, properties, biocompatibility and biodegradability, provide in-depth coverage of methods and techniques for processing, spectroscopic and microscopic analysis, dielectric, thermal, and electrical conductivity, and incorporation of functionalized nanoparticles, and green synthesized nanoparticles. The second part of the book guides the reader through the properties and preparation of biodegradable and biocompatible polymer nanocomposites for a range of specific, targeted, state-of-the-art applications across biomedicine, electronic, energy storage, environment and packaging. Finally, sustainability assessment, environmental impact, and recycling strategies are discussed in detail. - Provides detailed methods for green synthesis, polymer modification, processing and analysis - Explores novel applications across biomedicine, electronics, energy storage, the environment and packaging - Examines key issues, such as biocompatibility, biodegradability, recycling strategies and measuring environmental impact

Global Health Impacts of Nanotechnology Law

Author : Ilise L Feitshans
Publisher : CRC Press
ISBN 13 : 1351134450
Total Pages : 384 pages
Book Rating : 4.3/5 (511 download)

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Book Synopsis Global Health Impacts of Nanotechnology Law by : Ilise L Feitshans

Download or read book Global Health Impacts of Nanotechnology Law written by Ilise L Feitshans and published by CRC Press. This book was released on 2018-05-24 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Small things add up: trillions of dollars of products applying nanotechnology have been marketed to consumers promising new medicines, strong packaging to protect goods from contamination, stronger eyelash mascara and long-lasting lipstick, construction materials for housing, cheaper energy, and new drugs to fight cancer. Nanotechnology applications to consumer products represent a huge slice of daily economic life, heralding a revolutionary age for science and technology. How can the benefits of nanotechnology be realized while protecting public health? Global Health Impacts of Nanotechnology Law: A Tool for Stakeholder Engagement fills a major void in legal, scientific policy discourse about nanotechnology for people who are curious about nanoscience, bioethics, and law. The pioneering, plain-language text of Dr. Ilise L. Feitshans, international health law scholar and former international civil servant, enables readers to move comfortably across disciplines and explore how nanotechnology can reshape both commerce and public health to improve daily life worldwide.

Signaling Pathways in Developing and Pathological Tissues and Organs of the Craniofacial Complex

Author : Thimios Mitsiadis
Publisher : Frontiers Media SA
ISBN 13 : 2889456110
Total Pages : 281 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Signaling Pathways in Developing and Pathological Tissues and Organs of the Craniofacial Complex by : Thimios Mitsiadis

Download or read book Signaling Pathways in Developing and Pathological Tissues and Organs of the Craniofacial Complex written by Thimios Mitsiadis and published by Frontiers Media SA. This book was released on 2018-10-18 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Head formation requires the well-orchestrated and harmonised development of various tissues and organs within the craniofacial complex. A big variety of signaling pathways are involved in this process by controlling cell proliferation, migration, differentiation, tissue morphogenesis, homeostasis and regeneration. Deregulation and malfunction of these signaling molecules may lead to mild or severe craniofacial pathologies. This eBook is a collection of articles dealing with a variety of important signals involved in the control of developmental and pathological events of craniofacial organs and tissues. These recent advances show the importance of signaling pathways in craniofacial physiology and pathology and generate important new knowledge aiming the development of new pharmaceutical products that mimic and/or block the actions of specific molecules.

Triennial Review of the National Nanotechnology Initiative

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309447941
Total Pages : 149 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Triennial Review of the National Nanotechnology Initiative by : National Academies of Sciences, Engineering, and Medicine

Download or read book Triennial Review of the National Nanotechnology Initiative written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-01-12 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoscale science, engineering, and technology, often referred to simply as "nanotechnology," is the understanding, characterization, and control of matter at the scale of nanometers, the dimension of atoms and molecules. Advances in nanotechnology promise new materials and structures that are the basis of solutions, for example, for improving human health, optimizing available energy and water resources, supporting a vibrant economy, raising the standard of living, and increasing national security. Established in 2001, the National Nanotechnology Initiative (NNI) is a coordinated, multiagency effort with the mission to expedite the discovery, development, and deployment of nanoscale science and technology to serve the public good. This report is the latest triennial review of the NNI called for by the 21st Century Nanotechnology Research and Development Act of 2003. It examines and comments on the mechanisms in use by the NNI to advance focused areas of nanotechnology towards advanced development and commercialization and on the physical and human infrastructure needs for successful realization in the United States of the benefits of nanotechnology development.

Nanomaterials and Their Interactive Behavior with Biomolecules, Cells and Tissues

Author : Yogendrakumar H. Lahir
Publisher : Bentham Science Publishers
ISBN 13 : 9811461767
Total Pages : 404 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis Nanomaterials and Their Interactive Behavior with Biomolecules, Cells and Tissues by : Yogendrakumar H. Lahir

Download or read book Nanomaterials and Their Interactive Behavior with Biomolecules, Cells and Tissues written by Yogendrakumar H. Lahir and published by Bentham Science Publishers. This book was released on 2020-08-04 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoscience is a multidisciplinary area of science which enables researchers to create tools that help in understanding the mechanisms related to the interactions between nanomaterials and biomolecules (nanotechnology). Nanomaterials represent nanotechnology products. These products have an enormous impact on technical industries and the quality of human life. Nanomaterials directly or indirectly have to interact with biosystems. It is, therefore, essential to understand the beneficial and harmful interactions of nanomaterials with and within a biosystem, especially with reference to humans. This book provides primary and advanced information concerning the interactions between nanomaterials and the components of a typical biosystem to readers. Chapters in the book cover, in a topic-based approach, the many facets of nanomolecular interactions with biological molecules and systems that influence their behavior, bioavailability and biocompatibility (including nucleic acids, cell membranes, tissues, enzymes and antibodies). A note on the applications of nanomaterials is also presented in the conclusion of the book to illustrate the usefulness of this class of materials. The contents of the book will benefit students, researchers, and technicians involved in the fields of biological sciences, such as cell biology, medicine, molecular biology, food technology, cosmetology, pharmacology, biotechnology, and environmental sciences. The book also provides information for the material science personnel, enabling them to understand the basics of target-oriented nanomaterials design for specific objectives.

Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes

Author : Vijay Mishra
Publisher : Academic Press
ISBN 13 : 0128097183
Total Pages : 553 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes by : Vijay Mishra

Download or read book Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes written by Vijay Mishra and published by Academic Press. This book was released on 2017-05-23 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. By focusing on the design, synthesis, and application of a variety of nanocarriers in drug and gene delivery, this book provides pharmaceutical and materials science students, professors, clinical researchers, and industry scientists with a valuable resource aimed at tackling the challenges of delivering drugs and genes in a more targeted manner. - Explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advances in cutting-edge nanomedical technologies - Contains contributions from world-renowned experts and researchers working in the area of nanomedicine and drug delivery - Covers the associated challenges and potential solutions to working with nanotechnology in drug delivery - Highlights crucial topics, such as biopharmaceutical and toxicity issues, quality by design, drug targeting, and more

Nanomedicine

Author : Yi Ge
Publisher : Springer
ISBN 13 : 1461421403
Total Pages : 415 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Nanomedicine by : Yi Ge

Download or read book Nanomedicine written by Yi Ge and published by Springer. This book was released on 2014-12-01 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing demand for and awareness of the applications of nanotechnology in medicine has resulted in the emergence of a new fast-growing multidisciplinary area - nanomedicine. This book offers comprehensive knowledge of and diverse perspectives on nanomedicine through two independent volumes. It aims to bridge the gap between nanotechnology and medicine through contributions by world-renowned experts from wide range of backgrounds including academia, industry, professional consultancy, and government agencies. Each contribution integrates knowledge from a wide range of areas to present the fundamentals of new applications and products of nanomedicine, as well as an outlook for the future. This book can well serve as a reference and guide for students, academics, researchers, scientists, engineers, clinicians, government researchers, and healthcare professionals.

Nanotechnology and the Challenges of Equity, Equality and Development

Author : Susan E. Cozzens
Publisher : Springer Science & Business Media
ISBN 13 : 9048196159
Total Pages : 471 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Nanotechnology and the Challenges of Equity, Equality and Development by : Susan E. Cozzens

Download or read book Nanotechnology and the Challenges of Equity, Equality and Development written by Susan E. Cozzens and published by Springer Science & Business Media. This book was released on 2010-10-10 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology is enabling applications in materials, microelectronics, health, and agriculture, which are projected to create the next big shift in production, comparable to the industrial revolution. Such major shifts always co-evolve with social relationships. This book focuses on how nanotechnologies might affect equity/equality in global society. Nanotechnologies are likely to open gaps by gender, ethnicity, race, and ability status, as well as between developed and developing countries, unless steps are taken now to create a different outcome. Organizations need to change their practices, and cultural ideas must be broadened if currently disadvantaged groups are to have a more equal position in nano-society rather than a more disadvantaged one. Economic structures are likely to shift in the nano-revolution, requiring policymakers and participatory processes to invent new institutions for social welfare, better suited to the new economic order than those of the past.

RNA Delivery Function for Anticancer Therapeutics

Author : Loutfy H. Madkour
Publisher : CRC Press
ISBN 13 : 1000532232
Total Pages : 424 pages
Book Rating : 4.0/5 (5 download)

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Book Synopsis RNA Delivery Function for Anticancer Therapeutics by : Loutfy H. Madkour

Download or read book RNA Delivery Function for Anticancer Therapeutics written by Loutfy H. Madkour and published by CRC Press. This book was released on 2022-01-25 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of the current status of translating the RNAi cancer therapeutics in the clinic, a brief description of the biological barriers in drug delivery, and the roles of imaging in aspects of administration route, systemic circulation, and cellular barriers for the clinical translation of RNAi cancer therapeutics, and with partial content for discussing the safety concerns. It then focuses on imaging-guided delivery of RNAi therapeutics in preclinical development, including the basic principles of different imaging modalities, and their advantages and limitations for biological imaging. With growing number of RNAi therapeutics entering the clinic, various imaging methods will play an important role in facilitating the translation of RNAi cancer therapeutics from bench to bedside. RNAi technique has become a powerful tool for basic research to selectively knock down gene expression in vitro and in vivo. Our scientific and industrial communities have started to develop RNAi therapeutics as the next class of drugs for treating a variety of genetic disorders, such as cancer and other diseases that are particularly hard to address with current treatment strategies. Key Features Provides insight into the current advances and hurdles of RNAi therapeutics. Accelerates RNAi, miRNAs, and siRNA drug development for cancer therapy from bench to bedside. Addresses various modifications and novel delivery strategies for miRNAs, piRNAs and siRNA delivery in anticancer therapeutics. Explores the need for the interaction of hematologists,cell biologists, immunologists, and material scientists in the development of novel cancer therapies. Describes the current status of clinical trials related to miRNA and siRNA-based cancer therapy Presents remaining issues that need to be overcome to establish successful therapies.