Hiv Virology And Immunology

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HIV Protocols

Author : Nelson Michael
Publisher : Springer Science & Business Media
ISBN 13 : 1592596010
Total Pages : 402 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis HIV Protocols by : Nelson Michael

Download or read book HIV Protocols written by Nelson Michael and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The worldwide impact of infection with human immunodeficiency virus type 1 (HIV- is reflected in the cumulative number ofHIV- 1 infections, which is now predicted to exceed 40 million by the year 2000---equivalent to the n- ber of humans who perished in World War II. The medical and scientific - sponse to the HIV-1 pandemic has steadily grown since its recognition in 1981. The outlay by the United States alone for HIV research funded by the National Institutes of Health in 1997 was $1. 4 billion. Laboratory-based HIV research has brought together academic clinicians, retrovirologists, molecular biologists, and immunologists in the formation of research teams attempting to dissect the viral and host factors contributing to disease pathogenesis. Increasing focus is being placed on those aspects of viral biology and host immune responses that bear on the development of vaccines to prevent HIV infection. HIVProtocols reflects the state of HIV research in several ways. First, chapters are organized into four sections: Virology, Molecular Biology, Humoral Immunology, and Cellular Immunology. This organization is a natural consequence of the diverse scientific disciplines that have been attracted to HIV research. Second, the chapters reflect such diverse research directions as viral coreceptor usage, quantitation of viral genomes, HIV promoter function, B-cell epitope mapping, and measurements of T-cell function, each of which bears on the goal of understanding the viral and host immune responses that will be critical to the design of effective preventive vaccines.

The Human Immunodeficiency Virus

Author : Emilio Emini
Publisher : Princeton University Press
ISBN 13 : 0691228833
Total Pages : 546 pages
Book Rating : 4.6/5 (912 download)

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Book Synopsis The Human Immunodeficiency Virus by : Emilio Emini

Download or read book The Human Immunodeficiency Virus written by Emilio Emini and published by Princeton University Press. This book was released on 2021-04-13 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past few years have witnessed an explosive increase in our collective knowledge of the biology of the human immunodeficiency virus (HIV). Researchers have acquired new understanding of the virus's biochemistry, molecular biology, pathogenesis, genetics, and immunobiology. Resulting therapeutic advances have significantly prolonged the lives of thousands. Yet, the need to develop better therapies is ever more acute and--given the virus's continued spread through the human population--the need for an effective vaccine is urgent. These goals can be accomplished only through the experienced synthesis of information from the many disciplines participating in HIV research and through the insights of new investigators. This volume is designed to lower the barriers imposed on investigators by the sheer volume of available information--information that often can be found only in far-flung and specialized journals. It provides, in a single resource, an in-depth overview of the diverse areas that constitute HIV research. The result is a broad introduction for students and researchers new to the field as well as an integrated overview for researchers specialized in particular areas of HIV investigation. The volume will also benefit those seeking technical understanding of the virus's biology, including physicians treating HIV-infected patients. Each chapter is a comprehensive presentation of one area of current AIDS research--including work on the virus life cycle, epidemiology, genetics, protease and reverse transcriptase inhibitors, receptor and co-receptor interactions, therapeutic targets, clinical treatment, immunobiology, and vaccines--written by a leading researcher in that area. The contributors are Jon P. Anderson, Jan Balzarini, Elana Cherry, Thomas J. Coates, Chris Collins, Jon H. Condra, Mark B. Feinberg, Richard B. Gaynor, Matthias Götte, Daria J. Hazuda, Spyros Kalams, Nathaniel R. Landau, Gerald H. Learn, Norman L. Letvin, James I. Mullins, Willscott E. Naugler, David Nickle, Matthew Rain, Allen G. Rodrigo, Daniel Shriner, Shalom Spira, Mario Stevenson, Todd Summers, Catherine Ulich, Joseph P. Vacca, Mark A. Wainberg, Bruce D. Walker, and Yang Wang.

HIV: Virology and immunology

Author : Jonathan Karn
Publisher :
ISBN 13 : 9780199634934
Total Pages : 0 pages
Book Rating : 4.6/5 (349 download)

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Book Synopsis HIV: Virology and immunology by : Jonathan Karn

Download or read book HIV: Virology and immunology written by Jonathan Karn and published by . This book was released on 1995 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

HIV-1 Latency

Author : Guido Silvestri
Publisher : Springer
ISBN 13 : 303002816X
Total Pages : 248 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis HIV-1 Latency by : Guido Silvestri

Download or read book HIV-1 Latency written by Guido Silvestri and published by Springer. This book was released on 2018-10-11 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.

The Biology of Dendritic Cells and HIV Infection

Author : Sandra Gessani
Publisher : Springer Science & Business Media
ISBN 13 : 0387337857
Total Pages : 562 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis The Biology of Dendritic Cells and HIV Infection by : Sandra Gessani

Download or read book The Biology of Dendritic Cells and HIV Infection written by Sandra Gessani and published by Springer Science & Business Media. This book was released on 2007-03-09 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendritic cells play the most vital part in inducing anti-viral immune responses in HIV and AIDS among many other viruses. Research on dendritic cells (DCs) is emerging as a fundamental aspect for the comprehension of the mechanisms underlying the pathogenesis of viral diseases. This volume focuses on the role of DCs in the pathogenesis and immunity of HIV-1 infection. It is the only comprehensive volume on pathogenesis and immunity of Dendritic Cells that also focuses on HIV.

AIDS Pathogenesis

Author : H. Schuitemaker
Publisher : Springer Science & Business Media
ISBN 13 : 9401706859
Total Pages : 300 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis AIDS Pathogenesis by : H. Schuitemaker

Download or read book AIDS Pathogenesis written by H. Schuitemaker and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as the Acquired Immunodeficiency Syndrome (AIDS). The book AIDS Pathogenesis provides the reader with a complete overview of the clinical course of HIV-1 infection. It describes the clinical aspects of primary infection, the different clinical outcomes of HIV-1 infection, and strategies for anti-viral treatment. In addition, more fundamental aspects of HIV-1 infection are reviewed. These include the biology of the virus and the novel insights in AIDS pathogenesis. Not only is the significance of an HIV-specific cellular and humoral immune response discussed, but also the possible incapacity of the adult human host to deal with T-cell destruction. Finally, the book discusses the currently used laboratory markers that allow for monitoring of the clinical course of infection.

HIV Interactions with Dendritic Cells

Author : Li Wu
Publisher : Springer Science & Business Media
ISBN 13 : 1461444330
Total Pages : 303 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis HIV Interactions with Dendritic Cells by : Li Wu

Download or read book HIV Interactions with Dendritic Cells written by Li Wu and published by Springer Science & Business Media. This book was released on 2012-09-13 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given rapid research progress and advance of the techniques in studying HIV interactions with host cells and factors, there is a critical need for a book on HIV interactions with DCs. The proposed book will aim for a broad readership to facilitate HIV/AIDS research and provide a practical tool for HIV researchers to continuously address novel questions. Specifically, the editors will summarize the literature in this field and provide critical analysis and future directions. International researchers will be invited as contributors of the book, highlighting authors who have contributed significantly to the field from different angles and aspects of virology, cell biology and immunology, etc.

Fundamentals of HIV Medicine

Author : William David Hardy
Publisher : Oxford University Press
ISBN 13 : 0190493097
Total Pages : 617 pages
Book Rating : 4.1/5 (94 download)

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Book Synopsis Fundamentals of HIV Medicine by : William David Hardy

Download or read book Fundamentals of HIV Medicine written by William David Hardy and published by Oxford University Press. This book was released on 2017-04-18 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely updated for 2017, Fundamentals of HIV Medicine is a comprehensive clinical care publication for the treatment of HIV/AIDS. Published by the American Academy of HIV Medicine, the book offers physicians, pharmacists, nurse practitioners, and other care providers the most up-to-date overview of the latest HIV treatments and guidelines plus online access to CME. The online access expires August 2018. Embodying the AAHIVM's commitment to promoting uniform excellence in care of seropositive patients, Fundamentals of HIV Medicine 2017 empowers health professionals to deliver standardized, life-sustaining treatment to the patients who need it most. It will serve as an essential clinical reference and provide valuable career enrichment to users across the spectrum of HIV care, treatment, and prevention.

Immunology of HIV Infection

Author : Gr. Bird
Publisher : Springer Science & Business Media
ISBN 13 : 9401129800
Total Pages : 187 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Immunology of HIV Infection by : Gr. Bird

Download or read book Immunology of HIV Infection written by Gr. Bird and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is now 10 years since the first AIDS cases were reported in the USA. In that relatively short period of time, study of the disease has moved from the level of early clinical description to exhaustive and extensive laboratory characterization of the human immunodeficiency virus (HIV), the immune responses directed towards it and reasons for their failure. This volume provides contributions from clinical and basic scientists who are actively involved in research in a number of areas of current interest and controversy. Further progress in the clinical management of the HIV-infected patient will undoubtedly build on the basic knowledge about HIV and its modes of pathogenesis. The intimate relationship between HIV and the human immune system provides observations and questions that are relevant to viral immunopathogenesis in general. In the first chapter the clinical features of HIV immunodeficiency are re viewed, and aspects of its changing face are discussed. Dr Tersmette then presents evidence for changing viral characteristics at different stages of the disease. This view of close competition for ascendancy between HIV and the host immune response raises questions about current approaches to therapy.

Global Virology II - HIV and NeuroAIDS

Author : Paul Shapshak
Publisher : Springer
ISBN 13 : 1493972901
Total Pages : 1067 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Global Virology II - HIV and NeuroAIDS by : Paul Shapshak

Download or read book Global Virology II - HIV and NeuroAIDS written by Paul Shapshak and published by Springer. This book was released on 2017-10-07 with total page 1067 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on NeuroAIDS, a collection of chapters written by experts and specialists from around the world, provides a global perspective on HIV and NeuroAIDS in the field, clinic, and laboratory. The chapters address the comorbidity of HIV and other infectious agents, including Zika virus, Ebola, Chagas disease, TB and HCV. Also discussed are key topics, such as: · Molecular socioepidemiology · Global HIV and NeuroAIDS · Neuropathology · cART and blood-brain barrier penetration · HIV replicative oscillations · HIV and SIV evolution · Psychiatric comorbidities · Neurosyphilis · The examination of current and innovative models of translational research to translational effectiveness

Immunopathogenesis of HIV Infection

Author : Anthony S. Fauci
Publisher : Springer Science & Business Media
ISBN 13 : 3642608671
Total Pages : 159 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Immunopathogenesis of HIV Infection by : Anthony S. Fauci

Download or read book Immunopathogenesis of HIV Infection written by Anthony S. Fauci and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last 5 years, major advances have been made in our understanding of the pathogenesis of human immunodeficiency virus (HIV) disease and in the development of new potent antiviral agents. With regard to HIV pathogenesis, several recent observations have not only changed our perspectives of HIV disease, but have been critical for the design of therapeutic strategies.

HIV: Volume 1: Virology and Immunology

Author : Jonathan Karn
Publisher : IRL Press
ISBN 13 : 9780199634927
Total Pages : 302 pages
Book Rating : 4.6/5 (349 download)

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Book Synopsis HIV: Volume 1: Virology and Immunology by : Jonathan Karn

Download or read book HIV: Volume 1: Virology and Immunology written by Jonathan Karn and published by IRL Press. This book was released on 1995-11-09 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: AIDS is undeniably one of the most pressing medical emergencies of our era but it is now 12 years since the discovery of HIV and, in spite of a world-wide research effort, we are still a long way from understanding and controlling AIDS. HIV 1: A Practical Approach describes studies of the virus and infected cells. Together with its companion volume, HIV 2, which explores the biochemistry of HIV, it provides clear, practical instructions about how to study HIV in the laboratory.

Immunology and Evolution of Infectious Disease

Author : Steven A. Frank
Publisher : Princeton University Press
ISBN 13 : 9780691095950
Total Pages : 364 pages
Book Rating : 4.0/5 (959 download)

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Book Synopsis Immunology and Evolution of Infectious Disease by : Steven A. Frank

Download or read book Immunology and Evolution of Infectious Disease written by Steven A. Frank and published by Princeton University Press. This book was released on 2002-07-21 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description

Virus Dynamics : Mathematical Principles of Immunology and Virology

Author : Martin Nowak
Publisher : Oxford University Press, UK
ISBN 13 : 0191588512
Total Pages : 253 pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis Virus Dynamics : Mathematical Principles of Immunology and Virology by : Martin Nowak

Download or read book Virus Dynamics : Mathematical Principles of Immunology and Virology written by Martin Nowak and published by Oxford University Press, UK. This book was released on 2000-11-23 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This groundbreaking book describes the emerging field of theoretical immunology, in particular the use of mathematical models to describe the spread of infectious diseases within patients. It reveals fascinating insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. Structured around the examples of HIV/AIDS and hepatitis B, Nowak and May show how mathematical models can help researchers to understand the detailed dynamics of infection and the effects of antiviral therapy. Models are developed to describe the dynamics of drug resistance, immune responses, viral evolution and mutation, and to optimise the design of therapy and vaccines. - ;We know, down to the tiniest details, the molecular structure of the human immunodeficiency virus (HIV). Yet despite this tremendous accomplishment, and despite other remarkable advances in our understanding of individual viruses and cells of the immune system, we still have no agreed understanding of the ultimate course and variability of the pathogenesis of AIDS. Gaps in our understanding like these impede our efforts towards developing effective therapies and preventive vaccines. Martin Nowak and Robert M May describe the emerging field of theoretical immunology in this accessible and well- written text. Using mathematical modelling techniques, the authors set out their ideas about how populations of viruses and populations of immune system cells may interact in various circumstances, and how infectious diseases spread within patients. They explain how this approach to understanding infectious diseases can reveal insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. The book is structured around the examples of HIV/AIDS and Hepatitis B virus, although the approaches described will be more widely applicable. The authors use mathematical tools to uncover the detailed dynamics of the infection and the effects of antiviral therapy. Models are developed to describe the emergence of drug resistance, and the dynamics of immune responses, viral evolution, and mutation. The practical implications of this work for optimisation of the design of therapy and vaccines are discussed. The book concludes with a glance towards the future of this fascinating, and potentially highly useful, field of study. - ;... an excellent introduction to a field that has the potential to advance substantially our understanding of the complex interplay between virus and host - Nature

HIV Vaccines and Cure

Author : Linqi Zhang
Publisher : Springer
ISBN 13 : 981130484X
Total Pages : 318 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis HIV Vaccines and Cure by : Linqi Zhang

Download or read book HIV Vaccines and Cure written by Linqi Zhang and published by Springer. This book was released on 2018-07-20 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry.

Virus Dynamics

Author : Martin A. Nowak
Publisher : Oxford University Press
ISBN 13 : 0198504179
Total Pages : 253 pages
Book Rating : 4.1/5 (985 download)

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Book Synopsis Virus Dynamics by : Martin A. Nowak

Download or read book Virus Dynamics written by Martin A. Nowak and published by Oxford University Press. This book was released on 2000-11-23 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text describes the emerging field of theoretical immunology, in particular the use of mathematical models to describe the spread of infectious diseases within patients. It reveals insights into the dynamics of viral & other infections.

Advances in HIV-1 Assembly and Release

Author : Eric O. Freed
Publisher : Springer Science & Business Media
ISBN 13 : 1461477298
Total Pages : 229 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Advances in HIV-1 Assembly and Release by : Eric O. Freed

Download or read book Advances in HIV-1 Assembly and Release written by Eric O. Freed and published by Springer Science & Business Media. This book was released on 2013-07-12 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, enormous progress has been made in understanding the late events in the HIV replication cycle. This has been made possible by major advances in cell biology, virology, and structural biology. The field continues to move forward rapidly, with important new discoveries being reported on a regular basis. The impact of this progress across a broad spectrum of biomedical research has been substantial. The increase in basic knowledge in the areas of HIV assembly, release, and maturation has been accompanied by new possibilities for therapeutic intervention.The work includes topics relating to basic molecular biology, cell biology, and structural biology of HIV assembly, coupled with more applied ideas of how this basic information can inform the field of antiretroviral research. The book covers all major topics pertaining to the late stages of HIV replication, with leaders in each area recruited to contribute chapters in their areas of expertise . The topics will be sufficiently focused to allow authors the opportunity to cover the latest developments in detail.