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Hemostasis Biomarkers In The Prognosis Of Non Traumatic Intracerebral Hemorrhage
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Book Synopsis HEMOSTASIS BIOMARKERS IN THE PROGNOSIS OF NON-TRAUMATIC INTRACEREBRAL HEMORRHAGE by : Judit Tóth
Download or read book HEMOSTASIS BIOMARKERS IN THE PROGNOSIS OF NON-TRAUMATIC INTRACEREBRAL HEMORRHAGE written by Judit Tóth and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction and Objectives. Non-traumatic intracerebral hemorrhage (ICH) accounts for 10-15% of all strokes and results in higher rate of mortality as compared to ischemic strokes. In the IRONHEART study we aimed to find potential hemostasis biomarkers with prognostic value in patients with ICH.Patients and methods. In this prospective, observational study, 183 acute stroke patients and 140 healthy controls were included. Patients were grouped: 51 primary ICH patients (PICH), 118 acute ischemic stroke patients who underwent thrombolysis without hemorrhagic events (AIS), 13 patients with AIS who suffered hemorrhagic complications after intravenous thrombolysis (AIS-ICH). On admission, CT angiography, detailed clinical and laboratory investigations were performed. The following hemostasis measurements were carried out from blood samples: hemostasis screening tests, von Willebrand factor (VWF) antigen, factor XIII (FXIII), plasminogen and uf0612 antiplasmin activity, D-dimer. Patients were followed for 90 days, long term outcomes were defined using the modified Rankin Scale. Results. VWF level was significantly higher in all patient groups as compared to controls. VWF levels were significantly higher in patients with worse long-term outcomes (mRS>3) in all patient cohorts. FXIII activity was significantly elevated in the PICH group as compared to controls and to both AIS groups. FXIII activity in the lowest quartile was associated with a significant risk of mortality in the PICH group (OR: 9.9; 95%CI:1.6-61.6, p=0.015). Among fibrinolytic markers, only D-dimer showed association with worse long-term outcomes (mRS>3).Conclusion.VWF antigen, FXIII activity and D-dimer could serve as biomarkers of long-term outcomes in PICH patients. Funding: GINOP-2.3.2-15-2016-00043, NKFI-K120042.
Book Synopsis HEMOSTASIS BIOMARKERS IN THE PROGNOSIS OF NON-TRAUMATIC INTRACEREBRAL HEMORRHAGE by : Judit Tu00f3th
Download or read book HEMOSTASIS BIOMARKERS IN THE PROGNOSIS OF NON-TRAUMATIC INTRACEREBRAL HEMORRHAGE written by Judit Tu00f3th and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction and Objectives. Non-traumatic intracerebral hemorrhage (ICH) accounts for 10-15% of all strokes and results in higher rate of mortality as compared to ischemic strokes. In the IRONHEART study we aimed to find potential hemostasis biomarkers with prognostic value in patients with ICH.Patients and methods. In this prospective, observational study, 183 acute stroke patients and 140 healthy controls were included. Patients were grouped: 51 primary ICH patients (PICH), 118 acute ischemic stroke patients who underwent thrombolysis without hemorrhagic events (AIS), 13 patients with AIS who suffered hemorrhagic complications after intravenous thrombolysis (AIS-ICH). On admission, CT angiography, detailed clinical and laboratory investigations were performed. The following hemostasis measurements were carried out from blood samples: hemostasis screening tests, von Willebrand factor (VWF) antigen, factor XIII (FXIII), plasminogen and uf0612 antiplasmin activity, D-dimer. Patients were followed for 90 days, long term outcomes were defined using the modified Rankin Scale. Results. VWF level was significantly higher in all patient groups as compared to controls. VWF levels were significantly higher in patients with worse long-term outcomes (mRS>3) in all patient cohorts. FXIII activity was significantly elevated in the PICH group as compared to controls and to both AIS groups. FXIII activity in the lowest quartile was associated with a significant risk of mortality in the PICH group (OR: 9.9; 95%CI:1.6-61.6, p=0.015). Among fibrinolytic markers, only D-dimer showed association with worse long-term outcomes (mRS>3).Conclusion.VWF antigen, FXIII activity and D-dimer could serve as biomarkers of long-term outcomes in PICH patients. Funding: GINOP-2.3.2-15-2016-00043, NKFI-K120042.
Book Synopsis Diseases of the Brain, Head and Neck, Spine 2020–2023 by : Juerg Hodler
Download or read book Diseases of the Brain, Head and Neck, Spine 2020–2023 written by Juerg Hodler and published by Springer Nature. This book was released on 2020-02-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.
Book Synopsis Textbook of Stroke Medicine by : Michael Brainin
Download or read book Textbook of Stroke Medicine written by Michael Brainin and published by Cambridge University Press. This book was released on 2014-09-11 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised throughout, the new edition of this concise textbook is aimed at doctors preparing to specialize in stroke care.
Book Synopsis Trauma Induced Coagulopathy by : Hunter B. Moore
Download or read book Trauma Induced Coagulopathy written by Hunter B. Moore and published by Springer Nature. This book was released on 2020-10-12 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.
Book Synopsis Biomarkers in Trauma, Injury and Critical Care by : Rajkumar Rajendram
Download or read book Biomarkers in Trauma, Injury and Critical Care written by Rajkumar Rajendram and published by Springer Nature. This book was released on 2023-03-22 with total page 1203 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook systematically presents biomarkers for traumatic injuries. The book covers topics such as traumatic brain injury, liver injury, burn severity, muscle heart damage, and acute inflammation in polytrauma and their detection by biomarkers. Biomarkers and methods used in critical care and critically ill patients are discussed, as well as biomarkers in trauma and special conditions. Specific biomarker components are explained and models for modeling trauma in research are presented. This systematic handbook is an excellent resource for researchers and specialists in trauma research and treatment, as well as clinicians and physicians who want a thorough overview of various injuries, trauma, and their detection methods.
Book Synopsis Hemostasis and Stroke by : Zsuzsa Bagoly
Download or read book Hemostasis and Stroke written by Zsuzsa Bagoly and published by Frontiers Media SA. This book was released on 2021-09-30 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biomarkers for Traumatic Brain Injury by : Svetlana Dambinova
Download or read book Biomarkers for Traumatic Brain Injury written by Svetlana Dambinova and published by Royal Society of Chemistry. This book was released on 2012 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to injuries sustained in sports and in combat, interest in traumatic brain injury (TBI) has never been greater. This book will fulfill a gap in understanding of what is occurring in the brain following injury that can subsequently be detected in biological fluids and imaging.
Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Book Synopsis The Stroke Book by : Michel T. Torbey
Download or read book The Stroke Book written by Michel T. Torbey and published by Cambridge University Press. This book was released on 2013-07-18 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential companion for busy professionals seeking to navigate stroke-related clinical situations successfully and make quick informed treatment decisions.
Book Synopsis Molecular Biomarkers in the Prediction, Diagnosis, and Prognosis of Neurodegenerative Diseases by : Yuzhen Xu
Download or read book Molecular Biomarkers in the Prediction, Diagnosis, and Prognosis of Neurodegenerative Diseases written by Yuzhen Xu and published by Frontiers Media SA. This book was released on 2023-07-06 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Imaging Acute Neurologic Disease by : Massimo Filippi
Download or read book Imaging Acute Neurologic Disease written by Massimo Filippi and published by Cambridge University Press. This book was released on 2014-09-11 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of best practice in using diagnostic imaging in acute neurologic conditions. The symptom-based approach guides the choice of the available imaging tools for efficient, accurate, and cost-effective diagnosis. Effective examination algorithms integrate neurological and imaging concepts with the practical demands and constraints of emergency care.
Book Synopsis Immunological Mechanisms and Therapies in Brain Injuries and Stroke by : Jun Chen
Download or read book Immunological Mechanisms and Therapies in Brain Injuries and Stroke written by Jun Chen and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent research has revealed the importance of immunological mechanisms and inflammation in delaying damage and/or promoting repair after an acute injury to the central nervous system. This book provides a comprehensive and up-to-date overview of the role of immunological mechanisms and therapies for treating acute neurological injuries such as cerebral ischemia, hemorrhage, and brain and spinal cord trauma. In several sections, the contributing authors provide a review of immunological mechanisms involved in neurological injury and of various translational and clinical research aimed at harnessing those mechanisms for better patient outcomes.
Author :Stavros V. Konstantinides Publisher :Springer Science & Business Media ISBN 13 :1597452874 Total Pages :273 pages Book Rating :4.5/5 (974 download)
Book Synopsis Management of Acute Pulmonary Embolism by : Stavros V. Konstantinides
Download or read book Management of Acute Pulmonary Embolism written by Stavros V. Konstantinides and published by Springer Science & Business Media. This book was released on 2007-12-31 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical volume highlights traditional, novel, and evolving aspects of the diagnosis and treatment of pulmonary embolism (PE). The contributors comprise an international team of experts. Important aspects of diagnosis, risk stratification, and differential treatment of patients with PE are presented in a concise, yet comprehensive manner. Emphasis is placed on specific issues related to PE, including pregnancy, cancer, thrombophilia, and air travel.
Book Synopsis Hemocoagulative Problems in the Critically Ill Patient by : Giorgio Berlot
Download or read book Hemocoagulative Problems in the Critically Ill Patient written by Giorgio Berlot and published by Springer Science & Business Media. This book was released on 2012-04-05 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the very beginning of critical care medicine, much attention has been paid to the risk of bleeding, but only recently the risk of thrombosis has been recognized in critical patients; in fact, current laboratory investigations aimed to monitor blood coagulation are more focused on the assessment of the hemorrhagic than of the thrombotic risk. Since mid-90s, many studies have detected powerful pro-thrombotic actions of endogenous mediators in sepsis and other inflammatory conditions, including trauma and postoperative status. Unfortunately, the related complication are both hard to detect and extremely harmful. The volume provides a full coverage of the hemocoagulative problems in anesthesia and intensive care, taking into consideration the physiology and monitoring of hemostasis, its relation with sepsis, and the specific aspects of the various critical conditions - from trauma to burns, to heart and transplant surgery or acute renal failure.
Book Synopsis Recent Advances in Neurotraumatology by : Norio Nakamura
Download or read book Recent Advances in Neurotraumatology written by Norio Nakamura and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: The dawn of neurosurgery can be traced back to the first description preserved in the Edwin Smith papyrus' (3000 Be) which dealt with head and spinal injury. In the course of 5000 years, since the first record in Egypt, advances in lifestyle and technology have brought about our modern civilized society. However, as a result of civilization, currently the total number of severe head injuries worldwide is believed to exceed 10000000 and the number of severe spinal injuries is believed to be more than 75 000 each year. This means that central nervous system injury is not only the oldest topic in neurosurgery, but that it is also of critical importance in modern life. Taking these problems into consideration, the International Neurotraumatology Committee was organized in 1965 as an affiliated Committee of the World Federation of Neurosurgical Societies. The first scientific meeting was convened by the Committee in Marseilles in 1970. Nine further meetings were subsequently held, in Europe, Africa, and South America. The meeting was first named "International Conference on Recent Advances in Neurotrauma tology" (ICRAN) by Professor Phillip Harris, when the scientific meeting was held in Edinburgh in 1982. The tenth meeting, (ICRAN 1992), the first one in Asia, was held at Karuizawa, Japan, from September 23rd to 26th, 1992.
Book Synopsis Precision Medicine in Stroke by : Ana Catarina Fonseca
Download or read book Precision Medicine in Stroke written by Ana Catarina Fonseca and published by Springer. This book was released on 2022-05-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive coverage of the state of the art in precision medicine in stroke. It starts by explaining and giving general information about precision medicine. Current applications in different strokes types (ischemic, haemorrhagic) are presented from diagnosis to treatment. In addition, ongoing research in the field (early stroke diagnosis and estimation of prognosis) is extensively discussed. The final part provides an in-depth discussion of how different interdisciplinary areas like artificial intelligence, molecular biology and genetics are contributing to this area. Precision Medicine in Stroke provides a practical approach to each chapter, reinforcing clinical applications and presenting clinical cases. This book is intended for all clinicians that interact with stroke patients (neurologists, internal medicine doctors, general practitioners, neurosurgeons), students and basic researchers.
