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Handbook Of Chiral Chemicals Second Edition
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Book Synopsis Handbook Of Chiral Chemicals by : David John Ager
Download or read book Handbook Of Chiral Chemicals written by David John Ager and published by CRC Press. This book was released on 1999-01-04 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes the problems associated with large, commercial-scale syntheses of chiral molecules and the relatively small number of reactions that can be used to achieve these syntheses. The book discusses commercially viable and still-developing methods of compound manufacture, and reviews the best-selling chiral compounds as of 1996.
Book Synopsis Handbook of Chiral Chemicals by : David Ager
Download or read book Handbook of Chiral Chemicals written by David Ager and published by CRC Press. This book was released on 2005-10-21 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. "The Handbook of Chiral Chemicals, Second Edition" highlights the problems associated with the production of chiral compounds on a commercial scale. The handbook fir
Book Synopsis Handbook of Inorganic Compounds, Second Edition by : Dale L. Perry
Download or read book Handbook of Inorganic Compounds, Second Edition written by Dale L. Perry and published by CRC Press. This book was released on 2011-05-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated edition of the Handbook of Inorganic Compounds is the perfect reference for anyone that needs property data for compounds, CASRN numbers for computer or other searches, a consistent tabulation of molecular weights to synthesize inorganic materials on a laboratory scale, or data related to physical and chemical properties. Fully revised, the second edition includes new data on inorganic optical materials, radiation detection inorganics, thermochromic compounds, piezochromic compounds, catalysts, superconductors, and luminescent (fluorescent and phosphorescent) inorganics. Compiled for chemists, chemical engineers, materials scientists, and other scientists, this handbook provides: Basic, essential property data for compounds that they wish to use in their database compilations, research, and applications work American Chemical Society (ACS) Chemical Abstract Registry Numbers (RNs, or CAS numbers) for computer and other searches. An effort has been made to include CAS numbers for both hydrated chemical compounds and their parent anhydrous compounds A tabulation of molecular weights for calculations. In this handbook, molecular weights have been calculated to three decimal places in all cases Textbook and inorganic chemistry resource books The Handbook of Inorganic Compounds: Second Edition consists of data for 3,326 selected gas, liquid, and solid compounds, including representative compounds of several different classes of compounds. Choices of compounds were based on criteria such as inclusion of the compounds in various handbooks of laboratory chemicals, discussion in recent research publications, compounds important to inorganic materials chemistry, and comments of the Advisory Committee guiding the production of the first edition of the handbook.
Book Synopsis Chiral Analysis by : P.L. Polavarapu
Download or read book Chiral Analysis written by P.L. Polavarapu and published by Elsevier. This book was released on 2018-05-30 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chiral Analysis: Advances in Spectroscopy, Chromatography and Emerging Methods, Second Edition covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals, including chemistry graduate students, analytical chemists, organic chemists, professionals in the pharmaceutical industry, and others with an interest in chirality and chiral analysis. This thoroughly revised second edition covers several new, important areas of chiral analysis that have emerged since the first edition. Three of the new methods provide higher sensitivity than can be realized with the current methods and are expected to become mainstream applications: cavity based methods offer vastly higher sensitivity than conventional polarimetric methods, microwave chiral detection provides unsurpassed sensitivity for identifying diastereomers, and the rotating electric field method offers a competing new approach for the separation of enantiomers. Another topic, chirality in extraterrestrial life, has not been discussed in any other book and is important for understanding the origin of life. Offers the only book to cover both spectroscopic and separation methods in a single volume Provides an up-to-date and detailed review of the various techniques available, including new techniques that have emerged since the first edition Includes contributions from a range of leading experts in the field, now edited by award-winning chirality researcher Prasad Polavarapu
Book Synopsis Handbook for Chemical Process Research and Development by : Wenyi Zhao (Chemist)
Download or read book Handbook for Chemical Process Research and Development written by Wenyi Zhao (Chemist) and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This fully updated second edition reflects the significant changes in process chemistry since the first edition and includes more common process issues such as safety, cost, robustness, and environmental impact. Some areas have made notable progress such as process safety, stereochemistry, new reagents and reagent surrogates. Forty years ago there were few process research and development activities in the pharmaceutical industry, partly due to the simplicity of drug molecules. With increasing structural complexity especially the introduction of chiral centers into drug molecules and stricter regulations, process R&D has become one of the critical departments for pharmaceutical companies"--
Book Synopsis Handbook of Metathesis, Volume 2 by : Robert H. Grubbs
Download or read book Handbook of Metathesis, Volume 2 written by Robert H. Grubbs and published by John Wiley & Sons. This book was released on 2015-02-18 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of the "go-to" reference in this field is completely updated and features more than 80% new content, with emphasis on new developments in the field, especially in industrial applications. No other book covers the topic in such a comprehensive manner and in such high quality. Edited by the Nobel laureate R. H. Grubbs and D. J. O´Leary, Volume 2 of the 3-volume work focusses on applications in organic synthesis. With a list of contributors that reads like a "Who's-Who" of metathesis, this is an indispensable one-stop reference for chemists in academia and industry. View the set here - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527334246.html Other available volumes: Volume 1: Catalyst Development and Mechanism, Editors: R. H. Grubbs and A. G. Wenzel - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339485.html Volume 3: Polymer Synthesis, Editors: R. H. Grubbs and E. Khosravi - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339507.html
Book Synopsis Handbook for Chemical Process Research and Development, Second Edition by : Wenyi Zhao
Download or read book Handbook for Chemical Process Research and Development, Second Edition written by Wenyi Zhao and published by CRC Press. This book was released on 2023-03-21 with total page 938 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated second edition reflects the significant changes in process chemistry since the first edition and includes more common process issues such as safety, cost, robustness, and environmental impact. Some areas have made notable progress such as process safety, stereochemistry, new reagents and reagent surrogates. Forty years ago there were few process research and development activities in the pharmaceutical industry, partly due to the simplicity of drug molecules. With increasing structural complexity especially the introduction of chiral centers into drug molecules and stricter regulations, process R&D has become one of the critical departments for pharmaceutical companies. Features: This unique volume now in its second edition is designed to provide readers with an unprecedented strategy and approach which will help chemists and graduate students develop chemical processes in an efficient manner. Promotes an industrial mindset concerning safety and commercial viability when developing methods. The author discusses development strategies with case studies and experimental procedures. Focuses on mechanism-guided process development which provides readers with practical strategies and approaches. Addresses more common process issues such as safety, cost, robustness, and environmental impact. This book provides a new direction for scientists, researchers, and students in materials science and polymer chemistry who seek to better understand the chemistry behind conducting polymers and improve their performance for use in advanced energy applications.
Book Synopsis Enantioselective Chemical Synthesis by : Elias J. Corey
Download or read book Enantioselective Chemical Synthesis written by Elias J. Corey and published by Elsevier. This book was released on 2013-10-23 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by world-renowned and best-selling experts, Nobel Laureate E. J. Corey and Laszlo Kurti, Enantioselective Chemical Synthesis offers an authoritative and comprehensive overview of the field’s progress; the processes and tools for key formations; future development for complex, stereocontrolled (enantiomeric or diastereoisomeric) molecules; and valuable examples of multi-step syntheses. Utilizing a color-coded scheme to illustrate chemical transformations, Enantioselective Chemical Synthesis provides clear explanation and guidance through vital asymmetrical syntheses and insight into the next steps for the field. Researchers, professionals, and academics will benefit from this valuable, thorough, and unique resource. In Part I, the authors present clearly, comprehensively and concisely the most useful enantioselective processes available to synthetic chemists. Part II provides an extensive discussion of the most logical ways to apply these new enantioselective methods to the planning of syntheses of stereochemically complex molecules. This hitherto neglected area is essential for the advancement of enantioselective synthesis to a more rational and powerful level. Part III describes in detail many reaction sequences which have been used successfully for the construction of a wide variety of complex target molecules Clearly explains stereochemical synthesis in theory and practice Provides a handy tool box for scientists wishing to understand and apply chiral chemical synthesis Describes almost 50 real life examples of asymmetric synthesis in practice and examines how the chiral centers were introduced at key synthetic stages
Book Synopsis Handbook of Reagents for Organic Synthesis: Chiral reagents for asymmetric synthesis by : Leo A. Paquette
Download or read book Handbook of Reagents for Organic Synthesis: Chiral reagents for asymmetric synthesis written by Leo A. Paquette and published by . This book was released on 2003 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Asymmetric Catalysis on Industrial Scale by : Hans Ulrich Blaser
Download or read book Asymmetric Catalysis on Industrial Scale written by Hans Ulrich Blaser and published by John Wiley & Sons. This book was released on 2011-08-04 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of the pioneering work on this hot topic captures the major trends and latest achievements in the art of asymmetric catalysis on an industrial scale. A number of completely new real-life case studies written by the world leaders in their respective areas provide a compact and qualified insight into this developing field. The resulting ready reference and handbook collates first-hand and valuable information within a context where it can be easily found. The high-quality contributions illustrate the relevant environments and situations, such as time pressure, how the catalytic step fits into the overall synthesis, or competition with other synthetic approaches, as well as the typical problems encountered in the various phases, including finding/developing the catalyst and optimization of the process or choice of equipment. Both successful and unsuccessful approaches to solve these problems are described.
Book Synopsis Differentiation of Chiral Compounds Using NMR Spectroscopy by : Thomas J. Wenzel
Download or read book Differentiation of Chiral Compounds Using NMR Spectroscopy written by Thomas J. Wenzel and published by John Wiley & Sons. This book was released on 2018-06-01 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: An updated guide to the most current information available for determining how to use NMR spectroscopy to differentiate chiral compounds Differentiation of Chiral Compounds Using NMR Spectroscopy offers a thoroughly revised second edition to the essential volume that puts the focus on the chiral systems that are commercially available and have been widely vetted for use in NMR spectroscopy. The text covers a broad range of reagents that make it possible to determine the enantiomeric purity and assign the absolute configuration of many classes of compounds. Comprehensive in scope, the text describes the chiral NMR differentiating agents as derivatizing agents, solvating agents, metal-based reagents and liquid crystals and gels, and explains the range and types of compounds for which they can be used for analysis. New to this edition are the most recent findings in the field as well as the development of advanced NMR measurement techniques that allow for the simplification of complex spectra resulting in more readily identified enantiodifferentiation. This important resource: Includes the most recent coverage of a large range of compounds that can be analyzed using chiral NMR reagents Explores the use of chiral NMR reagents and explains their relationship to the stereochemistry of the analyzed molecules Offers the essential information needed to help decide which method is the best NMR method to apply to a class or molecules Contains experimental strategies for using the reagents that are likely to improve the quality of the results Differentiation of Chiral Compounds Using NMR Spectroscopy is a comprehensive guide designed for investigators planning to use NMR spectroscopy to determine enantiomeric purity or assign the absolute configuration of a compound.
Book Synopsis Handbook of Metathesis, 3 Volume Set by : Robert H. Grubbs
Download or read book Handbook of Metathesis, 3 Volume Set written by Robert H. Grubbs and published by John Wiley & Sons. This book was released on 2015-05-26 with total page 1639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the complete breadth of the olefin metathesis reaction. The second edition of the ultimate reference in this field is completely updated and features more than 80% new content, with the focus on new developments in the field, especially in industrial applications. No other book covers the topic in such a comprehensive manner and in such high quality, and this new edition retains the three-volume format: Catalyst Development, Applications in Organic Synthesis and Polymer Synthesis. Edited by a Nobel laureate in the field, and with a list of contributors that reads like a "Who's-Who" of metathesis, this is an indispensable one-stop reference for organic, polymer and industrial chemists, as well as chemists working with organometallics. Individual volumes also available separately to purchase Volume 1: Catalyst Development - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339485.html Volume 2: Applications in Organic Synthesis - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339493.html Volume 3: Polymer Synthesis - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339507.html
Book Synopsis Chiral Intermediates by : Cynthia A. Challener
Download or read book Chiral Intermediates written by Cynthia A. Challener and published by John Wiley & Sons. This book was released on 2001-09 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the early twentieth century the relevance of chirality to the pharmaceutical industry was established by the fact that one enantiomer of hyoscyamine possessed greater pharmacological activity than the other. Today, most new drugs and those under development consist of a single optically active isomer, and chirality is also becoming an issue for the agrochemical and other industries. Regulatory agencies throughout the world are currently reviewing the importance of chirality with regard to pharmaceutical and agrochemical products. New guidelines from such agencies have been key drivers for the focus on single enantiomer products in these industries. These scientific and regulatory developments have created the need for a guide for workers in the pharmaceutical and chemical industries seeking information on chiral molecules, processes, and commercially available chiral chemicals. Chiral Intermediates presents the chemical professional with a comprehensive listing of over 4700 available chiral chemicals including specific data of interest for each entry in the listing. Its companion volume, Chiral Drugs presents the same detailed information for over 2000 chiral drugs. The 'Chiral Pool' of readily available, relatively inexpensive chiral compounds has been expanding at a rapid rate as more and more products are produced in large quantities at economical prices. New developments in various technologies for isolating, preparing, and purifying chiral materials have greatly increased the opportunities for utilizing optically pure compounds in commercial applications. Novel techniques for classical resolution, new methodologies for developing selective enzymes for biocatalysis, advances in the application of microorganisms for chemical production, and continued progress in the area of asymmetric synthesis have all contributed to the growth of this field. Part I contains four chapters which provide an introduction to topics relevant to the field of chiral chemistry and includes a brief overview of chirality, a short discussion on the current market drivers in the area of chiral chemistry, and a basic presentation of the various sources and methods for obtaining chiral compounds. Part II presents entries for 4700 commercially available chiral compounds. For each main entry, the chemical name and a list of trade names and synonyms is provided; the CAS Registry Number, the European Inventory of Existing Commercial Chemical Substances (EINECS) number, and the Merck Index (12th edition) number are given when available. The physical properties, including specific rotation, of each compound are described and indicated applications are presented. The structure of nearly every compound is provided, and the manufacturers and suppliers of the compounds are also given. Indexes, including a master index of names and synonyms and an index of custom manufacturing services for production of chiral compounds, are appended. Chiral Intermediates provides an introduction to the types of sources and methods currently in use for obtaining chiral molecules and is an invaluable resource for information on available chiral molecules. Chiral Intermediates and Chiral Drugs are the most comprehensive and detailed guides to chiral compounds available.
Book Synopsis CRC Handbook of Organic Photochemistry and Photobiology, Volumes 1 & 2 by : William M. Horspool
Download or read book CRC Handbook of Organic Photochemistry and Photobiology, Volumes 1 & 2 written by William M. Horspool and published by CRC Press. This book was released on 2003-09-29 with total page 2898 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this best-selling handbook is bigger, more comprehensive, and now completely current. In addition to thorough updates to the discussions featured in the first edition, this edition includes 66 new chapters that reflect recent developments, new applications, and emerging areas of interest. Within the handbook's 145 critically r
Book Synopsis Handbook of Preformulation by : Sarfaraz K. Niazi
Download or read book Handbook of Preformulation written by Sarfaraz K. Niazi and published by CRC Press. This book was released on 2019-03-22 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preformulation studies are the physical, chemical, and biological studies needed to characterize a drug substance for enabling the proper design of a drug product, whereas the effectiveness of a drug product is determined during the formulation studies phase. Though the two disciplines overlap in practice, each is a significantly distinct phase of new drug development. Entirely focused on preformulation principles, this fully revised and updated Handbook of Preformulation: Chemical, Biological, and Botanical Drugs, Second Edition provides detailed descriptions of preformulation methodologies, gives a state-of-the-art description of each technique, and lists the currently available tools useful in providing a comprehensive characterization of a new drug entity. Features: Addresses the preformulation studies of three different types of new active entities - chemical, biological, and botanical, which is the latest established class of active ingredient classified by the FDA Illustrates the activities comprised in preformulation studies and establishes a method of tasking for drug development projects Includes extensive flow charts for characterization decision making Gives extensive theoretical treatment of principles important for testing dissolution, solubility, stability, and solid state characterization Includes over 50% new material
Book Synopsis Practical Process Research and Development by : Neal G. Anderson
Download or read book Practical Process Research and Development written by Neal G. Anderson and published by Academic Press. This book was released on 2012-05-23 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries, this book describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. It describes hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." Second Edition highlights:• Reflects the current thinking in chemical process R&D for small molecules• Retains similar structure and orientation to the first edition. • Contains approx. 85% new material• Primarily new examples (work-up and prospective considerations for pilot plant and manufacturing scale-up)• Some new/expanded topics (e.g. green chemistry, genotoxins, enzymatic processes)• Replaces the first edition, although the first edition contains useful older examples that readers may refer to Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more Presents guidelines for implementing and troubleshooting processes
Download or read book Carotenoids written by George Britton and published by Birkhäuser. This book was released on 2012-12-06 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the number of natural carotenoid structures reported rising above 700, there is a clear need for a single reference work containing data on all these compounds. This Handbook includes all natural carotenoids and common isolation artefacts for which structures have been assigned up to the end of 2001. For each compound, it provides selected key references and critically assessed information about natural occurrence and isolation, and spectroscopic data for identification. A standard full-page entry is given for each compound that has been characterised unambiguously, showing - Common name - IUPAC name - Structure, including stereochemistry, when assigned - Spectroscopic data: UV/Vis (with illustration); MS; CD; NMR (type and references) - Chemical synthesis (references) - Natural sources and outline of isolation procedure - Remarks, e.g. further spectroscopic data, stability, properties, derivatives - Selected key references
