Guided Regeneration of the Human Skin

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Author :
Publisher : Linköping University Electronic Press
ISBN 13 : 9175191148
Total Pages : 98 pages
Book Rating : 4.1/5 (751 download)

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Book Synopsis Guided Regeneration of the Human Skin by : Erika Nyman

Download or read book Guided Regeneration of the Human Skin written by Erika Nyman and published by Linköping University Electronic Press. This book was released on 2015-03-17 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every day and in all parts of the world, humans experience different grades of wounding and tissue loss of the skin, thus initiating one of the most complex biological processes. Acute and chronic wounds, as well as the additional problem of skin scarring, involve not only great suffering for the patient but also extensive health care costs for the society. Although the wound-healing process is a wellstudied field much knowledge must be gained to unlock the door to regenerative pathways in humans. Epidermis heals by complete regeneration, but dermal and full thickness injuries heal with fibrosis and scar formation. In Papers I and II, we studied whether dermal scarring could be turned into regeneration by using two different types of threedimensional dermal scaffolds. In Paper I, we studied a solid scaffold made of poly(urethane urea), initially in vitro then followed by in vivo studies. In Paper II, we intradermally injected a liquid three-dimensional scaffold consisting of porous gelatin spheres in human healthy volunteers. Both materials showed ingrowth of functional fibroblasts and blood vessels and appeared to stimulate regeneration while slowly degrading. This finding could be of significant clinical importance, for example in burn wound care or after cancer surgery. In Papers III and IV, we wanted to study the effects of amniotic fluid and hyaluronic acid on adult wound healing, because early fetal wounds re-epithelialize rapidly and naturally heal dermis by regeneration without the need of a dermal scaffold. Amniotic fluid, naturally rich in hyaluronic acid, induced an accelerated reepithelialization of adult human wounds in vitro, and hyaluronic acid seemed to be important for this effect. Stimulation with exogenous hyaluronic acid in vivo induced accelerated re-epithelialization and an altered protein expression in healthy human volunteers. The inflammatory phase of wound healing, as measured by tissue viability imaging, was not affected by hyaluronic acid. Elucidating the effects of amniotic fluid and hyaluronic acid on the wound-healing process may allow improved treatment of wounds with impaired healing. Studies on finding new dermal scaffolds and studies on the positive effect of amniotic fluid or hyaluronic acid on the wound-healing process are two different ways of gaining insight that may lead to regeneration and improved wound healing for the patient.

Skin Tissue Engineering and Regenerative Medicine

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Author :
Publisher : Academic Press
ISBN 13 : 012801797X
Total Pages : 468 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Skin Tissue Engineering and Regenerative Medicine by : Mohammad Albanna

Download or read book Skin Tissue Engineering and Regenerative Medicine written by Mohammad Albanna and published by Academic Press. This book was released on 2016-01-14 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients. Skin Tissue Engineering and Regenerative Medicine provides a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches which expanded available therapies for patients and additional research collaboration. This work expands on the primary literature on the state of the art of cell therapies and biomaterials to review the most widely used surgical therapies for the specific clinical scenarios. - Explores cellular and molecular processes of wound healing, scar formation, and dermal repair - Includes examples of animal models for wound healing and translation to the clinical world - Presents the current state of, and clinical opportunities for, extracellular matrices, natural biomaterials, synthetic biomaterials, biologic skin substitutes, and adult and fetal stem and skin cells for skin regenerative therapies and wound management - Discusses new innovative approaches for wound healing including skin bioprinting and directed cellular therapies

Evidence-Based Dermatology

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Publisher : John Wiley & Sons
ISBN 13 : 9781444300178
Total Pages : 740 pages
Book Rating : 4.3/5 (1 download)

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Book Synopsis Evidence-Based Dermatology by : Hywel Williams

Download or read book Evidence-Based Dermatology written by Hywel Williams and published by John Wiley & Sons. This book was released on 2009-01-22 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evidence-based Dermatology, Second Edition is aunique book in the field of clinical dermatology. Written andedited by some of the world’s leading experts inevidence-based dermatology, it takes a highly evidence-basedapproach to the treatment of all major and many of the less commonskin conditions. The toolbox at the beginning of the book explaining how tocritically appraise different studies, along with the comprehensivereviewing and appraisal of evidence in the clinical chapters makesthis book distinctive in its field as do the treatmentrecommendations which are based on the discussion of the bestavailable evidence using a question-driven approach and a commonstructure on dealing with efficacy, drawbacks and implications forclinical practice.

Mechanisms of Vascular Disease

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Publisher : University of Adelaide Press
ISBN 13 : 1922064009
Total Pages : 589 pages
Book Rating : 4.9/5 (22 download)

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Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Skin Tissue Engineering

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Publisher : Springer Nature
ISBN 13 : 1493994735
Total Pages : 260 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Skin Tissue Engineering by : Sophie Böttcher-Haberzeth

Download or read book Skin Tissue Engineering written by Sophie Böttcher-Haberzeth and published by Springer Nature. This book was released on 2019-05-30 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides protocols describing the isolation and culture of diverse cell types stemming from the skin and the use of these cells and cell constructs for wound healing, bioengineering applications, and translational medicine purposes. The book is divided into three sections describing the isolation and culture of diverse skin cells, managing these cells within co-culture systems and skin models, as well as using these skin models in a test setting. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Skin Tissue Engineering: Methods and Protocols serves as a vital aid to basic and clinical researchers such as biologists, physicians, and biomedical engineers working with and being interested in basic science, and clinically and laboratory-applicable translational regenerative medicine.

Tissue Regeneration

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Publisher : BoD – Books on Demand
ISBN 13 : 1789232600
Total Pages : 207 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Tissue Regeneration by : Hussein Abdelhay Essayed Kaoud

Download or read book Tissue Regeneration written by Hussein Abdelhay Essayed Kaoud and published by BoD – Books on Demand. This book was released on 2018-06-06 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue regeneration is a vast subject, with many different important aspects to consider. Regenerative medicine is a new branch of medicine that tries to change the course of chronic diseases and, in many cases, regenerates the organ systems that fail due to age, disease, damage, or genetic defects. The main purpose of this book is to point out the interest of some important topics of tissue regeneration and the progress in this field as well as the variety of different surgical fields and operations. This book includes 7 sections and 11 chapters that provide an overview of the essentials in tissue regeneration science and their potential applications in surgery. The authors of each chapter have given consolidated information on ground realities and attempted to provide a comprehensive knowledge of tissue engineering and regeneration. This book will be useful to researchers and students of biological and biomedical sciences (medical and veterinarian researchers).

Periodontal Regeneration

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Author :
Publisher : Quintessence Publishing (IL)
ISBN 13 :
Total Pages : 230 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Periodontal Regeneration by : Alan M. Polson

Download or read book Periodontal Regeneration written by Alan M. Polson and published by Quintessence Publishing (IL). This book was released on 1994 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: They assert that regeneration can be achieved only by proper understanding of all cellular, tissue, and clinical components, and they provide the foundation necessary for this understanding.

Human Amniotic Membrane: Basic Science And Clinical Application

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Publisher : World Scientific
ISBN 13 : 9813226366
Total Pages : 380 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Human Amniotic Membrane: Basic Science And Clinical Application by : Nazly Hilmy

Download or read book Human Amniotic Membrane: Basic Science And Clinical Application written by Nazly Hilmy and published by World Scientific. This book was released on 2017-08-23 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive guide for all tissue bank operators to screen, procure and process amniotic membrane for clinical application.The amnion comes close to being the ideal biological membrane or dressing — readily available, inexpensive to procure and process. Its basic science is discussed in detail — anatomy, biological and biomechanical properties.It can be procured from the placenta in normal vaginal deliveries and from Caesarean Sections. Processing is by freeze-drying or by air-drying process with sterilisation using gamma irradiation.The product has low antigenicity, has anti-microbial properties with ability to enhance epithelisation with marked relief of pain. It is useful as a dressing for wounds — flap wounds, burn wounds, injury wounds, diabetic ulcers, leprous ulcers and post-surgery wounds and post-radiation wounds. It is also used as a biological scaffold for cells in tissue engineering. Its ophthalmic applications include treatment of corneal ulcers and conjunctival tumours. Oral uses include gingiva depigmentation and periodontal regeneration.

Principles of Regenerative Medicine

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Publisher : Academic Press
ISBN 13 : 0123814235
Total Pages : 1203 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Principles of Regenerative Medicine by : Anthony Atala

Download or read book Principles of Regenerative Medicine written by Anthony Atala and published by Academic Press. This book was released on 2010-12-16 with total page 1203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. - Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology - The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine - New discoveries from leading researchers on restoration of diseased tissues and organs

Biomaterials for Skin Wound Repair: Tissue Engineering, Guided Regeneration, and Wound Scarring Prevention

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889713296
Total Pages : 143 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Biomaterials for Skin Wound Repair: Tissue Engineering, Guided Regeneration, and Wound Scarring Prevention by : Ubaldo Armato

Download or read book Biomaterials for Skin Wound Repair: Tissue Engineering, Guided Regeneration, and Wound Scarring Prevention written by Ubaldo Armato and published by Frontiers Media SA. This book was released on 2021-09-15 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Giuliano Freddi is Chief Scientific Officer and co-founder of the company Silk Biomaterials srl. All other Guest Editors declare no competing interests with regards to the Topic subject.

Acute & Chronic Wounds

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323069436
Total Pages : 671 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Acute & Chronic Wounds by : Ruth A. Bryant

Download or read book Acute & Chronic Wounds written by Ruth A. Bryant and published by Elsevier Health Sciences. This book was released on 2012-01-01 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rev. ed. of: Acute and chronic wounds / [edited by] Ruth A. Bryant, Denise P. Nix. 3rd ed. c2007.

Applications of human skin in vitro

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Publisher : Linköping University Electronic Press
ISBN 13 : 9176858952
Total Pages : 113 pages
Book Rating : 4.1/5 (768 download)

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Book Synopsis Applications of human skin in vitro by : Susanna Lönnqvist

Download or read book Applications of human skin in vitro written by Susanna Lönnqvist and published by Linköping University Electronic Press. This book was released on 2015-12-10 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic wounds are a substantial problem in today’s health care and place significant strains on the patient. Successful modelling of the wound healing process is pivotal for the advancement of wound treatment research. Wound healing is a dynamic and multifactorial process involving all constituents of the skin. The progression from haemostasis and inflammation to proliferation of epidermal keratinocytes and dermal fibroblasts, and final scar maturation can be halted and result in a chronic wound that fails to re-epithelialise. The wound healing process constitutes an example of dynamic reciprocity in tissue where cellular changes take place on cues from the extracellular matrix and vice versa when tissue homeostasis is disturbed. The extracellular matrix provides a structural context for the resident cells and the epidermal keratinocytes, and a functioning interplay between the two tissue compartments is crucial for successful wound healing to take place. Work included in this thesis has applied viable human full thickness skin in vitro to investigate the re-epithelialisation process and barrier function of intact skin.The use of full thickness skin in vitro can take into account the contextual aspect of the process where the epidermal keratinocytes are activated and obtain a migratory phenotype, and are continuously dependent on the cues from the extracellular matrix and support of the dermis. When utilising skin for studies on re-epithelialisation, circular standardised full thickness wounds were created and cultured for up to four weeks in tissue culture. In paper I, the organisation of a thick neoepidermis was investigated in the in vitro wound healing model when resident cells were provided with a porous suspended three dimensional gelatin scaffold. In paper II we investigated the use of a fluorescent staining conventionally used for proliferation studies to facilitate the tracing of transplanted epidermal cells in in vitro wounds, in order to improve and expand the use of the model. In paper III the model was utilised to investigate the treatment approach of acidification of wounds to evaluate the suitability of such intervention in regards to keratinocyte function and re-epithelialisation. Studies on re-epithelialisation with the aid of the in vitro wound healing model provided insight in neoepidermal structure with porous gelatin scaffolding in the wound, a novel methodological approach to tracing cells and response to constrained wound healing environment. In paper IV, intact human skin was evaluated for modelling the cytotoxic response after exposure to a known irritant compound. To study barrier function, intact skin was exposed to irritants by restricting exposure topically, and full thickness skin in vitro was found suitable for modelling cytotoxicity responses. Employing human full thickness skin in vitro makes use of the actual target tissue of interest with epidermal and dermal cells, and full barrier function.

Product Guide to Skin & Wound Care

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496388100
Total Pages : 627 pages
Book Rating : 4.4/5 (963 download)

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Book Synopsis Product Guide to Skin & Wound Care by : Cathy Hess

Download or read book Product Guide to Skin & Wound Care written by Cathy Hess and published by Lippincott Williams & Wilkins. This book was released on 2019-11-04 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Choose the best possible skin and wound care products to support your patients’ skin health and wound healing, with the invaluable Product Guide to Skin and Wound Care, 8th Edition. Listing 294 products in alphabetical order, this handy product guide for wound care practitioners across all practice settings offers detailed information—sizes, action, indications, contraindications, application, and removal information—so that your choices stay informed and accurate.

Principles of Regenerative Biology

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Publisher : Elsevier
ISBN 13 : 0080477968
Total Pages : 400 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Principles of Regenerative Biology by : Bruce M. Carlson

Download or read book Principles of Regenerative Biology written by Bruce M. Carlson and published by Elsevier. This book was released on 2011-10-10 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the explosion of knowledge from molecular biology and the burgeoning interest in generating or regenerating tissues or organs through various bioengineering or stem cell approaches, many scientists and students have shown a renewed interest in the phenomenon of regeneration. Because relatively few have had the luxury of being able to approach the phenomenon of regeneration from a broad biological perspective, Dr. Carlson has produced a book that outlines the fundamental principles of regeneration biology. Subject matters focus principally on regeneration in vertebrate systems, but also invertebrate regeneration. In order to manipulate regenerative processes, it is important to understand the underlying principles of regeneration. Principles of Regnerative Biology is the key introductory reference for all developmental biologists, geneticists, and tissue and stem cell researchers. - Creates a general understanding of one of the most fascinating and complex phenomena in biology - Discusses the ability and diversity of regeneration in various organisms - Explains the history and origins of cells in regenerating systems - Includes information on stem cells and its important role in regeneration

Anatomy and Physiology

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Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.1/5 (728 download)

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Book Synopsis Anatomy and Physiology by : J. Gordon Betts

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Epidermis in Wound Healing

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Publisher : CRC Press
ISBN 13 : 0203495322
Total Pages : 404 pages
Book Rating : 4.2/5 (34 download)

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Book Synopsis The Epidermis in Wound Healing by : David T. Rovee

Download or read book The Epidermis in Wound Healing written by David T. Rovee and published by CRC Press. This book was released on 2003-12-29 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: New biological techniques and a revival of interest in both acute and chronic wound healing have led to an enormously improved understanding of the cellular and chemical complexities of the healing process. Exciting developments in the evolution of epidermal biology are creating new opportunities for research and clinical applications in wound heal

Shine Bright Like a Diamond: The Ultimate Guide to Glowing Skin

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Author :
Publisher : KOKOSHUNGSAN®
ISBN 13 :
Total Pages : 62 pages
Book Rating : 4./5 ( download)

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Book Synopsis Shine Bright Like a Diamond: The Ultimate Guide to Glowing Skin by : Shu Chen Hou

Download or read book Shine Bright Like a Diamond: The Ultimate Guide to Glowing Skin written by Shu Chen Hou and published by KOKOSHUNGSAN®. This book was released on with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: Are you tired of dull, lackluster skin that just won't glow no matter what you do? Look no further than "Shine Bright Like a Diamond: The Ultimate Guide to Glowing Skin" – your one-stop-shop for all things radiant beauty. This comprehensive guide covers everything from the basics of skin care to advanced techniques for achieving a flawless complexion. You'll learn about the different types of skin and how to care for each one, as well as the best foods and supplements for promoting healthy, glowing skin. But this guide isn't just about what to put on your skin – it's also about what to put in your body. You'll discover the importance of hydration, sleep, and stress management in achieving radiant skin, and learn about the best exercises and activities for promoting healthy blood flow and a youthful complexion. And if you're looking for specific tips and tricks, we've got you covered there too. Our DIY Skincare section will teach you how to create your own natural remedies for glowing skin, and our Advanced Skincare Techniques chapter will take your routine to the next level with cutting-edge methods for achieving a flawless complexion. Don't settle for lackluster skin – it's time to shine bright like a diamond. Order "Shine Bright Like a Diamond: The Ultimate Guide to Glowing Skin" today and unlock the secrets to radiant beauty.