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Guidance Document On Measurement Uncertainty For Gmo Testing Laboratories
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Book Synopsis Testing and Analysis of GMO-containing Foods and Feed by : Salah E. O. Mahgoub
Download or read book Testing and Analysis of GMO-containing Foods and Feed written by Salah E. O. Mahgoub and published by CRC Press. This book was released on 2019-01-15 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: An increasing number of genetically modified organisms (GMOs) continues to be produced every day. In response to the concerns raised by the development of GMOs and their incorporation in foods and feed, guidelines and regulations to govern and control the use of GMOs and their products have been enacted. These regulations necessitated the design of methods to detect and analyse the presence of GMOs or their products in agriculture produce, food and feed production chains. Design of techniques and instruments that would detect, identify, and quantify GM ingredients in food and feed will help inspection authorities to relay reliable information to consumers who might be concerned about the presence of GM ingredients. Information generated by detection of GMOs in food and feed would be helpful for setting regulations that govern the use of GM components as well as for labeling purposes. Qualitative detection methods of GM-DNA sequences in foods and feeds have evolved fast during the past few years. There is continuous need for the development of more advanced multi-detection systems and for periodic updates of the databases related to these systems. Testing and Analysis of GMO-containing Foods and Feed presents updates and comprehensive views on the various methods and techniques in use today for the detection, identification and quantification of GMOs in foods and feed. The eleven book chapters cover recent developments on sample preparation techniques, immunoassays methods and the PCR technique used in GMO analysis, the use of biosensors in relation to GMO analysis, the application of nucleic acid microarrays for the detection of GMOs, validation and standardization methods for GMO testing, in addition to the type of reference material and reference methods used in GMO testing and analysis. Some of the ISO standards designed for identifying and detecting the presence of GM material in foods are also presented in the book.
Book Synopsis Guidelines for Laboratory Quality Managers by : Saverio Mannino
Download or read book Guidelines for Laboratory Quality Managers written by Saverio Mannino and published by Springer Nature. This book was released on 2022-11-22 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This useful and extensive set of guidelines is designed to assist food control laboratories in gaining accreditation from an internationally recognized external body, providing all of the necessary information and practices in an easy-to-read, step-by-step fashion. Authored by an experienced consultant for laboratory accreditation in many different countries, with this text food control lab owners now have all of the up-to-date information they need to gain accreditation in a single source. Guidelines for Laboratory Quality Managers covers the essentials for quality management in the food control laboratory, from testing processes to current quality management systems. The ISO standards for accreditation are extensively explored, including managerial requirements, organizational aspects, complaint handling procedures, internal audits, and sampling. An entire section is dedicated to the implementation of managerial and technical requirements from quality control to program monitoring and evaluation. Analysis selection, preparation, and validation is covered extensively, and an entire section is dedicated to basic statistics from data presentation to distribution. Each section comes with helpful tips for lab managers plus definitions and terms. Comprehensive, easy-to-use and up-to-date, Guidelines for Laboratory Quality Managers is the guide for accreditation for food control laboratories.
Book Synopsis How to Reliably Test for GMOs by : Jana Žel
Download or read book How to Reliably Test for GMOs written by Jana Žel and published by Springer Science & Business Media. This book was released on 2011-10-26 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: The detection of genetically modified organisms (GMOs) is becoming very complex, with new GMOs, approved and unapproved, constantly entering world markets. Traceability and labelling of GMOs is defined in regulations worldwide, demanding accurate and reliable testing to support the requirements of legislation. This Brief provides the current state-of-the-art on all key topics involved in GMO testing and is a source of detailed practical information for laboratories. Special focus is given to qualitative and quantitative real-time PCR analysis relevant to all areas where detection and identification rely on nucleic acid-based methods. The following topics, important for testing laboratories, are also discussed: organization of the laboratory, focusing on aspects of the quality system and methods for testing, validation and verification of methods, and measurement uncertainty. The Brief also discusses the new challenges of GMOs and novel modified organisms, using new technologies, and the possible solutions for GMO detection, including bioinformatics tools. Finally, legislation on GMOs and sources of information on GMOs are provided, which are relevant not only to testing laboratories, but to anyone interested in GMOs. The authors of this Brief have many years of experience in GMO testing, development of real-time PCR methods, implementation of quality system requirements, validations and verification of methods, and measurement uncertainty. The National Institute of Biology is a highly qualified research laboratory and a National Reference Laboratory, which also performs routine analyses of food, feed and seed. The Institute for Health and Consumer Protection of the European Union Joint Research Centre has extensive knowledge and experience of GMO detection. It hosts the European Union Reference Laboratory for GM Food and Feed in addition to chairing the European Network of GMO Laboratories.
Book Synopsis New Analytical Approaches for Verifying the Origin of Food by : Paul Brereton
Download or read book New Analytical Approaches for Verifying the Origin of Food written by Paul Brereton and published by Elsevier. This book was released on 2013-07-31 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food and beverage labels often specify a product's geographical origin, species, variety and method of production. These claims can significantly influence an item's economic value, but their verification is not always straightforward. New analytical approaches for verifying the origin of food reviews new analytical methods in this area together with applications to key commodities.Part one introduces the concept of food origin and provides supporting information on labelling legislation and standards. Part two moves on to explore new approaches for verifying the geographical origin of food using geospatial models and verifying species and varietal components of the food we eat. Holistic methods of verification methods using vibrational spectroscopy and associated chemometrics are also discussed. Finally, part three highlights the applications of new analytical methods to verify the origin of particular food commodities: fish, honey and wine.New analytical approaches for verifying the origin of food is a standard reference for professionals working in analytical laboratories testing food authenticity and for researchers, in the food industry, analytical laboratories and academia, working on the development of analytical methods for food authenticity. - Includes a chapter on origin labelling legislation and standards - Chapters address the applications of both established and novel methods in key product sectors - Reviews new analytical methods and their applications in the food industry
Book Synopsis DNA Techniques to Verify Food Authenticity by : Malcolm Burns
Download or read book DNA Techniques to Verify Food Authenticity written by Malcolm Burns and published by Royal Society of Chemistry. This book was released on 2019-10-16 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: The food supply chain needs to reassure consumers and businesses about the safety and standards of food. Global estimates of the cost of food fraud to economies run into billions of dollars hence a huge surge in interest in food authenticity and means of detecting and preventing food fraud and food crime. Approaches targeting DNA markers have assumed a pre-eminence. This book is the most comprehensive and timely collection of material from those working at the forefront of DNA techniques applied to food authenticity. Addressing the new field of analytical molecular biology as it combines the quality assurance rigour of analytical chemistry with DNA techniques, it introduces the science behind DNA as a target analyte, its extraction, amplification, detection and quantitation as applied to the detection of food fraud and food crime. Making the link with traditional forensic DNA profiling and describing emerging and cutting-edge techniques such as next generation sequencing, this book presents real-world case studies from a wide perspective including from analytical service providers, industry, enforcement agencies and academics. It will appeal to food testing laboratories worldwide, who are just starting to use these techniques and students of molecular biology, food science and food integrity. Food policy professionals and regulatory organisations who will be using these techniques to back up legislation and regulation will find the text invaluable. Those in the food industry in regulatory and technical roles will want to have this book on their desks.
Book Synopsis Genetically Modified Organisms in Developing Countries by : Ademola A. Adenle
Download or read book Genetically Modified Organisms in Developing Countries written by Ademola A. Adenle and published by Cambridge University Press. This book was released on 2017-06-09 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides expertly written guidance on the regulation of genetically modified organisms (GMOs) in developing countries, including recommendations about risk analysis and governance.
Book Synopsis Food Chain Integrity by : Jeffrey Hoorfar
Download or read book Food Chain Integrity written by Jeffrey Hoorfar and published by Elsevier. This book was released on 2011-03-15 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improving the integrity of the food chain, making certain that food is traceable, safe to eat, high quality and genuine requires new diagnostic tools, the implementation of novel information systems and input from all food chain participants. Food chain integrity reviews key research in this fast-moving area and how it can be applied to improve the provision of food to the consumer.Chapters in part one review developments in food traceability, such as food 'biotracing', and methods to prevent food bioterrorism. Following this, part two focuses on developments in food safety and quality management. Topics covered include advances in understanding of pathogen behaviour, control of foodborne viruses, hazard ranking and the role of animal feed in food safety. Chapters in part three explore essential aspects of food authenticity, from the traceability of genetically modified organisms in supply chains to new methods to demonstrate food origin. Finally, part four focuses on consumer views on food chain integrity and future trends.With its distinguished editors and expert team of contributors, Food chain integrity is a key reference for all those tasked with predicting and implementing actions to prevent breaches in the integrity of food production. - Reviews key research in this fast-moving area and how it can be applied to improve the provision of food to the consumer - Examines developments in food traceability, such as food 'biotracing', and methods to prevent food bioterrorism - Focuses on developments in food safety and quality management featuring advances in understanding pathogen behaviour and control of foodborne viruses
Download or read book Gene Flow written by Wei Wei and published by CABI. This book was released on 2021-11-02 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene flow is a natural process that occurs spontaneously and enables the evolution of life. However, with the release of genetically modified organisms, concerns have focused on introduced foreign transgenes and their dispersal in nature through gene flow. This book examines gene flow of transgenes, such as herbicide resistance genes, with the goal of understanding the factors that may affect the process of gene flow. A greater biological understanding is essential to make sound management regulatory decisions when also taking into consideration the processes that happen in conventional plants. Monitoring, modelling, and mitigation are the three most closely related elements of gene flow. The book includes both scientific reviews and perspectives on gene flow and experimental case studies, including studies of gene flow in soybean and poplar. The authors present diverse views and research methodologies to understand transgene flow.
Book Synopsis Application of Sampling and Detection Methods in Agricultural Plant Biotechnology by : Ray Shillito
Download or read book Application of Sampling and Detection Methods in Agricultural Plant Biotechnology written by Ray Shillito and published by Elsevier. This book was released on 2022-07-30 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Application of Sampling and Detection Methods in Agricultural Plant Biotechnology describes detection methods for seed, plants and grain derived from biotechnology. This international handbook, based on a series of workshops carried out for governments in collaboration with ILSI and Co-published in partnership with the Cereals & Grains Association, provides the technical and practical information needed to develop, validate and use detection methods. This useful resource provides readers with the tools necessary to carry out reliable sampling, detection and interpretation of data. - Presents a review of the technologies and approaches used for sampling and detecting biotechnology products in seed, plants, grain, food and feed - Serves as a GM detection manual for international regulators and government agencies, testing laboratories, and academic and industrial professionals - Contains case studies, applications, literature reviews and coverage of recent developments
Book Synopsis Genetically Modified and non-Genetically Modified Food Supply Chains by : Yves Bertheau
Download or read book Genetically Modified and non-Genetically Modified Food Supply Chains written by Yves Bertheau and published by John Wiley & Sons. This book was released on 2012-09-10 with total page 967 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the European Union nations, and other countries including Japan, Australia and Malaysia, it is a legal requirement that food products containing genetically modified organism (GMO) materials are labelled as such in order that customers may make informed purchasing decisions. For manufacturers and consumers to be confident about these assertions, systems must be in place along the entire food chain which support the co-existence of GM and non GM materials whilst maintaining a strict segregation between the two. This book is an output of a European Union-funded project entitled "Co-Extra: GM and non-GM food and feed supply chains: their Co-Existence and Traceability". The objective of this four year project is to provide practical tools and methods for implementing co-existence that will: enable the co-existence of genetically modified (GM) and non-GM crops enable the segregation and tracing of genetically modified organism (GMO) materials and derived products along the food and feed chains anticipate the future expansion of the use of GMOs The project is designed to foster a robustly science-based debate amongst all of the stakeholders involved in the food and feed chains, and the tools will be assessed not only from a technical point of view but with regard to the economic and legal aspects. It also surveys the GMO-related legal regimes and practices that exist in and beyond the EU. This book examines the practical tools and methods available to implement the co-existence and traceability of GM and non-GM food materials along the entire food and feed chains, as demanded by consumers and by legislation in force in the EU and elsewhere. GM and Non-GM Supply Foods is a source of valuable information for food manufacturers, food research institutions and regulatory bodies internationally.
Book Synopsis Guidance Document on Measurement Uncertainty for GMO Testing Laboratories by :
Download or read book Guidance Document on Measurement Uncertainty for GMO Testing Laboratories written by and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This document provides guidance on how to estimate measurement uncertainty (MU) and supports the enforcement of EU food and feed labelling legislation in the GMO sector. Measurement uncertainty is a parameter which is always associated with the result of a measurement, and characterises the dispersion of values attributed to that result. This measurement uncertainty needs to be estimated when compliance is investigated. The first version of this guidance document was written on request of the European Network of GMO Laboratories (ENGL) as a follow-up to a workshop on MU in the GMO sector organised by the European Commission, Joint Research Centre and was published in 2007. It was updated in 2009. The current version takes into account current EU legislation, availability of certified reference materials (CRMs) and validated quantification methods and the need for control laboratories which carry out measurements for the enforcement of EU legislation to be accredited according to ISO/IEC 17025. This guidance document contributes towards a harmonised approach for how EU Member States check compliance of food and feed samples with EU legislation. Other documents, e.g. the flexible scope accreditation document refer to this document concerning aspects related to MU.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309452058 Total Pages :231 pages Book Rating :4.3/5 (94 download)
Book Synopsis Preparing for Future Products of Biotechnology by : National Academies of Sciences, Engineering, and Medicine
Download or read book Preparing for Future Products of Biotechnology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-07-28 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of biotechnology be over the next 5â€"10 years? What scientific capabilities, tools, and/or expertise may be needed by the regulatory agencies to ensure they make efficient and sound evaluations of the likely future products of biotechnology? Preparing for Future Products of Biotechnology analyzes the future landscape of biotechnology products and seeks to inform forthcoming policy making. This report identifies potential new risks and frameworks for risk assessment and areas in which the risks or lack of risks relating to the products of biotechnology are well understood.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309437873 Total Pages :231 pages Book Rating :4.3/5 (94 download)
Book Synopsis Gene Drives on the Horizon by : National Academies of Sciences, Engineering, and Medicine
Download or read book Gene Drives on the Horizon written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-08-28 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.
Author :United States. Food and Drug Administration. Division of Microbiology Publisher : ISBN 13 : Total Pages :180 pages Book Rating :4.F/5 ( download)
Book Synopsis Bacteriological Analytical Manual by : United States. Food and Drug Administration. Division of Microbiology
Download or read book Bacteriological Analytical Manual written by United States. Food and Drug Administration. Division of Microbiology and published by . This book was released on 1969 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mutagenic Impurities by : Andrew Teasdale
Download or read book Mutagenic Impurities written by Andrew Teasdale and published by John Wiley & Sons. This book was released on 2022-02-15 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to implement effective control measures for mutagenic impurities in pharmaceutical development In Mutagenic Impurities: Strategies for Identification and Control, distinguished chemist Andrew Teasdale delivers a thorough examination of mutagenic impurities and their impact on the pharmaceutical industry. The book incorporates the adoption of the ICH M7 guideline and focuses on mutagenic impurities from both a toxicological and analytical perspective. The editor has created a primary reference for any professional or student studying or working with mutagenic impurities and offers readers a definitive narrative of applicable guidelines and practical, tested solutions. It demonstrates the development of effective control measures, including chapters on the purge tool for risk assessment. The book incorporates a discussion of N-Nitrosamines which was arguably the largest mutagenic impurity issue ever faced by the pharmaceutical industry, resulting in the recall of Zantac and similar drugs resulting from N-Nitrosamine contamination. Readers will also benefit from the inclusion of: A thorough introduction to the development of regulatory guidelines for mutagenic and genotoxic impurities, including a historical perspective on the development of the EMEA guidelines and the ICH M7 guideline An exploration of in silico assessment of mutagenicity, including use of structure activity relationship evaluation as a tool in the evaluation of the genotoxic potential of impurities A discussion of a toxicological perspective on mutagenic impurities, including the assessment of mutagenicity and examining the mutagenic and carcinogenic potential of common synthetic reagents Perfect for chemists, analysts, and regulatory professionals, Mutagenic Impurities: Strategies for Identification and Control will also earn a place in the libraries of toxicologists and clinical safety scientists seeking a one-stop reference on the subject of mutagenic impurity identification and control.
Author :International Finance Corporation Publisher :World Bank Publications ISBN 13 :1464815496 Total Pages :487 pages Book Rating :4.4/5 (648 download)
Book Synopsis Food Safety Handbook by : International Finance Corporation
Download or read book Food Safety Handbook written by International Finance Corporation and published by World Bank Publications. This book was released on 2020-07-06 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Food Safety Handbook: A Practical Guide for Building a Robust Food Safety Management System, contains detailed information on food safety systems and what large and small food industry companies can do to establish, maintain, and enhance food safety in their operations. This new edition updates the guidelines and regulations since the previous 2016 edition, drawing on best practices and the knowledge IFC has gained in supporting food business operators around the world. The Food Safety Handbook is indispensable for all food business operators -- anywhere along the food production and processing value chain -- who want to develop a new food safety system or strengthen an existing one.
Book Synopsis Safety Considerations for Biotechnology by : Organisation for Economic Co-operation and Development
Download or read book Safety Considerations for Biotechnology written by Organisation for Economic Co-operation and Development and published by OECD. This book was released on 1993 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:
