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Download or read book GTPases in Biology II written by and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642783457
Total Pages : 638 pages
Book Rating : 4.6/5 (427 download)
Download or read book GTPases in Biology II written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: The GTPase switch appears to be almost as old as life itself, and nature has adapted it to a variety of purposes. This two-volume work surveys the major classes of GTPases, including their role in ensuring accuracy during protein translation, a new look at the trimeric G-protein cycle, the molecular function of ARF in vesicle coating, the emerging role of the dynamin family in vesicle transfer, GTPases which activate GTPases during nascent protein translocation, and the many roles of ras-related proteins in growth, cytoskeletal polymerization, and vesicle transfer. 80 chapters contain much previously unpublished data and, at the rate the extended family of GTPases is growing, it is unlikely that it will again sit for a group portrait such as this. Thus, this could well become the standard reference work.
Author : Burton F. Dickey
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (61 download)
Download or read book GTPases in Biology 2 written by Burton F. Dickey and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642782671
Total Pages : 708 pages
Book Rating : 4.6/5 (427 download)
Download or read book GTPases in Biology I written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: The GTPase switch appears to be almost as old as life itself, and nature has adapted it to a variety of purposes. This two-volume work surveys the major classes of GTPases, including their role in ensuring accuracy during protein translation, a new look at the trimeric G-protein cycle, the molecular function of ARF in vesicle coating, the emerging role of the dynamin family in vesicle transfer, GTPases which activate GTPases during nascent protein translocation, and the many roles of ras-related proteins in growth, cytoskeletal polymerization, and vesicle transfer. 80 chapters contain much previously unpublished data and, at the rate the extended family of GTPases is growing, it is unlikely that it will again sit for a group portrait such as this. Thus, this could well become the standard reference work.
Author :
Publisher :
ISBN 13 :
Total Pages : 617 pages
Book Rating : 4.:/5 (91 download)
Download or read book GTPases in Biology written by and published by . This book was released on 1993 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alfred Wittinghofer
Publisher : Springer
ISBN 13 : 3319077619
Total Pages : 299 pages
Book Rating : 4.3/5 (19 download)
Download or read book Ras Superfamily Small G Proteins: Biology and Mechanisms 2 written by Alfred Wittinghofer and published by Springer. This book was released on 2014-09-26 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second of two volumes discusses subfamily proteins which function in molecular and vesicular transport mechanisms inside the cell. In this volume the focus lies on the Rab, Ran and Arf subfamily members. As in Volume 1, the book is written by international renowned scientists in the field of small G-proteins. In elaborate reviews, biochemistry, structure, function and G-protein - effector interactions are described. Together with Volume 1 this book provides an comprehensive state-of-the-art work on small G-proteins (GTPases). It is written for Graduates and Professors in Biochemistry and Cell Biology interested in the mechanism and function of small G-proteins but are extremely valuable for those who want to move into the field.
Author : Fort Philippe
Publisher : World Scientific
ISBN 13 : 9813228806
Total Pages : 212 pages
Book Rating : 4.8/5 (132 download)
Download or read book Rho Gtpases: Molecular Biology In Health And Disease written by Fort Philippe and published by World Scientific. This book was released on 2017-12-12 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rho GTPases control many aspects of cell physiology. This includes polarity, endo/exocytosis, adhesion, motility, transcriptional activation, cell cycle progression or apoptosis. In view of such pleiotropic activities, Rho-controlled signaling has proven to be of medical relevance, especially in tumorigenesis, disease-associated bone remodeling and infectiology. This book is divided into three parts. Part 1 gives an evolutionary perspective of the Rho family, its atypical members, and an overview of how Rho activity is regulated. Part 2 addresses two important aspects of multicellularity controlled by Rho-dependent pathways, namely, cell-cell interactions and mechanotransduction. It also describes how post-translational modifications control Rho activity and how this is exploited by pathogenic bacteria. Part 3 explores several examples of the variety of pathophysiological processes controlled by Rho signaling, and gives a successful example of translational research, from the inhibition of Rho activation to the development of new molecules against osteoporosis. This updated review on the biology of Rho GTPases is an essential read for molecular and cell biologists. It is also an invaluable guide to post-graduate and medical students who wish to deepen their knowledge in cell biology. Contents: An Historical and Evolutionary PerspectiveAtypical Rho GTPases in Health and DiseaseRegulators of Rho SignalingRho GTPases in Cadherin-Based Cell-Cell InteractionsRho Signaling in MechanotransductionPost-Translational modifications of Rho GTPasesRhoA Mutations in Cancer: Oncogenes or Tumor-SuppressorsModulation of Osteoclast Differentiation and Function by Rho GTPasesRhoGEFs as Therapeutic TargetsEndothelial-Specific Rho GTPase Signaling During Leukocyte Extravasation Readership: Molecular and cell biologists, post-graduate and medical students interested in cell biology. Keywords: Rho GTPases;Signaling Oathways;F-actin;Cytoskeleton;Adhesion;Migration;CancerReview: Key Features: Different integration levels for a better understanding of biological and pathological implications of Rho signalingChapters cover updated and original Rho-controlled aspects of cell biologyContributors are leaders in their fields of research
Author : Alfred Wittinghofer
Publisher : Springer
ISBN 13 : 3709118069
Total Pages : 447 pages
Book Rating : 4.7/5 (91 download)
Download or read book Ras Superfamily Small G Proteins: Biology and Mechanisms 1 written by Alfred Wittinghofer and published by Springer. This book was released on 2014-09-22 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first of two volumes provides a general overview of the genetics, structure, mechanism and regulation of the Ras superfamily proteins and describes in detail the signaling pathways and processes regulated by specific members of this family. The focus of this first volume is on the Rho and Ras subfamily of small G proteins. Renowned scientists provide insights into the biochemistry of the classical and non-classical small G-protein family members, their spatio-temporal regulation, their effectors and their roles in health and disease. Together with Volume 2, this book provides a comprehensive and state-of-the-art work on small G-proteins (GTPases). It is intended for graduates and professors in biochemistry and cell biology already working on small G-proteins (small GTPases), but also offers an extremely valuable resource for those readers who are new to the field.
Author : Manfred Schwab
Publisher : Springer Science & Business Media
ISBN 13 : 3540665277
Total Pages : 1017 pages
Book Rating : 4.5/5 (46 download)
Download or read book Encyclopedic Reference of Cancer written by Manfred Schwab and published by Springer Science & Business Media. This book was released on 2001-10-15 with total page 1017 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive encyclopedic reference provides rapid and focused information about topics of cancer research for the clinical and basic scientist, students and informed laymen. It will be readily accessible, both electronically and in print, such that it will be of value to both the scientific community and the public.
Author : Channing Der
Publisher : Springer
ISBN 13 : 9781402043284
Total Pages : 0 pages
Book Rating : 4.0/5 (432 download)
Download or read book RAS Family GTPases written by Channing Der and published by Springer. This book was released on 2006-09-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1982, Ras proteins have been the subject of intense research investigation by the biomedical research community. The wide interest in Ras has been stimulated for three key reasons. This book features chapters contributed by leading investigators in the field that highlight the current state-of-the art in Ras biochemistry, structure and biology. This book is an excellent reference for students in the biomedical sciences and for investigators in the field.
Author :
Publisher : Elsevier
ISBN 13 : 9780080479392
Total Pages : 848 pages
Book Rating : 4.4/5 (793 download)
Download or read book Regulators and Effectors of Small GTPases: Rho Family written by and published by Elsevier. This book was released on 2006-02-21 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Ras superfamily (>150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl and dynamin involved in vesicle budding/fission. These GTPases act as molecular switches and their activities are controlled by a large number of regulatory molecules that affect either GTP loading (guanine nucleotide exchange factors or GEFs) or GTP hydrolysis (GTPase activating proteins or GAPs). In their active state, they interact with a continually increasing, functionally complex array of downstream effectors. Since the last Methods in Enzymology volume on this topic in 2000, Rho GTPases have continued to receive a huge amount of attention. The human genome sequence has revealed the full extent of the Rho GEF and Rho GAP families (over 80 members for each) and the challenge of identifying the molecular interactions and cellular pathways influenced by each of these regulators is a daunting prospect. This new volume, Regulators and Effectors of Small GTPases: Rho Family, describes some of the methods currently being used to examine Rho family GTPase regulation at the biochemical and cellular level. Describes the methods currently being used to examine Rho family GTPase regulation at the biochemical and cellular levels Includes new imaging techniques that revolutionize the ability to visualize GTPase activities Over 150 international contributors
Author : Richard A. Kahn
Publisher : Springer Science & Business Media
ISBN 13 : 1402017197
Total Pages : 368 pages
Book Rating : 4.4/5 (2 download)
Download or read book ARF Family GTPases written by Richard A. Kahn and published by Springer Science & Business Media. This book was released on 2004-02-29 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the first time experts in the area of signalling research with a focus on the ARF family have contributed to the production of a title devoted to ARF biology. A comprehensive phylogenetic analysis of the ARF family, tables of the ARF GEFs and ARF GAPs, and more than a dozen chapters describing them in detail are provided. The impact of the ARF proteins on widely diverse aspects of cell biology and cell signalling can be clearly seen from the activities described; including membrane traffic, lipid metabolism, receptor desensitization, mouse development, microtubule dynamics, and bacterial pathogenesis. Anyone interested in understanding the complexities of cell signalling and the integration of signalling networks will benefit from this volume.
Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Joan Marsh
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 310 pages
Book Rating : 4.3/5 (91 download)
Download or read book The GTPase Superfamily written by Joan Marsh and published by John Wiley & Sons. This book was released on 1993-09-21 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a multidisciplinary approach, it features contributions and discussions of the latest research from leading scientists working on all aspects of GTPase activity. Covers all known members of the important superfamily of enzymes--the GTPases. Considers numerous key cellular functions and how they are regulated by GTPases. Also describes various regulatory proteins that modulate GTPase activity.
Author : Patrice Boquet
Publisher : Springer Science & Business Media
ISBN 13 : 9783540238652
Total Pages : 216 pages
Book Rating : 4.2/5 (386 download)
Download or read book Bacterial Virulence Factors and Rho GTPases written by Patrice Boquet and published by Springer Science & Business Media. This book was released on 2005-04-01 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathogenic bacteria for human and animals have developed sophisticated weapons, termed virulence factors, to ensure their replication and persistence into their hosts. The authors in this volume show a synthesis on how the various host cellular Rho GTPases activities are manipulated by bacteria to fulfil their virulence.
Author : Alfred Wittinghofer
Publisher : Springer
ISBN 13 : 9783319077604
Total Pages : 0 pages
Book Rating : 4.0/5 (776 download)
Download or read book Ras Superfamily Small G Proteins: Biology and Mechanisms 2 written by Alfred Wittinghofer and published by Springer. This book was released on 2014-10-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second of two volumes discusses subfamily proteins which function in molecular and vesicular transport mechanisms inside the cell. In this volume the focus lies on the Rab, Ran and Arf subfamily members. As in Volume 1, the book is written by international renowned scientists in the field of small G-proteins. In elaborate reviews, biochemistry, structure, function and G-protein - effector interactions are described. Together with Volume 1 this book provides an comprehensive state-of-the-art work on small G-proteins (GTPases). It is written for Graduates and Professors in Biochemistry and Cell Biology interested in the mechanism and function of small G-proteins but are extremely valuable for those who want to move into the field.
Author :
Publisher : Elsevier
ISBN 13 : 008049692X
Total Pages : 813 pages
Book Rating : 4.0/5 (84 download)
Download or read book G Protein Pathways, Part B: G Proteins and Their Regulators written by and published by Elsevier. This book was released on 2001-12-18 with total page 813 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers topics such as the structure and identification of functional domains of G proteins, and activation of G proteins by receptors or other regulators. The text takes an integrated approach to studying common experimental questions at many different levels related to G proteins. Methods related to G proteins using molecular modeling, systems biology, protein engineering, protein biochemistry, cell biology, and physiology are all accessible in the same volume. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today truly an essential publication for researchers in all fields of life sciences.
