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Gpi Membrane Anchors
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Download or read book GPI Membrane Anchors written by M Almeida and published by Academic Press. This book was released on 2012-12-02 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: GPI Membrane Anchors reviews major advances in our understanding of glycosylphosphatidylinositol (GPI) membrane anchors. The book examines the GPI structure and its originality as an anchoring device, its ubiquitous distribution, the main steps of its biosynthetic pathway, and the elegant means by which a protein signals for GPI attachment. It also presents evidence for the uniqueness of GPI as a tag in intracellular traffic and as a mediator of transmembrane signaling. This volume is organized into 20 chapters and begins with a discussion of the structural requirements of a nascent protein for processing to a PI-G anchored form, with emphasis on experiments on intact cells and cell-free systems. It then turns to the mechanisms underlying signal transduction by GPI-anchored membrane proteins, the LY-6 superfamily of GPI-anchored molecules, and glycosylated-phosphatidylinositols as virulence factors in Leishmania. The reader is also introduced to the molecular biology of GPI-anchored border hydrolases, the role of GPIs and their inositolglycan derivatives in the mediation of insulin and growth factor function, and biosynthesis and cellular localization of GPI-modified glycoproteins in Saccharomyces cerevisiae. An account of electrospray mass spectrometry of a C-terminal peptide purified from the scrapie isoform of the scrapie prion protein is also given. The book concludes with a chapter on GPI-anchored recognition molecules that function in axonal fasciculation, growth, and guidance in the nervous system. This book is a valuable resource for students and researchers in the fields of cell biology and biochemistry.
Book Synopsis ADP-ribosylation in Animal Tissues by : Friedrich Haag
Download or read book ADP-ribosylation in Animal Tissues written by Friedrich Haag and published by Springer Science & Business Media. This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Documents the first conference on the topic, called in response to opportunities opened by the molecular characterization of the first mammalian mono(ADP-ribosyl)transferase enzyme from rabbit skeletal muscles, and the subsequent realization that one had already been to hand in a well-studied surfac
Book Synopsis Glycosylphosphatidylinositol (GPI) Anchoring of Proteins by : Anant Kumar Menon
Download or read book Glycosylphosphatidylinositol (GPI) Anchoring of Proteins written by Anant Kumar Menon and published by Academic Press. This book was released on 2009-07-09 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of The Enzymes features high-caliber thematic articles on the topic of glycosylphosphatidylinositol (GPI) anchoring of proteins. - Contributions from leading authorities - Informs and updates on all the latest developments in the field
Book Synopsis Essentials of Glycobiology by : Ajit Varki
Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Book Synopsis GPI Membrane Anchors by : M. Lucia Cardoso de Almedia
Download or read book GPI Membrane Anchors written by M. Lucia Cardoso de Almedia and published by . This book was released on 1992 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis GPI Membrane Anchors-The Much Needed Link by : John A. Dangerfield
Download or read book GPI Membrane Anchors-The Much Needed Link written by John A. Dangerfield and published by Bentham Science Publishers. This book was released on 2010-07-08 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Ebook aims to review basic understandings and give current opinions about several important aspects of glycosylphosphatidylinositol-anchored (GPI) protein biology from leading experts in this exciting and emerging field. the scope ranges from micro-domain localization and signaling to proteomics aspects, biophysical behavior through trans-cellular mobility to chemical synthesis of GPI mimics and finally modification of multi-scaled membrane surfaces and potential medical and biotech uses. the applied slant makes it very useful to the current state of knowledge. It is hoped that it will prove to be of considerable interest to students and researchers in this field.
Download or read book Lipid Domains written by and published by Academic Press. This book was released on 2015-06-08 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Membranes is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume offers an up to date presentation of current knowledge in the field of Lipid Domains. - Written by leading experts - Contains original material, both textual and illustrative, that should become a very relevant reference material - The material is presented in a very comprehensive manner - Both researchers in the field and general readers should find relevant and up-to-date information
Book Synopsis The Fungal Cell Wall by : Jean-Paul Latgé
Download or read book The Fungal Cell Wall written by Jean-Paul Latgé and published by Springer Nature. This book was released on 2020-08-12 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates, that the fungal cell wall is critical for the biology and ecology of all fungi and especially for human fungal pathogens. Readers will learn, that the composition of the fungal cell wall is a unique structure, which cannot be found in the human host. Consequently, the chapters outline, how the immune systems of both animals and humans have evolved to recognize conserved and unique elements of the fungal cell wall. As an application example, the authors also show, that the three-dimensional structures of the cell wall are excellent targets for the development of antifungal agents and chemotherapeutic strategies. With the combination of biological findings and medical outlooks, this volume is a fascinating read for scientists, clinicians and biomedical students.
Download or read book Yeast written by Horst Feldmann and published by John Wiley & Sons. This book was released on 2012-09-06 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finally, a stand-alone, all-inclusive textbook on yeast biology. Based on the feedback resulting from his highly successful monograph, Horst Feldmann has totally rewritten he contents to produce a comprehensive, student-friendly textbook on the topic. The scope has been widened, with almost double the content so as to include all aspects of yeast biology, from genetics via cell biology right up to biotechnology applications. The cell and molecular biology sections have been vastly expanded, while information on other yeast species has been added, with contributions from additional authors. Naturally, the illustrations are in full color throughout, and the book is backed by a complimentary website. The resulting textbook caters to the needs of an increasing number of students in biomedical research, cell and molecular biology, microbiology and biotechnology who end up using yeast as an important tool or model organism.
Book Synopsis Membrane Organization and Dynamics by : Amitabha Chattopadhyay
Download or read book Membrane Organization and Dynamics written by Amitabha Chattopadhyay and published by Springer. This book was released on 2017-12-06 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together information on membrane organization and dynamics from a variety of spectroscopic, microscopic and simulation approaches, spanning a broad range of time scales. The implication of such dynamic information on membrane function in health and disease is a topic of contemporary interest. The chapters cover various aspects of membrane lipid and protein dynamics, explored using a battery of experimental and theoretical approaches. The synthesis of information and knowledge gained by utilizing multiple approaches will provide the reader with a comprehensive understanding of the underlying membrane dynamics and function, which will help to develop robust dynamic models for the understanding of membrane function in healthy and diseased states. In the last few years, crystal structures of an impressive number of membrane proteins have been reported, thanks to tremendous advances in membrane protein crystallization techniques. Some of these recently solved structures belong to the G protein-coupled receptor (GPCR) family, which are particularly difficult to crystallize due to their intrinsic flexibility. Nonetheless, these static structures do not provide the necessary information to understand the function of membrane proteins in the complex membrane milieu. This volume will address the dynamic nature of membrane proteins within the membrane and will provide the reader with an up-to date overview of the theory and practical approaches that can be used. This volume will be invaluable to researchers working in a wide range of scientific areas, from biochemistry and molecular biology to biophysics and protein science. Students of these fields will also find this volume very useful. This book will also be of great use to those who are interested in the dynamic nature of biological processes.
Book Synopsis The Plant Plasma Membrane by : Angus S. Murphy
Download or read book The Plant Plasma Membrane written by Angus S. Murphy and published by Springer Science & Business Media. This book was released on 2010-11-11 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: In plant cells, the plasma membrane is a highly elaborated structure that functions as the point of exchange with adjoining cells, cell walls and the external environment. Transactions at the plasma membrane include uptake of water and essential mineral nutrients, gas exchange, movement of metabolites, transport and perception of signaling molecules, and initial responses to external biota. Selective transporters control the rates and direction of small molecule movement across the membrane barrier and manipulate the turgor that maintains plant form and drives plant cell expansion. The plasma membrane provides an environment in which molecular and macromolecular interactions are enhanced by the clustering of proteins in oligimeric complexes for more efficient retention of biosynthetic intermediates, and by the anchoring of protein complexes to promote regulatory interactions. The coupling of signal perception at the membrane surface with intracellular second messengers also involves transduction across the plasma membrane. Finally, the generation and ordering of the external cell walls involves processes mediated at the plant cell surface by the plasma membrane. This volume is divided into three sections. The first section describes the basic mechanisms that regulate all plasma membrane functions. The second describes plasma membrane transport activity. The final section of the book describes signaling interactions at the plasma membrane. These topics are given a unique treatment in this volume, as the discussions are restricted to the plasma membrane itself as much as possible. A more complete knowledge of the plasma membrane’s structure and function is essential to current efforts to increase the sustainability of agricultural production of food, fiber, and fuel crops.
Book Synopsis Microbial Glycobiology by : Anthony P Moran
Download or read book Microbial Glycobiology written by Anthony P Moran and published by Elsevier. This book was released on 2009-10-01 with total page 1037 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents in an easy-to-read format a summary of the important central aspects of microbial glycobiology, i.e. the study of carbohydrates as related to the biology of microorganisms. Microbial glycobiology represents a multidisciplinary and emerging area with implications for a range of basic and applied research fields, as well as having industrial, medical and biotechnological implications. - Individual chapters provided by leading international scientists in the field yield insightful, concise and stimulating reviews - Provides researchers with an overview and synthesis of the latest research - Each chapter begins with a brief 200 word Summary/Abstract detailing the topic and focus of the chapter, as well as the concepts to be addressed - Allows researchers to see at a glance what each chapter will cover - Each chapter includes a Research Focus Box - Identifies important problems that still need to be solved and areas that require further investigation
Book Synopsis Carbohydrates: The Essential Molecules of Life by : Robert V. Stick
Download or read book Carbohydrates: The Essential Molecules of Life written by Robert V. Stick and published by Elsevier. This book was released on 2010-08-06 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the "nuts and bolts" background for a successful study of carbohydrates - the essential molecules that not only give you energy, but are an integral part of many biological processes.A question often asked is 'Why do carbohydrate chemistry?' The answer is simple: It is fundamental to a study of biology. Carbohydrates are the building blocks of life and enable biological processes to take place.Therefore the book will provide a taste for the subject of glycobiology.Covering the basics of carbohydrates and then the chemistry and reactions of carbohydrates this book will enable a chemist to gain essential knowledge that will enable them to move smoothly into the worlds of biochemistry, molecular biology and cell biology. - Includes perspective from new co-author Spencer Williams, who enhances coverage of the connection between carbohydrates and life - Describes the basic chemistry and biology of carbohydrates - Reviews the concepts, synthesis, reactions, and biology of carbohydrates
Download or read book Encyclopedia of Malaria written by and published by Springer. This book was released on 2018-07-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Malaria represents a vast databank of information about the study of malaria. It provides an overview of the historical, rapid and significant developments that have occurred in malaria research, including the 2002 genome sequencing of Plasmodium falciparum and its mosquito vector, Anopheles gambiae. This work provides a concise source of up-to-date research findings in the form of definitions and essays and present comprehensive coverage of topics from history to findings to diagnosis and treatment, written by recognized malaria researchers with practical experience. It appeals to a diverse audience, including malaria researchers, teachers, investigators and public health professionals.
Book Synopsis Lipid Rafts and Caveolae by : Christopher J. Fielding
Download or read book Lipid Rafts and Caveolae written by Christopher J. Fielding and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This keenly awaited first overview of the field represents a complete guide to the structure and function of the most important mammalian cell membrane organelles. Filling a huge gap in the primary literature, this book is the first to cover the subject in detail. Following an introduction by Kai Simons, the discoverer of lipid rafts and the most prominent scientist in the field, chapters include: Historical background Distinct structures and functions Structural basis Signaling Viral entry and virion budding Cholesterol transport Caveolins Lipid shells Cell polarity and intracellular trafficking Cancer cells Of prime importance to molecular and cell biologists, biochemists, membrane scientists, cancer researchers, and virologists.
Book Synopsis Prediction of Protein Structure and the Principles of Protein Conformation by : G.D. Fasman
Download or read book Prediction of Protein Structure and the Principles of Protein Conformation written by G.D. Fasman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 796 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prediction of the conformation of proteins has developed from an intellectual exercise into a serious practical endeavor that has great promise to yield new stable enzymes, products of pharmacological significance, and catalysts of great potential. With the application of predic tion gaining momentum in various fields, such as enzymology and immunology, it was deemed time that a volume be published to make available a thorough evaluation of present methods, for researchers in this field to expound fully the virtues of various algorithms, to open the field to a wider audience, and to offer the scientific public an opportunity to examine carefully its successes and failures. In this manner the practitioners of the art could better evaluate the tools and the output so that their expectations and applications could be more realistic. The editor has assembled chapters by many of the main contributors to this area and simultaneously placed their programs at three national resources so that they are readily available to those who wish to apply them to their personal interests. These algorithms, written by their originators, when utilized on pes or larger computers, can instantaneously take a primary amino acid sequence and produce a two-or three-dimensional artistic image that gives satisfaction to one's esthetic sensibilities and food for thought concerning the structure and function of proteins. It is in this spirit that this volume was envisaged.
