Governing Molecules

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Publisher : MIT Press
ISBN 13 : 9780262262781
Total Pages : 418 pages
Book Rating : 4.2/5 (627 download)

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Book Synopsis Governing Molecules by : Herbert Gottweis

Download or read book Governing Molecules written by Herbert Gottweis and published by MIT Press. This book was released on 1998-12-10 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists, investors, policymakers, the media, and the general public have all displayed a continuing interest in the commercial promise and potential dangers of genetic engineering. In this book, Herbert Gottweis explains how genetic engineering became so controversial—a technology that some seek to promote by any means and others want to block entirely. Beginning with a clear exposition of poststructuralist theory and its implications for research methodology, Gottweis offers a novel approach to political analysis, emphasizing the essential role of narratives in the development of policy under contemporary conditions. Drawing on more than eighty in-depth interviews and extensive archival work, Gottweis traces today's controversy back to the sociopolitical and scientific origins of molecular biology, paying particular attention to its relationship to eugenics. He argues that over the decades a number of mutually reinforcing political and scientific strategies have attempted to turn genes into objects of technological intervention—to make them "governable." Looking at critical events such as the 1975 Asilomar conference in the United States, the escalating conflict in Germany, and regulatory disputes in Britain and France during the 1980s, Gottweis argues that it was the struggle over boundaries and representations of genetic engineering, politics, and society that defined the political dynamics of the drafting of risk regulations in these countries. In a key chapter on biotechnology research, industry, and supporting technology policies, Gottweis demonstrates that the interpretation of genetic engineering as the core of a new "high technology" industry was part of a policy myth and an expression of identity politics. He suggests that under postmodern conditions a major strategy for avoiding policy failure is to create conditions that ensure tolerance and respect for the multiplicity of socially available policy narratives and reality interpretations.

Molecular Biology of the Cell

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Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetic and Epigenetic Control on Immune Responses Regulating Molecules in Cancer Development, Progression, and Treatment

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832555896
Total Pages : 299 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Genetic and Epigenetic Control on Immune Responses Regulating Molecules in Cancer Development, Progression, and Treatment by : Katherine Chiappinelli

Download or read book Genetic and Epigenetic Control on Immune Responses Regulating Molecules in Cancer Development, Progression, and Treatment written by Katherine Chiappinelli and published by Frontiers Media SA. This book was released on 2024-10-16 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: In line with recent evidence, the development of cancer has been described as uncontrolled cell growth that results from gradual accumulation of genetic and epigenetic alterations, involving aberrations in oncogenes, tumor suppressor genes, and defects in genes engaged in DNA repair. As a result, cancer cells acquire a neoplastic phenotype and tumor-associated antigens (TAAs) are presented on their surface. These target structures should be recognized by cells of the immune system. However, a sequence of events at the genetic and epigenetic level disturb immune cells, and in consequence, make them unable to eliminate cancer cells. Both innate and adaptive immunity are mobilized against cancer cells. In response to the appearance of cells with malignant transformation, NK cells release perforin and granzyme, causing direct cytolysis of the target cells. They can also secrete pro-inflammatory cytokines and in that way enhance the anticancer response. The activity of NK cells is regulated by a variety of activating and inhibitory receptors including NKG2D, KIR, CD94 -NKG2 heterodimers and natural cytotoxicity receptors, TNF family ligands, as well as co-stimulatory receptors, which recognize related molecules on target cells. A fundamental trigger of the anticancer immune response is the recognition of TAAs by T cells, via the major histocompatibility complex (MHC), which should be followed by signals from co-stimulatory molecules. Full activation of T lymphocytes requires a third signal provided by the presence of cytokines, and this leads to cell proliferation, differentiation, and secretion of chemokines and cytokines. The effect is to drive the clonal expansion of the T cells directed against TAAs and to recruit other immune effector cells in order to enhance immune defense.

Genetic Governance

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Author :
Publisher : Psychology Press
ISBN 13 : 9780415354073
Total Pages : 232 pages
Book Rating : 4.3/5 (54 download)

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Book Synopsis Genetic Governance by : Robin Bunton

Download or read book Genetic Governance written by Robin Bunton and published by Psychology Press. This book was released on 2005 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contributors look at how the 'new' genetics, healthcare and arising health policy can or should be governed and regulated, rather than focusing on individualistic ethical issues, this text takes a broader, international public health approach.

The Race to Commercialize Biotechnology

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Publisher : Routledge
ISBN 13 : 1134456085
Total Pages : 229 pages
Book Rating : 4.1/5 (344 download)

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Book Synopsis The Race to Commercialize Biotechnology by : Steven Collins

Download or read book The Race to Commercialize Biotechnology written by Steven Collins and published by Routledge. This book was released on 2004-07-31 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comparative study looks at the early development of biotechnology in the US and Japan. Drawing on primary and secondary sources it traces the historical roots of recombinant DNA technology, discusses the tensions between regulation and promotional policies and identifies the major actors and strategies that launched biotechnology in both countries. Developing several strands of theory in economic history, science and technology policy, the book proposes a simple model that relates the differences in the two countries' responses to variations in the availability of institutional, financial and organizational resources needed to commercialize the new technology.

Biology, Computing, and the History of Molecular Sequencing

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Author :
Publisher : Springer
ISBN 13 : 0230370934
Total Pages : 253 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Biology, Computing, and the History of Molecular Sequencing by : M. García-Sancho

Download or read book Biology, Computing, and the History of Molecular Sequencing written by M. García-Sancho and published by Springer. This book was released on 2012-05-11 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.

Complex Governance Networks

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Publisher : Taylor & Francis
ISBN 13 : 1000836533
Total Pages : 188 pages
Book Rating : 4.0/5 (8 download)

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Book Synopsis Complex Governance Networks by : Göktuğ Morçöl

Download or read book Complex Governance Networks written by Göktuğ Morçöl and published by Taylor & Francis. This book was released on 2023-02-17 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: What are the roles of governments and other actors in solving, or alleviating, collective action problems in today’s world? The traditional conceptual frameworks of public administration and public policy studies have become less relevant in answering this question. This book critically assesses traditional conceptual frameworks and proposes an alternative: a complex governance networks (CGN) framework. Advocating that complexity theory should be systematically integrated with foundational concepts of public administration and public policy, Göktuğ Morçöl begins by clarifying the component concepts of CGN and then addresses the implications of CGN for key issues in public administration and policy studies: effectiveness, accountability, and democracy. He illustrates the applicability of the CGN concepts with examples for the COVID-19 pandemic and metropolitan governance, particularly the roles of business improvement districts in governance processes. Morçöl concludes by discussing the implications of CGN for the convergence of public administration and public policy education and offering suggestions for future studies using the CGN conceptualization. Complex Governance Networks is essential reading for both scholars and advanced students of public policy, public administration, public affairs, and related areas.

Molecular mechanisms regulating cytotoxic lymphocyte development and function, and their associations to human diseases

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889192792
Total Pages : 164 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Molecular mechanisms regulating cytotoxic lymphocyte development and function, and their associations to human diseases by : Konrad Krzewski

Download or read book Molecular mechanisms regulating cytotoxic lymphocyte development and function, and their associations to human diseases written by Konrad Krzewski and published by Frontiers Media SA. This book was released on 2015-04-22 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nothing provided

Changing Governance of Research and Technology Policy

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Author :
Publisher : Edward Elgar Publishing
ISBN 13 : 9781781957790
Total Pages : 364 pages
Book Rating : 4.9/5 (577 download)

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Book Synopsis Changing Governance of Research and Technology Policy by : Jakob Edler

Download or read book Changing Governance of Research and Technology Policy written by Jakob Edler and published by Edward Elgar Publishing. This book was released on 2003-01-01 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection analyses and comments on the development of the ERA, which seeks to co-ordinate national research and advance European wide projects. The contributors include leading scholars of European integration and technology policy and high-level administrators. They discuss the potential impacts, benefits and limits to research and innovation policy within Europe both in the short and long term. Moreover, the debate about ERA is placed firmly in the context of the overall changes at the European level.

Oversight Hearing on Implementation of NIH Guidelines Governing Recombinant DNA Research

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Publisher :
ISBN 13 :
Total Pages : 164 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Oversight Hearing on Implementation of NIH Guidelines Governing Recombinant DNA Research by : United States. Congress. Senate. Committee on Labor and Public Welfare. Subcommittee on Health

Download or read book Oversight Hearing on Implementation of NIH Guidelines Governing Recombinant DNA Research written by United States. Congress. Senate. Committee on Labor and Public Welfare. Subcommittee on Health and published by . This book was released on 1977 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Philosophical Letters of David K. Lewis

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Publisher : Oxford University Press
ISBN 13 : 0192597876
Total Pages : 480 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis Philosophical Letters of David K. Lewis by : David K. Lewis

Download or read book Philosophical Letters of David K. Lewis written by David K. Lewis and published by Oxford University Press. This book was released on 2020-10-29 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: David Kellogg Lewis (1941-2001) was one of the most influential philosophers of the twentieth century. He made significant contributions to almost every area of analytic philosophy including metaphysics, philosophy of language, philosophy of mind, and philosophy of science, and set the agenda for various debates in these areas which carry on to this day. In several respects he remains a contemporary figure, yet enough time has now passed for historians of philosophy to begin to study his place in twentieth century thought. His philosophy was constructed and refined not just through his published writing, but also crucially through his life-long correspondence with fellow philosophers, including leading figures such as D.M. Armstrong, Saul Kripke, W.V. Quine, J.J.C. Smart, and Peter van Inwagen. His letters formed the undercurrent of his published work and became the medium through which he proposed many of his well-known theories and discussed a range of philosophical topics in depth. A selection of his vast correspondence over a 40-year period is presented here across two volumes. Structured in three parts, Volume 2 explores Lewis' contributions to philosophical questions of mind, language, and epistemology respectively. The letters address Lewis's answer to the mind-body problem, propositional attitudes and the purely subjective character of conscious experience, meaning and reference as well as grammar in language, vagueness, truth in fiction, the problem of scepticism, and Lewis's work on decision theory and rationality, among many other topics. This volume is a testament to Lewis' achievement in these areas and will be an invaluable resource for those exploring contemporary debates concerning mind, language, and epistemology.

Philosophical Letters of David K. Lewis

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Publisher : Oxford University Press, USA
ISBN 13 : 0198855451
Total Pages : 881 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis Philosophical Letters of David K. Lewis by : Helen Beebee

Download or read book Philosophical Letters of David K. Lewis written by Helen Beebee and published by Oxford University Press, USA. This book was released on 2020-11-05 with total page 881 pages. Available in PDF, EPUB and Kindle. Book excerpt: The life-long correspondence of David K. Lewis, one of the most influential philosophers of the twentieth century, reveals the development, breadth, and depth of his philosophy in its historical context. The first of this two volume collection of letters focuses on his contributions to metaphysics, arguably where he made his greatest impact.

Molecular Mechanisms of Synaptogenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 038732562X
Total Pages : 504 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Molecular Mechanisms of Synaptogenesis by : Alexander Dityatev

Download or read book Molecular Mechanisms of Synaptogenesis written by Alexander Dityatev and published by Springer Science & Business Media. This book was released on 2006-11-24 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a new compilation of information that link changes in the basic structure of synapses and brain diseases. The book shows that specific secreted proteins, and short peptide mimicking the function of neural cell adhesion molecules can significantly enhance the formation of synapses in the brain. It describes recent advances in research that lay necessary scientific groundwork to develop pharmacological treatments.

Regulating Next Generation Agri-Food Biotechnologies

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Publisher : Routledge
ISBN 13 : 1136338446
Total Pages : 290 pages
Book Rating : 4.1/5 (363 download)

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Book Synopsis Regulating Next Generation Agri-Food Biotechnologies by : Michael Howlett

Download or read book Regulating Next Generation Agri-Food Biotechnologies written by Michael Howlett and published by Routledge. This book was released on 2013-05-07 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Agri-food bio-technology policy and regulation is transitioning from an early period focused on genetic engineering technologies to ‘next-generation’ rules and regulatory processes linked to challenges originating in a wide variety of new technological processes and applications. Can lessons learned from past and current regulatory oversights of agricultural biotechnology – and other high-technology sectors – help us address new and emerging regulatory challenges in the agri-food genetics sector? The expert contributors in this volume discuss the experiences of a wide range of North American, European and Asian countries with high technology regulation to address four key questions related to the past and future development of agri-food genomics regulation across the globe. how unique is agri-food biotechology regulation, and how can it be evaluated using the existing tools of regulatory analysis developed in examinations of other sectors? is a ‘government to governance’ model of regulatory regime development found in many other sectors relevant in this rapidly evolving sphere of activity? is a stages model of regulatory regime development accurate? And, if so, at which stage are we currently positioned in the regulation of agri-food genomics products and technologies? what drives movement between stages in different countries and sectors? In assessing such drivers, what are the key links between sectoral (meso) developments and more general macro and micro developments such as international relations and administrative behaviour? By updating, extending and challenging earlier empirical and theoretical social science perspectives on agricultural bio-technological regulation, this volume helps to inform future policy formulation. It will be of interest to practitioners and students of biotechnology, agriculture, and science and technology policy, and regulatory processes more generally.

Companion to the History of Modern Science

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Publisher : Routledge
ISBN 13 : 1000158853
Total Pages : 754 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Companion to the History of Modern Science by : G N Cantor

Download or read book Companion to the History of Modern Science written by G N Cantor and published by Routledge. This book was released on 2020-10-07 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 67 chapters of this book describe and analyse the development of Western science from 1500 to the present day. Divided into two major sections - 'The Study of the History of Science' and 'Selected Writings in the History of Science' - the volume describes the methods and problems of research in the field and then applies these techniques to a wide range of fields. Areas covered include: * the Copernican Revolution * Genetics * Science and Imperialism * the History of Anthropology * Science and Religion * Magic and Science. The companion is an indispensable resource for students and professionals in History, Philosophy, Sociology and the Sciences as well as the History of Science. It will also appeal to the general reader interested in an introduction to the subject.

The Business of Global Environmental Governance

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Publisher : MIT Press
ISBN 13 : 9780262621885
Total Pages : 380 pages
Book Rating : 4.6/5 (218 download)

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Book Synopsis The Business of Global Environmental Governance by : David L. Levy

Download or read book The Business of Global Environmental Governance written by David L. Levy and published by MIT Press. This book was released on 2005 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theoretical and empirical accounts of the role of business in shaping international environmental policies.

The Governance of Socio-Technical Systems

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Publisher : Edward Elgar Publishing
ISBN 13 : 1784710199
Total Pages : 226 pages
Book Rating : 4.7/5 (847 download)

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Book Synopsis The Governance of Socio-Technical Systems by : Susana Borrás

Download or read book The Governance of Socio-Technical Systems written by Susana Borrás and published by Edward Elgar Publishing. This book was released on 2014-11-28 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why are so few electric cars in our streets today? Why is it difficult to introduce electronic patient records in our hospitals? To answer these questions we need to understand how state and non-state actors interact with the purpose of transforming so