Glycomimetics

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Glycomimetics

Author : René Roy
Publisher :
ISBN 13 :
Total Pages : 210 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Glycomimetics by : René Roy

Download or read book Glycomimetics written by René Roy and published by . This book was released on 2005 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Synthetic Methodologies Toward Glycomimetics contains 10 chapters describing the syntheses of natural and non-natural glycomimetics using modern transition metal catalyzed reactions. This book also contains several experimental details allowing the readers to get familiar with such intricate reactions using complex alkylidene carbenoids, samarium diodide, dicobalt octacarbonyl alkyne cyclotrimerization, and the like. The descriptions of biologically active carbohydrates are elegantly detailed. A new solution-phase glycopeptide synthesis using unprotected glycosyl amino acids as phase-tags is also described. Important strategies into the design of complex sialic acid C-saccharides, aryl C-glycosides, and conformationally restricted analogs of the important sialyl Lewis X are discussed. Tethering of carbohydrate residues through ester bonds and applications of the Tebbe's methylenation and either ring closing metathesis or intramolecular C-glycosidations are used to provide novel carbohydrate analogs.

The Glycome

Author : Adeel Malik
Publisher : CRC Press
ISBN 13 : 1000344320
Total Pages : 305 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis The Glycome by : Adeel Malik

Download or read book The Glycome written by Adeel Malik and published by CRC Press. This book was released on 2021-07-07 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive understanding of the enigmatic identity of the glycome, a complex but important area of research that has been largely ignored due to its complexity. The authors thoroughly deal with almost all aspects of the glycome, i.e., elucidation of the glycan identity enigma and its role in regulation of the cellular process, and in disease etiology. The book bridges the knowledge gap in understanding the glycome, from being a cell signature to its applications in disease etiology. In addition, it details many of the major insights regarding the possible role of the glycome in various diseases as a therapeutic marker. The book systematically covers the major aspects of the glycome, including the significance of substituting the diverse monosaccharide units to glycoproteins, the role of glycans in disease pathologies, and the challenges and advances in glycobiology. The authors stress the significance and huge encoding power of carbohydrates as well as provide helpful insights in framing the bigger picture. The Glycome: Understanding the Diversity and Complexity of Glycobiology details state-of-the-art developments and emerging challenges of glycome biology, which are going to be key areas of future research, not only in the glycobiology field but also in pharmaceutics.

Company Profiles: GlycoMimetics Inc

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (958 download)

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Book Synopsis Company Profiles: GlycoMimetics Inc by :

Download or read book Company Profiles: GlycoMimetics Inc written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

High-Performance Materials from Bio-based Feedstocks

Author : Andrew J. Hunt
Publisher : John Wiley & Sons
ISBN 13 : 1119655722
Total Pages : 436 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis High-Performance Materials from Bio-based Feedstocks by : Andrew J. Hunt

Download or read book High-Performance Materials from Bio-based Feedstocks written by Andrew J. Hunt and published by John Wiley & Sons. This book was released on 2022-04-04 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: High-Performance Materials from Bio-based Feedstocks The latest advancements in the production, properties, and performance of bio-based feedstock materials In High-Performance Materials from Bio-based Feedstocks, an accomplished team of researchers delivers a comprehensive exploration of recent developments in the research, manufacture, and application of advanced materials from bio-based feedstocks. With coverage of bio-based polymers, the inorganic components of biomass, and the conversion of biomass to advanced materials, the book illustrates the research and commercial potential of new technologies in the area. Real-life applications in areas as diverse as medicine, construction, synthesis, energy storage, agriculture, packaging, and food are discussed in the context of the structural properties of the materials used. The authors offer deep insights into materials production, properties, and performance. Perfect for chemists, environmental scientists, engineers, and materials scientists, High-Performance Materials from Bio-based Feedstocks will also earn a place in the libraries of academics, industrial researchers, and graduate students with an interest in biomass conversion, green chemistry, and sustainability. A thorough introduction to the latest developments in advanced bio-based feedstock materials research Comprehensive explorations of a vast range of real-world applications, from tissue scaffolds and drug delivery to batteries, sorbents, and controlled release fertilizers Practical discussions of the organic and inorganic components of biomass and the conversion of biomass to advanced materials In-depth examinations of the structural properties of commercially and academically significant biomass materials For more information on the Wiley Series in Renewable Resources, visit www.wiley.com/go/rrs

Current Pharmaceutical Design

Author :
Publisher :
ISBN 13 :
Total Pages : 130 pages
Book Rating : 4./5 ( download)

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Book Synopsis Current Pharmaceutical Design by :

Download or read book Current Pharmaceutical Design written by and published by . This book was released on 1995-08 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Microbial Glycobiology

Author : Anthony P Moran
Publisher : Elsevier
ISBN 13 : 0080923240
Total Pages : 1037 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Microbial Glycobiology by : Anthony P Moran

Download or read book Microbial Glycobiology written by Anthony P Moran and published by Elsevier. This book was released on 2009-10-01 with total page 1037 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents in an easy-to-read format a summary of the important central aspects of microbial glycobiology, i.e. the study of carbohydrates as related to the biology of microorganisms. Microbial glycobiology represents a multidisciplinary and emerging area with implications for a range of basic and applied research fields, as well as having industrial, medical and biotechnological implications. - Individual chapters provided by leading international scientists in the field yield insightful, concise and stimulating reviews - Provides researchers with an overview and synthesis of the latest research - Each chapter begins with a brief 200 word Summary/Abstract detailing the topic and focus of the chapter, as well as the concepts to be addressed - Allows researchers to see at a glance what each chapter will cover - Each chapter includes a Research Focus Box - Identifies important problems that still need to be solved and areas that require further investigation

Glycoscience and Microbial Adhesion

Author : Thisbe K. Lindhorst
Publisher : Springer Science & Business Media
ISBN 13 : 3642013031
Total Pages : 194 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Glycoscience and Microbial Adhesion by : Thisbe K. Lindhorst

Download or read book Glycoscience and Microbial Adhesion written by Thisbe K. Lindhorst and published by Springer Science & Business Media. This book was released on 2009-06-23 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: bacterial carbohydrate recognition are conveyed, covering Gram-positive as well as Gram-negative bacteria, in Chapter 4 Streptococci and Staphylococci, and in Chapter 5, carbohydrate binding specificities of Helicobacter pylori. In Chapter 6, "Bitter sweetness of complexity," the collected reflections on mic- bial adhesion are expanded by a perspective on a broader impact of glycosylation on cellular adhesion, motility and regulatory processes, paralleling the complexity of N-glycan structures on cell surfaces. It highlights particularly how structural details of N-glycans have been causally related to pathological scenarios, with a focus on ?(1,6)-N-acetylglucosaminyltransferase. In the final chapter, biofilm formation is reviewed, covering knowledge about structure and biosynthesis of polysaccharide intercellular adhesins (PIAs) which are central to biofilm formation. This comprehensive chapter explains all PIA-related principles of medical device-associated infections. It is our hope, that this collection of expert articles, ranging from structural ch- istry and structural biology to biochemistry and medicine, will be a stimulation and motivation for our colleagues in the life sciences. At the same time, we hope that these reflections on microbial adhesion will awake interest in and promote und- standing of the complex processes associated with the glycocalyx and the multif- eted interactions between the host cell and its "guest," as well as the biological consequences resulting from this mutual interplay.

Special Issue

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (5 download)

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Book Synopsis Special Issue by :

Download or read book Special Issue written by and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Click Chemistry

Author : Vinod K. Tiwari
Publisher : Springer Nature
ISBN 13 : 9819745969
Total Pages : 684 pages
Book Rating : 4.8/5 (197 download)

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Book Synopsis Click Chemistry by : Vinod K. Tiwari

Download or read book Click Chemistry written by Vinod K. Tiwari and published by Springer Nature. This book was released on with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Essentials of Carbohydrate Chemistry and Biochemistry

Author : Thisbe K. Lindhorst
Publisher : John Wiley & Sons
ISBN 13 : 3527315284
Total Pages : 333 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Essentials of Carbohydrate Chemistry and Biochemistry by : Thisbe K. Lindhorst

Download or read book Essentials of Carbohydrate Chemistry and Biochemistry written by Thisbe K. Lindhorst and published by John Wiley & Sons. This book was released on 2007-04-09 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concise yet complete, this is a succinct introduction to the topic, covering both basic chemistry as well as such advanced topics as high-throughput analytics and glycomics -- in one handy volume. This improved and expanded 3rd edition features all-new material on combinatorial synthesis of carbohydrates and carbohydrate biodiversity, and each chapter now contains study questions for self-learning and classroom teaching. Didactically written by an experienced lecturer and graduate student advisor, the text is backed by practical examples and more than 150 study questions tailored to students' needs.

Antiviral Discovery for Highly Pathogenic Emerging Viruses

Author : César Muñoz-Fontela
Publisher : Royal Society of Chemistry
ISBN 13 : 1839160535
Total Pages : 209 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Antiviral Discovery for Highly Pathogenic Emerging Viruses by : César Muñoz-Fontela

Download or read book Antiviral Discovery for Highly Pathogenic Emerging Viruses written by César Muñoz-Fontela and published by Royal Society of Chemistry. This book was released on 2021-11-26 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: New antiviral drugs are urgently needed. Recent outbreaks caused by viruses with great epidemiological impact such as Zika, or extraordinary virulence such as Ebola, Nipah, Lassa, Crimean-Congo haemorrhagic fever highlight the current lack of clinically proven vaccines and treatments for these potentially catastrophic agents. Antiviral Discovery for Highly Pathogenic Emerging Viruses comprehensively outlines the state of the art in antiviral drug discovery including identification of targets, screening strategies and the current pipeline of antiviral candidates including regulatory issues. The book also addresses the challenges faced in proceeding from pre-clinical studies to animal models and clinical trials with these highly pathogenic agents. Ideal for drug discovery scientists and medicinal chemists with an interest in antiviral drug discovery and development, this book provides a complete overview of the latest progress in the field, recent advances and the challenges that remain in developing these highly pathogenic agents. Illustrated throughout with case studies this book is a valuable resource in this complex and multidisciplinary field.

Glycoscience: Chemistry and Chemical Biology I–III

Author : Bertram O. Fraser-Reid
Publisher : Springer Science & Business Media
ISBN 13 : 3642568742
Total Pages : 2817 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Glycoscience: Chemistry and Chemical Biology I–III by : Bertram O. Fraser-Reid

Download or read book Glycoscience: Chemistry and Chemical Biology I–III written by Bertram O. Fraser-Reid and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 2817 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycostructures play a highly diverse and crucial role in a myriad of organisms and systems in biology, physiology, medicine, and bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and chemistry behind them. In this set the editors present up-to-date information on glycostructures, their chemistry and chemical biology, in the form of a comprehensive survey. The text is accompanied by over 2000 figures, chemical structures and reaction schemes and more than 9000 references. The accompanying CD-ROM enables, besides text searches, searches for structures, schemes, and other information.

Transforming Glycoscience

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309260868
Total Pages : 171 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Transforming Glycoscience by : National Research Council

Download or read book Transforming Glycoscience written by National Research Council and published by National Academies Press. This book was released on 2012-10-23 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new focus on glycoscience, a field that explores the structures and functions of sugars, promises great advances in areas as diverse as medicine, energy generation, and materials science, this report finds. Glycans-also known as carbohydrates, saccharides, or simply as sugars-play central roles in many biological processes and have properties useful in an array of applications. However, glycans have received little attention from the research community due to a lack of tools to probe their often complex structures and properties. Transforming Glycoscience: A Roadmap for the Future presents a roadmap for transforming glycoscience from a field dominated by specialists to a widely studied and integrated discipline, which could lead to a more complete understanding of glycans and help solve key challenges in diverse fields.

Carbohydrates 2018

Author : Amélia Pilar Rauter
Publisher : MDPI
ISBN 13 : 3039283162
Total Pages : 172 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Carbohydrates 2018 by : Amélia Pilar Rauter

Download or read book Carbohydrates 2018 written by Amélia Pilar Rauter and published by MDPI. This book was released on 2020-03-25 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains original papers and reviews on carbohydrate research in medicine, authored by participants of the 29th International Carbohydrate Symposium, where this topic had a special emphasis. The focus on biological events involving carbohydrates and glycoconjugates has delivered reliable approaches for disease treatment and diagnosis. Research on carbohydrate-based compounds for therapeutic applications is illustrated in various contributions, namely those covering the development of novel agents against Alzheimer’s disease, e.g. the neuroprotective C-glucosylated flavones and the isonucleoside-based cholinesterase inhibitors. New imino sugar glucosidase inhibitors are also disclosed, a class of compounds with potential for diabetes, Gaucher disease or cancer treatment. Also the development of a useful synthetic method towards multivalent glycoclusters of biomedical interest is here highlighted. The relevance of glycomimetics in drug discovery and the progress on carbohydrates in early diagnosis and cancer treatment are reviewed. Noteworthy is the chitosan-based delivery system for drug oral administration, a new biomaterial-based approach to improve bioavailability. Another study on the conformation of Streptococcus capsular polysaccharide backbones by molecular modelling provides useful information for bacterial immunotherapeutic approaches. All original contributions and reviews clearly demonstrate the potential of glycosciences for innovation in medicinal (glyco)chemistry and pharmaceutical research.

Legislative Proposals to Enhance Capital Formation ..., Serial No. 113-74, April 9, 2014, 113-2 Hrg

Author :
Publisher :
ISBN 13 :
Total Pages : 126 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Legislative Proposals to Enhance Capital Formation ..., Serial No. 113-74, April 9, 2014, 113-2 Hrg by :

Download or read book Legislative Proposals to Enhance Capital Formation ..., Serial No. 113-74, April 9, 2014, 113-2 Hrg written by and published by . This book was released on 2014 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Recent Advances in Endothelial Progenitor Cells Toward Their Use in Clinical Translation

Author : Reinhold J. Medina
Publisher : Frontiers Media SA
ISBN 13 : 2889634590
Total Pages : 107 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Recent Advances in Endothelial Progenitor Cells Toward Their Use in Clinical Translation by : Reinhold J. Medina

Download or read book Recent Advances in Endothelial Progenitor Cells Toward Their Use in Clinical Translation written by Reinhold J. Medina and published by Frontiers Media SA. This book was released on 2020-02-19 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since endothelial progenitor cells (EPCs) were first described in 1997, there has been significant debate surrounding their definition and roles; but also agreement in their potential to develop as biomarkers and cytotherapies. EPCs participate in vascular repair and postnatal angiogenesis by differentiating into endothelial cells or by producing pro–angiogenic growth factors. Various subtypes of EPCs have been studied, such as CD34+VEGFR2+ blood circulating cells, cultured endothelial colony forming cells (ECFCs), and myeloid angiogenic cells (MACs). EPCs have therapeutic potential for revascularisation and vascular repair in ischemic diseases such as myocardial infarction and diabetic vascular complications. In this eBook, we compile evidence to enable their translation including strategies to enhance the number, homing ability to the injury site and function of EPCs.

Handbook of Biochemistry and Molecular Biology

Author : Roger L. Lundblad
Publisher : CRC Press
ISBN 13 : 1315314436
Total Pages : 1001 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Handbook of Biochemistry and Molecular Biology by : Roger L. Lundblad

Download or read book Handbook of Biochemistry and Molecular Biology written by Roger L. Lundblad and published by CRC Press. This book was released on 2018-06-14 with total page 1001 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by renowned protein scientist and bestselling author Roger L. Lundblad, with the assistance of Fiona M. Macdonald of CRC Press, this fifth edition of the Handbook of Biochemistry and Molecular Biology gathers a wealth of information not easily obtained, including information not found on the web. Presented in an organized, concise, and simple-to-use format, this popular reference allows quick access to the most frequently used data. Covering a wide range of topics, from classical biochemistry to proteomics and genomics, it also details the properties of commonly used biochemicals, laboratory solvents, and reagents. An entirely new section on Chemical Biology and Drug Design gathers data on amino acid antagonists, click chemistry, plus glossaries for computational drug design and medicinal chemistry. Each table is exhaustively referenced, giving the user a quick entry point into the primary literature. New tables for this edition: Chromatographic methods and solvents Protein spectroscopy Partial volumes of amino acids Matrix Metalloproteinases Gene Editing Click Chemistry