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Glucocorticoid Inhibition Of Mammary Tumor Cell Growth And Transcriptional Regulation Of Sgk A Novel Protein Kinase
Download Glucocorticoid Inhibition Of Mammary Tumor Cell Growth And Transcriptional Regulation Of Sgk A Novel Protein Kinase full books in PDF, epub, and Kindle. Read online Glucocorticoid Inhibition Of Mammary Tumor Cell Growth And Transcriptional Regulation Of Sgk A Novel Protein Kinase ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author :Melanie Kathleen Webster Publisher :Ann Arbor, Mich. : University Microfilms International ISBN 13 : Total Pages :396 pages Book Rating :4.:/5 (33 download)
Book Synopsis Glucocorticoid Inhibition of Mammary Tumor Cell Growth and Transcriptional Regulation of SGK, a Novel Protein Kinase by : Melanie Kathleen Webster
Download or read book Glucocorticoid Inhibition of Mammary Tumor Cell Growth and Transcriptional Regulation of SGK, a Novel Protein Kinase written by Melanie Kathleen Webster and published by Ann Arbor, Mich. : University Microfilms International. This book was released on 1992 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cyclin Dependent Kinase 5 (Cdk5) by : Nancy Y. Ip
Download or read book Cyclin Dependent Kinase 5 (Cdk5) written by Nancy Y. Ip and published by Springer Science & Business Media. This book was released on 2009-02-28 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cyclin Dependent Kinase 5 provides a comprehensive and up-to-date collection of reviews on the discovery, signaling mechanisms and functions of Cdk5, as well as the potential implication of Cdk5 in the treatment of neurodegenerative diseases. Since the identification of this unique member of the Cdk family, Cdk5 has emerged as one of the most important signal transduction mediators in the development, maintenance and fine-tuning of neuronal functions and networking. Further studies have revealed that Cdk5 is also associated with the regulation of neuronal survival during both developmental stages and in neurodegenerative diseases. These observations indicate that precise control of Cdk5 is essential for the regulation of neuronal survival. The pivotal role Cdk5 appears to play in both the regulation of neuronal survival and synaptic functions thus raises the interesting possibility that Cdk5 inhibitors may serve as therapeutic treatment for a number of neurodegenerative diseases.
Book Synopsis Dissertation Abstracts International by :
Download or read book Dissertation Abstracts International written by and published by . This book was released on 1993 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Regulation of the Serum-and Glucocorticoid-inducible Protein Kinase, Sgk by Hormones and Cell Cycle by : Patricia Buse
Download or read book Regulation of the Serum-and Glucocorticoid-inducible Protein Kinase, Sgk by Hormones and Cell Cycle written by Patricia Buse and published by . This book was released on 1998 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Stress and Breast Cancer by : Cary L. Cooper
Download or read book Stress and Breast Cancer written by Cary L. Cooper and published by . This book was released on 1988 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years interest has increased in the links between stress and breast cancer, reflecting the growing concern at the continuing increase in the disease. This book brings together leading researchers in the field to review the evidence available.
Book Synopsis New Prognostic and Predictive Markers in Cancer Progression by : Susan Costantini Alfredo Budillon
Download or read book New Prognostic and Predictive Markers in Cancer Progression written by Susan Costantini Alfredo Budillon and published by MDPI. This book was released on 2021-02-12 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers are of critical medical importance for oncologists, allowing them to predict and detect disease and to determine the best course of action for cancer patient care. Prognostic markers are used to evaluate a patient’s outcome and cancer recurrence probability after initial interventions such as surgery or drug treatments and, hence, to select follow-up and further treatment strategies. On the other hand, predictive markers are increasingly being used to evaluate the probability of benefit from clinical intervention(s), driving personalized medicine. Evolving technologies and the increasing availability of “multiomics” data are leading to the selection of numerous potential biomarkers, based on DNA, RNA, miRNA, protein, and metabolic alterations within cancer cells or tumor microenvironment, that may be combined with clinical and pathological data to greatly improve the prediction of both cancer progression and therapeutic treatment responses. However, in recent years, few biomarkers have progressed from discovery to become validated tools to be used in clinical practice. This Special Issue comprises eight review articles and five original studies on novel potential prognostic and predictive markers for different cancer types.
Book Synopsis Protein Kinase Inhibitors by : Md. Imtaiyaz Hassan
Download or read book Protein Kinase Inhibitors written by Md. Imtaiyaz Hassan and published by Academic Press. This book was released on 2022-05-19 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Kinase Inhibitors: From Discovery to Therapeutics offers a foundational, pragmatic overview of protein kinases inhibitors and their potential role in disease modulation and treatment. Here, international experts in the field offer an integrated discussion of kinase inhibitor biology, biomarker discovery, and methods for drug design and development. After a brief overview of kinases and kinase inhibitors, subsequent chapters discuss individual kinases that are representative of the wider kinases and kinase families, including their roles in disease pathogenesis, underlying mechanisms, potential inhibitors and their modes of action for therapeutic modulation. Several potential drugs under different stages of clinical trials are discussed, including their relevance to cancer, diabetes, obesity, cardiovascular, neurological, and auto-immune and inflammatory disease, among other disorders. The book also addresses the challenges and opportunities for future kinase inhibitor development. - Provides a thorough overview of kinase inhibitor biology and its role in disease progression and modulation - Examines protein kinase inhibitor drugs in various stages of clinical trials and development - Offers methods and protocols for protein kinase inhibitor research studies and drug design and development - Includes chapter contributions from international leaders in the field
Book Synopsis Science In Medicine by : Ushma S. Neill
Download or read book Science In Medicine written by Ushma S. Neill and published by Jones & Bartlett Learning. This book was released on 2007-10-31 with total page 1180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science in Medicine: The JCI Textbook of Molecular Medicine is a collection of acclaimed articles published in the Journal of Clinical Investigation during the Journal’s tenure at Columbia University. The society that publishes the JCI, the American Society for Clinical Investigation (ASCI), is an honor society of physician scientists, representing those who are at the forefront of translating findings in the laboratory to the advancement of clinical practice. This textbook brings together state-of-the-art reviews written by the world's leading authorities, including many ASCI members. The reviews examine the molecular mechanisms underlying a wide array of diseases and disorders affecting all major organ systems. The fundamentals of the organ or physiological systems in question are present alongside the underlying genetic or physiological abnormalities that result in disease. This text illustrates the translation of basic scientific knowledge into the current practice of clinical medicine. The reviews provide an authoritative and comprehensive overview by building on known scientific concepts and treatment of human disease while exploring where these advances might take medicine over the next decade. The book is a valuable resource for medical students, graduate students, house staff, attending and practicing physicians, and biomedical researchers.
Book Synopsis Protein Kinases in Development and Disease by :
Download or read book Protein Kinases in Development and Disease written by and published by Academic Press. This book was released on 2017-02-22 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Kinases in Development and Disease discusses and reviews important, but often neglected, kinases. A good representation of current model organisms from plants and C. elegans to mice are used as the basis to illustrate how we can use our understanding of normal development to learn about disease. - Reviews kinases, the fundamental regulators of most biological processes that have key roles in the development of all organisms - Includes a broad scope of topics that are addressed - Allows researchers and newcomers to this research area to gain a thorough picture of the current knowledge
Book Synopsis PI3K signalling by : Klaus Okkenhaug
Download or read book PI3K signalling written by Klaus Okkenhaug and published by Frontiers Media SA. This book was released on 2015-03-05 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: The PI3Ks control many key functions in immune cells. PI3Ks phosphorylate PtdIns(4,5)P2 to yield PtdIns(3,4,5)P3. Initially, PI3K inhibitors such as Wortmannin, LY294002 and Rapamycin were used to establish a central role for Pi3K pathway in immune cells. Considerable progress in understanding the role of this pathway in cells of the immune system has been made in recent years, starting with analysis of various PI3K and Pten knockout mice and subsequently mTOR and Foxo knockout mice. Together, these experiments have revealed how PI3Ks control B cell and T cell development, T helper cell differentiation, regulatory T cell development and function, B cell and T cell trafficking, immunoglobulin class switching and much, much more. The PI3Kd inhibitor idelalisib has recently been approved for the treatment of B cell lymphoma. Clinical trials of other PI3K inhibitors in autoimmune and inflammatory diseases are also in progress. This is an opportune time to consider a Research Topic considering when what we have learned about the PI3K signalling module in lymphocyte biology and how this is making an impact on clinical immunology and haematology.
Book Synopsis Regulation of the Serum and Glucocorticoid Inducible Protein Kinase, Sgk, in Response to Multiple Stimuli and Its Role in Cell Survival Signaling by : Meredith Lai-Ling Leong
Download or read book Regulation of the Serum and Glucocorticoid Inducible Protein Kinase, Sgk, in Response to Multiple Stimuli and Its Role in Cell Survival Signaling written by Meredith Lai-Ling Leong and published by . This book was released on 2002 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2036 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1997 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Targeting New Pathways and Cell Death in Breast Cancer by : Rebecca Aft
Download or read book Targeting New Pathways and Cell Death in Breast Cancer written by Rebecca Aft and published by BoD – Books on Demand. This book was released on 2012-02-29 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents novel in interesting find by multiple accomplished investigators in breast cancer. These chapters elucidate new mechanisms of breast cancer cell death as well as discuss new pathways for therapeutic targeting.
Book Synopsis American Doctoral Dissertations by :
Download or read book American Doctoral Dissertations written by and published by . This book was released on 2002 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Inosine Monophosphate Dehydrogenase by : Krzysztof W. Pankiewicz
Download or read book Inosine Monophosphate Dehydrogenase written by Krzysztof W. Pankiewicz and published by . This book was released on 2003 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inosine Monophosphate Dehydrogenase, or IMPDH, is a critical enzyme in the regulation of cell proliferation and differentiation. A growing field of literature is addressing the characterization, mechanisms, and biological functions of IMPDH and its role as a target for both antileukemic and immunosuppressive therapy. This volume will provide and comprehensive look at the chemotherapeutic target IMPDH. In addition to an overview of the filed, this book will examine the molecular biology and genetics, the structure and mechanism of IMPDH, inhibitor design, clinical applications, and new trends in IMPDH for the future.
Download or read book Genetics Abstracts written by and published by . This book was released on 1999 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:
