Author : Fang He
Publisher : Frontiers Media SA
ISBN 13 : 2832530427
Total Pages : 154 pages
Book Rating : 4.8/5 (325 download)
Book Synopsis Global Dissemination and Evolution of Epidemic Multidrug-Resistant Gram-Negative Bacterial Pathogens: Surveillance, Diagnosis and Treatment Volume II by : Fang He
Download or read book Global Dissemination and Evolution of Epidemic Multidrug-Resistant Gram-Negative Bacterial Pathogens: Surveillance, Diagnosis and Treatment Volume II written by Fang He and published by Frontiers Media SA. This book was released on 2023-08-02 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: The inappropriate use of antibiotics and a lack of newly developed ones are the main contributors to the current antibiotic resistance crisis. The World Health Organization (WHO) has acknowledged that bacterial antibiotic resistance represents one of the biggest threats to global public health, increasing therapy costs and mortality rates in severe infections. The leading cause of nosocomial infections globally is primarily due to a league of gram-negative bacteria that readily develop antimicrobial resistance. They frequently cause severe disease and easily ‘escape’ the activity of antibiotics. However, many unanswered questions concerning the mechanisms of global dissemination and evolution patterns of these notorious epidemic multidrug-resistant gram-negative bacterial pathogens. Thus, the time is right now to arrange a Research Topic to present and highlight novel findings in this research field. This Research Topic highlights advances in understanding antimicrobial resistance mechanisms at the molecular level and the transmission dynamics and developing new treatments for multidrug-resistant gram-negative bacteria. This Research Topic welcomes genomic epidemiological studies to explore the molecular basis of antimicrobial resistance and to discover the new channels of resistance transmission between humans, animals, and the environment to encapsulate the ‘One Health’ concept. Also, surveillance on both global and local scales focuses on both the transmission of bacteria and the genes and mobile genetic elements (MGEs) that confer antimicrobial resistance to the ‘last-resort antimicrobial agents’ heightened virulence are more than welcome. Finally, studies that attempt to identify new resistance mechanisms, explore newly discovered antimicrobial agents, and introduce new techniques and methods for rapid detection, characterization, and elimination of multidrug-resistant gram-negative bacteria would be particularly welcome.