Author : Abu Saleh Mosa Faisal
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (134 download)
Book Synopsis GibbSeq2 by : Abu Saleh Mosa Faisal
Download or read book GibbSeq2 written by Abu Saleh Mosa Faisal and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of Gene Set Enrichment Analysis (GSEA) for high throughput sequencing data has gained a new dimension in the last decade. Several statistical methods and software tools have been developed for RNA-seq data to perform Differential Expression analysis. A new method ”gibbseq2” is proposed based on log-normal distribution and full Bayesian inference using Gibbs sampling to analyze RNA-seq data for detection of DE gene sets. This statistical method incorporated truncated log-normal distribution to detect the direction of DNA reads. It uses False Discovery Rate (FDR) and the power of the test to measure the performance of the algorithm. By using simulated data, we explored the method’s performance in controlling the type I error rate. This method performed equally or even better than other methods.
