Genomic Messages

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Genomic Messages

Author : George Annas
Publisher : HarperCollins
ISBN 13 : 0062228277
Total Pages : 245 pages
Book Rating : 4.0/5 (622 download)

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Book Synopsis Genomic Messages by : George Annas

Download or read book Genomic Messages written by George Annas and published by HarperCollins. This book was released on 2015-06-23 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two leaders in the field of genetics—a bioethicist-health lawyer and an obstetrician-gynecologist geneticist—answer the most pressing questions about the application of new genetics to our universal medicine and what personalized medicine means for individual healthcare. Breakthroughs in genetic research are changing modern medicine and pharmaceuticals. But what are these changes and how do they affect our individual care? Genomic Messages examines these groundbreaking changes and the questions they raise: What kind of specific medical innovation do we have to look forward to now and tomorrow? How will this “flood” of genetic messages change our lives, our interaction with our physicians and our healthcare system? Groundbreaking and provocative, Genomic Messages fuses the often conflicting worlds of medicine and law to provide information and insight that will impact the health choices of every one of us, from how medicine is practiced to concepts of privacy, confidentiality, and informed consent. Ultimately, it reveals how genetic information is changing how we think about ourselves, our health, and our future.

Bioinformatics in the Post-genomic Era

Author : Jeffrey Augen
Publisher : Addison-Wesley Professional
ISBN 13 :
Total Pages : 412 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Bioinformatics in the Post-genomic Era by : Jeffrey Augen

Download or read book Bioinformatics in the Post-genomic Era written by Jeffrey Augen and published by Addison-Wesley Professional. This book was released on 2005 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive treatment of the role of bioinformatics in the emerging world of molecular medicine, for anyone involved in this new field

Genomes and What to Make of Them

Author : Barry Barnes
Publisher : University of Chicago Press
ISBN 13 : 0226172961
Total Pages : 282 pages
Book Rating : 4.2/5 (261 download)

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Book Synopsis Genomes and What to Make of Them by : Barry Barnes

Download or read book Genomes and What to Make of Them written by Barry Barnes and published by University of Chicago Press. This book was released on 2009-05-15 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The announcement in 2003 that the Human Genome Project had completed its map of the entire human genome was heralded as a stunning scientific breakthrough: our first full picture of the basic building blocks of human life. Since then, boasts about the benefits—and warnings of the dangers—of genomics have remained front-page news, with everyone agreeing that genomics has the potential to radically alter life as we know it. For the nonscientist, the claims and counterclaims are dizzying—what does it really mean to understand the genome? Barry Barnes and John Dupré offer an answer to that question and much more in Genomes and What to Make of Them, a clear and lively account of the genomic revolution and its promise. The book opens with a brief history of the science of genetics and genomics, from Mendel to Watson and Crick and all the way up to Craig Venter; from there the authors delve into the use of genomics in determining evolutionary paths—and what it can tell us, for example, about how far we really have come from our ape ancestors. Barnes and Dupré then consider both the power and risks of genetics, from the economic potential of plant genomes to overblown claims that certain human genes can be directly tied to such traits as intelligence or homosexuality. Ultimately, the authors argue, we are now living with a new knowledge as powerful in its way as nuclear physics, and the stark choices that face us—between biological warfare and gene therapy, a new eugenics or a new agricultural revolution—will demand the full engagement of both scientists and citizens. Written in straightforward language but without denying the complexity of the issues, Genomes and What to Make of Them is both an up-to-date primer and a blueprint for the future.

Heritable Human Genome Editing

Author : The Royal Society
Publisher : National Academies Press
ISBN 13 : 0309671132
Total Pages : 239 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Heritable Human Genome Editing by : The Royal Society

Download or read book Heritable Human Genome Editing written by The Royal Society and published by National Academies Press. This book was released on 2021-01-16 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.

Information, The Hidden Side of Life

Author : Cédric Gaucherel
Publisher : John Wiley & Sons
ISBN 13 : 1119579325
Total Pages : 212 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Information, The Hidden Side of Life by : Cédric Gaucherel

Download or read book Information, The Hidden Side of Life written by Cédric Gaucherel and published by John Wiley & Sons. This book was released on 2019-01-03 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the unity of life. It proposes that the concept of information is the inner essence of what we today call life. The importance of information for our species is obvious. Human beings are highly dependent on information, constantly exchanging with conspecifics. In a less apparent way, we are the product of genetic and epigenetic information which determines our development in a given environment from a fertilized egg to the adult stage. Even less apparent is that information plays a determining role in ecosystems. This observation may include the prebiotic systems in which life emerged. Our claim is that Nature processes information continuously. This means that even beyond living entities, we can see messages and decoding procedures. Nature can be said to send messages to its own future and then to decode them. Nature “talks” to itself! The systematic organization of messages suggests that, in some respects, we should even speak of the “languages” of Nature.

An Outline of Informational Genetics

Author : Gerard Battail
Publisher : Springer Nature
ISBN 13 : 3031016297
Total Pages : 191 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis An Outline of Informational Genetics by : Gerard Battail

Download or read book An Outline of Informational Genetics written by Gerard Battail and published by Springer Nature. This book was released on 2022-06-01 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heredity performs literal communication of immensely long genomes through immensely long time intervals. Genomes nevertheless incur sporadic errors referred to as mutations which have significant and often dramatic effects, after a time interval as short as a human life. How can faithfulness at a very large timescale and unfaithfulness at a very short one be conciliated? The engineering problem of literal communication has been completely solved during the second half of the XX-th century. Originating in 1948 from Claude Shannon's seminal work, information theory provided means to measure information quantities and proved that communication is possible through an unreliable channel (by means left unspecified) up to a sharp limit referred to as its capacity, beyond which communication becomes impossible. The quest for engineering means of reliable communication, named error-correcting codes, did not succeed in closely approaching capacity until 1993 when Claude Berrou and Alain Glavieux invented turbocodes. By now, the electronic devices which invaded our daily lives (e.g., CD, DVD, mobile phone, digital television) could not work without highly efficient error-correcting codes. Reliable communication through unreliable channels up to the limit of what is theoretically possible has become a practical reality: an outstanding achievement, however little publicized. As an engineering problem that nature solved aeons ago, heredity is relevant to information theory. The capacity of DNA is easily shown to vanish exponentially fast, which entails that error-correcting codes must be used to regenerate genomes so as to faithfully transmit the hereditary message. Moreover, assuming that such codes exist explains basic and conspicuous features of the living world, e.g., the existence of discrete species and their hierarchical taxonomy, the necessity of successive generations and even the trend of evolution towards increasingly complex beings. Providing geneticists with an introduction to information theory and error-correcting codes as necessary tools of hereditary communication is the primary goal of this book. Some biological consequences of their use are also discussed, and guesses about hypothesized genomic codes are presented. Another goal is prompting communication engineers to get interested in genetics and biology, thereby broadening their horizon far beyond the technological field, and learning from the most outstanding engineer: Nature. Table of Contents: Foreword / Introduction / A Brief Overview of Molecular Genetics / An Overview of Information Theory / More on Molecular Genetics / More on Information Theory / An Outline of Error-Correcting Codes / DNA is an Ephemeral Memory / A Toy Living World / Subsidiary Hypothesis, Nested System / Soft Codes / Biological Reality Conforms to the Hypotheses / Identification of Genomic Codes / Conclusion and Perspectives

Introduction to Genomics

Author : Arthur Lesk
Publisher : Oxford University Press, USA
ISBN 13 : 0199564353
Total Pages : 421 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis Introduction to Genomics by : Arthur Lesk

Download or read book Introduction to Genomics written by Arthur Lesk and published by Oxford University Press, USA. This book was released on 2012 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest techniques that enable us to study the genome in detail, the book explores what the genome tells us about life at the level of the molecule, the cell, and the organism

The Genome Defense

Author : Jorge L. Contreras
Publisher : Algonquin Books
ISBN 13 : 1616209682
Total Pages : 433 pages
Book Rating : 4.6/5 (162 download)

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Book Synopsis The Genome Defense by : Jorge L. Contreras

Download or read book The Genome Defense written by Jorge L. Contreras and published by Algonquin Books. This book was released on 2021-10-26 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The gripping true story of a Supreme Court civil rights battle to prevent biotech companies from owning the very thing that makes us who we are-our DNA"--

Oncogenes in B-Cell Neoplasia

Author : M. Potter
Publisher : Springer Science & Business Media
ISBN 13 : 3642698603
Total Pages : 281 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Oncogenes in B-Cell Neoplasia by : M. Potter

Download or read book Oncogenes in B-Cell Neoplasia written by M. Potter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genomic Citizenship

Author : Ian McGonigle
Publisher : MIT Press
ISBN 13 : 0262542943
Total Pages : 221 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Genomic Citizenship by : Ian McGonigle

Download or read book Genomic Citizenship written by Ian McGonigle and published by MIT Press. This book was released on 2021-08-24 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: An anthropological study based on ethnographic work in Israel and Qatar explores the relationship between science, particularly genetics, and national identity. Based on ethnographic work in Israel and Qatar, two small Middle Eastern ethnonations with significant biomedical resources, Genomic Citizenship explores the relationship between science and identity. Ian McGonigle, originally trained as a biochemist, draws on anthropological theory, STS, intellectual history, critical theory, Middle Eastern studies, cultural studies, and critical legal studies. He connects biomedical research on ethnic populations to the political, economic, legal, and historical context of the state; to global trends in genetic medicine; and to the politics of identity in the context of global biomedical research. Genomic Citizenship is more an anthropology of scientific objects than an anthropology of scientists or an ethnography of the laboratory. McGonigle bases his untraditional project on traditional anthropological methods, including participant observation. Some of the most persuasive data in the book are from public records, legal and historical sources, published scientific papers, institutional reports, websites, and brochures. McGonigle discusses biological understandings of Jewishness, especially in relation to the intellectual history of Zionism and Jewish political thought, and considers the possibility of a novel application of genetics in assigning Israeli citizenship. He also describes developments in genetic medicine in Qatar and analyzes the Qatari Biobank in the context of Qatari nationalism and state-building projects. Considering possible consequences of findings on the diverse origins of the Qatari population for tribal identities, he argues that the nation cannot be defined as either a purely natural or biological entity. Rather, it is reified, reinscribed, and refracted through genomic research and discourse.

Genomic and Personalized Medicine

Author :
Publisher : Academic Press
ISBN 13 : 0123822289
Total Pages : 1350 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Genomic and Personalized Medicine by :

Download or read book Genomic and Personalized Medicine written by and published by Academic Press. This book was released on 2012-10-30 with total page 1350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic and Personalized Medicine, Second Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — is a major discussion of the structure, history, and applications of the field, as it emerges from the campus and lab into clinical action. As with the first edition, leading experts review the development of the new science, the current opportunities for genome-based analysis in healthcare, and the potential of genomic medicine in future healthcare. The inclusion of the latest information on diagnostic testing, population screening, disease susceptability, and pharmacogenomics makes this work an ideal companion for the many stakeholders of genomic and personalized medicine. With advancing knowledge of the genome across and outside protein-coding regions of DNA, new comprehension of genomic variation and frequencies across populations, the elucidation of advanced strategic approaches to genomic study, and above all in the elaboration of next-generation sequencing, genomic medicine has begun to achieve the much-vaunted transformative health outcomes of the Human Genome Project, almost a decade after its official completion in April 2003. Highly Commended 2013 BMA Medical Book Award for Medicine More than 100 chapters, from leading researchers, review the many impacts of genomic discoveries in clinical action, including 63 chapters new to this edition Discusses state-of-the-art genome technologies, including population screening, novel diagnostics, and gene-based therapeutics Wide and inclusive discussion encompasses the formidable ethical, legal, regulatory and social challenges related to the evolving practice of genomic medicine Clearly and beautifully illustrated with 280 color figures, and many thousands of references for further reading and deeper analysis

Genome

Author : Matt Ridley
Publisher : Harper Collins
ISBN 13 : 0062253468
Total Pages : 370 pages
Book Rating : 4.0/5 (622 download)

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Book Synopsis Genome by : Matt Ridley

Download or read book Genome written by Matt Ridley and published by Harper Collins. This book was released on 2013-03-26 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Ridley leaps from chromosome to chromosome in a handy summation of our ever increasing understanding of the roles that genes play in disease, behavior, sexual differences, and even intelligence. . . . . He addresses not only the ethical quandaries faced by contemporary scientists but the reductionist danger in equating inheritability with inevitability.” — The New Yorker The genome's been mapped. But what does it mean? Matt Ridley’s Genome is the book that explains it all: what it is, how it works, and what it portends for the future Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.

Genetic Counseling

Author : Dianne M. Bartels
Publisher : Routledge
ISBN 13 : 1351517953
Total Pages : 206 pages
Book Rating : 4.3/5 (515 download)

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Book Synopsis Genetic Counseling by : Dianne M. Bartels

Download or read book Genetic Counseling written by Dianne M. Bartels and published by Routledge. This book was released on 2017-07-12 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic counseling is fairly new. The fact that the field is an accepted professional enterprise in universities, clinics, and hospitals throughout the United States is remarkable. The contributors argue that genetics and medicine rest on beliefs widely held in American society. Scientific progress is good, and highly sophisticated technologies are appropriate means to solving medical problems. The better understanding they gain about the nature and evolution of disease, the more prepared clinicians will be to treat and prevent future occurrence of disease. A belief that medicine, including genetic medicine, is clear, factually based, and objective undergirds the strategies and norms of genetic counseling. This collection of original papers explores the history, values, and norms of that process, with focus on the value of non-directiveness in counseling practice. The contributors' examination of genetic counseling issues serves as a foundation from which to address the ethical, legal, and policy considerations of clinical genetics.

Multiple Testing Procedures with Applications to Genomics

Author : Sandrine Dudoit
Publisher : Springer Science & Business Media
ISBN 13 : 0387493174
Total Pages : 611 pages
Book Rating : 4.3/5 (874 download)

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Book Synopsis Multiple Testing Procedures with Applications to Genomics by : Sandrine Dudoit

Download or read book Multiple Testing Procedures with Applications to Genomics written by Sandrine Dudoit and published by Springer Science & Business Media. This book was released on 2007-12-18 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. These are applied to a range of problems in biomedical and genomic research, including identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments; tests of association between gene expression measures and biological annotation metadata; sequence analysis; and genetic mapping of complex traits using single nucleotide polymorphisms. The procedures are based on a test statistics joint null distribution and provide Type I error control in testing problems involving general data generating distributions, null hypotheses, and test statistics.

Genomic Politics

Author : Jennifer Hochschild
Publisher : Oxford University Press
ISBN 13 : 0197550738
Total Pages : 337 pages
Book Rating : 4.1/5 (975 download)

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Book Synopsis Genomic Politics by : Jennifer Hochschild

Download or read book Genomic Politics written by Jennifer Hochschild and published by Oxford University Press. This book was released on 2021 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: A groundbreaking analysis of how the genomic revolution is transforming American society and creating new social divisions - some along racial lines - that promise to fundamentally shape American politics for years to come.The emergence of genomic science in the last quarter century has revolutionized medicine, the justice system, and our very understanding of who we are. We use genomics to determine guilt and exonerate the convicted; devise new medicines; test embryos; and discover our ethnic and national roots. Onemight think that, given these advances, most would favor the availability of genomic tools. Yet as Jennifer Hochschild explains in Genomic Politics , the uses of genomic science are both politically charged and hotly contested.The political divisions around genomics do not follow the usual left-right ideological divides that dominate most of American politics. Through four controversial innovations resulting from genomic science - genetically modified medicines that target African-Americans, who are demographically moresusceptible to heart disease; the use of DNA evidence in the criminal justice system; the current ancestry craze; and the use of genetic tests in prenatal exams - Hochschild reveals how the phenomenon is polarizing America in novel ways. Advocates of genomic science argue that these applicationswill make life better, but their opponents respond by pointing out the potential for misuse - from racial profiling to "selecting out" fetuses that gene tests show to have conditions like Down's Syndrome. Hochschild's central message is that the divide hinges on answers to two questions: Howsignificant are genetic factors in explaining human traits and behaviors? And what is the right balance between risk acceptance and risk avoidance for a society grappling with innovations arising from genomic science? A deeply researched and original analysis of the politics surrounding one of thesignal issues of our times, this is essential reading for anyone interested in how the genetics revolution is reshaping society.

The Genome Factor

Author : Dalton Conley
Publisher : Princeton University Press
ISBN 13 : 0691183163
Total Pages : 294 pages
Book Rating : 4.6/5 (911 download)

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Book Synopsis The Genome Factor by : Dalton Conley

Download or read book The Genome Factor written by Dalton Conley and published by Princeton University Press. This book was released on 2018-11-13 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: "For a century, social scientists have avoided genetics like the plague. But in the past decade, a small but intrepid group of economists, political scientists, and sociologists have harnessed the genomics revolution to paint a more complete picture of human social life than ever before. The Genome Factor describes the latest astonishing discoveries being made at the scientific frontier where genomics and the social sciences intersect. The Genome Factor reveals that there are real genetic differences by racial ancestry--but ones that don't conform to what we call black, white, or Latino. Genes explain a significant share of who gets ahead in society and who does not, but instead of giving rise to a genotocracy, genes often act as engines of mobility that counter social disadvantage. An increasing number of us are marrying partners with similar education levels as ourselves, but genetically speaking, humans are mixing it up more than ever before with respect to mating and reproduction. These are just a few of the many findings presented in this illuminating and entertaining book, which also tackles controversial topics such as genetically personalized education and the future of reproduction in a world where more and more of us are taking advantage of cheap genotyping services like 23andMe to find out what our genes may hold in store for ourselves and our children. The Genome Factor shows how genomics is transforming the social sciences--and how social scientists are integrating both nature and nurture into a unified, comprehensive understanding of human behavior at both the individual and society-wide levels."--

The Importance of Diversity in Precision Medicine Research

Author : Dana C. Crawford
Publisher : Frontiers Media SA
ISBN 13 : 2889660990
Total Pages : 98 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis The Importance of Diversity in Precision Medicine Research by : Dana C. Crawford

Download or read book The Importance of Diversity in Precision Medicine Research written by Dana C. Crawford and published by Frontiers Media SA. This book was released on 2020-10-30 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.