Genomes

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Genome

Author : Matt Ridley
Publisher : Harper Collins
ISBN 13 : 0062253468
Total Pages : 370 pages
Book Rating : 4.0/5 (622 download)

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Book Synopsis Genome by : Matt Ridley

Download or read book Genome written by Matt Ridley and published by Harper Collins. This book was released on 2013-03-26 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Ridley leaps from chromosome to chromosome in a handy summation of our ever increasing understanding of the roles that genes play in disease, behavior, sexual differences, and even intelligence. . . . . He addresses not only the ethical quandaries faced by contemporary scientists but the reductionist danger in equating inheritability with inevitability.” — The New Yorker The genome's been mapped. But what does it mean? Matt Ridley’s Genome is the book that explains it all: what it is, how it works, and what it portends for the future Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.

Mapping and Sequencing the Human Genome

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309038405
Total Pages : 128 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Mapping and Sequencing the Human Genome by : National Research Council

Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Genomes

Author : Terence A. Brown
Publisher :
ISBN 13 :
Total Pages : 608 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genomes by : Terence A. Brown

Download or read book Genomes written by Terence A. Brown and published by . This book was released on 2002 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomes 2 covers modern molecular genetics from the genomics perspective, incorporating major advances made in the past three years, including the sequencing of the human genome, characterization of genome expression and replication processes, and transcriptomics and proteomics. The text is richly illustrated with clear, easy-to-follow, full-color diagrams, which are downloadable from the book's website.

Genomes and What to Make of Them

Author : Barry Barnes
Publisher : University of Chicago Press
ISBN 13 : 0226172961
Total Pages : 282 pages
Book Rating : 4.2/5 (261 download)

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Book Synopsis Genomes and What to Make of Them by : Barry Barnes

Download or read book Genomes and What to Make of Them written by Barry Barnes and published by University of Chicago Press. This book was released on 2009-05-15 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The announcement in 2003 that the Human Genome Project had completed its map of the entire human genome was heralded as a stunning scientific breakthrough: our first full picture of the basic building blocks of human life. Since then, boasts about the benefits—and warnings of the dangers—of genomics have remained front-page news, with everyone agreeing that genomics has the potential to radically alter life as we know it. For the nonscientist, the claims and counterclaims are dizzying—what does it really mean to understand the genome? Barry Barnes and John Dupré offer an answer to that question and much more in Genomes and What to Make of Them, a clear and lively account of the genomic revolution and its promise. The book opens with a brief history of the science of genetics and genomics, from Mendel to Watson and Crick and all the way up to Craig Venter; from there the authors delve into the use of genomics in determining evolutionary paths—and what it can tell us, for example, about how far we really have come from our ape ancestors. Barnes and Dupré then consider both the power and risks of genetics, from the economic potential of plant genomes to overblown claims that certain human genes can be directly tied to such traits as intelligence or homosexuality. Ultimately, the authors argue, we are now living with a new knowledge as powerful in its way as nuclear physics, and the stark choices that face us—between biological warfare and gene therapy, a new eugenics or a new agricultural revolution—will demand the full engagement of both scientists and citizens. Written in straightforward language but without denying the complexity of the issues, Genomes and What to Make of Them is both an up-to-date primer and a blueprint for the future.

Ecological Genomics

Author : Christian R. Landry
Publisher : Springer Science & Business Media
ISBN 13 : 9400773471
Total Pages : 358 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Ecological Genomics by : Christian R. Landry

Download or read book Ecological Genomics written by Christian R. Landry and published by Springer Science & Business Media. This book was released on 2013-11-25 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers in the field of ecological genomics aim to determine how a genome or a population of genomes interacts with its environment across ecological and evolutionary timescales. Ecological genomics is trans-disciplinary by nature. Ecologists have turned to genomics to be able to elucidate the mechanistic bases of the biodiversity their research tries to understand. Genomicists have turned to ecology in order to better explain the functional cellular and molecular variation they observed in their model organisms. We provide an advanced-level book that covers this recent research and proposes future development for this field. A synthesis of the field of ecological genomics emerges from this volume. Ecological Genomics covers a wide array of organisms (microbes, plants and animals) in order to be able to identify central concepts that motivate and derive from recent investigations in different branches of the tree of life. Ecological Genomics covers 3 fields of research that have most benefited from the recent technological and conceptual developments in the field of ecological genomics: the study of life-history evolution and its impact of genome architectures; the study of the genomic bases of phenotypic plasticity and the study of the genomic bases of adaptation and speciation.

The $1,000 Genome

Author : Kevin Davies
Publisher : Simon and Schuster
ISBN 13 : 1416569618
Total Pages : 352 pages
Book Rating : 4.4/5 (165 download)

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Book Synopsis The $1,000 Genome by : Kevin Davies

Download or read book The $1,000 Genome written by Kevin Davies and published by Simon and Schuster. This book was released on 2015-08-18 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2000, President Bill Clinton signaled the completion of the Human Genome Project at a cost in excess of $2 billion. A decade later, the price for any of us to order our own personal genome sequence--a comprehensive map of the 3 billion letters in our DNA--is rapidly and inevitably dropping to just $1,000. Dozens of men and women--scientists, entrepreneurs, celebrities, and patients--have already been sequenced, pioneers in a bold new era of personalized genomic medicine. The $1,000 genome has long been considered the tipping point that would open the floodgates to this revolution. Do you have gene variants associated with Alzheimer's or diabetes, heart disease or cancer? Which drugs should you consider taking for various diseases, and at what dosage? In the years to come, doctors will likely be able to tackle all of these questions--and many more--by using a computer in their offices to call up your unique genome sequence, which will become as much a part of your medical record as your blood pressure.

Human Genes and Genomes

Author : Leon E. Rosenberg
Publisher : Academic Press
ISBN 13 : 0123852137
Total Pages : 446 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Human Genes and Genomes by : Leon E. Rosenberg

Download or read book Human Genes and Genomes written by Leon E. Rosenberg and published by Academic Press. This book was released on 2012-05-21 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the nearly 60 years since Watson and Crick proposed the double helical structure of DNA, the molecule of heredity, waves of discoveries have made genetics the most thrilling field in the sciences. The study of genes and genomics today explores all aspects of the life with relevance in the lab, in the doctor’s office, in the courtroom and even in social relationships. In this helpful guidebook, one of the most respected and accomplished human geneticists of our time communicates the importance of genes and genomics studies in all aspects of life. With the use of core concepts and the integration of extensive references, this book provides students and professionals alike with the most in-depth view of the current state of the science and its relevance across disciplines. Bridges the gap between basic human genetic understanding and one of the most promising avenues for advances in the diagnosis, prevention and treatment of human disease. Includes the latest information on diagnostic testing, population screening, predicting disease susceptibility, pharmacogenomics and more Explores ethical, legal, regulatory and economic aspects of genomics in medicine. Integrates historical (classical) genetics approach with the latest discoveries in structural and functional genomics

From Genes to Genomes

Author : Jeremy W. Dale
Publisher : Wiley
ISBN 13 : 9780471497820
Total Pages : 372 pages
Book Rating : 4.4/5 (978 download)

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Book Synopsis From Genes to Genomes by : Jeremy W. Dale

Download or read book From Genes to Genomes written by Jeremy W. Dale and published by Wiley. This book was released on 2002-10-08 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid advances in our understanding of genetics have required that new books contain topics such as the concept and theory of gene cloning, transgenics, genomics, and various other coverage of traditional and contemporary subjects. Although there is an abundance of textbooks that cover introductory genetics and advanced courses in genetics, there is a noticeable gap at the intermediate (second year) level. In the past gene structure, function and expression were taught at final year /postgraduate level, but the rapid advances in our understanding of genetics has encouraged courses to change considerably. Over recent years these topics have filtered down the curriculum and are currently taught as core topics at second year, with a corresponding change in textbook requirements. Where once second year students were restricted to learning about the concept and theory of gene cloning, now they routinely clone genes for themselves as part of their practical assignments. Genes to Genomics will fill the gap, cover much of the same ground as previous titles, but go further on contemporary topics like transgenics, sequence comparison and analysis of variation. * A concise, up to date textbook that provides a balanced coverage of traditional and contemporary topics taught within intermediate courses in molecular genetics * Jeremy Dale has a proven track record as the successful author of Molecular Genetics of Bacteria * Genes to Genomics will include a series of feature box-outs that will examine some of the topical issues related to the scientific concepts and examples explored within the text * A range of questions and exercises including worked examples and web-based practicals * An accompanying web site will allow the authors to keep their audience up to date in the areas that are prone to date most rapidly between successive editions of the textbook. It will also include the illustrations and images from the textbook, in addition to worked examples, answers to questions within the book, and links to related websites of key interest.

Evolution of the Human Genome II

Author : Naruya Saitou
Publisher : Springer Nature
ISBN 13 : 4431569049
Total Pages : 260 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Evolution of the Human Genome II by : Naruya Saitou

Download or read book Evolution of the Human Genome II written by Naruya Saitou and published by Springer Nature. This book was released on 2021-05-27 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume set provides a general overview of the evolution of the human genome; The first volume overviews the human genome with descriptions of important gene groups. This second volume provides up-to-date, concise yet ample knowledge on the genome evolution of modern humans. It comprises twelve chapters divided into two parts discussing “Non-neutral Evolution on Human Genes” (Part I) and “Evolution of Modern Human Populations” (Part II.) The most significant feature of this book is the continent-wise discussion of modern human dispersal using human genomic data in Part II. Recent results such as introgression of paleogenomes to modern humans, new methods such as computer simulation of global human dispersals, and new information on genes for humanness will be of particular interest to the readers. Since the euchromatin regions of the human genome was sequenced in 2003, a huge number of research papers were published on modern human evolution for a variety of populations. It is now time to summarize these achievements. This book stands out as the most comprehensive book on the modern human evolution, focusing on genomic points of view with a broad scope. Primary target audiences are researchers and graduate students in evolutionary biology.

The Book of Genes & Genomes

Author : Huntington Willard
Publisher : Springer
ISBN 13 : 9780387709154
Total Pages : 400 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis The Book of Genes & Genomes by : Huntington Willard

Download or read book The Book of Genes & Genomes written by Huntington Willard and published by Springer. This book was released on 2017-01-08 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Book of Genes & Genomes presents a concise overview of the advances in genetics and genomics and provide the unfamiliar reader with a succinct description of many of the applications and implications of this field. Given the substantial investment in genetics and genomics over the past several decades and the many recent discoveries and developments, this book will help the reader begin to understand the importance of genetics and genomics to us all. This exciting new title includes information on how genetics and genomics has advanced our understanding of health and medicine, evolution, and biology, as well as how they are pushing the boundaries of ethics and social values.

Curiosity Guides: The Human Genome

Author : John Quackenbush
Publisher : Charlesbridge
ISBN 13 : 1607343568
Total Pages : 189 pages
Book Rating : 4.6/5 (73 download)

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Book Synopsis Curiosity Guides: The Human Genome by : John Quackenbush

Download or read book Curiosity Guides: The Human Genome written by John Quackenbush and published by Charlesbridge. This book was released on 2011-02-01 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: The DNA sequence that comprises the human genome--the genetic blueprint found in each of our cells--is undoubtedly the greatest code ever to be broken. Completed at the dawn of a new millennium, the feat electrified both the scientific community and the general public with its tantalizing promise of new and better treatments for countless diseases, including Alzheimer's, cancer, diabetes, and Parkinson's. Yet what is arguably the most important discovery of our time has also opened a Pandora's box of questions about who we are as humans and how the unique information stored in our genomes can and might be used, making it all the more important for everyone to understand the new science of genomics. In the CURIOSITY GUIDE TO THE HUMAN GENOME, Dr. John Quackenbush, a renowned scientist and professor, conducts a fascinating tour of the history and science behind the Human Genome Project and the technologies that are revolutionizing the practice of medicine today. With a clear and engaging narrative style, he demystifies the fundamental principles of genetics and molecular biology, including the astounding ways in which genes function, alone or together with other genes and the environment, to either sustain life or trigger disease. In addition, Dr. Quackenbush goes beyond medicine to examine how DNA-sequencing technology is changing how we think of ourselves as a species by providing new insights about our earliest ancestors and reconfirming our inextricable link to all life on earth. Finally, he explores the legal and ethical questions surrounding such controversial topics as stem cell research, prenatal testing, forensics, and cloning, making this volume of the Curiosity Guides series an indispensable resource for navigating our brave new genomic world.

Plant Genes, Genomes and Genetics

Author : Erich Grotewold
Publisher : John Wiley & Sons
ISBN 13 : 1119998883
Total Pages : 261 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Plant Genes, Genomes and Genetics by : Erich Grotewold

Download or read book Plant Genes, Genomes and Genetics written by Erich Grotewold and published by John Wiley & Sons. This book was released on 2015-06-02 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Genes, Genomes and Genetics provides a comprehensive treatment of all aspects of plant gene expression. Unique in explaining the subject from a plant perspective, it highlights the importance of key processes, many first discovered in plants, that impact how plants develop and interact with the environment. This text covers topics ranging from plant genome structure and the key control points in how genes are expressed, to the mechanisms by which proteins are generated and how their activities are controlled and altered by posttranslational modifications. Written by a highly respected team of specialists in plant biology with extensive experience in teaching at undergraduate and graduate level, this textbook will be invaluable for students and instructors alike. Plant Genes, Genomes and Genetics also includes: specific examples that highlight when and how plants operate differently from other organisms special sections that provide in-depth discussions of particular issues end-of-chapter problems to help students recapitulate the main concepts rich, full-colour illustrations and diagrams clearly showing important processes in plant gene expression a companion website with PowerPoint slides, downloadable figures, and answers to the questions posed in the book Aimed at upper level undergraduates and graduate students in plant biology, this text is equally suited for advanced agronomy and crop science students inclined to understand molecular aspects of organismal phenomena. It is also an invaluable starting point for professionals entering the field of plant biology.

Genes And Genomes

Author : Maxine Singer
Publisher : University Science Books
ISBN 13 : 9780935702170
Total Pages : 964 pages
Book Rating : 4.7/5 (21 download)

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Book Synopsis Genes And Genomes by : Maxine Singer

Download or read book Genes And Genomes written by Maxine Singer and published by University Science Books. This book was released on 1991 with total page 964 pages. Available in PDF, EPUB and Kindle. Book excerpt: The celebrated authors present an in-depth overview of the molecular structures and mechanisms that underlie the utilization of genetic information by complex organisms. They emphasize the experimental aspects of molecular genetics, offering a complete introduction to both principles and methods. "Excellent, suitably detailed and superbly written." Philip Leder, Harvard Medical School

Neanderthal Man

Author : Svante Pbo
Publisher : Basic Books (AZ)
ISBN 13 : 0465020836
Total Pages : 290 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis Neanderthal Man by : Svante Pbo

Download or read book Neanderthal Man written by Svante Pbo and published by Basic Books (AZ). This book was released on 2014-02-11 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: An influential geneticist traces his investigation into the genes of humanity's closest evolutionary relatives, explaining what his sequencing of the Neanderthal genome has revealed about their extinction and the origins of modern humans.

The Genome Odyssey

Author : Dr. Euan Angus Ashley
Publisher : Celadon Books
ISBN 13 : 1250234972
Total Pages : 221 pages
Book Rating : 4.2/5 (52 download)

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Book Synopsis The Genome Odyssey by : Dr. Euan Angus Ashley

Download or read book The Genome Odyssey written by Dr. Euan Angus Ashley and published by Celadon Books. This book was released on 2021-02-23 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease. Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human. In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome. These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.

The Barley Genome

Author : Nils Stein
Publisher : Springer
ISBN 13 : 3319925288
Total Pages : 394 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis The Barley Genome by : Nils Stein

Download or read book The Barley Genome written by Nils Stein and published by Springer. This book was released on 2018-08-18 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of the state-of-the-art in barley genome analysis, covering all aspects of sequencing the genome and translating this important information into new knowledge in basic and applied crop plant biology and new tools for research and crop improvement. Unlimited access to a high-quality reference sequence is removing one of the major constraints in basic and applied research. This book summarizes the advanced knowledge of the composition of the barley genome, its genes and the much larger non-coding part of the genome, and how this information facilitates studying the specific characteristics of barley. One of the oldest domesticated crops, barley is the small grain cereal species that is best adapted to the highest altitudes and latitudes, and it exhibits the greatest tolerance to most abiotic stresses. With comprehensive access to the genome sequence, barley’s importance as a genetic model in comparative studies on crop species like wheat, rye, oats and even rice is likely to increase.

Genomic Signal Processing and Statistics

Author : Edward R. Dougherty
Publisher : Hindawi Publishing Corporation
ISBN 13 : 9775945070
Total Pages : 456 pages
Book Rating : 4.7/5 (759 download)

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Book Synopsis Genomic Signal Processing and Statistics by : Edward R. Dougherty

Download or read book Genomic Signal Processing and Statistics written by Edward R. Dougherty and published by Hindawi Publishing Corporation. This book was released on 2005 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in genomic studies have stimulated synergetic research and development in many cross-disciplinary areas. Processing the vast genomic data, especially the recent large-scale microarray gene expression data, to reveal the complex biological functionality, represents enormous challenges to signal processing and statistics. This perspective naturally leads to a new field, genomic signal processing (GSP), which studies the processing of genomic signals by integrating the theory of signal processing and statistics. Written by an international, interdisciplinary team of authors, this invaluable edited volume is accessible to students just entering this emergent field, and to researchers, both in academia and in industry, in the fields of molecular biology, engineering, statistics, and signal processing. The book provides tutorial-level overviews and addresses the specific needs of genomic signal processing students and researchers as a reference book. The book aims to address current genomic challenges by exploiting potential synergies between genomics, signal processing, and statistics, with special emphasis on signal processing and statistical tools for structural and functional understanding of genomic data. The first part of this book provides a brief history of genomic research and a background introduction from both biological and signal-processing/statistical perspectives, so that readers can easily follow the material presented in the rest of the book. In what follows, overviews of state-of-the-art techniques are provided. We start with a chapter on sequence analysis, and follow with chapters on feature selection, classification, and clustering of microarray data. We then discuss the modeling, analysis, and simulation of biological regulatory networks, especially gene regulatory networks based on Boolean and Bayesian approaches. Visualization and compression of gene data, and supercomputer implementation of genomic signal processing systems are also treated. Finally, we discuss systems biology and medical applications of genomic research as well as the future trends in genomic signal processing and statistics research.