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Genetics For Rheumatologists
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Book Synopsis Genetics for Rheumatologists by : Matthew A. Brown
Download or read book Genetics for Rheumatologists written by Matthew A. Brown and published by Remedica. This book was released on 2002 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation Trainee and practicing rheumatologists The study of disease genetics arguably began in rheumatology, with the description of the hereditary basis of alkaptonuria by Garrod in 1902, and the introduction of the concept of in-born errors of metabolism. A large proportion of the diseases seen by rheumatologists have genetic influences. The dissection of the genetic basis of rheumatic diseases has moved rapidly over the past 15 years. Increasingly, rheumatologists are being asked the question "How likely is it that my children will develop the disease I have?', and about the utility of genetic testing for those diseases. This book is not a hefty tome full of genetics jargon, but a quick reference source for doctors written to help answer those questions.
Book Synopsis The Hereditary Basis of Rheumatic Diseases by : Rikard Holmdahl
Download or read book The Hereditary Basis of Rheumatic Diseases written by Rikard Holmdahl and published by Springer Science & Business Media. This book was released on 2006-07-02 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rheumatoid Arthritis (RA) represents a complex disease where the inheritable component has been estimated to be up to 60%. This PIR volume deals with the genetic basis and regulation of rheumatic diseases. The first part of the book describes genetic studies on rheumatic diseases. The second part deals with the shared heredity of rheumatic diseases, e.g., RA, lupus and ankylosing spondylitis. The third part of the volume describes tools for analysing genetic complexity, ranging from animal models to new molecular tools. The volume is essential reading for researchers and clinicians from rheumatology, inflammation research, immunology, and cell and molecular biology.
Book Synopsis The Hereditary Basis of Rheumatic Diseases by : Rikard Holmdahl
Download or read book The Hereditary Basis of Rheumatic Diseases written by Rikard Holmdahl and published by Birkhäuser. This book was released on 2009-09-03 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rheumatoid Arthritis (RA) represents a complex disease where the inheritable component has been estimated to be up to 60%. This PIR volume deals with the genetic basis and regulation of rheumatic diseases. The first part of the book describes genetic studies on rheumatic diseases. The second part deals with the shared heredity of rheumatic diseases, e.g., RA, lupus and ankylosing spondylitis. The third part of the volume describes tools for analysing genetic complexity, ranging from animal models to new molecular tools. The volume is essential reading for researchers and clinicians from rheumatology, inflammation research, immunology, and cell and molecular biology.
Book Synopsis Genetics of Rare Autoimmune Diseases by : Javier Martín
Download or read book Genetics of Rare Autoimmune Diseases written by Javier Martín and published by Springer. This book was released on 2019-05-29 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main aim of this volume is to provide an updated overview of the genetic basis of a group of complex disorders that are considered rare individually, but show a relatively high prevalence on the whole in developed countries: the rare autoimmune diseases. These are chronic disorders that involve long and expensive treatments with considerable side effects that may dramatically reduce the quality of life of affected people. Therefore, shedding light into their pathologic mechanisms is a major concern given their growing social and economic awareness and impact. General sections include different chapters on single entities as systemic lupus and sclerosis, Behçet’s disease, Sjogren’s syndrome and polymiositis, and sections devoted to autoimmune vasculitis, hepatic autoimmune conditions, as well as those affecting the nervous system, and a concluding chapter in which the shared predisposition amongst all diseases is discussed. All the chapters are given a homogeneous scheme in which the authors explain the clinical singularities of every disease and report the recent breakthrough discoveries related to them, giving a critical interpretation and suggesting future perspectives. All contributors are renowned researchers with high expertise in each disease. Due to the exponential increase in our understanding of the genetic causes of these complex diseases, a major advance in biomedical discovery is taking place. However, most of the achievements in this field are very recent and there is a lack of bibliography gathering them together. This book is thus filling a gap and will prove a useful companion to clinicians in the first place (internists, rheumatologists, clinical immunologists, and hematologists) but also to basic and applied researchers.
Book Synopsis Genomics in Rheumatic Diseases, An Issue of Rheumatic Disease Clinics of North America by : S. Louis Bridges Jr.
Download or read book Genomics in Rheumatic Diseases, An Issue of Rheumatic Disease Clinics of North America written by S. Louis Bridges Jr. and published by Elsevier Health Sciences. This book was released on 2017-08-01 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Rheumatic Disease Clinics focuses on Genetics. Article topics cover: Genetic Influences on Susceptibility and Severity of Rheumatoid Arthritis; HLA-disease associations in rheumatoid arthritis; Autoinflammatory Syndromes as a Model of Monogenic Diseases; Genomic Influences on Hyperuricaemia and Gout; Genetics of Systemic Lupus Erythematosus; Genetics of Ankylosing Spondylitis;Genetics of Scleroderma; Genetics of Osteoarthritis; Genetics of Juvenile Inflammatory Arthritis; Genetic Influences on Treatment Response in Rheumatic Diseases; Integrative approaches/computational biology; Future directions of genetic research in rheumatic diseases; and Population genetics and natural selection in rheumatic disease.
Book Synopsis Absolute Rheumatology Review by : Petros Efthimiou
Download or read book Absolute Rheumatology Review written by Petros Efthimiou and published by Springer Nature. This book was released on 2019-09-13 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a concise and up-to-date review of key rheumatology topics along with extensive practice questions to assist in preparing for the American Board of Internal Medicine (ABIM) Rheumatology Certification Exam. Each chapter focuses on a single disease and starts with a short review (primarily tables and figures) to highlight the main points and key issues. The review is followed by 10-20 board-style multiple choice questions with detailed explanations for each topic. The chapters and associated preparation questions are written by established experts from top institutions in the United States. The book concludes with a 50-question practice test reflecting the format used by the ABIM Board Certification Exam. Absolute Rheumatology Review is an essential resource for not only graduate students, residents, and fellows in rheumatology and internal medicine studying for board exams but also rheumatologists, physicians, and related professionals preparing for recertification.
Book Synopsis Seronegative Polyarthritis by : Verna Wright
Download or read book Seronegative Polyarthritis written by Verna Wright and published by Elsevier Science & Technology. This book was released on 1976 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Psoriatic and Reactive Arthritis by : Christopher T. Ritchlin
Download or read book Psoriatic and Reactive Arthritis written by Christopher T. Ritchlin and published by Elsevier Health Sciences. This book was released on 2007-01-01 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new companion to Hochberg et al.'s Rheumatology masterwork focuses on the momentous recent advances in our understanding of the genetics and immunology of psoriatic and reactive arthritis, and their implications for diagnosis and management. Leading international authorities explore new concepts in genetic and pathogenic mechanisms and early diagnosis; provide comprehensive, well-illustrated coverage of clinical features; evaluate the very latest therapeutic options, including biologics; and discuss clinical outcome measures. Examines the very latest pathogenic mechanisms and diagnostic criteria, providing the necessary tools for early diagnosis and monitoring of disease progression. Offers comprehensive coverage of the clinical manifestations of psoriatic and reactive arthritis, including a 'mini atlas' of color plates.Examines the pros and cons of the available therapeutic options, including the very latest biological as well as traditional therapies.Includes practical discussions of clinical outcome measures, delivering ongoing tools for assessment of function, disease activity, and quality of life.
Book Synopsis Principles of Molecular Rheumatology by : George C. Tsokos
Download or read book Principles of Molecular Rheumatology written by George C. Tsokos and published by Springer Science & Business Media. This book was released on 2000-07-24 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: George Tsokos and a panel of authoritative clinicians and researchers synthesize the latest findings from across cell and molecular biology with the basic principles of rheumatology to create the first textbook of molecular rheumatology. These established experts describe the biochemical mechanisms by which apoptosis, cell signaling, complement, lipids, and viruses contribute to disease expression, and detail both immune and nonimmune cell function in rheumatic diseases. Their review of the major rheumatic diseases integrates the cellular, biochemical, and molecular biological mechanisms that are important in rheumatic disease pathogenesis. Path-breaking and illuminating, Principles of Molecular Rheumatology expands the envelope of clinical understanding to reveal the biological roots underlying rheumatologic disease, as well as the nature and roles of the powerful new therapeutics now emerging for its optimal treatment.
Book Synopsis Oxford Textbook of Rheumatology by : Philip Conaghan
Download or read book Oxford Textbook of Rheumatology written by Philip Conaghan and published by Oxford University Press. This book was released on 2013-10 with total page 1553 pages. Available in PDF, EPUB and Kindle. Book excerpt: A strong clinical emphasis is present throughout this volume from the first section of commonly presenting problems through to the section addressing problems shared with a range of other clinical sub-specialties.
Book Synopsis Textbook of Pediatric Rheumatology E-Book by : James T. Cassidy
Download or read book Textbook of Pediatric Rheumatology E-Book written by James T. Cassidy and published by Elsevier Health Sciences. This book was released on 2010-10-15 with total page 817 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook of Pediatric Rheumatology examines the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents, detailing the presentation, differential diagnosis, course, management, and prognosis of every major condition. Drs. James T. Cassidy, Ross E. Petty, Ronald M. Laxer, and Carol B. Lindsley discuss recent developments in diagnosis, treatment, genetics, immunology, imaging, and more. Diagnose and treat effectively through exhaustive reviews of the complex symptoms and signs and lab abnormalities that characterize these clinical disorders. Choose treatment protocols based on the best scientific evidence available today. Apply the knowledge and experience of the leading experts in the field. Keep current with coverage of new topics including macrophage activation syndrome, pediatric sarcoidosis, uveitis, imaging, and occupational and physical therapy. Tap into detailed discussions of recent advances in the field, new research on the immunologic mechanisms of inflammatory disease, and new developments on biologic treatments for arthritis in ten new chapters. Master complex concepts and key techniques with a full-color design and full-color illustrations.
Book Synopsis Behçet's Disease by : Yoshiaki Ishigatsubo
Download or read book Behçet's Disease written by Yoshiaki Ishigatsubo and published by Springer. This book was released on 2014-12-03 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, besides reviewing basic and clinical aspects of Behçet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease. Although the cause of Behçet's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- Behçet's disease. Behçet's Disease: From Genetics to Therapies provides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in Behçet's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons.
Book Synopsis Primer on the Rheumatic Diseases by : John H. Klippel
Download or read book Primer on the Rheumatic Diseases written by John H. Klippel and published by . This book was released on 1997 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive textbook for health-care professionsl and students covering the rheumatic diseases, including arthritis, lupus, osteoporosis, fibromyalgia and more.
Book Synopsis Skills in Rheumatology by : Hani Almoallim
Download or read book Skills in Rheumatology written by Hani Almoallim and published by Springer Nature. This book was released on 2021-01-05 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access book presents practical approaches to managing patients affected by various rheumatological diseases, allowing readers to gain a better understanding of the various clinical expressions and problems experienced by these patients. Discussing rheumatology from an organ systems perspective, it highlights the importance ofdetailed musculoskeletal examinations when treating patients affected by rheumatological diseases. The book first explores the latest diagnostic approaches and offers key tips for accurate musculoskeletal examinations before addressing the various treatment modalities, with a particular focus on the most common joints involved in rheumatoid arthritis: the wrists and the metacarpophalangeal joints (2nd and 3rd). Featuring easy-to-understand flow diagrams and explaining the common medical problems associated with rheumatic disease, such as shortness of breath and anemia, it is not only a valuable resource to rheumatologists, but will also appeal to medical students, junior residents, and primary healthcare physicians.
Book Synopsis Pathology and Pathobiology of Rheumatic Diseases by : Hans G. Fassbender
Download or read book Pathology and Pathobiology of Rheumatic Diseases written by Hans G. Fassbender and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathology and Pathobiology of Rheumatic Diseases glows with the uncommon precision of the pathologist, the clarity of the tea cher, and the unswerving commitment of the investigator. Fass bender has produced a major contribution to the literature of rheumatic diseases. The practical experience and wisdom brought together in this book, substantiated by excellent exam ples of histopathology, produce a landmark for all who have made the study of rheumatic diseases their profession. The enor mous achievements made in molecular biology, genetics, struc tural biochemistry, and clinical science have been assembled in this book to interact in a meaningful way with the anatomical histology of the rheumatic diseases. It is not easy for any single investigator to paint the picture of a disease process, from its clinical description to its mechanisms, and then to a defined hypothesis, and finally an understanding. Nonetheless, Fassbender has done this in a clear and convincing way that integrates our current knowledge of this group of dis eases. Scientific discovery in medicine moves from the bedside to the bench, back to the bedside, and then back to the bench, etc. It is this iterative process of new observation and new discovery that has given us the achievements in medicine over the past century.
Book Synopsis Current Rheumatology Diagnosis & Treatment by : John B. Imboden
Download or read book Current Rheumatology Diagnosis & Treatment written by John B. Imboden and published by McGraw-Hill/Appleton & Lange. This book was released on 2004 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ideal quick reference for primary care providers, specialists, and trainees, this accessible resource offers up-to-date assessment and management solutions for the entire range of rheumatologic diseases.
Book Synopsis Rheumatology Secrets by : Sterling West, MD, MACP, FACR
Download or read book Rheumatology Secrets written by Sterling West, MD, MACP, FACR and published by Elsevier Health Sciences. This book was released on 2014-11-05 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stay up to date on the latest common and uncommon rheumatic disorders with Rheumatology Secrets Plus. This enhanced medical reference book addresses the treatment of common and uncommon rheumatic disorders, with each chapter reviewing basic immunology and pathophysiology, important disease manifestations, and practical management issues. The user-friendly style of the popular Secrets Series® makes this updated volume a valuable addition to your library! Review basic immunology and pathophysiology, important disease manifestations, and practical management issues related to rheumatic disorders. Apply the latest knowledge and techniques with content thoroughly updated by leaders in the field. Quickly review key concepts with improved "Plus" formatting, such as larger figures and easier-to-read text. Enhance your reference power through a question-and-answer format, bulleted lists, mnemonics, "Key Points" summaries, lists of useful web sites, and practical tips from the authors. Improve content knowledge with a special chapter containing "Top 100 Secrets," providing an overview of essential material for last-minute study or self-assessment. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
