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Genetic Polymorphisms
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Book Synopsis Genetic Polymorphism and cancer susceptibility by : Aga Syed Sameer
Download or read book Genetic Polymorphism and cancer susceptibility written by Aga Syed Sameer and published by Springer Nature. This book was released on 2021-04-22 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the role of genetic polymorphism in susceptibility to cancers. The book explores the understanding of differences between the genetic polymorphisms and mutations.It reviews the mechanisms underlying the effect of polymorphism in genes encoding proteins that play an essential role in metabolism, signal transduction, cell cycle, and DNA repair mechanisms. Further, it investigates various techniques that are used for analyzing the genetic polymorphisms. The book contains many chapters which summarize the importance of genetic information obtained from polymorphism-based pharmaco-genetic tests to predict better drug response and life-threatening adverse reactions to chemotherapeutic agents, help in understanding of the impact of SNPs on gene function, and gives overview of the different SNP databases for examination. This book, therefore, serves as an essential guidebook for independent researchers as well as institutions working in this specialised field.
Book Synopsis Genetic Polymorphisms by : Narasimha Reddy Parine
Download or read book Genetic Polymorphisms written by Narasimha Reddy Parine and published by BoD – Books on Demand. This book was released on 2017-09-06 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this Genetic Polymorphisms book is to rehighlight and provide few updates on the role of genetic polymorphisms in medicine and agriculture, which void emerging opinion on "full death" of genetic polymorphisms as useful genetic markers. Chapters presented here demonstrate the future benefit of SNPs in many genetic studies as well as prognosis disease and diagnosis.
Book Synopsis The Recent Topics in Genetic Polymorphisms by : Mahmut Çalışkan
Download or read book The Recent Topics in Genetic Polymorphisms written by Mahmut Çalışkan and published by BoD – Books on Demand. This book was released on 2020-05-13 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book in your hands presents chapters revealing the magnitude of genetic polymorphisms that exist in different kinds of living beings. Natural populations contain a considerable amount of genetic change, which provides a genomic flexibility that can be used as a raw material for adaptation to changing environmental conditions. The analysis of genetic polymorphisms provides information about DNA sequence changes at a given locus. The increasing availability of PCR-based molecular markers allows for the detailed analyses and the detection of genetic changes influencing some important traits. The purpose of this book is to provide a glimpse into the dynamic process of genetic polymorphisms by presenting the thoughts of scientists engaged in the generation of new ideas and techniques employed for the assessment of genetic polymorphisms. The book should prove useful to students, researchers and experts in the area of molecular genetics.
Book Synopsis Genetic Polymorphism and Disease by : Syed Sameer Aga
Download or read book Genetic Polymorphism and Disease written by Syed Sameer Aga and published by CRC Press. This book was released on 2022-12-06 with total page 1256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic polymorphisms are important determinants of phenotypic variations and may modulate the risk to or even cause various diseases including genetic disorders and multifactorial diseases. Genetic polymorphisms also serve as important genetic, population and evolutionary markers that allow the study of genetic and evolutionary aspects of individuals, populations and organisms and aid in tracing the evolutionary and parental lineages. Genetic polymorphisms in low penetrance genes are responsible for the alterations in the gene expression of critical signal transduction proteins and metabolic enzymes. Some of these polymorphisms are linked to increased susceptibility to various diseases especially cancers, cardiovascular diseases, immune disorders, neurological pathologies. This book collates the reviews on the roles played by polymorphisms in critical metabolic, signal transduction, cell cycle or DNA repair genes either directly or indirectly in the disease mechanisms. The focus is on various techniques for identifying the various Single Nucleotide Polymorphisms (SNPs). Polymorphism studies document the affect SNPs, and their expressions have upon the functionality of the enzymes, proteins. Key Features Describes the genetic polymorphism and its various types Discusses the role of genetic polymorphisms in modulating the risk of various human diseases Explores various molecular techniques used for detecting GPs Characterizes the role of SNPs in modulating the susceptibility of human diseases Provides a genetic basis for individual variations in response to therapeutics
Book Synopsis Genes, Polymorphisms, and the Making of Societies by : Hippokratis Kiaris
Download or read book Genes, Polymorphisms, and the Making of Societies written by Hippokratis Kiaris and published by Universal-Publishers. This book was released on 2021-06-15 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our genes determine to a large extent who we are and why we are different from others. In this book, Hippokratis Kiaris explores how various genetic polymorphisms in different ethnic populations may affect the development of distinct cultures and eventually historical decisions. It should be read by anybody interested in history, anthropology, behavior, psychology or genetics. The reader will find clues linking together these scientific disciplines and how such genetically determined behavioral traits may play an undervalued, as yet, role in shaping historical outcomes. The book initially describes some basic concepts on genetics and proceeds with an outline of human evolution, the journey of early humans Out-of-Africa, and the colonization of Earth by different human populations that eventually resulted in the development of different cultures. Then, by focusing on the two major prototype cultural lines, the Eastern and the Western, the author discusses differences in the corresponding civilizations in view of specific genetic polymorphisms that affect behavior and differ in frequencies between people of Asian and European origin. Finally, in view of the contemporary increasing tendency for cultural globalization, the book attempts to predict future trends on cultures and behavioral patterns. In this revised and extended second edition new data are included and new chapters, focusing on how sets of genes, as opposed to individual ones, coexist in different populations and may potentially impact cultural divergence throughout history.
Book Synopsis Genetic Polymorphisms by : Mahmut Çalışkan
Download or read book Genetic Polymorphisms written by Mahmut Çalışkan and published by BoD – Books on Demand. This book was released on 2022-05-04 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a glimpse into the dynamic process of genetic polymorphism by presenting studies carried out on different kinds of organisms at the DNA level or gene expression level. Chapters address such topics as genetic polymorphism in animals, gametocyte biomarkers, thrombotic disorders, prostate cancer, and more.
Book Synopsis Genetic Polymorphisms and Susceptibility to Disease by : Mark Steven Miller
Download or read book Genetic Polymorphisms and Susceptibility to Disease written by Mark Steven Miller and published by CRC Press. This book was released on 2000-04-27 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Polymorphisms and Susceptibity to Disease provides a reference for established researchers in genetic research. The book provides a broad but thorough overview of how allelic gene differences influence disease susceptibility in the human population, and will be a useful reference to researchers across a range of disciplines, for example, oncology, cardiology and immunology . In addition, this book serves as a primer for students first entering the field of genetic research.
Book Synopsis Genetic Polymorphisms: An Integrated Approach by : Vince Clinton
Download or read book Genetic Polymorphisms: An Integrated Approach written by Vince Clinton and published by Murphy & Moore Publishing. This book was released on 2021-11-16 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: The simultaneous occurrence of two or more discontinuous alleles or genotypes in a population is termed as genetic polymorphism. Most genetic polymorphisms are silent and do not interfere with the expression or function of a gene. Polymorphisms are classified into single nucleotide polymorphisms, small scale insertions and deletions, polymorphic repetitive elements, and microsatellites. The single nucleoid changes which happen in the genome in a particular location are termed as single nucleoid polymorphisms (SNPs). They are associated with both coding and non-coding regions. In humans, more than 100 million SNPs have been recognised. This book covers in detail some existent theories and innovative concepts revolving around genetic polymorphisms. It includes some of the vital pieces of work being conducted across the world, on various topics related to genetic polymorphism. Those in search of information to further their knowledge will be greatly assisted by this book.
Book Synopsis Cytokine Gene Polymorphisms in Multifactorial Conditions by : Koen Vandenbroeck
Download or read book Cytokine Gene Polymorphisms in Multifactorial Conditions written by Koen Vandenbroeck and published by CRC Press. This book was released on 2006-06-21 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: The literature on cytokine genetics is vast, so vast that it is now practically beyond the time or logistical constraints of most scientists to successfully keep pace with it. A compilation of the latest research, Cytokine Gene Polymorphisms in Multifactorial Conditions brings together, reviews, and structures up-to-date information on polymorphism
Book Synopsis Genetic Diversity and Disease Susceptibility by : Yamin Liu
Download or read book Genetic Diversity and Disease Susceptibility written by Yamin Liu and published by BoD – Books on Demand. This book was released on 2018-10-17 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymorphism or variation in DNA sequence can affect individual phenotypes such as color of skin or eyes, susceptibility to diseases, and response to drugs, vaccines, chemicals, and pathogens. Especially, the interfaces between genetics, disease susceptibility, and pharmacogenomics have recently been the subject of intense research activity. This book is a self-contained collection of valuable scholarly papers related to genetic diversity and disease susceptibility, pharmacogenomics, ongoing advances in technology, and analytic methods in this field. The book contains nine chapters that cover the three main topics of genetic polymorphism, genetic diversity, and disease susceptibility and pharmacogenomics. Hence, this book is particularly useful to academics, scientists, physicians, pharmacists, practicing researchers, and postgraduate students whose work relates to genetic polymorphisms.
Book Synopsis Genetic Variation and Its Maintenance by : Derek Frank Roberts
Download or read book Genetic Variation and Its Maintenance written by Derek Frank Roberts and published by Cambridge University Press. This book was released on 1986-10-30 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume considers the genetic variability of human populations, particularly in the tropics: its origins and maintenance, and its contribution to the phenotypic variability of complex characters. The first section deals with the ways of analysing genetic variation and provides a valuable review of relevant developments in molecular biology. The origin and maintenance of genetic diversity is considered in the second section with data presented for Pacific, African, Asian and Central American populations. The final section concerns characters in which the genetic contribution to variability is complex and shows how such characters may be used to elucidate biological problems of affinity and differentiation, of adaptation and survival. Published as part of the Decade of the Tropics research programme of the International Union of Biological Sciences, this volume will be of particular interest to human geneticists, physical and biological anthropologists.
Book Synopsis Tandem Repeat Polymorphisms by : Anthony J. Hannan
Download or read book Tandem Repeat Polymorphisms written by Anthony J. Hannan and published by Springer Science & Business Media. This book was released on 2013-07-30 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the role of tandem repeat polymorphisms (TRPs) in genetic plasticity, evolution, development, biological processes, neural diversity, brain function, dysfunction and disease. There are hundreds of thousands of unique tandem repeats in the human genome and their polymorphic distributions have the potential to greatly influence functional diversity and disease susceptibility. Recent discoveries in this expanding field are critically reviewed and discussed in a range of subsequent chapters, with a focus on the role of TRPs and their various gene products in evolution, development, diverse molecular and cellular processes, brain function and disease.
Book Synopsis Human Blood Cells: Consequences Of Genetic Polymorphisms And Variations by : May-jean King
Download or read book Human Blood Cells: Consequences Of Genetic Polymorphisms And Variations written by May-jean King and published by World Scientific. This book was released on 2000-07-04 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important book uses selected molecules expressed on erythrocytes, lymphocytes, platelets and granulocytes to illustrate how genetic polymorphisms and variations in these molecules can affect their structure and function in mature human blood cells. The examples described tend to have a clinical association. Human blood group antigens and HLA antigens are classic examples of genetic polymorphism and they are important in blood transfusion and organ transplantation, respectively. In common with the blood group antigens, the polymorphic and variant antigens on platelets and granulocytes can be targets for antibodies in feto-maternal antigen incompatibility and transfusion reactions. Certain inherited haemolytic anaemias can be attributed to some of the polymorphic and variant forms of erythrocyte anion transport protein, spectrin, and glucose-6-phosphate dehydrogenase which exhibit abnormal structural or functional properties. Similarly, the study of cytokine gene polymorphism can provide a further understanding of the immune/inflammatory diseases and allogeneic transplantation./a
Book Synopsis Understanding Insulin and Insulin Resistance by : Anil Gupta
Download or read book Understanding Insulin and Insulin Resistance written by Anil Gupta and published by Elsevier. This book was released on 2021-11-17 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Insulin and Insulin Resistance is written in a simple and clear language illustrated with diagrams that show the complex interplay of various factors in the initiation of insulin resistance. The design is systematic and meticulous, portraying topics in a flow from simple to complex. This resource is intended for a broad audience spanning across biochemistry, medicine, dentistry, academia, physicians, and research scholars. It extends the approach to biochemistry, physiology, metabolism of insulin along with the coverage of pathophysiology of insulin resistance, its effects on the body tissues, and its analysis on insulin resistance syndrome.
Book Synopsis Genetic Polymorphisms and Diseases in Man by : Bracha Ramot
Download or read book Genetic Polymorphisms and Diseases in Man written by Bracha Ramot and published by . This book was released on 1974 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Genes, Polymorphisms, and the Making of Societies by : Hippokratis Kiaris
Download or read book Genes, Polymorphisms, and the Making of Societies written by Hippokratis Kiaris and published by Universal Publishers. This book was released on 2012 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our genes determine to a large extent who we are as individuals and why we are different from the other human beings. In this book, Hippokratis Kiaris explores how various genetic polymorphisms in different ethnic populations may affect the development of distinct cultures and eventually historical decisions. It should be read by anybody interested in history, anthropology, behavior, psychology or genetics. The reader will find clues linking together these scientific disciplines and how such genetically determined behavioral traits may play an undervalued, as yet, role in shaping historical outcomes. The book initially describes some basic concepts on genetics and proceeds with an outline of human evolution, the journey of early humans Out-of-Africa, and the colonization of Earth by different human populations that eventually resulted in the development of different cultures. Then, by focusing on the two major prototype cultural lines, the Eastern and the Western, the author discusses differences in the corresponding civilizations in view of specific genetic polymorphisms that affect behavior and differ in frequencies between people of Asian and European origin. Finally, in view of the contemporary increasing tendency for cultural globalization, the book attempts to predict future trends on cultures and behavioral patterns.
Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
