Genetic Mapping and DNA Sequencing: Principles, Analysis and Applications

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Publisher : Callisto Reference
ISBN 13 : 9781641165464
Total Pages : 215 pages
Book Rating : 4.1/5 (654 download)

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Book Synopsis Genetic Mapping and DNA Sequencing: Principles, Analysis and Applications by : Ashton Ward

Download or read book Genetic Mapping and DNA Sequencing: Principles, Analysis and Applications written by Ashton Ward and published by Callisto Reference. This book was released on 2021-11-16 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proximate DNA sequences on a chromosome are inherited together during sexual reproduction. This tendency of DNA sequences is called genetic linkage. On a chromosome, the closer two genes are, the higher are their chances of being inherited together and lower are the chances of recombination between them. Gene mapping refers to the set of methods that allow the identification of the locus of a gene as well as the distances between genes. It offers evidences regarding the genes that are responsible for the inheritance of disease from parent to child, and also provides clues regarding the location of the genes and the chromosome where they are located. DNA sequencing is the process that determines the nucleic acid sequence or the order of nucleotides in the DNA. It encompasses all methods that can determine the order of the four bases- thymine, guanine, adenine and cytosine. The development of genetic maps and the successful sequencing of the human genome have advanced the frontiers of genetics and medical science. This book aims to shed light on some of the unexplored aspects of genetic mapping and DNA sequencing and the recent researches in these domains. It includes some of the vital pieces of work being conducted across the world, on various topics related to these fields. This book will prove immensely beneficial to geneticists, genetic engineers, students and researchers associated with these areas of study.

Mapping and Sequencing the Human Genome

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Publisher : National Academies Press
ISBN 13 : 0309038405
Total Pages : 128 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Mapping and Sequencing the Human Genome by : National Research Council

Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

DNA Sequencing

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Publisher : BoD – Books on Demand
ISBN 13 : 9535105647
Total Pages : 188 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis DNA Sequencing by : Anjana Munshi

Download or read book DNA Sequencing written by Anjana Munshi and published by BoD – Books on Demand. This book was released on 2012-04-20 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates methods of DNA sequencing and its application in plant, animal and medical sciences. It has two distinct sections. The one includes 2 chapters devoted to the DNA sequencing methods and the second includes 6 chapters focusing on various applications of this technology. The content of the articles presented in the book is guided by the knowledge and experience of the contributing authors. This book is intended to serve as an important resource and review to the researchers in the field of DNA sequencing.

Biological Sequence Analysis

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Publisher : Cambridge University Press
ISBN 13 : 113945739X
Total Pages : 372 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Biological Sequence Analysis by : Richard Durbin

Download or read book Biological Sequence Analysis written by Richard Durbin and published by Cambridge University Press. This book was released on 1998-04-23 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.

Genetic Mapping and DNA Sequencing

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Publisher : Springer Science & Business Media
ISBN 13 : 1461207517
Total Pages : 229 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Genetic Mapping and DNA Sequencing by : Terry Speed

Download or read book Genetic Mapping and DNA Sequencing written by Terry Speed and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics mapping, physical mapping and DNA sequencing are the three key components of the human and other genome projects. Statistics, mathematics and computing play important roles in all three, as well as in the uses to which the mapping and sequencing data are put. This volume edited by key researchers Mike Waterman and Terry Speed reviews recent progress in the area, with an emphasis on the theory and application of genetic mapping.

Sequence — Evolution — Function

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Publisher : Springer Science & Business Media
ISBN 13 : 1475737831
Total Pages : 482 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Sequence — Evolution — Function by : Eugene V. Koonin

Download or read book Sequence — Evolution — Function written by Eugene V. Koonin and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.

Bioinformatics

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Publisher : Springer Science & Business Media
ISBN 13 : 0387927387
Total Pages : 450 pages
Book Rating : 4.3/5 (879 download)

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Book Synopsis Bioinformatics by : David Edwards

Download or read book Bioinformatics written by David Edwards and published by Springer Science & Business Media. This book was released on 2009-09-03 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics is a relatively new field of research. It evolved from the requirement to process, characterize, and apply the information being produced by DNA sequencing technology. The production of DNA sequence data continues to grow exponentially. At the same time, improved bioinformatics such as faster DNA sequence search methods have been combined with increasingly powerful computer systems to process this information. Methods are being developed for the ever more detailed quantification of gene expression, providing an insight into the function of the newly discovered genes, while molecular genetic tools provide a link between these genes and heritable traits. Genetic tests are now available to determine the likelihood of suffering specific ailments and can predict how plant cultivars may respond to the environment. The steps in the translation of the genetic blueprint to the observed phenotype is being increasingly understood through proteome, metabolome and phenome analysis, all underpinned by advances in bioinformatics. Bioinformatics is becoming increasingly central to the study of biology, and a day at a computer can often save a year or more in the laboratory. The volume is intended for graduate-level biology students as well as researchers who wish to gain a better understanding of applied bioinformatics and who wish to use bioinformatics technologies to assist in their research. The volume would also be of value to bioinformatics developers, particularly those from a computing background, who would like to understand the application of computational tools for biological research. Each chapter would include a comprehensive introduction giving an overview of the fundamentals, aimed at introducing graduate students and researchers from diverse backgrounds to the field and bring them up-to-date on the current state of knowledge. To accommodate the broad range of topics in applied bioinformatics, chapters have been grouped into themes: gene and genome analysis, molecular genetic analysis, gene expression analysis, protein and proteome analysis, metabolome analysis, phenome data analysis, literature mining and bioinformatics tool development. Each chapter and theme provides an introduction to the biology behind the data describes the requirements for data processing and details some of the methods applied to the data to enhance biological understanding.

GENE CLONING AND GENOMICS (Principles and Applications)

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Publisher : Lulu.com
ISBN 13 : 138715592X
Total Pages : 214 pages
Book Rating : 4.3/5 (871 download)

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Book Synopsis GENE CLONING AND GENOMICS (Principles and Applications) by : Dr. RAVISHANKAR B.V.

Download or read book GENE CLONING AND GENOMICS (Principles and Applications) written by Dr. RAVISHANKAR B.V. and published by Lulu.com. This book was released on with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gene-Mapping Techniques and Applications

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Publisher : CRC Press
ISBN 13 : 9780824785352
Total Pages : 360 pages
Book Rating : 4.7/5 (853 download)

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Book Synopsis Gene-Mapping Techniques and Applications by : Lawrence B. Schook

Download or read book Gene-Mapping Techniques and Applications written by Lawrence B. Schook and published by CRC Press. This book was released on 1991-05-15 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains current strategies for mapping genomes of higher organisms and explores applications of gene mapping to agriculturally important species of plants and animals. It also explores the experimental techniques used for genetic and physical mapping of genes.

Next-Generation Sequencing and Sequence Data Analysis

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Publisher : Bentham Science Publishers
ISBN 13 : 1681080923
Total Pages : 160 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Next-Generation Sequencing and Sequence Data Analysis by : Kuo Ping Chiu

Download or read book Next-Generation Sequencing and Sequence Data Analysis written by Kuo Ping Chiu and published by Bentham Science Publishers. This book was released on 2015-11-04 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nucleic acid sequencing techniques have enabled researchers to determine the exact order of base pairs - and by extension, the information present - in the genome of living organisms. Consequently, our understanding of this information and its link to genetic expression at molecular and cellular levels has lead to rapid advances in biology, genetics, biotechnology and medicine. Next-Generation Sequencing and Sequence Data Analysis is a brief primer on DNA sequencing techniques and methods used to analyze sequence data. Readers will learn about recent concepts and methods in genomics such as sequence library preparation, cluster generation for PCR technologies, PED sequencing, genome assembly, exome sequencing, transcriptomics and more. This book serves as a textbook for students undertaking courses in bioinformatics and laboratory methods in applied biology. General readers interested in learning about DNA sequencing techniques may also benefit from the simple format of information presented in the book.

Genome Mapping

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Publisher : CreateSpace
ISBN 13 : 1453735437
Total Pages : 208 pages
Book Rating : 4.4/5 (537 download)

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Book Synopsis Genome Mapping by : Jon Schiller

Download or read book Genome Mapping written by Jon Schiller and published by CreateSpace. This book was released on 2010-08-07 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Your author decided to write this book about Genome Mapping after attending a Dinner Lecture for Caltech Alumni living in the Santa Barbara County area of Mid-Coast California Dr David Barker, BS 1963 Caltech & PhD in Biochemistry from Brandeis University, gave a slide presentation on DNA sequencing and what it can tell you. In my quest for more knowledge about this exciting area of biochemistry, I sought more information about Genome Mapping and Entire DNA Sequencing from the Google and Yahoo search engines. As is common in Internet Research, I found a great deal of research was taking place worldwide. It was my objective to summarize this research in this book so my readers could learn what is happening and where to find more information about this important area of Biochemistry. One possibility is modifying your DNA to reduce susceptibility to certain diseases..perhaps we will be able to reduce our risk of cancer. One of my good friends died recently of Prostate Cancer, so my interest in combating Cancer has been intensified.

Principles of Genome Analysis

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Publisher : Wiley-Blackwell
ISBN 13 : 9780865429468
Total Pages : 148 pages
Book Rating : 4.4/5 (294 download)

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Book Synopsis Principles of Genome Analysis by : S. B. Primrose

Download or read book Principles of Genome Analysis written by S. B. Primrose and published by Wiley-Blackwell. This book was released on 1995-01 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome mapping has arguably been the single most significant advance in biomedicine in the past decade or more. A complete map of the genome of selected model organisms should revolutionize our understanding of biology. The ultimate goal, a map of the human genome, will impact hugely on the diagnosis and treatment of human genetic disorders. Principles of Genome Analysis should be invaluable to anyone contemplating genome mapping, from the experienced geneticist to the clinical researcher.

Next Generation Sequencing

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Publisher : BoD – Books on Demand
ISBN 13 : 9535122401
Total Pages : 466 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Next Generation Sequencing by : Jerzy Kulski

Download or read book Next Generation Sequencing written by Jerzy Kulski and published by BoD – Books on Demand. This book was released on 2016-01-14 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.

Human Genome

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Publisher :
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Human Genome by :

Download or read book Human Genome written by and published by . This book was released on 1992 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Applications of RNA-Seq and Omics Strategies

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Publisher : BoD – Books on Demand
ISBN 13 : 9535135031
Total Pages : 330 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Applications of RNA-Seq and Omics Strategies by : Fabio Marchi

Download or read book Applications of RNA-Seq and Omics Strategies written by Fabio Marchi and published by BoD – Books on Demand. This book was released on 2017-09-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: The large potential of RNA sequencing and other "omics" techniques has contributed to the production of a huge amount of data pursuing to answer many different questions that surround the science's great unknowns. This book presents an overview about powerful and cost-efficient methods for a comprehensive analysis of RNA-Seq data, introducing and revising advanced concepts in data analysis using the most current algorithms. A holistic view about the entire context where transcriptome is inserted is also discussed here encompassing biological areas with remarkable technological advances in the study of systems biology, from microorganisms to precision medicine.

Analytical Techniques In DNA Sequencing

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Publisher : CRC Press
ISBN 13 : 1420029088
Total Pages : 252 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Analytical Techniques In DNA Sequencing by : Brian K. Nunnally

Download or read book Analytical Techniques In DNA Sequencing written by Brian K. Nunnally and published by CRC Press. This book was released on 2005-06-23 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: While one marvels at the DNA generated by the Human Genome Project, perhaps just as significant and fascinating is the development of the amazing analytical technology that has permitted us entry into the genomic era and a whole new level of scientific understanding. Analytical Techniques in DNA Sequencing takes a look at the various DNA

Next-Generation Sequencing Data Analysis

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Publisher : CRC Press
ISBN 13 : 1482217899
Total Pages : 258 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Next-Generation Sequencing Data Analysis by : Xinkun Wang

Download or read book Next-Generation Sequencing Data Analysis written by Xinkun Wang and published by CRC Press. This book was released on 2016-04-06 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Practical Guide to the Highly Dynamic Area of Massively Parallel SequencingThe development of genome and transcriptome sequencing technologies has led to a paradigm shift in life science research and disease diagnosis and prevention. Scientists are now able to see how human diseases and phenotypic changes are connected to DNA mutation, polymorphi