Mapping and Sequencing the Human Genome

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Author :
Publisher : National Academies Press
ISBN 13 : 0309038405
Total Pages : 128 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Mapping and Sequencing the Human Genome by : National Research Council

Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Genetic Mapping and DNA Sequencing

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461207517
Total Pages : 229 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Genetic Mapping and DNA Sequencing by : Terry Speed

Download or read book Genetic Mapping and DNA Sequencing written by Terry Speed and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics mapping, physical mapping and DNA sequencing are the three key components of the human and other genome projects. Statistics, mathematics and computing play important roles in all three, as well as in the uses to which the mapping and sequencing data are put. This volume edited by key researchers Mike Waterman and Terry Speed reviews recent progress in the area, with an emphasis on the theory and application of genetic mapping.

Gene Mapping, Discovery, and Expression

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Publisher : Springer Science & Business Media
ISBN 13 : 1597450979
Total Pages : 335 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Gene Mapping, Discovery, and Expression by : Minou Bina

Download or read book Gene Mapping, Discovery, and Expression written by Minou Bina and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completion of the sequence of the human genome represents an unpar- leled achievement in the history of biology. The project has produced nearly complete, highly accurate, and comprehensive sequences of genomes of s- eral organisms including human, mouse, drosophila, and yeast. Furthermore, the development of high-throughput technologies has led to an explosion of projects to sequence the genomes of additional organisms including rat, chimp, dog, bee, chicken, and the list is expanding. The nearly completed draft of genomic sequences from numerous species has opened a new era of research in biology and in biomedical sciences. In keeping with the interdisciplinary nature of the new scientific era, the chapters in Gene Mapping, Discovery, and Expression: Methods and Protocols recapitulate the necessity of integration of experimental and computational tools for solving - portant research problems. The general underlying theme of this volume is DNA sequence-based technologies. At one level, the book highlights the importance of databases, genome-browsers, and web-based tools for data access and ana- sis. More specifically, sequencing projects routinely deposit their data in p- licly available databases including GenBank, at the National Center of Biotechnology (NCBI) in the United States; EMBL, maintained by the European Bioinformatics Institute; and DDBJ, the DNA Data Bank of Japan. Currently, several browsers offer facile access to numerous genomic DNA sequences for gene mapping and data retrieval.

Genetic Mapping and DNA Sequencing: Principles, Analysis and Applications

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Author :
Publisher : Callisto Reference
ISBN 13 : 9781641165464
Total Pages : 215 pages
Book Rating : 4.1/5 (654 download)

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Book Synopsis Genetic Mapping and DNA Sequencing: Principles, Analysis and Applications by : Ashton Ward

Download or read book Genetic Mapping and DNA Sequencing: Principles, Analysis and Applications written by Ashton Ward and published by Callisto Reference. This book was released on 2021-11-16 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proximate DNA sequences on a chromosome are inherited together during sexual reproduction. This tendency of DNA sequences is called genetic linkage. On a chromosome, the closer two genes are, the higher are their chances of being inherited together and lower are the chances of recombination between them. Gene mapping refers to the set of methods that allow the identification of the locus of a gene as well as the distances between genes. It offers evidences regarding the genes that are responsible for the inheritance of disease from parent to child, and also provides clues regarding the location of the genes and the chromosome where they are located. DNA sequencing is the process that determines the nucleic acid sequence or the order of nucleotides in the DNA. It encompasses all methods that can determine the order of the four bases- thymine, guanine, adenine and cytosine. The development of genetic maps and the successful sequencing of the human genome have advanced the frontiers of genetics and medical science. This book aims to shed light on some of the unexplored aspects of genetic mapping and DNA sequencing and the recent researches in these domains. It includes some of the vital pieces of work being conducted across the world, on various topics related to these fields. This book will prove immensely beneficial to geneticists, genetic engineers, students and researchers associated with these areas of study.

Mapping our genes : the genome projects : how big, how fast?

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Author :
Publisher : DIANE Publishing
ISBN 13 : 142892258X
Total Pages : 215 pages
Book Rating : 4.4/5 (289 download)

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Book Synopsis Mapping our genes : the genome projects : how big, how fast? by :

Download or read book Mapping our genes : the genome projects : how big, how fast? written by and published by DIANE Publishing. This book was released on 1988 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genome Mapping

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Author :
Publisher : CreateSpace
ISBN 13 : 1453735437
Total Pages : 208 pages
Book Rating : 4.4/5 (537 download)

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Book Synopsis Genome Mapping by : Jon Schiller

Download or read book Genome Mapping written by Jon Schiller and published by CreateSpace. This book was released on 2010-08-07 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Your author decided to write this book about Genome Mapping after attending a Dinner Lecture for Caltech Alumni living in the Santa Barbara County area of Mid-Coast California Dr David Barker, BS 1963 Caltech & PhD in Biochemistry from Brandeis University, gave a slide presentation on DNA sequencing and what it can tell you. In my quest for more knowledge about this exciting area of biochemistry, I sought more information about Genome Mapping and Entire DNA Sequencing from the Google and Yahoo search engines. As is common in Internet Research, I found a great deal of research was taking place worldwide. It was my objective to summarize this research in this book so my readers could learn what is happening and where to find more information about this important area of Biochemistry. One possibility is modifying your DNA to reduce susceptibility to certain diseases..perhaps we will be able to reduce our risk of cancer. One of my good friends died recently of Prostate Cancer, so my interest in combating Cancer has been intensified.

The Handbook of Plant Genome Mapping

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Publisher : John Wiley & Sons
ISBN 13 : 352760443X
Total Pages : 402 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis The Handbook of Plant Genome Mapping by : Khalid Meksem

Download or read book The Handbook of Plant Genome Mapping written by Khalid Meksem and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: While the complete sequencing of the genomes of model organisms such as a multitude of bacteria and archaea, the yeast Saccharomyces cerevisiae, the worm Caenorhabditis elegans, the fly Drosophila melanogaster, and the mouse and human genomes have received much public attention, the deciphering of plant genomeswas greatly lagging behind. Up to now, only two plant genomes, one of the model plant Arabidopsis thaliana and one of the crop species rice (Oryza sativa) have been sequenced, though a series of other crop genome sequencing projects are underway. Notwithstanding this public bias towards genomics of animals and humans, it is nevertheless of great importance for basic and applied sciences and industries in such diverse fields as agriculture, breeding in particular, evolutionary genetics, biotechnology, and food science to know the composition of crop plant genomes in detail. It is equally crucial for a deeper understanding of the molecular basis of biodiversity and synteny. The Handbook of Genome Mapping: Genetic and Physical Mapping is the first book on the market to cover these hot topics in considerable detail, and is set apart by its combination of genetic and physical mapping. Throughout, each chapter begins with an easy-to-read introduction, also making the book the first reference designed for non-specialists and newcomers, too. In addition to being an outstanding bench work reference, the book is an excellent textbook for learning and teaching genomics, in particular for courses on genome mapping. It also serves as an up-to-date guide for seasoned researchers involved in the genetic and physical mapping of genomes, especially plant genomes.

Genome Mapping and Genomics in Human and Non-Human Primates

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Author :
Publisher : Springer
ISBN 13 : 3662463067
Total Pages : 305 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Genome Mapping and Genomics in Human and Non-Human Primates by : Ravindranath Duggirala

Download or read book Genome Mapping and Genomics in Human and Non-Human Primates written by Ravindranath Duggirala and published by Springer. This book was released on 2015-03-25 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes including multifactorial diseases (e.g., cardiovascular disease, type 2 diabetes, and obesity), anatomic characteristics (e.g., the craniofacial complex), and neurological and behavioral phenotypes (e.g., human brain structure and nonhuman primate behavior) are presented. Topics covered include linkage and association methods, gene expression, copy number variation, next-generation sequencing, comparative genomics, population structure, and a discussion of the Human Genome Project. Further included are discussions of the use of statistical genetic and genetic epidemiologic techniques to decipher the genetic architecture of normal and disease-related complex phenotypes using data from both humans and non-human primates.

Travelling Around the Human Genome

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Author :
Publisher : John Libbey Eurotext
ISBN 13 : 9782855985725
Total Pages : 210 pages
Book Rating : 4.9/5 (857 download)

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Book Synopsis Travelling Around the Human Genome by : Bertrand Jordan

Download or read book Travelling Around the Human Genome written by Bertrand Jordan and published by John Libbey Eurotext. This book was released on 1993 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt:

From Molecular Genetics to Genomics

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Publisher : Routledge
ISBN 13 : 1134334079
Total Pages : 447 pages
Book Rating : 4.1/5 (343 download)

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Book Synopsis From Molecular Genetics to Genomics by : Jean-Paul Gaudillière

Download or read book From Molecular Genetics to Genomics written by Jean-Paul Gaudillière and published by Routledge. This book was released on 2004-10-07 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the rise of genomics, the life sciences have entered a new era. Maps of genomes have become the icons for a comprehensive knowledge of the organism on a previously unattained level of complexity, and the organisation of genetic knowledge in maps has been a major driving force in the establishment of the discipline. This book provides a comprehensive history of molecular genetics and genomics. The first section of the book shows how the genetic cartography of classical genetics was linked to the molecular analysis of gene structure through the introduction of new model organisms such as bacteria and through the invention of new experimental tools such as gene transfer. The second section addresses the moral and political economy of human genome sequencing in all its technical, epistemic, social and economic complexity. With detailed analyses of the scientific practices of mapping and its illustration of the diversity of mapping practices this book is a significant contribution to the history of genetics. A companion volume from the same editors - Classical Genetic Research and Its Legacy: The Mapping Cultures of Twentieth Century Genetics - covers the history of mapping procedures as they were developed in classical genetics.

Mapping Our Genes

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Author :
Publisher :
ISBN 13 :
Total Pages : 228 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Mapping Our Genes by :

Download or read book Mapping Our Genes written by and published by . This book was released on 1988 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetic Mapping & DNA Sequencing

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Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (118 download)

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Book Synopsis Genetic Mapping & DNA Sequencing by : tp;waterman spped (ms)

Download or read book Genetic Mapping & DNA Sequencing written by tp;waterman spped (ms) and published by . This book was released on 1995 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mapping and Sequencing the Human Genome

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Author :
Publisher : National Academies Press
ISBN 13 : 9780309074629
Total Pages : 106 pages
Book Rating : 4.0/5 (746 download)

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Book Synopsis Mapping and Sequencing the Human Genome by : Committee on Mapping and Sequencing the Human Genome

Download or read book Mapping and Sequencing the Human Genome written by Committee on Mapping and Sequencing the Human Genome and published by National Academies Press. This book was released on 1988-01-15 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Genome Mapping and Genomics in Domestic Animals

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Publisher : Springer Science & Business Media
ISBN 13 : 3540738355
Total Pages : 289 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Genome Mapping and Genomics in Domestic Animals by : Noelle E. Cockett

Download or read book Genome Mapping and Genomics in Domestic Animals written by Noelle E. Cockett and published by Springer Science & Business Media. This book was released on 2008-10-31 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomics research on animals has generated huge databases and several new concepts and strategies, which are used to elucidate origin, evolution and phylogeny of species. Genetic and physical maps of genomes give details on chromosomal location, function, expression and regulation of genes. The series Genome Mapping and Genomics in Animals provides comprehensive and up-to-date reviews on genomic research on selected animal systems contributed by leading scientists from around the world. This volume offers information on gene mapping and genomics research in domesticated and farmed animals including cattle, water buffalo, sheep, deer, poultry, turkeys, rabbits, dogs and pigs. While the genome maps for some species are very limited, full genome sequences are available for cattle, chickens and dogs. Genomic research contributes to the identification of genetic regions that control the functionality and well-being of animals. Several farmed species are also used as models for biomedical studies.

Mapping Our Genes

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Publisher : Plume Books
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.:/5 (321 download)

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Book Synopsis Mapping Our Genes by : Lois Wingerson

Download or read book Mapping Our Genes written by Lois Wingerson and published by Plume Books. This book was released on 1991 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eye-opening and mind-expanding, "Mapping Our Genes" tells of the experts who are brightly hopeful about using genetic mapping and engineering as weapons in the war against the many incurable genetically inherited maladies.

Next-Generation Genome Sequencing

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Publisher : John Wiley & Sons
ISBN 13 : 3527644733
Total Pages : 281 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Next-Generation Genome Sequencing by : Michal Janitz

Download or read book Next-Generation Genome Sequencing written by Michal Janitz and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by leading experts from industry and academia, this first single comprehensive resource addresses recent developments in next generation DNA sequencing technology and their impact on genome research, drug discovery and health care. As such, it presents a detailed comparative analysis of commercially available platforms as well as insights into alternative, emerging sequencing techniques. In addition, the book not only covers the principles of DNA sequencing techniques but also social, ethical and commercial aspects, the concept of personalized medicine and a five-year perspective of DNA sequencing.

Mapping Humanity

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Publisher : BenBella Books
ISBN 13 : 1950665259
Total Pages : 249 pages
Book Rating : 4.9/5 (56 download)

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Book Synopsis Mapping Humanity by : Joshua Z. Rappoport

Download or read book Mapping Humanity written by Joshua Z. Rappoport and published by BenBella Books. This book was released on 2020-07-07 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A good companion for those with a science background interested in learning more about human genetics." —Booklist Thanks to the popularity of personal genetic testing services, it's now easier than ever to get information about our own unique DNA—but who does this information really benefit? And, as genome editing and gene therapy transform the healthcare landscape, what do we gain—and what might we give up in return? Inside each of your cells is the nucleus, a small structure that contains all of the genetic information encoded by the DNA inside, your genome. Not long ago, the first human genome was sequenced at a cost of nearly $3 billion; now, this same test can be done for about $1,000. This new accessibility of genome sequence information creates huge potential for advances in how we understand and treat disease, among other things. It also raises significant concerns regarding ethics and personal privacy. In Mapping Humanity: How Modern Genetics Is Changing Criminal Justice, Personalized Medicine, and Our Identities, cellular biology expert Joshua Z. Rappoport provides a detailed look at how the explosion in genetic information as a result of cutting-edge technologies is changing our lives and our world. Inside, discover: • An in-depth look at how your personal genome creates the unique individual that you are • How doctors are using DNA sequencing to identify the underlying genetic causes of disease • Why the field of gene therapy offers amazing potential for medical breakthroughs—and why it's taking so long • The fantastic potential—and troubling concerns—surrounding genome editing • The real impact—and validity—of popular personal genetic testing products, such as 23andMe • Details of how molecular biology and DNA are changing the criminal justice system • Facts you should know about Genetically Modified Organisms (GMOs) Throughout, in compelling, accessible prose, Rappoport explores the societal, ethical, and economic impacts of this new era. Offering a framework for balancing the potential risks and benefits of genetic information technologies and genetic engineering, Mapping Humanity is an indispensable guide to navigating the possibilities and perils of our gene-centric future.