The Applications of New Multi-Locus GWAS Methodologies in the Genetic Dissection of Complex Traits

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Publisher : Frontiers Media SA
ISBN 13 : 2889458342
Total Pages : 236 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis The Applications of New Multi-Locus GWAS Methodologies in the Genetic Dissection of Complex Traits by : Yuan-Ming Zhang

Download or read book The Applications of New Multi-Locus GWAS Methodologies in the Genetic Dissection of Complex Traits written by Yuan-Ming Zhang and published by Frontiers Media SA. This book was released on 2019-06-19 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome-Wide Association Studies (GWAS) are widely used in the genetic dissection of complex traits. Most existing methods are based on single-marker association in genome-wide scans with population structure and polygenic background controls. To control the false positive rate, the Bonferroni correction for multiple tests is frequently adopted. This stringent correction results in the exclusion of important loci, especially for GWAS in crop genetics. To address this issue, multi-locus GWAS methodologies have been recommended, i.e., FASTmrEMMA, ISIS EM-BLASSO, mrMLM, FASTmrMLM, pLARmEB, pKWmEB and FarmCPU. In this Research Topic, our purpose is to clarify some important issues in the application of multi-locus GWAS methods. Here we discuss the following subjects: First, we discuss the advantages of new multi-locus GWAS methods over the widely-used single-locus GWAS methods in the genetic dissection of complex traits, metabolites and gene expression levels. Secondly, large experiment error in the field measurement of phenotypic values for complex traits in crop genetics results in relatively large P-values in GWAS, indicating the existence of small number of significantly associated SNPs. To solve this issue, a less stringent P-value critical value is often adopted, i.e., 0.001, 0.0001 and 1/m (m is the number of markers). Although lowering the stringency with which an association is made could identify more hits, confidence in these hits would significantly drop. In this Research Topic we propose a new threshold of significant QTN (LOD=3.0 or P-value=2.0e-4) in multi-locus GWAS to balance high power and low false positive rate. Thirdly, heritability missing in GWAS is a common phenomenon, and a series of scientists have explained the reasons why the heritability is missing. In this Research Topic, we also add one additional reason and propose the joint use of several GWAS methodologies to capture more QTNs. Thus, overall estimated heritability would be increased. Finally, we discuss how to select and use these multi-locus GWAS methods.

Handbook of Maize

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Publisher : Springer Science & Business Media
ISBN 13 : 0387778632
Total Pages : 785 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Handbook of Maize by : Jeff L. Bennetzen

Download or read book Handbook of Maize written by Jeff L. Bennetzen and published by Springer Science & Business Media. This book was released on 2009-01-16 with total page 785 pages. Available in PDF, EPUB and Kindle. Book excerpt: Maize is one of the world’s highest value crops, with a multibillion dollar annual contribution to agriculture. The great adaptability and high yields available for maize as a food, feed and forage crop have led to its current production on over 140 million hectares worldwide, with acreage continuing to grow at the expense of other crops. In terms of tons of cereal grain produced worldwide, maize has been number one for many years. Moreover, maize is expanding its contribution to non-food uses, including as a major source of ethanol as a fuel additive or fuel alternative in the US. In addition, maize has been at the center of the transgenic plant controversy, serving as the first food crop with released transgenic varieties. By 2008, maize will have its genome sequence released, providing the sequence of the first average-size plant genome (the four plant genomes that are now sequenced come from unusually tiny genomes) and of the most complex genome sequenced from any organism. Among plant science researchers, maize has the second largest and most productive research community, trailing only the Arabidopsis community in scale and significance. At the applied research and commercial improvement levels, maize has no peers in agriculture, and consists of thousands of contributors worthwhile. A comprehensive book on the biology of maize has not been published. The "Handbook of Maize: the Genetics and Genomics" center on the past, present and future of maize as a model for plant science research and crop improvement. The books include brief, focused chapters from the foremost maize experts and feature a succinct collection of informative images representing the maize germplasm collection.

Plant Systems Biology

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Publisher : Springer Science & Business Media
ISBN 13 : 376437439X
Total Pages : 362 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis Plant Systems Biology by : Sacha Baginsky

Download or read book Plant Systems Biology written by Sacha Baginsky and published by Springer Science & Business Media. This book was released on 2007-06-25 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume aims to provide a timely view of the state-of-the-art in systems biology. The editors take the opportunity to define systems biology as they and the contributing authors see it, and this will lay the groundwork for future studies. The volume is well-suited to both students and researchers interested in the methods of systems biology. Although the focus is on plant systems biology, the proposed material could be suitably applied to any organism.

Genetics Abstracts

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Publisher :
ISBN 13 :
Total Pages : 844 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genetics Abstracts by :

Download or read book Genetics Abstracts written by and published by . This book was released on 1998 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drought Stress in Maize (Zea mays L.)

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Publisher : Springer
ISBN 13 : 3319254421
Total Pages : 79 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Drought Stress in Maize (Zea mays L.) by : Muhammad Aslam

Download or read book Drought Stress in Maize (Zea mays L.) written by Muhammad Aslam and published by Springer. This book was released on 2015-11-20 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on early germination, one of maize germplasm most important strategies for adapting to drought-induced stress. Some genotypes have the ability to adapt by either reducing water losses or by increasing water uptake. Drought tolerance is also an adaptive strategy that enables crop plants to maintain their normal physiological processes and deliver higher economical yield despite drought stress. Several processes are involved in conferring drought tolerance in maize: the accumulation of osmolytes or antioxidants, plant growth regulators, stress proteins and water channel proteins, transcription factors and signal transduction pathways. Drought is one of the most detrimental forms of abiotic stress around the world and seriously limits the productivity of agricultural crops. Maize, one of the leading cereal crops in the world, is sensitive to drought stress. Maize harvests are affected by drought stress at different growth stages in different regions. Numerous events in the life of maize crops can be affected by drought stress: germination potential, seedling growth, seedling stand establishment, overall growth and development, pollen and silk development, anthesis silking interval, pollination, and embryo, endosperm and kernel development. Though every maize genotype has the ability to avoid or withstand drought stress, there is a concrete need to improve the level of adaptability to drought stress to address the global issue of food security. The most common biological strategies for improving drought stress resistance include screening available maize germplasm for drought tolerance, conventional breeding strategies, and marker-assisted and genomic-assisted breeding and development of transgenic maize. As a comprehensive understanding of the effects of drought stress, adaptive strategies and potential breeding tools is the prerequisite for any sound breeding plan, this brief addresses these aspects.

Manual on MUTATION BREEDING THIRD EDITION

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Publisher : Food & Agriculture Org.
ISBN 13 : 9251305269
Total Pages : 319 pages
Book Rating : 4.2/5 (513 download)

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Book Synopsis Manual on MUTATION BREEDING THIRD EDITION by : Food and Agriculture Organization of the United Nations

Download or read book Manual on MUTATION BREEDING THIRD EDITION written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2018-10-09 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This paper provides guidelines for new high-throughput screening methods – both phenotypic and genotypic – to enable the detection of rare mutant traits, and reviews techniques for increasing the efficiency of crop mutation breeding.

Progress and Opportunities of Doubled Haploid Production

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Publisher : Springer Science & Business Media
ISBN 13 : 3319007327
Total Pages : 84 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Progress and Opportunities of Doubled Haploid Production by : Muhammad Asif

Download or read book Progress and Opportunities of Doubled Haploid Production written by Muhammad Asif and published by Springer Science & Business Media. This book was released on 2013-07-17 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deals with the historical perspectives and the current status of doubled haploid production along with its practical implications in basic and applied research. It highlights various haploid production methods with a comprehensive discussion on their pros and cons, bottlenecks, and embryogenic pathways. The review also describes in detail the results of molecular and genomic studies conducted to investigate the underlying principles of this spectacular technique that has changed the status of many species from recalcitrant to responsive over the last ninety years. ​

Plant Breeding in the Omics Era

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Publisher : Springer
ISBN 13 : 3319205323
Total Pages : 250 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Plant Breeding in the Omics Era by : Rodomiro Ortiz Ríos

Download or read book Plant Breeding in the Omics Era written by Rodomiro Ortiz Ríos and published by Springer. This book was released on 2015-09-16 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​The field of plant breeding has grown rapidly in the last decade with breakthrough research in genetics and genomics, inbred development, population improvement, hybrids, clones, self-pollinated crops, polyploidy, transgenic breeding and more. This book discusses the latest developments in all these areas but explores the next generation of needs and discoveries including omics beyond genomics, cultivar seeds and intellectual and property rights. This book is a leading-edge publication of the latest results and forecasts important areas of future needs and applications.​

CRISPR-Cas Systems

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Publisher : Springer Science & Business Media
ISBN 13 : 364234657X
Total Pages : 300 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis CRISPR-Cas Systems by : Rodolphe Barrangou

Download or read book CRISPR-Cas Systems written by Rodolphe Barrangou and published by Springer Science & Business Media. This book was released on 2012-12-13 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.

Peterson's Guide to Graduate Programs in the Biological Sciences 1997

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Publisher : Peterson Nelnet Company
ISBN 13 : 9781560796534
Total Pages : 2494 pages
Book Rating : 4.7/5 (965 download)

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Book Synopsis Peterson's Guide to Graduate Programs in the Biological Sciences 1997 by : Peterson's

Download or read book Peterson's Guide to Graduate Programs in the Biological Sciences 1997 written by Peterson's and published by Peterson Nelnet Company. This book was released on 1997-01-05 with total page 2494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Graduate students depend on this series and ask for it by name. Why? For over 30 years, it's been the only one-stop source that supplies all of their information needs. The new editions of this six-volume set contain the most comprehensive information available on more than 1,500 colleges offering over 31,000 master's, doctoral, and professional-degree programs in more than 350 disciplines. New for 1997 -- Non-degree-granting research centers, institutes, and training programs that are part of a graduate degree program. Five discipline-specific volumes detail entrance and program requirements, deadlines, costs, contacts, and special options, such as distance learning, for each program, if available. Each Guide features "The Graduate Adviser", which discusses entrance exams, financial aid, accreditation, and more. The only source that covers nearly 4,000 programs in such areas as oncology, conservation biology, pharmacology, and zoology.

Neglected and Underutilized Crops - Towards Nutritional Security and Sustainability

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Publisher : Springer Nature
ISBN 13 : 9811638764
Total Pages : 266 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Neglected and Underutilized Crops - Towards Nutritional Security and Sustainability by : Sajad Majeed Zargar

Download or read book Neglected and Underutilized Crops - Towards Nutritional Security and Sustainability written by Sajad Majeed Zargar and published by Springer Nature. This book was released on 2021-09-29 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers important topics on various neglected and underutilised crops (vegetables, cereals, fruit crops). It gives an overview of the potential, availability of genetic and genomic resources, and the future prospects of these food crops. The book presents different chapters on the importance of underutilised crops with respect to sustainable agriculture and describes the approaches that must be followed for improving the yield and production of these crops. It covers a wide range of food crops such as millet, buckwheat, underutilised spices, underutilised vegetables and underutilised fruit crops. It also provides insights on what smart foods are? And, whether these neglected crops qualify as smart foods? This up-to-date and informative book is meant for food scientists, geneticists, breeders and biotechnologists. It is of interest to students, researchers and course instructors in these fields.

Virus-Induced Gene Silencing

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Publisher : Humana Press
ISBN 13 : 9781627032773
Total Pages : 0 pages
Book Rating : 4.0/5 (327 download)

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Book Synopsis Virus-Induced Gene Silencing by : Annette Becker

Download or read book Virus-Induced Gene Silencing written by Annette Becker and published by Humana Press. This book was released on 2013-02-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants are amazing organisms to study, some are important sources for pharmaceuticals, and others can help to elucidate molecular mechanisms required for a plant’s development and its interactions with the biotic or abiotic environment. Functional genomics is vastly lagging behind the speed of genome sequencing as high-throughput gene function assays are difficult to design, specifically for non-model plants. Bioinformatics tools are useful for gene identification and annotation but are of limited value for predictions concerning gene functions as gene functions are uncovered best by experimental approaches. Virus-Induced-Gene-Silencing (VIGS) is an easy to use, fast, and reliable method to achieve down regulation of target gene expression. Virus-Induced Gene Silencing: Methods and Protocols provides detailed protocols for VIGS experiments in several plant species including model and non-model plants. Also included in this book are recently developed protocols for VIGS-derived microRNA production in the plant or protein over expression, as well as chapters devoted to summarizing the molecular mechanisms of VIGS action and the vector systems developed so far. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Virus-Induced Gene Silencing: Methods and Protocols serves as a valuable resource for researchers from diverse fields of plant biology interested in experimental approaches to analyzing gene functions.

Genetic and Genomic Resources of Grain Legume Improvement

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Publisher : Newnes
ISBN 13 : 0123984947
Total Pages : 322 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Genetic and Genomic Resources of Grain Legume Improvement by : Mohar Singh

Download or read book Genetic and Genomic Resources of Grain Legume Improvement written by Mohar Singh and published by Newnes. This book was released on 2013-07-18 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Grain legumes, including common-bean, chickpea, pigeonpea, pea, cowpea, lentil and others, form important constituents of global diets, both vegetarian and non-vegetarian. Despite this significant role, global production has increased only marginally in the past 50 years. The slow production growth, along with a rising human population and improved buying capacity has substantially reduced the per capita availability of food legumes. Changes in environmental climate have also had significant impact on production, creating a need to identify stable donors among genetic resources for environmentally robust genes and designing crops resilient to climate change. Genetic and Genomic Resources of Grain Legume Improvement is the first book to bring together the latest resources in plant genetics and genomics to facilitate the identification of specific germplasm, trait mapping and allele mining to more effectively develop biotic and abiotic-stress-resistant grains. This book will be an invaluable resource for researchers, crop biologists and students working with crop development. - Explores origin, distribution and diversity of grain legumes - Presents information on germplasm collection, evaluation and maintenance - Offers insight into pre-breeding/germplasm enhancement efforts - Integrates genomic and genetic resources in crop improvement - Internationally contributed work

Plant Cytogenetics, Third Edition

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Publisher : CRC Press
ISBN 13 : 1315356996
Total Pages : 544 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Plant Cytogenetics, Third Edition by : Ram J. Singh

Download or read book Plant Cytogenetics, Third Edition written by Ram J. Singh and published by CRC Press. This book was released on 2016-11-18 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytogenetics plays an important role in understanding the chromosomal and genetic architecture of plant species. Plant Cytogenetics, Third Edition follows the tradition of its predecessors presenting theoretical and practical aspects of plant cytogenetics. Chapters describe correct handling of plant chromosomes, methods in plant cytogenetics, cell division, reproduction methods, chromosome nomenclature, karyotype analysis, chromosomal aberrations, genome analysis, transgenic crops, and cytogenetics in plant breeding. This new edition begins with a brief introduction on the historical aspect of cytogenetics and flows directly into handling of plant chromosomes by classical and modern cytological techniques, classical Mendelian Genetics, brief description of cell division, and chromosome identification by karyotype analysis. The comprehension of cytogenetics is incomplete without information on the role of aneuploidy in associating a gene on a particular chromosome, and the book covers these methodologies as a primary topic. Covering classical to modern cytogenetics, the book presents to the reader the crucial role of cytogenetics in improving crops.

Wheat Improvement

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Publisher :
ISBN 13 :
Total Pages : 24 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Wheat Improvement by : Frank Azor Spragg

Download or read book Wheat Improvement written by Frank Azor Spragg and published by . This book was released on 1912 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Broadening the Genetic Base of Crop Production

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Publisher :
ISBN 13 :
Total Pages : 484 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Broadening the Genetic Base of Crop Production by : H. David Cooper

Download or read book Broadening the Genetic Base of Crop Production written by H. David Cooper and published by . This book was released on 2001 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the previously neglected interface between the conservation of plant genetic resources and their utilization. Only through utilization can the potential value of conserved genetic resources be realized. However, as this book shows, much conserved germplasm has to be subjected to long-term pre-breeding and genetic enhancement before it can be used in plant breeding programs.The authors explore the rationale and approaches for such pre-breeding efforts as the basis for broadening the genetic bases of crop production. Examples from a range of major food crops are presented and issues analyzed by leading authorities from around the world.

Molecular Advances in Insect Resistance of Field Crops

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Publisher : Springer Nature
ISBN 13 : 3030921522
Total Pages : 432 pages
Book Rating : 4.0/5 (39 download)

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Book Synopsis Molecular Advances in Insect Resistance of Field Crops by : Amarjit S Tanda

Download or read book Molecular Advances in Insect Resistance of Field Crops written by Amarjit S Tanda and published by Springer Nature. This book was released on 2022-05-03 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the understanding that tolerance to pest pressure increases with less crop stress, this book covers all aspects of the molecular mechanisms underlying insect resistance in field crops. Detailed descriptions, accompanied by numerous photographs and schematic drawings, are available for “hot topics” such as genetically engineered crops, crispr/cas9 system, insect pest resistance technology, host plant resistance, and other major breakthroughs. Specific case studies include, but not limit to, the use of insect resistant cultivars in IPMT programs, utilization of glucosinolate-myrosinase processes in oilseed crops, and role of genetic in rice breeding technology.