Genetic Alchemy

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Encoding Capital

Author : Rodney Loeppky
Publisher : Routledge
ISBN 13 : 1135471150
Total Pages : 256 pages
Book Rating : 4.1/5 (354 download)

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Book Synopsis Encoding Capital by : Rodney Loeppky

Download or read book Encoding Capital written by Rodney Loeppky and published by Routledge. This book was released on 2013-09-13 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the rapid changes in contemporary molecular biology, particularly genome sciences, and the manner in which they can be understood through the lens of political economy. Specifically, the work investigates the case of the United States-led Genome Project (HGP), in order to show that even large-scale basic science is closely bound up in the progression of capitalist social relations. The work has, in part, been motivated by the lack of rigorous analysis of the HGP. Most the existing literature tends to present either a chronological review of events surrounding the HGP or describe it thematically. In contrast, this book contributes to a needed discussion concerning the 'why and how' of the HGP emergence. It elucidates the features within capitalist social relations which have simultaneously enable the HGP and ensure its amenability to systemic demands. The work's most compelling elements are both historical and analytical. Historically, it places the HGP within the context of wider political, economic and social issues. Related to this, it puts forward an analytical, explanatory understanding of the project's emergence, making it a valuable tool for both political economists, science & society theorists, and even bioethicists.

Gene Jockeys

Author : Nicolas Rasmussen
Publisher : JHU Press
ISBN 13 : 1421413418
Total Pages : 260 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Gene Jockeys by : Nicolas Rasmussen

Download or read book Gene Jockeys written by Nicolas Rasmussen and published by JHU Press. This book was released on 2014-05-15 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientific scramble to discover the first generation of drugs created through genetic engineering. The biotech arena emerged in the 1970s and 1980s, when molecular biology, one of the fastest-moving areas of basic science in the twentieth century, met the business world. Gene Jockeys is a detailed study of the biotech projects that led to five of the first ten recombinant DNA drugs to be approved for medical use in the United States: human insulin, human growth hormone, alpha interferon, erythropoietin, and tissue plasminogen activator. Drawing on corporate documents obtained from patent litigation, as well as interviews with the ambitious biologists who called themselves gene jockeys, historian Nicolas Rasmussen chronicles the remarkable, and often secretive, work of the scientists who built a new domain between academia and the drug industry in the pursuit of intellectual rewards and big payouts. In contrast to some who critique the rise of biotechnology, Rasmussen contends that biotech was not a swindle, even if the public did pay a very high price for the development of what began as public scientific resources. Within the biotech enterprise, the work of corporate scientists went well beyond what biologists had already accomplished within universities, and it accelerated the medical use of the new drugs by several years. In his technically detailed and readable narrative, Rasmussen focuses on the visible and often heavy hands that construct and maintain the markets in public goods like science. He looks closely at how science follows money, and vice versa, as researchers respond to the pressures and potential rewards of commercially viable innovations. In biotechnology, many of those engaged in crafting markets for genetically engineered drugs were biologists themselves who were in fact trying to do science. This book captures that heady, fleeting moment when a biologist could expect to do great science through the private sector and be rewarded with both wealth and scientific acclaim.

As Gods

Author : Matthew Cobb
Publisher : Basic Books
ISBN 13 : 1541602846
Total Pages : 502 pages
Book Rating : 4.5/5 (416 download)

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Book Synopsis As Gods by : Matthew Cobb

Download or read book As Gods written by Matthew Cobb and published by Basic Books. This book was released on 2022-11-15 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thrilling and terrifying history of genetic engineering In 2018, scientists manipulated the DNA of human babies for the first time. As biologist and historian Matthew Cobb shows in As Gods, this achievement was one many scientists have feared from the start of the genetic age. Four times in the last fifty years, geneticists, frightened by their own technology, have called a temporary halt to their experiments. They ought to be frightened: Now we have powers that can target the extinction of pests, change our own genes, or create dangerous new versions of diseases in an attempt to prevent future pandemics. Both awe-inspiring and chilling, As Gods traces the history of genetic engineering, showing that this revolutionary technology is far too important to be left to the scientists. They have the power to change life itself, but should we trust them to keep their ingenuity from producing a hellish reality?

Genetic Alchemy

Author : Sheldon Krimsky
Publisher : MIT Press (MA)
ISBN 13 : 9780262110839
Total Pages : 445 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Genetic Alchemy by : Sheldon Krimsky

Download or read book Genetic Alchemy written by Sheldon Krimsky and published by MIT Press (MA). This book was released on 1982-01-01 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNS / Manipulation.

The Gene Wars

Author : Robert M. Cook-Deegan
Publisher : W. W. Norton & Company
ISBN 13 : 9780393313994
Total Pages : 420 pages
Book Rating : 4.3/5 (139 download)

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Book Synopsis The Gene Wars by : Robert M. Cook-Deegan

Download or read book The Gene Wars written by Robert M. Cook-Deegan and published by W. W. Norton & Company. This book was released on 1994 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cook-Deegan, a former director of the Biomedical Ethics Advisory Committee of the US Congress and an advisor to the National Center for Human Genome Research, gives a firsthand account of the struggle to launch the Human Genome Project. Using primary documents and interviews, Cook-Deegan explains scientific details, chronicles the origins of the project, covers the conflicts and partnerships between the organizations involved, and examines ethical, legal, and social issues of DNA research. Includes bandw photos. Annotation copyright by Book News, Inc., Portland, OR

Biotech

Author : Eric J. Vettel
Publisher : University of Pennsylvania Press
ISBN 13 : 0812203623
Total Pages : 291 pages
Book Rating : 4.8/5 (122 download)

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Book Synopsis Biotech by : Eric J. Vettel

Download or read book Biotech written by Eric J. Vettel and published by University of Pennsylvania Press. This book was released on 2013-03-01 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: The seemingly unlimited reach of powerful biotechnologies and the attendant growth of the multibillion-dollar industry have raised difficult questions about the scientific discoveries, political assumptions, and cultural patterns that gave rise to for-profit biological research. Given such extraordinary stakes, a history of the commercial biotechnology industry must inquire far beyond the predictable attention to scientists, discovery, and corporate sales. It must pursue how something so complex as the biotechnology industry was born, poised to become both a vanguard for contemporary world capitalism and a focal point for polemic ethical debate. In Biotech, Eric J. Vettel chronicles the story behind genetic engineering, recombinant DNA, cloning, and stem-cell research. It is a story about the meteoric rise of government support for scientific research during the Cold War, about activists and student protesters in the Vietnam era pressing for a new purpose in science, about politicians creating policy that alters the course of science, and also about the release of powerful entrepreneurial energies in universities and in venture capital that few realized existed. Most of all, it is a story about people—not just biologists but also followers and opponents who knew nothing about the biological sciences yet cared deeply about how biological research was done and how the resulting knowledge was used. Vettel weaves together these stories to illustrate how the biotechnology industry was born in the San Francisco Bay area, examining the anomalies, ironies, and paradoxes that contributed to its rise. Culled from oral histories, university records, and private corporate archives, including Cetus, the world's first biotechnology company, this compelling history shows how a cultural and political revolution in the 1960s resulted in a new scientific order: the practical application of biological knowledge supported by private investors expecting profitable returns eclipsed basic research supported by government agencies.

Genetics

Author : Thomas A. Shannon
Publisher : Sheed & Ward
ISBN 13 : 1461674964
Total Pages : 213 pages
Book Rating : 4.4/5 (616 download)

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Book Synopsis Genetics by : Thomas A. Shannon

Download or read book Genetics written by Thomas A. Shannon and published by Sheed & Ward. This book was released on 2005-01-20 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over a decade ago, the field of bioethics was established in response to the increased control over the design of living organisms afforded by both medical genetics and biotechnology. Since its introduction, bioethics has become established as an academic discipline with journals and professional societies, is covered regularly in the media, and affects people everyday around the globe. In response to the increasing need for information about medical genetics and biotechnology as well as the ethical issues these fields raise, Sheed & Ward proudly presents the Readings in Bioethics Series. Edited by Thomas A. Shannon, the series provides anthologies of critical essays and reflections by leading ethicists in four pivotal areas: reproductive technologies, genetic technologies, death and dying, and health care policy. The goal of this series is twofold: first, to provide a set of readers on thematic topics for introductory or survey courses in bioethics or for courses with a particular theme or time limitation. Second, each of the readers in this series is designed to help students focus more thoroughly and effectively on specific topics that flesh out the ethical issues at the core of bioethics. The series is also highly accessible to general readers interested in bioethics. This volume collects critical essays by leading scholars on issues in biotechnology, genetic counseling and the disabled, population screening, race-based gamete selection, stem cell research, reproductive freedom and preimplantation diagnosis, procreation for organ and tissue procurement, and other critical areas where moral and ethical dilemmas are emerging from new and existing practices, policy, and legislation.

The Visioneers

Author : W. Patrick McCray
Publisher : Princeton University Press
ISBN 13 : 0691176299
Total Pages : 366 pages
Book Rating : 4.6/5 (911 download)

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Book Synopsis The Visioneers by : W. Patrick McCray

Download or read book The Visioneers written by W. Patrick McCray and published by Princeton University Press. This book was released on 2017-06-06 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: The story of the visionary scientists who invented the future In 1969, Princeton physicist Gerard O'Neill began looking outward to space colonies as the new frontier for humanity's expansion. A decade later, Eric Drexler, an MIT-trained engineer, turned his attention to the molecular world as the place where society's future needs could be met using self-replicating nanoscale machines. These modern utopians predicted that their technologies could transform society as humans mastered the ability to create new worlds, undertook atomic-scale engineering, and, if truly successful, overcame their own biological limits. The Visioneers tells the story of how these scientists and the communities they fostered imagined, designed, and popularized speculative technologies such as space colonies and nanotechnologies. Patrick McCray traces how these visioneers blended countercultural ideals with hard science, entrepreneurship, libertarianism, and unbridled optimism about the future. He shows how they built networks that communicated their ideas to writers, politicians, and corporate leaders. But the visioneers were not immune to failure—or to the lures of profit, celebrity, and hype. O'Neill and Drexler faced difficulty funding their work and overcoming colleagues' skepticism, and saw their ideas co-opted and transformed by Timothy Leary, the scriptwriters of Star Trek, and many others. Ultimately, both men struggled to overcome stigma and ostracism as they tried to unshackle their visioneering from pejorative labels like "fringe" and "pseudoscience.? The Visioneers provides a balanced look at the successes and pitfalls they encountered. The book exposes the dangers of promotion—oversimplification, misuse, and misunderstanding—that can plague exploratory science. But above all, it highlights the importance of radical new ideas that inspire us to support cutting-edge research into tomorrow's technologies.

The Genetic Age

Author : Matthew Cobb
Publisher : Profile Books
ISBN 13 : 1782838031
Total Pages : 403 pages
Book Rating : 4.7/5 (828 download)

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Book Synopsis The Genetic Age by : Matthew Cobb

Download or read book The Genetic Age written by Matthew Cobb and published by Profile Books. This book was released on 2022-09-01 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: A TIMES ENVIRONMENT AND SCIENCE BOOK OF THE YEAR 2022 'The ideal guide to what is not just a fiendishly complex area of science but also an ethical minefield' Mail on Sunday A new gene editing technology, invented just seven years ago, has turned humanity into gods. Enabling us to manipulate the genes in virtually any organism with exquisite precision, CRISPR has given scientists a degree of control that was undreamt of even in science fiction. But CRISPR is just the latest, giant leap in a long journey to master genetics. The Genetic Age shows the astonishing, world-changing potential of the new genetics and the possible threats it poses, sifting between fantasy and the reality when it comes to both benefits and dangers. By placing each phase of discovery, anticipation and fear in the context of over fifty years of attempts to master the natural world, Matthew Cobb, the Baillie-Gifford-shortlisted author of The Idea of the Brain, weaves the stories of science, history and culture to shed new light on our future. With the powers now at our disposal, it is a future that is almost impossible to imagine - but it is one we will create ourselves.

Genetic Alchemy

Author : Sheldon Krimsky
Publisher : Mit Press
ISBN 13 : 9780262610384
Total Pages : 445 pages
Book Rating : 4.6/5 (13 download)

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Book Synopsis Genetic Alchemy by : Sheldon Krimsky

Download or read book Genetic Alchemy written by Sheldon Krimsky and published by Mit Press. This book was released on 1984-11-01 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Alchemy summarizes and clarifies the background of policy and ethical issues, the debates engendered by uncertain risks to researchers and the population at large, and the roles played by scientists involved in one of the most prominent and controversial new technologies, gene splicing. The author, Assistant Professor of Urban and Environmental Policy at Tufts University, brings to the topic his experience on the Cambridge Review Board as it considered the siting of a recombinant DNA research facility, and on the NIH's Recombinant DNA Advisory Committee.

The Uses of Life

Author : Robert Bud
Publisher : Cambridge University Press
ISBN 13 : 9780521476997
Total Pages : 324 pages
Book Rating : 4.4/5 (769 download)

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Book Synopsis The Uses of Life by : Robert Bud

Download or read book The Uses of Life written by Robert Bud and published by Cambridge University Press. This book was released on 1994-05-27 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book shows, for the first time, how modern biotechnology grew out of this century's hopes for a new relationship between biology and engineering. Long before recombinant DNA, these promised a new kind of technology. By exploring the rich and surprisingly overlooked complex of prophesies, industrial and scientific development and government programs, the book sheds new light on the expectations now held for biotechnology. A world-wide view, covering developments, not just in America but also in Europe and Japan, uncovers surprising links. This makes possible a coherent story to supersede the historical notes which have been available until now. This first history of biotechnology provides a readable and challenging account that will appeal to anyone interested in the development of this key component of modern industry.

Prometheus Reimagined

Author : Albert C. Lin
Publisher : University of Michigan Press
ISBN 13 : 0472904337
Total Pages : 255 pages
Book Rating : 4.4/5 (729 download)

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Book Synopsis Prometheus Reimagined by : Albert C. Lin

Download or read book Prometheus Reimagined written by Albert C. Lin and published by University of Michigan Press. This book was released on 2023-11-29 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technologies such as synthetic biology, nanotechnology, artificial intelligence, and geoengineering promise to address many of our most serious problems, yet they also bring environmental and health-related risks and uncertainties. Moreover, they can come to dominate global production systems and markets with very little public input or awareness. Existing governance institutions and processes do not adequately address the risks of new technologies, nor do they give much consideration to the concerns of persons affected by them. Instead of treating technology, health, and the environment as discrete issues, Albert C. Lin argues that laws must acknowledge their fundamental relationship, anticipating both future technological developments and their potential adverse effects. Laws should encourage international cooperation and the development of common global standards, while allowing for flexibility and reassessment.

Worse Than the Disease

Author : Diana Barbara Dutton
Publisher : Cambridge University Press
ISBN 13 : 9780521395571
Total Pages : 548 pages
Book Rating : 4.3/5 (955 download)

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Book Synopsis Worse Than the Disease by : Diana Barbara Dutton

Download or read book Worse Than the Disease written by Diana Barbara Dutton and published by Cambridge University Press. This book was released on 1992-05-29 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: The distance between medical and public priorities is exposed in four case studies that reveal the human choices governing scientific innnovation and explore the political, economic and social factors influencing those choices.

Genetic Explanations

Author : Sheldon Krimsky
Publisher : Harvard University Press
ISBN 13 : 0674067762
Total Pages : 383 pages
Book Rating : 4.6/5 (74 download)

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Book Synopsis Genetic Explanations by : Sheldon Krimsky

Download or read book Genetic Explanations written by Sheldon Krimsky and published by Harvard University Press. This book was released on 2013-02-26 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: No longer viewed by scientists as the cell’s fixed master molecule, DNA is a dynamic script that is ad-libbed at each stage of development. What our parents hand down to us is just the beginning. Genetic Explanations urges us to replace our faith in genetic determinism with scientific knowledge about genetic plasticity and epigenetic inheritance.

Making Genes, Making Waves

Author : Jon Beckwith
Publisher : Harvard University Press
ISBN 13 : 0674020677
Total Pages : 251 pages
Book Rating : 4.6/5 (74 download)

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Book Synopsis Making Genes, Making Waves by : Jon Beckwith

Download or read book Making Genes, Making Waves written by Jon Beckwith and published by Harvard University Press. This book was released on 2009-07-01 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1969, Jon Beckwith and his colleagues succeeded in isolating a gene from the chromosome of a living organism. Announcing this startling achievement at a press conference, Beckwith took the opportunity to issue a public warning about the dangers of genetic engineering. Jon Beckwith's book, the story of a scientific life on the front line, traces one remarkable man's dual commitment to scientific research and social responsibility over the course of a career spanning most of the postwar history of genetics and molecular biology. A thoroughly engrossing memoir that recounts Beckwith's halting steps toward scientific triumphs--among them, the discovery of the genetic element that turns genes on--as well as his emergence as a world-class political activist, Making Genes, Making Waves is also a compelling history of the major controversies in genetics over the last thirty years. Presenting the science in easily understandable terms, Beckwith describes the dramatic changes that transformed biology between the late 1950s and our day, the growth of the radical science movement in the 1970s, and the personalities involved throughout. He brings to light the differing styles of scientists as well as the different ways in which science is presented within the scientific community and to the public at large. Ranging from the travails of Robert Oppenheimer and the atomic bomb to the Human Genome Project and recent "Science Wars," Beckwith's book provides a sweeping view of science and its social context in the latter half of the twentieth century.

Cut-and-Paste Genetics

Author : Sahotra Sarkar
Publisher : Rowman & Littlefield
ISBN 13 : 1786614391
Total Pages : 225 pages
Book Rating : 4.7/5 (866 download)

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Book Synopsis Cut-and-Paste Genetics by : Sahotra Sarkar

Download or read book Cut-and-Paste Genetics written by Sahotra Sarkar and published by Rowman & Littlefield. This book was released on 2021-09-15 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of CRISPR/Cas9 technology has revolutionized gene editing. The Nobel prize for chemistry was awarded to Emmanuelle Charpentier and Jennifer Doudna, the scientists responsible for its discovery, in 2020 and it is considered the frontier of sophisticated medical science. This technology contains the promise that both gene therapy and eugenic control of human evolution is possible, even plausible, in our near future. This book looks at these developements in the context of the history of previous social and scientific attempts at genetic editing, and explores the policy and ethical challenges they raise. It presents the case for altering the human germ-line (which contains and controls hereditary genetic information) to eliminate a large number of genetic diseases controlled by a single or few genes, while pointing out that gene therapy is likely to be ineffective for diseases with more complex causes. In parallel it explores the possibility of genetic enhancement in a set of case studies. But it also argues that, in general, genetic enhancement is ethically problematic and should be approached with caution. Given the success of CRISPR/Cas9 gene editing, and the explosion of related techniques, in practice it would be virtually impossible to ban germ-line editing in our future. A more useful goal is to put regulation in place, with oversight that represents the interests of society. That, in turn, requires an informed public discussion of these issues, which is the intention of this book.

The Gene

Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
ISBN 13 : 1476733538
Total Pages : 624 pages
Book Rating : 4.4/5 (767 download)

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Book Synopsis The Gene by : Siddhartha Mukherjee

Download or read book The Gene written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2016-05-17 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).