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Gene Therapy And Cancer Research Progress
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Book Synopsis Gene Therapy and Cancer Research Progress by : Jessica L. Lewis
Download or read book Gene Therapy and Cancer Research Progress written by Jessica L. Lewis and published by Nova Publishers. This book was released on 2008 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genes, which are carried on chromosomes, are the basic physical and functional units of heredity. Genes are specific sequences of bases that encode instructions on how to make proteins. Although genes get a lot of attention, it's the proteins that perform most life functions and even make up the majority of cellular structures. When genes are altered so that the encoded proteins are unable to carry out their normal functions, genetic disorders can result. Gene therapy is an experimental treatment that involves introducing genetic material into a person's cells to fight disease. Gene therapy is being studied in clinical trials for many different types of cancer and for numerous other diseases. This new book presents the latest research in the field from around the world.
Book Synopsis Gene-Based Therapies for Cancer by : Jack A. Roth
Download or read book Gene-Based Therapies for Cancer written by Jack A. Roth and published by Springer Science & Business Media. This book was released on 2010-07-28 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer gene therapy is a novel therapy that targets the underlying genetic defects in the cancer cell. Progress in this field has been rapid and gene therapy promises to further extend personalized cancer treatment. In this volume leading experts have contributed their experience in developing gene therapies for a variety of cancers. Translational gene therapy approaches are emphasized. Chapters include discussions of specific gene delivery technologies as well as their application to various cancers with extensive discussions of ongoing clinical trials. This information should be useful to both students, fellows, and experienced scientists with an interest in this rapidly developing area.
Book Synopsis Recent Advances in Cancer Research and Therapy by : Xin-Yuan Liu
Download or read book Recent Advances in Cancer Research and Therapy written by Xin-Yuan Liu and published by Elsevier. This book was released on 2012-05-18 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super Interferon, HecI based and liposome based therapy, gene therapy, and p53 based cancer therapy. There is also a discussion of current cancer research in China including traditional Chinese medicine. Written by leading scientists in the field, this book provides an essential insight into the current state of cancer therapy and treatment. Includes a wide range of research areas including a focus on biotherapy and the development of novel cancer therapeutic strategies. Formatted for a broad audience including all working in researching cancer treatments and therapies. Discusses special traits and results of Chinese cancer research.
Book Synopsis Cancer Gene Therapy by Viral and Non-viral Vectors by : Malcolm Brenner
Download or read book Cancer Gene Therapy by Viral and Non-viral Vectors written by Malcolm Brenner and published by John Wiley & Sons. This book was released on 2014-02-25 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides expert, state-of-the-art insight into the current progress of viral and non-viral gene therapy Translational medicine has opened the gateway to the era of personalized or precision medicine. No longer a one-size-fits-all approach, the treatment of cancer is now based on an understanding of underlying biologic mechanisms and is increasingly being tailored to the molecular specificity of a tumor. This book provides a comprehensive overview of the pertinent molecular discoveries in the cancer field and explains how these are being used for gene-based cancer therapies. Designed as a volume in the Translational Oncology book series, Cancer Gene Therapy by Viral and Non-viral Vectors deals with the practice of gene-therapy, with reference to vectors for gene expression and gene transfer, as well as viral therapy. It covers the history and current and future applications of gene transfer in cancer, and provides expert insight on the progress of viral and non-viral gene therapy with regard to delivery system, vector design, potential therapeutic genes, and principles and regulations for cancer gene therapy. Presented in three parts, Cancer Gene Therapy by Viral and Non-viral Vectors covers: Delivery Systems • Translational Cancer Research: Gene Therapy by Viral and Non-viral Vectors • Retroviruses for Cancer Therapy • DNA Plasmids for Non-viral Gene Therapy of Cancer • Cancer Therapy with RNAi delivered by Non-viral Membrane/Core Nanoparticles Targeted Expression • Cancer Gene Therapy by Tissue-specific and Cancer-targeting Promptors • MicroRNAs as Drugs and Drug Targets in Cancer Principles of Clinical Trials in Gene Therapy • Regulatory issues for Manufacturers of Viral Vectors and Vector-transduced Cells for Phase I/II Trials • US Regulations Governing Clinical Trials in Gene Therapy • Remaining Obstacles to the Success of Cancer Gene Therapy Focusing on speeding the process in clinical cancer care by bringing therapies as quickly as possible from bench to bedside, Cancer Gene Therapy by Viral and Non-viral Vectors is an absolutely vital book for physicians, clinicians, researchers, and students involved in this area of medicine.
Book Synopsis Gene Therapy for Cancer by : Kelly K. Hunt
Download or read book Gene Therapy for Cancer written by Kelly K. Hunt and published by Springer Science & Business Media. This book was released on 2007-10-26 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three sections of this volume present currently available cancer gene therapy techniques. Part I describes the various aspects of gene delivery. In Part II, the contributors discuss strategies and targets for the treatment of cancer. Finally, in Part III, experts discuss the difficulties inherent in bringing gene therapy treatment for cancer to the clinic. This book will prove valuable as the volume of preclinical and clinical data continues to increase.
Book Synopsis Gene Therapy in the Treatment of Cancer by : Brian E. Huber
Download or read book Gene Therapy in the Treatment of Cancer written by Brian E. Huber and published by Cambridge University Press. This book was released on 1998-09-24 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews progress and considers future developments in the fast-evolving field of gene therapy in oncology.
Download or read book Horizons of Cancer Research written by and published by . This book was released on 1988 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Pathways to Progress by : National Cancer Institute (U.S.)
Download or read book Pathways to Progress written by National Cancer Institute (U.S.) and published by . This book was released on 1995 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :National Cancer Institute (U.S.). Prostate Cancer Progress Review Group Publisher : ISBN 13 : Total Pages :142 pages Book Rating :4.:/5 (327 download)
Book Synopsis Defeating Prostate Cancer by : National Cancer Institute (U.S.). Prostate Cancer Progress Review Group
Download or read book Defeating Prostate Cancer written by National Cancer Institute (U.S.). Prostate Cancer Progress Review Group and published by . This book was released on 1998 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Centers of the Cancer Universe by : Donald L. Trump
Download or read book Centers of the Cancer Universe written by Donald L. Trump and published by Rowman & Littlefield. This book was released on 2021-10-11 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: A 2022 Choice Reviews Outstanding Academic Title An important history of the development of cancer centers of excellence and the revolution in cancer treatment. In the 1960s a coalition of concerned citizens, scientists and politicians joined forces to convince the federal government to focus its efforts on conquering cancer. The National Cancer Act of 1971 resulted and was signed into law on December 23, 1971 by President Nixon. The national “War on Cancer,” was declared with some leaders naively arguing that the disease would be conquered by the nation’s bicentennial—a mere five years in the future. Over the next five decades scientific discoveries demonstrated the great complexity of what had formerly been thought of as a single disease – with the advent of the genetic characterization of cancers, it is now recognized that there are almost an infinite number of cancers as defined by their many genetic mutations. The National Cancer Act established the infrastructure for the designation of centers by the National Cancer Institute (NCI) and these centers have evolved into models of multidisciplinary, collaborative cancer research, treatment and prevention contributing to a reduction in cancer mortality and increase in quality of life and survival that has translated into more than 17 million cancer survivors in the United States in 2021. Centers of the Cancer Universe: A Half-Century of Progress Against Cancer tells the story of how cancer research was not front and center at most universities and research institutions before the National Cancer Act of 1971, and why many physicians were reluctant even to treat patients with cancer in the early 20th century. It follows the behind-the-scenes lobbying, resistance and negotiating that preceded signing the Act into law, and how the cancer centers of today came to fruition, and shaped how cancer research, clinical trials and treatment would be conducted.
Author :National Cancer Institute (U.S.). Lung Cancer Progress Review Group Publisher : ISBN 13 : Total Pages :84 pages Book Rating :4.:/5 (7 download)
Book Synopsis Report of the Lung Cancer Progress Review Group by : National Cancer Institute (U.S.). Lung Cancer Progress Review Group
Download or read book Report of the Lung Cancer Progress Review Group written by National Cancer Institute (U.S.). Lung Cancer Progress Review Group and published by . This book was released on 2001 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Transforming Clinical Research in the United States by : Institute of Medicine
Download or read book Transforming Clinical Research in the United States written by Institute of Medicine and published by National Academies Press. This book was released on 2010-10-22 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise.
Download or read book Advances in Cancer Research written by and published by Academic Press. This book was released on 1995-05-25 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: ADVANCES IN CANCER RESEARCH is a biannual publication that includes timely reviews on the most cutting-edge issues in cancer research. Volume 66 contains encompassing overviews of p53 and its role in both breast cancer and in the cell cycle. Approximately 50% of all human tumors involve mutations of the p53 gene, suggesting that proper understanding of its properties and mechanisms could offer real hope for finding successful clinical therapy. Other themes presented in Volume 66 include cyclins and cyclin-dependent kinases in the cell cycle. Approximately 50% of all human tumors involve mutations of the p53 gene, suggesting that proper understanding of its properties and mechanisms could offer real hope for finding sucessful clinical therapy. Other themes presented in Volume 66 include cyclins and cyclin-dependant kinases in the cell cycle: the molecular genetics of 11q23 chromosome translocations: the possible link between the aberrant expression of Scatter Factor and c-Met with AIDS Associated kaposi's Sarcoma, the use of Radiation Leukemia Virus to induce leukemogenesis, and the Adenovirus system as a model for the insertion of foreign DNA into mammalian genomes. Also of note in the "Foundations of cancer Research" section are articles by two prominent cancer researchers recollecting the ideas and paths taken in their lifelong work. Paradigms proposed in these reviews mark thoughtful progress toward preventative therapy in oncogenesis and gene therapy of cancer. They also cast light on the fact that the ideas presented in these chapters are only the tip of the iceburg in this complex and ever evolving field, and suggest many more to come in future volumes. Contains two Foundations in Cancer Research articles with personal accounts by prominent biologists on their careers in cancer research Presents overviews of the role of p53 in breast cancer and cell cycle regulation Describes the regulatory role of cyclins and cyclin dependent kinases in DNA replication and cell division Explains the puzzling link between HIV infection and Kaposis Sarcoma Includes models for retrovirus-induced tumorigenesis and foreign DNA insertion into mammalian genomes
Book Synopsis Recent Progress In Cancer Research by : Careen K. Tang
Download or read book Recent Progress In Cancer Research written by Careen K. Tang and published by . This book was released on 2007-01-01 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular signaling pathways are fundamental to normal cell processes such as cell cycle progression, growth, differentiation, and death. A delicate balance between activation and inhibitory signals must be maintained such that the normal cellular integrity is not altered. Cancer arises from a stepwise accumulation of genetic changes that liberate neoplastic cells from the homeostatic mechanisms which normally govern cell proliferation. Extensive evidence indicates that human cancers exhibit genetic alterations in multiple tumor suppressor genes and oncogenes. Signaling via proto-oncogenes has been associated with the malignant transformation, growth, and progression of many solid human tumors. The interaction of growth factors, cytokines, and hormones with specific membrane receptors triggers a cascade of intracellular biochemical signals, resulting in the activation and repression of various subsets of genes. The current goal in cancer therapy is to use our knowledge of the molecular alterations in a cancer cell to choose the most appropriate signal transduction inhibitor for an individual patient. Improvement in our understanding of the intrinsic aberrances found in cancer cells will enable the design of novel cancer treatments which specifically target these changes. Understanding the molecular events that occur during the multistep process of carcinogenesis will provide the imperative information necessary for battling this devastating disease. The review articles presented in this book cover a wide range of scientific topics related to the molecular mechanism of human cancer.
Book Synopsis The Nation's Progress in Cancer Research by : National Cancer Institute (U.S.)
Download or read book The Nation's Progress in Cancer Research written by National Cancer Institute (U.S.) and published by . This book was released on 2003 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Gene Therapy in the CNS – Progress and Prospects for Novel Therapies by : Casper René Gøtzsche
Download or read book Gene Therapy in the CNS – Progress and Prospects for Novel Therapies written by Casper René Gøtzsche and published by Frontiers Media SA. This book was released on 2021-12-21 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:
