Gene Mapping, Discovery, and Expression

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Publisher : Springer Science & Business Media
ISBN 13 : 1597450979
Total Pages : 335 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Gene Mapping, Discovery, and Expression by : Minou Bina

Download or read book Gene Mapping, Discovery, and Expression written by Minou Bina and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completion of the sequence of the human genome represents an unpar- leled achievement in the history of biology. The project has produced nearly complete, highly accurate, and comprehensive sequences of genomes of s- eral organisms including human, mouse, drosophila, and yeast. Furthermore, the development of high-throughput technologies has led to an explosion of projects to sequence the genomes of additional organisms including rat, chimp, dog, bee, chicken, and the list is expanding. The nearly completed draft of genomic sequences from numerous species has opened a new era of research in biology and in biomedical sciences. In keeping with the interdisciplinary nature of the new scientific era, the chapters in Gene Mapping, Discovery, and Expression: Methods and Protocols recapitulate the necessity of integration of experimental and computational tools for solving - portant research problems. The general underlying theme of this volume is DNA sequence-based technologies. At one level, the book highlights the importance of databases, genome-browsers, and web-based tools for data access and ana- sis. More specifically, sequencing projects routinely deposit their data in p- licly available databases including GenBank, at the National Center of Biotechnology (NCBI) in the United States; EMBL, maintained by the European Bioinformatics Institute; and DDBJ, the DNA Data Bank of Japan. Currently, several browsers offer facile access to numerous genomic DNA sequences for gene mapping and data retrieval.

Mapping and Sequencing the Human Genome

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Author :
Publisher : National Academies Press
ISBN 13 : 0309038405
Total Pages : 128 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Mapping and Sequencing the Human Genome by : National Research Council

Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Evolution of Translational Omics

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Publisher : National Academies Press
ISBN 13 : 0309224187
Total Pages : 354 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Evolution of Translational Omics by : Institute of Medicine

Download or read book Evolution of Translational Omics written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-13 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Analysing Gene Expression

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Publisher : John Wiley & Sons
ISBN 13 : 3527605339
Total Pages : 992 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Analysing Gene Expression by : Stefan Lorkowski

Download or read book Analysing Gene Expression written by Stefan Lorkowski and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book combines the experience of 225 experts on 900 pages. Scientists worldwide are currently overwhelmed by the ever-increasing number and diversity of genome projects. This handbook is your guide through the jungle of new methods and techniques available to analyse gene expression - the first to provide such a broad view of the measurement of mRNA and protein expression in vitro, in situ and even in vivo. Despite this broad approach, detail is sufficient for you to grasp the principles behind each method. In each case, the authors weigh up the advantages and disadvantages, paying particular attention to the automated, high-throughput processing demanded by the biotech industry. Completely up to date, the book covers such ground-breaking methods such as DNA microarrays, serial analysis of gene expression, differential display, and identification of open reading frame expressed sequence tags. All the methods and necessary equipment are presented visually in more than 300 mainly colour illustrations to assist their step-by-step reproduction in your laboratory. Each chapter is rounded off with its own set of extensive references that provide access to detailed experimental protocols. In short, the bible of analysing gene expression.

Principles of Biology

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Publisher :
ISBN 13 : 9781636350417
Total Pages : pages
Book Rating : 4.3/5 (54 download)

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Book Synopsis Principles of Biology by : Lisa Bartee

Download or read book Principles of Biology written by Lisa Bartee and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.

Computational Genomics with R

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Publisher : CRC Press
ISBN 13 : 1498781861
Total Pages : 463 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Computational Genomics with R by : Altuna Akalin

Download or read book Computational Genomics with R written by Altuna Akalin and published by CRC Press. This book was released on 2020-12-16 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.

Microarrays

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Publisher : Springer Science & Business Media
ISBN 13 : 1588295893
Total Pages : 923 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis Microarrays by : Jang B. Rampal

Download or read book Microarrays written by Jang B. Rampal and published by Springer Science & Business Media. This book was released on 2007-07-27 with total page 923 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microarray Technology, Volumes 1 and 2, present information in designing and fabricating arrays and binding studies with biological analytes while providing the reader with a broad description of microarray technology tools and their potential applications. The first volume deals with methods and protocols for the preparation of microarrays. The second volume details applications and data analysis, which is important in analyzing the enormous data coming out of microarray experiments. Among the topics discussed in Volume 1: Synthesis Methods, are matrices in the synthesis of microarrays, array optimization processes, array-based comparative genomic hybridization, 60-mer oligonucleotide probes, bifunctional reagents NTMTA and NTPAC, and high density arrays using digital microarray synthesis platforms. Other topics include multiplex ligation-dependent probe amplification (MLPA), hybridization conditions in situ-synthesized oligo arrays, peptide arrays, high density replication tools (HDRT), protocols for the quantification of oligo hybridization, glyco-bead arrays, and an investigation into the emerging nano technology. Microarray Technology, Volumes 1 and 2, provide ample information to all levels of scientists from novice to those intimately familiar with array technology.

Protocols for Nucleic Acid Analysis by Nonradioactive Probes

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Publisher : Springer Science & Business Media
ISBN 13 : 1597452297
Total Pages : 318 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Protocols for Nucleic Acid Analysis by Nonradioactive Probes by : Elena Hilario

Download or read book Protocols for Nucleic Acid Analysis by Nonradioactive Probes written by Elena Hilario and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protocols for Nucleic Acid Analysis by Non-radioactive Probes, Second Edition provides a firm background on the basic preparative protocols required for the analysis of nucleic acids by nonradioactive methods. Presenting the methodologies using amazing new applications, this volume offers guide chapters on nucleic acid extractions, preparation of nucleic acid blots, and labeling of nucleic acids with nonradioactive haptens. New fluorescent techniques such as Real Time PCR and microarrays are also included, allowing users to get a nonradioactive protocol implemented in the laboratory with minimum adaptation required and fastest time to results. The protocols follow the successful Methods in Molecular BiologyTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

An Omics Perspective on Cancer Research

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Publisher : Springer Science & Business Media
ISBN 13 : 9048126754
Total Pages : 269 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis An Omics Perspective on Cancer Research by : William C.S. Cho

Download or read book An Omics Perspective on Cancer Research written by William C.S. Cho and published by Springer Science & Business Media. This book was released on 2010-04-07 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Omics is an emerging and exciting area in the field of science and medicine. Numerous promising developments have been elucidated using omics (including genomics, transcriptomics, epigenomics, proteomics, metabolomics, interactomics, cytomics and bioinformatics) in cancer research. The development of high-throughput technologies that permit the solution of deciphering cancer from higher dimensionality will provide a knowledge base which changes the face of cancer understanding and therapeutics. This is the first book to provide such a comprehensive coverage of a rapidly evolving area written by leading experts in the field of omics. It complies and details cutting-edge cancer research that covers the broad advances in the field and its application from cancer-associated gene discovery to drug target validation. It also highlights the potential of using integration approach for cancer research. This unique and timely book provides a thorough overview of developing omics, which will appeal to anyone involved in cancer research. It will be a useful reference book for graduate students of different subjects (medicine, biology, engineering, etc) and senior scientists interested in the fascinating area of advanced technologies in cancer research. Readership: This is a precious book for all types of readers – cancer researchers, oncologists, pathologists, biologists, clinical chemists, pharmacologists, pharmaceutical specialists, biostatisticians, and bioinformaticists who want to expand their knowledge in cancer research.

Application of New Genetic Technologies to Animal Breeding

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Publisher : CSIRO PUBLISHING
ISBN 13 : 0643098534
Total Pages : 450 pages
Book Rating : 4.6/5 (43 download)

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Book Synopsis Application of New Genetic Technologies to Animal Breeding by : Association for the Advancement of Animal Breeding and Genetics,

Download or read book Application of New Genetic Technologies to Animal Breeding written by Association for the Advancement of Animal Breeding and Genetics, and published by CSIRO PUBLISHING. This book was released on 2005-09-01 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 16th Biennial Conference of the Association for the Advancement of Animal Breeding and Genetics (AAABG) gathers together scientists, extension workers, producers and industry personnel to review developments in the application of new technologies to animal breeding. Conference presentations include 30 invited reviews and papers, and 95 contributed papers. All papers are peer-reviewed, and cover session topics that focus on genetic evaluation systems, gene expression profiling, identification and manipulation of quantitative trait loci, progress in applied programs and advanced statistical and computing techniques. Industry applications are discussed for improvement in production, health and reproduction of domestic livestock, aquaculture species and even crocodiles and ostriches. Institutions and industries in Australia, New Zealand, USA, South Africa, South-East Asia and Japan are represented with significant participation of major Cooperative Research Centres. These proceedings contain the full text of all contributed papers and summaries of the invited reviews which are published separately in the Australian Journal of Experimental Agriculture.

Application of New Genetic Technologies to Animal Breeding

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Publisher : CSIRO PUBLISHING
ISBN 13 : 064309234X
Total Pages : 451 pages
Book Rating : 4.6/5 (43 download)

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Book Synopsis Application of New Genetic Technologies to Animal Breeding by : Association for the Advancement of Animal Breeding and Genetics. Conference

Download or read book Application of New Genetic Technologies to Animal Breeding written by Association for the Advancement of Animal Breeding and Genetics. Conference and published by CSIRO PUBLISHING. This book was released on 2005 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Association for the Advancement of Animal Breeding and Genetics Inc. is a professional organisation based in Australia and New Zealand for livestock scientists, breeders, educators, students and industry service providers.

Arabidopsis Protocols, 2nd Edition

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Publisher : Springer Science & Business Media
ISBN 13 : 1597450030
Total Pages : 461 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Arabidopsis Protocols, 2nd Edition by : Julio Salinas

Download or read book Arabidopsis Protocols, 2nd Edition written by Julio Salinas and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: For several decades, Arabidopsis thaliana has been the organism of choice in the laboratories of many plant geneticists, physiologists, developmental biologists, and biochemists around the world. During this time, a huge amount of knowledge has been acquired on the biology of this plant species, which has resulted in the development of molecular tools that account for much more efficient research. The significance that Arabidopsis would attain in biological research may have been difficult to foresee in the 1980s, when its use in the laboratory started. In the meantime, it has become the model plant organism, much the same way as Drosophila, Caenorhabditis, or mouse have for animal systems. Today, it is difficult to envision research at the cutting edge of plant biology without the use of Arabidopsis. Since the first edition of Arabidopsis Protocols appeared, new developments have fostered an impressive advance in plant biology that prompted us to prepare Arabidopsis Protocols, Second Edition. Completion of the Arabidopsis genome sequence offered for the first time the opportunity to have in hand all of the genetic information required for studying plant function. In addition, the development of whole systems approaches that allow global analysis of gene expression and protein and metabolite dynamics has encouraged scientists to explore new scenarios that are extending the limits of our knowledge.

WAAP Book of the year 2003

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Publisher : BRILL
ISBN 13 : 908686533X
Total Pages : 331 pages
Book Rating : 4.0/5 (868 download)

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Book Synopsis WAAP Book of the year 2003 by : A. Rosati

Download or read book WAAP Book of the year 2003 written by A. Rosati and published by BRILL. This book was released on 2023-08-28 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: The World Association for Animal Production produces this book that is a reference tool for the animal scientific community and for policy makers worldwide. Sixty authors from the six continents contributed with thirty outstanding manuscripts. This volume is the first of a series that will be produced every year. The objective of this project is to establish a reference volume for livestock system and research development, for the use of international organizations, research institutes, policy makers and animal industries, worldwide. This book is particularly interesting for those wanting to get a deeper knowledge on the ""state of the art"" of livestock systems in the six continents. This aspect is illustrated in the first section of the volume, while the second section describes the development of research activities in nineteen specific fields of animal science. Furthermore, the readers will certainly be interested by reading the ""contemporary issues"" manuscripts belonging to the third section. The articles of this section were selected to accomplish the most ""urgent"" topics in animal industry. The volume is also completed with relevant statistics, furnishing information and data in a homogenous and easy to read structure. The changes that have happened in animal industries in the last decades are clearly illustrated in tables and graphics. These data, together with the interpretation of the articles of the previous sections, will render easier the prediction of future scenarios. The World Association for Animal Production produces this book that is a reference tool for the animal scientific community and for policy makers worldwide. Sixty authors from the six continents contributed with thirty outstanding manuscripts.

Genomics of Tropical Crop Plants

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Publisher : Springer Science & Business Media
ISBN 13 : 0387712194
Total Pages : 592 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Genomics of Tropical Crop Plants by : Paul H. Moore

Download or read book Genomics of Tropical Crop Plants written by Paul H. Moore and published by Springer Science & Business Media. This book was released on 2008-01-03 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: For a long time there has been a critical need for a book to assess the genomics of tropical plant species. At last, here it is. This brilliant book covers recent progress on genome research in tropical crop plants, including the development of molecular markers, and many more subjects. The first section provides information on crops relevant to tropical agriculture. The book then moves on to lay out summaries of genomic research for the most important tropical crop plant species.

Physiology and Biotechnology Integration for Plant Breeding

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Publisher : CRC Press
ISBN 13 : 9780203022030
Total Pages : 654 pages
Book Rating : 4.0/5 (22 download)

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Book Synopsis Physiology and Biotechnology Integration for Plant Breeding by : Henry T. Nguyen

Download or read book Physiology and Biotechnology Integration for Plant Breeding written by Henry T. Nguyen and published by CRC Press. This book was released on 2004-01-14 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global demand for wheat, rice, corn, and other essential grains is expected to steadily rise over the next twenty years. Meeting this demand by increasing production through increased land use is not very likely; and while better crop management may make a marginal difference, most agriculture experts agree that this anticipated deficit must be m

Glossary of Biotechnology & Agrobiotechnology Terms

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Publisher : CRC Press
ISBN 13 : 1315350793
Total Pages : 1183 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Glossary of Biotechnology & Agrobiotechnology Terms by : Kimball Nill

Download or read book Glossary of Biotechnology & Agrobiotechnology Terms written by Kimball Nill and published by CRC Press. This book was released on 2016-09-15 with total page 1183 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 5th edition of Glossary of Biotechnology and Agrobiotechnology Terms will be a significant expansion of the previous 4th edition. In the past decade, many new terms have been introduced due to the appearance and application of new crop plant breeding methods as well as technical advances in genetics, molecular biology, cell biology and agricultural research. The terms associated with important new technologies have been added to this new edition including terms related to Zinc Finger Proteins, Transcription Activator-Like Effectors (TALEs), TALE Nucleases, Genome Editing, CRISPR/Cas 9 Gene-editing Systems, Oligonucleortide-mediated Mutagenesis, and RNA Interference, as well as hundreds of others. The 5th edition, like previous editions, will be useful for regulators of agricultural biotechnology around the world, customers, biotech patent officials, venture capitalists, and agbiotech company executives, as well as biopharmaceutical industries and academics.

The Genetic Basis of Sleep and Sleep Disorders

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Publisher : Cambridge University Press
ISBN 13 : 1107041252
Total Pages : 434 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis The Genetic Basis of Sleep and Sleep Disorders by : Paul Shaw

Download or read book The Genetic Basis of Sleep and Sleep Disorders written by Paul Shaw and published by Cambridge University Press. This book was released on 2013-10-24 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive and up-to-date book to cover genetics and genetic techniques in the study of sleep and sleep disorders.