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Author : Lester Goldstein
Publisher :
ISBN 13 :
Total Pages : 522 pages
Book Rating : 4.3/5 (121 download)
Download or read book Gene Expression, Translation and the Behavior of Proteins written by Lester Goldstein and published by . This book was released on 1980 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Biology A Comprehensive Treatise V4 ...
Author : David M. Prescott
Publisher : Elsevier
ISBN 13 : 0323147623
Total Pages : 511 pages
Book Rating : 4.3/5 (231 download)
Download or read book Cell Biology A Comprehensive Treatise V4 written by David M. Prescott and published by Elsevier. This book was released on 2012-12-02 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Biology, A Comprehensive Treatise, Volume 4: Gene Expression: Translation and the Behavior of Proteins discusses the translation of genetic information into proteins. It also explains the activities and behaviors of proteins, which is the final stage of gene expression. This book opens with a discussion of the components and mechanism of the translational machinery – their structures, biogenesis, and cellular levels. It then explains the protein synthesis, wherein each chapter focuses on one aspect of the detailed process. Other topics covered in this book are the structure and function of cytoplasmic ribonucleoprotein complexes and the proteolytic cleavage in the posttranslational processing of proteins. This text also covers the regulation of enzyme activity and the movement of material between nucleus and cytoplasm. The last three chapters are more in-depth discussions on protein synthesis, intracellular transport, regulation, and secretion. As with the other volumes of this book series, readers will definitely benefit from the vast information provided in this book regarding protein, its activities, behaviors, and synthesis.
Author : David M. Prescott
Publisher :
ISBN 13 :
Total Pages : 518 pages
Book Rating : 4.:/5 (31 download)
Download or read book Cell Biology: Gene expression: translation and the behavior of proteins written by David M. Prescott and published by . This book was released on 1980 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lester Goldstein
Publisher :
ISBN 13 : 9780122895043
Total Pages : 516 pages
Book Rating : 4.8/5 (95 download)
Download or read book Gene Expression, Translation and the Behavior of Proteins written by Lester Goldstein and published by . This book was released on 1980 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Biology A Comprehensive Treatise V4 ...
Author : David M. Prescott
Publisher :
ISBN 13 : 9780122895043
Total Pages : pages
Book Rating : 4.8/5 (95 download)
Download or read book Cell Biology written by David M. Prescott and published by . This book was released on 1977 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lester Goldstein
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (929 download)
Download or read book Cell Biology written by Lester Goldstein and published by . This book was released on 1977 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : J. Ilan
Publisher : Springer Science & Business Media
ISBN 13 : 1461528941
Total Pages : 508 pages
Book Rating : 4.4/5 (615 download)
Download or read book Translational Regulation of Gene Expression 2 written by J. Ilan and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, which results from the dramatic increase in interest in the control mechanism employed in gene expression and the importance of the regulated proteins, presents new information not covered in Translational Regulation of Gene Expression, which was published in 1987. It is not a revision of the earlier book but, rather, an extension of that volume witl, special emphasis on mecha nIsm. As the reader will discover, there is enormous diversity in the systems employing genes for translational regulation in order to regulate the appearance of the final product-the protein. Thus, we find that important proteins such as protooncogenes, growth factors, stress proteins, cytokines, lymphokines, iron storage and iron-uptake proteins, and a panorama of prokaryotic proteins, as well as eukaryotic viral proteins, are translationally regulated. Since for some gene products the degree of control is greater by a few orders of magnitude than their transcription, we can state that for these genes, at least, the expression is translationall y controlled. Translational regulation of gene expression in eukaryotes has emerged in the last few years as a major research field. The present book describes mechanisms of translational regulation in bacteria, yeast, and eukaryotic viruses, as well as in eukaryotic genes. In this book we try to provide in-depth coverage by including important examples from each group rather than systematically including all additional systems not described in the previous volume.
Author : Lester Goldstein
Publisher :
ISBN 13 : 9780122895043
Total Pages : 520 pages
Book Rating : 4.8/5 (95 download)
Download or read book Gene Expression, Translation and the Behavior of Proteins written by Lester Goldstein and published by . This book was released on 1980 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Biology A Comprehensive Treatise V4 ...
Author : Nahum Sonenberg
Publisher : CSHL Press
ISBN 13 : 9780879696184
Total Pages : 1034 pages
Book Rating : 4.6/5 (961 download)
Download or read book Translational Control of Gene Expression written by Nahum Sonenberg and published by CSHL Press. This book was released on 2001 with total page 1034 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the 1996 publication of Translational Control, there has been fresh interest in protein synthesis and recognition of the key role of translation control mechanisms in regulating gene expression. This new monograph updates and expands the scope of the earlier book but it also takes a fresh look at the field. In a new format, the first eight chapters provide broad overviews, while each of the additional twenty-eight has a focus on a research topic of more specific interest. The result is a thoroughly up-to-date account of initiation, elongation, and termination of translation, control mechanisms in development in response to extracellular stimuli, and the effects on the translation machinery of virus infection and disease. This book is essential reading for students entering the field and an invaluable resource for investigators of gene expression and its control.
Author : Marianne Grunberg-Manago
Publisher : Elsevier
ISBN 13 : 0444601244
Total Pages : 537 pages
Book Rating : 4.4/5 (446 download)
Download or read book Interaction of Translational and Transcriptional Controls in the Regulation of Gene Expression written by Marianne Grunberg-Manago and published by Elsevier. This book was released on 2012-12-02 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interaction of Translational and Transcriptional Controls in the Regulation of Gene Expression presents the proceedings of the Fogarty International Conference on Translational/Transcriptional Regulation of Gene Expression, held at the National Institutes of Health in Bethesda, Maryland, on April 7-9, 1982. Speakers discussed the molecular strategies at work during the modulation of gene expression following transcriptional initiation. They also discussed recent developments in a number of key areas in which transcriptional and translational components interact. Organized into five sections encompassing 36 chapters, this volume explores both prokaryotic and eukaryotic systems, as well as structure-function correlations. It begins with an overview of translational/transcriptional controls in prokaryotes, the regulation of gene expression by transcription termination and RNA processing, and the structure and expression of initiation factor genes. It then examines the effect of the codon context on translational fidelity, including mistranslation of messenger RNA; protein synthesis for the construction of cell architecture; regulation of initiation factor activity; and translational regulation in cells. This book is a valuable resource for Fogarty International Scholars who want to broaden their knowledge and contribute their expertise to the National Institutes of Health community.
Author : Eric Jan
Publisher : Biota Publishing
ISBN 13 : 1615046313
Total Pages : 106 pages
Book Rating : 4.6/5 (15 download)
Download or read book Protein Translation written by Eric Jan and published by Biota Publishing. This book was released on 2014-05-01 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein synthesis is a fundamental aspect of gene expression across kingdoms. The regulation of translation is important for many biological processes including cell fate determination, development, and growth and is especially crucial to maintain cellular homeostasis during cellular stress and virus infection. Misregulation of protein translation can contribute to diseases such as diabetes, cancer, and neurodegenerative diseases. In this chapter, we highlight the basic understanding of eukaryotic translation and the major regulations that control biological events. We focus on signaling pathways that regulate overall protein synthesis and also mechanisms that control translation of specific mRNAs such as cis-acting elements within the 5' and 3 untranslated regions (UTR). Understanding these mechanisms provide insights into the fundamental gene regulations that may provide new targets for combating disease and virus infections.
Author : J. Ilan
Publisher : Springer Science & Business Media
ISBN 13 : 1468453653
Total Pages : 495 pages
Book Rating : 4.4/5 (684 download)
Download or read book Translational Regulation of Gene Expression written by J. Ilan and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Assen Marintchev
Publisher : Academic Press
ISBN 13 : 0123864976
Total Pages : 267 pages
Book Rating : 4.1/5 (238 download)
Download or read book Fidelity and Quality Control in Gene Expression written by Assen Marintchev and published by Academic Press. This book was released on 2012-01-27 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this volume is to provide a comprehensive mechanistic and quantitative view of the processes that mediate or influence the quality control in translation. In addition to discussing processes with direct contribution to translation fidelity, such as aminoacylation of tRNAs and translation elongation itself, special attention is given to other processes with impact on quality control: detection and elimination of defective mRNAs, recycling and translation re-initiation, mRNA editing, and translational recoding through programmed frame-shifting. Provides a comprehensive mechanistic and quantitative view of the processes that mediate or influence the quality control in translation Special attention is given to other processes with impact on quality control: detection and elimination of defective mRNAs, recycling and translation re-initiation, mRNA editing, and translational recoding through programmed frame-shifting
Author : P.A. Baeuerle
Publisher : Springer Science & Business Media
ISBN 13 : 1468468405
Total Pages : 294 pages
Book Rating : 4.4/5 (684 download)
Download or read book Inducible Gene Expression, Volume 1 written by P.A. Baeuerle and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells have evolved multiple strategies to adapt the composition and quality of their protein equipment to needs imposed by changes in intra- and extracellular conditions. The appearance of pro teins transmit ting novel functional properties to cells can be controlled at a transcrip tional, posttranscriptional, translational or posttranslational level. Extensive research over the past 15 years has shown that transcriptional regulation is used as the predominant strategy to control the production of new proteins in response to extracellular stimuli. At the level of gene transcription, the initiation ofmRNA synthesis is used most frequently to govern gene expression. The key elements controlling transcription initiation in eukaryotes are activator proteins (transactivators) that bind in a sequence-specific manner to short DNA sequences in the of genes. The activator binding sites are elements of larger proximity control units, ca lied promoters and enhancers, which bind many distinct proteins. These may synergize or negatively cooperate with the activators. The do novo binding of an activator to DNA or, if already bound to DNA, its functional activation is what ultimately turns on a high-level expression of genes. The activity of transactivators is controlled by signalling pathways and, in some cases, transactivators actively partici pate in signal transduction by moving from the cytoplasm into the nuc1eus. In this first volume of Inducible Gene Expression, leading scientists in the field review six eukaryotic transactivators that allow cells to respond to various extracellular stimuli by the expression of new proteins.
Author : Greco Hernández
Publisher : Springer
ISBN 13 : 3319394681
Total Pages : 564 pages
Book Rating : 4.3/5 (193 download)
Download or read book Evolution of the Protein Synthesis Machinery and Its Regulation written by Greco Hernández and published by Springer. This book was released on 2016-08-10 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: The “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the origins and evolution of the protein synthetic machinery.
Author :
Publisher : Academic Press
ISBN 13 : 0080889662
Total Pages : 420 pages
Book Rating : 4.0/5 (88 download)
Download or read book Translation Initiation: Extract Systems and Molecular Genetics written by and published by Academic Press. This book was released on 2007-10-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over fifty years the Methods in Enzymology series has been the critically aclaimed laboratory standard and one of the most respected publications in the field of biochemistry. The highly relevant material makes it an essential publication for researchers in all fields of life and related sciences. This volume, the first of three on the topic of Translation Initiation includes articles written by leaders in the field.
