Gene Amplification in Mammalian Cells

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Publisher : CRC Press
ISBN 13 : 1000104885
Total Pages : 576 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Gene Amplification in Mammalian Cells by : Rodney E. Kellems

Download or read book Gene Amplification in Mammalian Cells written by Rodney E. Kellems and published by CRC Press. This book was released on 2020-08-26 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serves as a comprehensive review to the substantial impact of gene amplification in molecular biology, genetic engineering and medical science. The book covers the mechanism of gene amplification, organization and structure of amplified genes.

Gene Amplification in Mammalian Cells

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Author :
Publisher : CRC Press
ISBN 13 : 9780367402662
Total Pages : 568 pages
Book Rating : 4.4/5 (26 download)

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Book Synopsis Gene Amplification in Mammalian Cells by : Rodney E. Kellems

Download or read book Gene Amplification in Mammalian Cells written by Rodney E. Kellems and published by CRC Press. This book was released on 2019-10-17 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serves as a comprehensive review to the substantial impact of gene amplification in molecular biology, genetic engineering and medical science. The book covers the mechanism of gene amplification, organization and structure of amplified genes.

Effects of Gene Amplification on the Growth and Productivity of Mammalian Cells

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (6 download)

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Book Synopsis Effects of Gene Amplification on the Growth and Productivity of Mammalian Cells by : Nandini Cossons

Download or read book Effects of Gene Amplification on the Growth and Productivity of Mammalian Cells written by Nandini Cossons and published by . This book was released on 1992 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gene Transfer Vectors for Mammalian Cells

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Publisher :
ISBN 13 :
Total Pages : 188 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Gene Transfer Vectors for Mammalian Cells by : Jeffrey H. Miller

Download or read book Gene Transfer Vectors for Mammalian Cells written by Jeffrey H. Miller and published by . This book was released on 1987 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Genetics of Mammalian Cells

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Author :
Publisher : Free Press
ISBN 13 :
Total Pages : 424 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Genetics of Mammalian Cells by : George M. Malacinski

Download or read book Molecular Genetics of Mammalian Cells written by George M. Malacinski and published by Free Press. This book was released on 1986 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Effect of Chromosomal Position on the Mode and Frequency of Gene Amplification in Mammalian Cells

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Publisher :
ISBN 13 :
Total Pages : 334 pages
Book Rating : 4.:/5 (246 download)

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Book Synopsis Effect of Chromosomal Position on the Mode and Frequency of Gene Amplification in Mammalian Cells by : Bradford Terpening Brinton

Download or read book Effect of Chromosomal Position on the Mode and Frequency of Gene Amplification in Mammalian Cells written by Bradford Terpening Brinton and published by . This book was released on 1991 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Characterization of the Initial Products of Mammalian Gene Amplification and the Mechanisms of Their Formation

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Publisher :
ISBN 13 :
Total Pages : 418 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Characterization of the Initial Products of Mammalian Gene Amplification and the Mechanisms of Their Formation by : Joseph C. Ruiz

Download or read book Characterization of the Initial Products of Mammalian Gene Amplification and the Mechanisms of Their Formation written by Joseph C. Ruiz and published by . This book was released on 1988 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gene Transfer and Expression in Mammalian Cells

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Author :
Publisher : Newnes
ISBN 13 : 0080930352
Total Pages : 776 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Gene Transfer and Expression in Mammalian Cells by : S.C. Makrides

Download or read book Gene Transfer and Expression in Mammalian Cells written by S.C. Makrides and published by Newnes. This book was released on 2003-10-24 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: The production of proteins in mammalian cells is an important tool in numerous scientific and commercial areas. For example, proteins for human therapy, vaccination or diagnostic applications are typically produced in mammalian cells. Gene cloning, protein engineering, biochemical and biophysical characterization of proteins also require the use of gene expression in mammalian cells. Other applications in widespread use involve screening of libraries of chemical compounds in drug discovery, and the development of cell-based biosensors.This book presents a state-of-the-art comprehensive coverage of the technical aspects of gene expression in mammalian cells, written by experienced scientists working at the forefront of the field.

Gene Amplification

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Publisher :
ISBN 13 :
Total Pages : 370 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Gene Amplification by : Robert T. Schimke

Download or read book Gene Amplification written by Robert T. Schimke and published by . This book was released on 1982 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gene Transfer and Expression

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Publisher : Oxford University Press, USA
ISBN 13 : 9780716770046
Total Pages : 242 pages
Book Rating : 4.7/5 (7 download)

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Book Synopsis Gene Transfer and Expression by : Michael Kriegler

Download or read book Gene Transfer and Expression written by Michael Kriegler and published by Oxford University Press, USA. This book was released on 1990 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a descriptive, comprehensive catalogue of viral and cellular cis-acting elements and the latest expression vectors for obtaining optimum expression of foreign genes introduced into mammalian cells. Included is a selection of optimized, state-of-the-art protocols for transferring genes into mammalian cells and subsequently assaying for transfer and expression of the genes of interest. This unique volume describes in detail essential techniques for propagating cells and cell lines, DNA transfer techniques, drug selection and gene amplification techniques, expression cloning, subtractive hybridization and retrovirus-mediated gene transfer techniques. Also featured are highly sensitive assays for gene transfer and expression, including detection of DNA and RNA by both isotopic and non-isotopic detection methods as well as the most sensitive non-isotopic Western techniques for the detection of proteins.

The Mechanism of Gene Amplification in Mammalian Cell Lines Following Treatment with Hydroxyurea and Adriamycin

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (597 download)

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Book Synopsis The Mechanism of Gene Amplification in Mammalian Cell Lines Following Treatment with Hydroxyurea and Adriamycin by : Gillian Frances Atkinson

Download or read book The Mechanism of Gene Amplification in Mammalian Cell Lines Following Treatment with Hydroxyurea and Adriamycin written by Gillian Frances Atkinson and published by . This book was released on 1988 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gene Expression and Regulation in Mammalian Cells

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535138553
Total Pages : 336 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Gene Expression and Regulation in Mammalian Cells by : Fumiaki Uchiumi

Download or read book Gene Expression and Regulation in Mammalian Cells written by Fumiaki Uchiumi and published by BoD – Books on Demand. This book was released on 2018-02-21 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Central dogma" was presented by Dr. Francis Crick 60 years ago. The information of nucleotide sequences on DNAs is transcribed into RNAs by RNA polymerases. We learned the mechanisms of how transcription determines function of proteins and behaviour of cells and even how it brings appearances of organisms. This book is intended for scientists and medical researchers especially who are interested in the relationships between transcription and human diseases. This volume consists of an introductory chapter and 14 chapters, divided into 4 parts. Each chapter is written by experts in the basic scientific field. A collection of articles presented by active and laboratory-based investigators provides recent advances and progresses in the field of transcriptional regulation in mammalian cells.

The Mechanism of Gene Amplification in Mammalian Cell Lines Following Treatment with Hydroxyurea and Adriamycin

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (597 download)

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Book Synopsis The Mechanism of Gene Amplification in Mammalian Cell Lines Following Treatment with Hydroxyurea and Adriamycin by : G. F. Atkinson

Download or read book The Mechanism of Gene Amplification in Mammalian Cell Lines Following Treatment with Hydroxyurea and Adriamycin written by G. F. Atkinson and published by . This book was released on 1988 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gene Amplification in Mammalian Cells

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Author :
Publisher : CRC Press
ISBN 13 : 1000148092
Total Pages : 584 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Gene Amplification in Mammalian Cells by : Rodney E. Kellems

Download or read book Gene Amplification in Mammalian Cells written by Rodney E. Kellems and published by CRC Press. This book was released on 2020-08-26 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serves as a comprehensive review to the substantial impact of gene amplification in molecular biology, genetic engineering and medical science. The book covers the mechanism of gene amplification, organization and structure of amplified genes.

Gene Amplification and the Development of Drug Resistance

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Publisher :
ISBN 13 :
Total Pages : 170 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Gene Amplification and the Development of Drug Resistance by : Yvonne Wettergren

Download or read book Gene Amplification and the Development of Drug Resistance written by Yvonne Wettergren and published by . This book was released on 1994 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cell Line Development

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Publisher : Springer Science & Business Media
ISBN 13 : 9048122457
Total Pages : 259 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Cell Line Development by : Mohamed Al-Rubeai

Download or read book Cell Line Development written by Mohamed Al-Rubeai and published by Springer Science & Business Media. This book was released on 2009-08-11 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mammalian cell lines command an effective monopoly for the production of therapeutic proteins that require post-translational modifications. This unique advantage outweighs the costs associated with mammalian cell culture, which are far grater in terms of development time and manufacturing when compared to microbial culture. The development of cell lines has undergone several advances over the years, essentially to meet the requirement to cut the time and costs associated with using such a complex hosts as production platforms. This book provides a comprehensive guide to the methodology involved in the development of cell lines and the cell engineering approach that can be employed to enhance productivity, improve cell function, glycosylation and secretion and control apoptosis. It presents an overall picture of the current topics central to expression engineering including such topics as epigenetics and the use of technologies to overcome positional dependent inactivation, the use of promoter and enhancer sequences for expression of various transgenes, site directed engineering of defined chromosomal sites, and examination of the role of eukaryotic nucleus as the controller of expression of genes that are introduced for production of a desired product. It includes a review of selection methods for high producers and an application developed by a major biopharmaceutical industry to expedite the cell line development process. The potential of cell engineering approch to enhance cell lines through the manipulation of single genes that play important roles in key metabolic and regulatory pathways is also explored throughout.

Gene Delivery to Mammalian Cells

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Publisher : Springer Science & Business Media
ISBN 13 : 1592596495
Total Pages : 303 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Gene Delivery to Mammalian Cells by : William C. Heiser

Download or read book Gene Delivery to Mammalian Cells written by William C. Heiser and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experienced researchers describe in step-by-step detail methods that have proven most useful in delivering genes to mammalian cells. Volume 1 focuses on gene delivery by a variety of chemical and physical methods, including ultrasound, biolistics, peptides, PNA clamps, liposomes, microinjection, electroporation, particle bombardment, dendrimers, and hydrodynamics. Volume 2 details procedures for delivering genes to cells in vitro and in vivo, including the use of lentiviral vectors.