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Functional And Genetic Characterisation Of Major Effect Milk Composition Variants In Dairy Cattle
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Book Synopsis Functional and Genetic Characterisation of Major Effect Milk Composition Variants in Dairy Cattle by : Tania Alice Fink
Download or read book Functional and Genetic Characterisation of Major Effect Milk Composition Variants in Dairy Cattle written by Tania Alice Fink and published by . This book was released on 2017 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bovine milk production and composition traits are complex quantitative phenotypes, reflecting the interplay of many environmental and genetic factors influencing mammary and lactation biology. Despite a largely quantitative architecture, genetic mapping studies have identified a handful of major effect loci in dairy cattle, each containing a large number of trait-associated sequence variants. Identifying the specific variant causally responsible at these genetic signals requires extensive experimental follow-up, where many of the genomic regions implicate present no obvious candidate mutations. The association signal is instead represented by many non-coding variants that are difficult to functionally prioritise. The aim of the research described in this thesis was to investigate four such loci segregating in NZ dairy cattle, aiming to mechanistically link causative genes and variants to the milk production and composition effects. The results of this thesis describe the identification of expression quantitative trait loci at each of the four major associated regions, providing evidence that the variants responsible exert their phenotypic influence through the modulation of mammary gene expression. Further genetic and functional experiments were conducted to elucidate the mechanism by which the implicated variants impact gene expression. Highlights of this work include the demonstration of a new mechanism of effect for the largest and most highly cited causal mutation in the bovine literature. This work also reports the discovery of major milk production effects for a mutation previously only implicated in bovine growth and stature. This thesis also reports the development and optimisation of CRISPR-Cas9 mediated genome editing as a method for testing the function of regulatory variants directly. By presenting an efficient in vitro engineering approach in mammary cells, the work creates a framework to genetically isolate candidate variants, creating opportunities to study the major effect variants reported in this thesis, and investigate other as yet undefined milk composition loci. Taken together, the work presented in this thesis provides enhanced understanding of the mechanisms linking major effect genetic variants to bovine milk production and composition, and raises the profile of these and other variants as markers to incorporate in animal selection and breeding strategies.
Book Synopsis Designing Foods by : National Research Council
Download or read book Designing Foods written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This lively book examines recent trends in animal product consumption and diet; reviews industry efforts, policies, and programs aimed at improving the nutritional attributes of animal products; and offers suggestions for further research. In addition, the volume reviews dietary and health recommendations from major health organizations and notes specific target levels for nutrients.
Book Synopsis Recent Advances in Animal Nutrition by : W. Haresign
Download or read book Recent Advances in Animal Nutrition written by W. Haresign and published by Elsevier. This book was released on 2013-10-22 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Advances in Animal Nutrition-1981 is a collection of papers that discusses the effects of dietary fat on milk composition, relating it to the biochemistry of fat synthesis in the mammary gland. The influence of concentrates on milk composition as well as the pattern and level of concentrate feeding on milk output are also covered. The book describes the need for better utilization of grass and grass products in dairy production, the mineral and trace element requirements of pigs; the importance of anion-cation balance in poultry diets and its effects on performance levels; and the selenium and cobalt requirements of ruminants. The problems of medicinal residues in animal products and the toxicological effects of aflatoxin residues in animal products are also considered. People involved in agriculture, dairy production and animal nutrition will find the book useful.
Book Synopsis Safety of Genetically Engineered Foods by : National Research Council
Download or read book Safety of Genetically Engineered Foods written by National Research Council and published by National Academies Press. This book was released on 2004-07-08 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.
Download or read book Cattle Breeds written by Marleen Felius and published by . This book was released on 2007-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 1,000 cattle breeds from around the globe are cataloged in this monumental bovine reference. Each breed, including species found only in prehistory, is provided with a detailed physical description and a watercolor drawn to scale. Cattle are also classified into groups and subgroups according to geographical distribution, historical background, and physical features. Charts indicating breed lineage and records of crossbreeding, maps clearly depicting the location and distribution of authentic and derived breeds, and additional color photographs all round out this unprecedented resource.
Download or read book Milk from Grass written by C. Thomas and published by . This book was released on 1991 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genes written by Jonathan Slack and published by Oxford University Press, USA. This book was released on 2014 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores the discovery, nature, and role of genes in evolution and development.
Download or read book Milk Proteins written by C.A. Barth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the state of knowledge and progress of research on food proteins, and in particular, milk proteins. Its basis is the Symposium on Milk Proteins that was held at the Federal Dairy Research Centre in Kiel, FRG, in June, 1988. Scien tists from around the world attended and addressed pure, as well as applied fields of protein research and technology. This book is divided into five sections, each adapted from the symposium's invited lectures, short communications, and poster presentations. New criteria for the "bio logical value" of dietary proteins and their relationships are considered according to: - Milk Proteins and Nitrogen Equilibrium - Milk Proteins and Ligands - Milk Proteins: Structural and Genetic Aspects - Milk Proteins: Technological and Functional Aspects - Milk Proteins and Clinical Nutrition Generally, different dietary proteins are classified according to their "biological value," i.e., their capacity to cause different retention of nitrogen in the body. But we think there are other intriguing leads worth studying that may help to identify which dietary proteins are best recommended for specific dietary situations or clini cal conditions. In addition, we have taken into consideration new fields such as attempts to determine the three-dimensional structure of proteins using two-dimensional NMR spectroscopy, and the application of genetic engineering to the lactating cell. In other words, we are on the way to the transgenic cow with customized milk constituents and composition.
Book Synopsis The Genetics of Cattle, 2nd Edition by : Dorian Garrick
Download or read book The Genetics of Cattle, 2nd Edition written by Dorian Garrick and published by CABI. This book was released on 2014-11-28 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the time of domestication more than 10,000 years ago, cattle have played an increasingly crucial role in the development of human civilizations. Progress has been quite remarkable since the turn of the century; the sequencing of the bovine genome in 2009 launched new avenues for furthering our understanding of theoretical and practical aspects of cattle genetics. Covering a vast array of questions, this book reviews major topics from molecular and developmental genetics, disease resistance and immunogenetics to genetic improvement of dairy and beef breeds, addressing all current problems in the field. This second edition includes a new team of authors and completely new chapters on the genetics of fat production, nutrition, feed intake and efficiency, growth and body composition. Fully updated throughout, it provides a valuable resource on cattle genetics for researchers, breeders, veterinarians and postgraduate students.
Book Synopsis Advanced Dairy Chemistry by : Paul L. H. McSweeney
Download or read book Advanced Dairy Chemistry written by Paul L. H. McSweeney and published by Springer Science & Business Media. This book was released on 2009-04-20 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Advanced Dairy Chemistry series was first published in four volumes in the 1980s (under the title Developments in Dairy Chemistry) and revised in three volumes in the 1990s. The series is the leading reference source on dairy chemistry, providing in-depth coverage of milk proteins, lipids, lactose, water and minor constituents. Advanced Dairy Chemistry Volume 3: Lactose, Water, Salts, and Minor Constituents, Third Edition, reviews the extensive literature on lactose and its significance in milk products. This volume also reviews the literature on milk salts, vitamins, milk flavors and off-flavors and the behaviour of water in dairy products. Most topics covered in the second edition are retained in the current edition, which has been updated and expanded considerably. New chapters cover chemically and enzymatically prepared derivatives of lactose and oligosaccharides indigenous to milk. P.L.H. McSweeney Ph.D. is Associate Professor of Food Chemistry and P.F. Fox Ph.D., D.Sc. is Professor Emeritus of Food Chemistry at University College, Cork, Ireland.
Book Synopsis Animal Genomics by : Bhanu P. Chowdhary
Download or read book Animal Genomics written by Bhanu P. Chowdhary and published by S. Karger AG (Switzerland). This book was released on 2003 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication provides an update on the current status of gene maps in different livestock and pet/companion animal species. The findings summarized in species specific commentaries and original articles testify the rapid advances made in the field of animal genomics. Of significant interest is the fact that current investigations are providing headways for two important and exciting research fronts: targeted high-resolution mapping leading to the application of genomic information in addressing questions of economic and biological significance in animals, and the initiation of whole genome sequencing projects for some of the animal species. Like in humans and mice, this will set the stage for a new level of research and real time complex analysis of the genomes of these species. Animal Genomics signifies the beginning of a new era in this field and celebrates the achievements of the past 20 years of genomics research. It will be of special interest to researchers involved in genome analysis - both gross chromosomal as well as molecular - in various animal species, and to comparative and evolutionary geneticists.
Book Synopsis Proteomics in Domestic Animals: from Farm to Systems Biology by : Andre Martinho de Almeida
Download or read book Proteomics in Domestic Animals: from Farm to Systems Biology written by Andre Martinho de Almeida and published by Springer. This book was released on 2018-02-09 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteomics, like other post-genomics tools, has been growing at a rapid pace and has important applications in numerous fields of science. While its use in animal and veterinary sciences is still limited, there have been considerable advances in this field in recent years, in areas as diverse as physiology, nutrition and food of animal origin processing. This is mainly as a consequence of a wider availability and better understanding of proteomics methodologies by animal and veterinary researchers. This book provides a comprehensive, state-of-the-art account of the status of farm-animal proteomics research, focusing on the principles behind proteomics methodologies and its specific applications and offering clear example.
Book Synopsis Sustainable Food Production by : Paul Christou
Download or read book Sustainable Food Production written by Paul Christou and published by Springer. This book was released on 2012-12-05 with total page 1869 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gathering some 90 entries from the Encyclopedia of Sustainability Science and Technology, this book covers animal breeding and genetics for food, crop science and technology, ocean farming and sustainable aquaculture, transgenic livestock for food and more.
Book Synopsis The Sustainability of Agro-Food and Natural Resource Systems in the Mediterranean Basin by : Antonella Vastola
Download or read book The Sustainability of Agro-Food and Natural Resource Systems in the Mediterranean Basin written by Antonella Vastola and published by Springer. This book was released on 2015-04-24 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is focused on the challenges to implement sustainability in diverse contexts such as agribusiness, natural resource systems and new technologies. The experiences made by the researchers of the School of Agricultural, Forestry, Food and Environmental Science (SAFE) of the University of Basilicata offer a wide and multidisciplinary approach to the identification and testing of different solutions tailored to the economic, social and environmental characteristics of the region and the surrounding areas. Basilicata’s productive system is mainly based on activities related to the agricultural sector and exploitation of natural resources but it has seen, in recent years, an industrial development driven by the discovery of oil fields. SAFE research took up the challenge posed by market competition to create value through the sustainable use of renewable and non-renewable resources of the territory. Moreover, due to its unique geographical position in the middle of the Mediterranean basin, Basilicata is an excellent “open sky” laboratory for testing sustainable solutions adaptable to other Mediterranean areas. This collection of multidisciplinary case studies and research experiences from SAFE researchers and their scientific partners is a stimulating contribution to the debate on the development of sustainable techniques, methods and applications for the Mediterranean regions.
Book Synopsis Novel Proteins for Food, Pharmaceuticals, and Agriculture by : Maria Hayes
Download or read book Novel Proteins for Food, Pharmaceuticals, and Agriculture written by Maria Hayes and published by John Wiley & Sons. This book was released on 2018-11-28 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: A groundbreaking text that highlights the various sources, applications and advancements concerning proteins from novel and traditional sources Novel Proteins for Food, Pharmaceuticals and Agriculture offers a guide to the various sources, applications, and advancements that exist and are currently being researched concerning proteins from novel and traditional sources. The contributors—noted experts in the field—discuss sustainable protein resources and include illustrative examples of bioactive compounds isolated from several resources that have or could obtain high market value in specific markets. The text also explores a wide range of topics such as functional food formulations and pharmaceutical applications, and how they alter biological activity to provide therapeutic benefits, nutritional values and health protection. The authors also examine the techno-functional applications of proteins and looks at the screening process for identification of bioactive molecules derived from protein sources. In addition, the text provides insight into the market opportunities that exist for novel proteins such as insect, by-product derived, macroalgal and others. The authors also discuss the identification and commercialization of new proteins for various markets. This vital text: Puts the focus on the various sources, applications and advancements concerning proteins from novel and traditional sources Contains a discussion on how processing technologies currently applied to dairy could be applied to novel protein sources such as insect and macroalgal Reviews the sustainability of protein sources and restrictions that exist concerning development Offers ideas for creating an innovative and enterprising economy that is built on recent developments Details the potential to exploit key market opportunities in sports, infant and elderly nutrition and techno-functional protein applications Written for industrial researchers as well as PhD and Post-doctoral researchers, and undergraduate students studying biochemistry, food engineering and biological sciences and those interested in market developments, Novel Proteins for Food, Pharmaceuticals and Agriculture offers an essential guide to the sources, applications and most recent developments of the proteins from both innovative and traditional sources.
Book Synopsis Mason's World Encyclopedia of Livestock Breeds and Breeding, 2 Volume Pack by : Valerie Porter
Download or read book Mason's World Encyclopedia of Livestock Breeds and Breeding, 2 Volume Pack written by Valerie Porter and published by CABI. This book was released on 2016-03-09 with total page 1109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mason's World Encyclopedia of Livestock Breeds and Breeding describes breeds of livestock worldwide as well as a range of breed-related subjects such as husbandry, health and behaviour. This definitive and prestigious reference work presents easily accessible information on domestication (including wild ancestors and related species), genetics and breeding, livestock produce and markets, as well as breed conservation and the cultural and social aspects of livestock farming. Written by renowned livestock authorities, these volumes draw on the authors' lifelong interest and involvement in livestock breeds of the world, presenting a unique, comprehensive and fully cross-referenced guide to cattle, buffalo, horses, pigs, sheep, asses, goats, camelids, yak and other domesticants.
Book Synopsis Linear Models for the Prediction of Animal Breeding Values by : R. A. Mrode
Download or read book Linear Models for the Prediction of Animal Breeding Values written by R. A. Mrode and published by Cab International. This book was released on 2014 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prediction of producing desirable traits in offspring such as increased growth rate or superior meat, milk and wool production is a vital economic tool to the animal scientist. Summarizing the latest developments in genomics relating to animal breeding values and design of breeding programs, this new edition includes models of survival analysis, social interaction and sire and dam models, as well as advancements in the use of SNPs in the computation of genomic breeding values.
