Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Download Frontiers In Hemoglobinopathies New Insights And Methods full books in PDF, epub, and Kindle. Read online Frontiers In Hemoglobinopathies New Insights And Methods ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author : Roberta Risoluti
Publisher : Frontiers Media SA
ISBN 13 : 2889667626
Total Pages : 106 pages
Book Rating : 4.8/5 (896 download)
Download or read book Frontiers in Hemoglobinopathies: New Insights and Methods written by Roberta Risoluti and published by Frontiers Media SA. This book was released on 2021-05-12 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Zarina Abdul Latiff
Publisher : Frontiers Media SA
ISBN 13 : 283254486X
Total Pages : 90 pages
Book Rating : 4.8/5 (325 download)
Download or read book Insights in Thalassemia: From Genomics to Clinical Practice written by Zarina Abdul Latiff and published by Frontiers Media SA. This book was released on 2024-02-23 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: IN LOVING MEMORY of Dr. Zarina Abdul Latiff. Thalassemia is a genetically heterogenous group of hemoglobinopathy disorders, characterised by imbalanced production of the α-globin or β-globin subunits of hemoglobin. Although the causative genotype is a key determinant of disease severity, the clinical spectrum and phenotype are affected by secondary and tertiary genetic modifiers. The public health and clinical burden of the disease is apparent with 1.5% of the global population being carriers and an estimated 400,000 affected births annually, with the majority in lower-middle-income countries. Although diagnostics and clinical management have evolved over the last decade, there is still much to be addressed in terms prevention, utility of molecular diagnostics, treatment outcome and quality of life.
Author : Sanjeev Kumar Sharma
Publisher : Springer Nature
ISBN 13 : 9811958025
Total Pages : 962 pages
Book Rating : 4.8/5 (119 download)
Download or read book Basics of Hematopoietic Stem Cell Transplant written by Sanjeev Kumar Sharma and published by Springer Nature. This book was released on 2023-07-24 with total page 962 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is quick guide on the hematopoietic stem cell transplant (SCT), also called bone marrow transplant (BMT) - an evolving field of hematology and hemato-oncology. This book covers the various types of stem cell transplants like autologous and allogeneic stem cell transplants, indications, ways of doing a transplant, and stem cell transplants basic principles. Written in a question-answer format, readers will find it more interesting as one question sequentially leads to another. This book explains the complications of SCT in individual chapters along with the biology of T cells which are the most important cells involved in the success of SCT This book is beneficial to the budding hematologists, oncologists, and postgraduates interested in SCT and helps students in their exams. The book would be helpful for readers globally as SCT is a procedure done worldwide and is an ever-increasing field for treating various benign and malignant hematological diseases.
Author : Richard Van Wijk
Publisher : Frontiers Media SA
ISBN 13 : 2889662705
Total Pages : 141 pages
Book Rating : 4.8/5 (896 download)
Download or read book Pathophysiology of Rare Hemolytic Anemias written by Richard Van Wijk and published by Frontiers Media SA. This book was released on 2020-12-23 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author : Osaro Erhabor
Publisher : BoD – Books on Demand
ISBN 13 : 1838803130
Total Pages : 236 pages
Book Rating : 4.8/5 (388 download)
Download or read book Human Blood Group Systems and Haemoglobinopathies written by Osaro Erhabor and published by BoD – Books on Demand. This book was released on 2021-02-17 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has seen remarkable improvements and advances in the fields of blood transfusion and hematology, particularly with regards to advances in science, technology, method development, quality, standardization, and governance. This book provides more evidenced-based insight into the field of blood transfusion and the management of hemoglobinopathies.
Author : Christine A. Gleason
Publisher : Elsevier Health Sciences
ISBN 13 : 1455727148
Total Pages : 1536 pages
Book Rating : 4.4/5 (557 download)
Download or read book Avery's Diseases of the Newborn E-Book written by Christine A. Gleason and published by Elsevier Health Sciences. This book was released on 2011-08-12 with total page 1536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Avery’s Diseases of the Newborn, edited by Christine A. Gleason and Sherin U. Devaskar, is a practical, clinical reference for diagnosing and managing of all the important diseases affecting newborns. Thoroughly revised by a team of new editors, this edition provides new perspectives and updated coverage of genetics, nutrition, respiratory conditions, MRSA, neonatal pain, cardiovascular fetal interventions, care of the late preterm infant, and more. This authoritative reference is ideal as a clinical resource or subspecialty review tool. Treat newborns effectively with focused coverage of diagnosis and management, including pertinent developmental physiology and the pathogenesis of neonatal problems. Meet every challenge you face in neonatology with Avery’s authoritative, comprehensive clinical resource and subspecialty review tool. Navigate quickly and easily with extensive cross-referencing throughout the organ-related sections. Stay current with coverage of hot topics including MRSA, neonatal pain, cardiovascular fetal interventions, care of the late preterm infant, and the developing intestinal microbiome. Tap into the fresh perspectives of new editors who provide extensive updates throughout, particularly on genetic and respiratory disorders. Apply the latest nutritional findings with thorough discussions of this valuable information in the more comprehensive nutrition section. Master the fundamentals of neonatology through the greater emphasis on developmental biology and pathobiology.
Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher :
ISBN 13 :
Total Pages : 1520 pages
Book Rating : 4.3/5 (91 download)
Download or read book Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1991 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies and published by . This book was released on 1990 with total page 1520 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Christine A Gleason, MD
Publisher : Elsevier Health Sciences
ISBN 13 : 8131254720
Total Pages : 1973 pages
Book Rating : 4.1/5 (312 download)
Download or read book Avery's Diseases of the Newborn: First South Asia Edition-E-Book written by Christine A Gleason, MD and published by Elsevier Health Sciences. This book was released on 2018-05-23 with total page 1973 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the evaluation and management of every key disease and condition affecting newborns, Avery's Diseases of the Newborn, by Drs. Christine A. Gleason and Sandra E. Juul, remains your #1 source for practical, clinically relevant information in this fast-changing field. You'll find the specific strategies you need to confidently diagnose and treat this unique patient population, easy-to-use single volume that focuses on key areas of practice. Now in a thoroughly revised first South Asia Edition, this highly respected reference is an authoritative clinical resource for neonatal practitioners. Provides up-to-date information on every aspect of newborn evaluation and management in a new, visually improved format featuring more than 500 all-new illustrations integrated within each chapter. Includes greatly expanded Neurology and Hematology sections that highlight the knowledge and expertise of new co-editor, Dr. Sandra E. Juul. Features all-new chapters on Palliative Care, Gastroesophageal Reflux, Platelet Disorders, Transfusion Therapy, Hypertension, and The Ear and Hearing Disorders, as well as expanded coverage of brain injury and neuroprotective strategies in the preterm and term infant. Contains new Key Points boxes at the beginning of every chapter. Brings you up to date on current topics such as the evolving epidemic of neonatal abstinence syndrome and the new clinical uses of ultrasound
Author : Carsten Werner Lederer
Publisher : Frontiers Media SA
ISBN 13 : 2889716880
Total Pages : 218 pages
Book Rating : 4.8/5 (897 download)
Download or read book Mutation-Specific Gene Editing for Blood Disorders written by Carsten Werner Lederer and published by Frontiers Media SA. This book was released on 2021-11-25 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Miccio holds patents related to viral gene delivery vectors. The Topic Editors acknowledge the use of image material from kindpng.com and from Crystal and Annie Spratt on unsplash.com.
Author : Isam Jaber Al-Zwaini
Publisher : BoD – Books on Demand
ISBN 13 : 1789233666
Total Pages : 140 pages
Book Rating : 4.7/5 (892 download)
Download or read book Thalassemia and Other Hemolytic Anemias written by Isam Jaber Al-Zwaini and published by BoD – Books on Demand. This book was released on 2018-07-11 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thalassemia is a very common disease first described by pediatrician Thomas Benton Cooley in 1925 who described it in a patient of Italian origin. At that time, it was designated as Cooley's anemia. George Hoyt Whipple, a Nobel prize winner, and W. L. Bradford, a professor of pediatrics at the University of Rochester, coined the term thalassemia in 1936, which in Greek means anemia of the sea (Thalassa means "sea", and emia means "blood"), due to the fact that it is very common in the area of the Mediterranean Sea. This name is actually misleading because it can occur everywhere in the world. Thalassemia is not a single disease; it is rather a group of hereditary disorders of the production of globulin chain of the hemoglobin. Throughout the world, thalassemia affects approximately 4.4 of every 10,000 live births. It represents a major social and emotional impact on the patient and his family and a major burden on health services where the prevalence is high.
Author : Richard Van Wijk
Publisher : Frontiers Media SA
ISBN 13 : 2889716996
Total Pages : 167 pages
Book Rating : 4.8/5 (897 download)
Download or read book New Methods for Red Blood Cell Research and Diagnosis written by Richard Van Wijk and published by Frontiers Media SA. This book was released on 2021-11-26 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topic Editors Dr. Paola Bianchi and Dr. Richard Van Wijk provide consultancy to Agios Pharmaceuticals. Dr. Richard Van Wijk has research support from RR Mechatronics and Agios Pharmaceuticals.
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309047986
Total Pages : 353 pages
Book Rating : 4.3/5 (9 download)
Download or read book Assessing Genetic Risks written by Institute of Medicine and published by National Academies Press. This book was released on 1994-01-01 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.
Author : Punam Malik
Publisher : Springer
ISBN 13 : 1493972995
Total Pages : 254 pages
Book Rating : 4.4/5 (939 download)
Download or read book Gene and Cell Therapies for Beta-Globinopathies written by Punam Malik and published by Springer. This book was released on 2017-11-09 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemoglobin defects, specifically sickle cell disease & thalassemia, combined, constitute the most common monogenic disorders in the world. In fact, nearly 2% of the world’s population carries a globin gene mutation. The transfer of the corrective globin gene through the HSC compartment by allogeneic HSC transplantation (HSCT) has already proven curative in both SCD and thalassemia patients, and provides the proof of concept that genetic manipulation of the defective organ might be equally therapeutic. However, procedural toxicities and the requirement of an HLA-matched sibling donor limit this approach to a fraction of affected individuals. The editors review the progress & the state of the field in HSCT for hemoglobinopathies & shed light on the major changes expected in the next decade. Although allogeneic HSCT is a curative option, it is limited by the availability of matched donors, which are often available only to 15-20% of patients. An alternative to allogeneic HS CT is genetic correction of autologous HSCs, to overcome donor availability & immune side effects. This Book reviews the progress made on additive gene therapy approaches & the current state of the field. Finally, targeted genetic correction is emerging as a novel therapeutic strategy in the hemoglobinopathies. Although ideal, the inefficiency of targeted correction was rate limiting for translation of this technology to the clinic. With advancements in zinc finger nucleases and TALE endonuclease mediated targeted correction, correction frequencies in hematopoietic stem cells is now reaching levels that may become clinically relevant. Furthermore, the ability to generate autologous embryonic stem cell like cells from primary somatic cells (skin fibroblasts or hematopoietic cells) of the affected individual has allowed for the potential application of genetic correction strategies.This Book reviews upcoming genetic strategies to reactivate fetal hemoglobin production and research advances.
Author : Martin H. Steinberg
Publisher : Cambridge University Press
ISBN 13 : 0521875196
Total Pages : 883 pages
Book Rating : 4.5/5 (218 download)
Download or read book Disorders of Hemoglobin written by Martin H. Steinberg and published by Cambridge University Press. This book was released on 2009-08-17 with total page 883 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised new edition of the definitive reference on disorders of hemoglobin.
Author : Jeffrey Laurence
Publisher : Academic Press
ISBN 13 : 0128005645
Total Pages : 347 pages
Book Rating : 4.1/5 (28 download)
Download or read book Translating Gene Therapy to the Clinic written by Jeffrey Laurence and published by Academic Press. This book was released on 2014-11-14 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translating Gene Therapy to the Clinic, edited by Dr. Jeffrey Laurence and Michael Franklin, follows the recent, much-lauded special issue of Translational Research in emphasizing clinical milestones and critical barriers to further progress in the clinic. This comprehensive text provides a background for understanding the techniques involved in human gene therapy trials, and expands upon the disease-specific situations in which these new approaches currently have the greatest therapeutic application or potential, and those areas most in need of future research. It emphasizes methods, tools, and experimental approaches used by leaders in the field of translational gene therapy. The book promotes cross-disciplinary communication between the sub-specialties of medicine, and remains unified in theme. - Presents impactful and widely supported research across the spectrum of science, method, implementation and clinical application - Offers disease-based coverage from expert clinician-scientists, covering everything from arthritis to congestive heart failure, as it details specific progress and barriers for current translational use - Provides key background information from immune response through genome engineering and gene transfer, relevant information for practicing clinicians contemplating enrolling patients in gene therapy trials
Author : Simon Charles Heath
Publisher : Frontiers Media SA
ISBN 13 : 283253645X
Total Pages : 172 pages
Book Rating : 4.8/5 (325 download)
Download or read book Insights in Statistical Genetics and Methodology: 2022 written by Simon Charles Heath and published by Frontiers Media SA. This book was released on 2023-10-24 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is part of the Insights in Frontiers in Genetics series.
Author : Sara Ricardo
Publisher : Frontiers Media SA
ISBN 13 : 2832529208
Total Pages : 123 pages
Book Rating : 4.8/5 (325 download)
Download or read book New molecular approaches to improve gynecological cancer management written by Sara Ricardo and published by Frontiers Media SA. This book was released on 2023-07-06 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt:
