From Breakthrough To Blockbuster

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From Breakthrough to Blockbuster

Author : Donald L. Drakeman
Publisher : Oxford University Press
ISBN 13 : 0195084004
Total Pages : 241 pages
Book Rating : 4.1/5 (95 download)

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Book Synopsis From Breakthrough to Blockbuster by : Donald L. Drakeman

Download or read book From Breakthrough to Blockbuster written by Donald L. Drakeman and published by Oxford University Press. This book was released on 2022 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. How could a large collection of small companies, most with fewer than 50 employees, compete in one of the world's most breathtakingly expensive and highly regulated industries? This book shows how biotech companies have met the challenge by creating nearly 40% more of the most important treatments for unmet medical needs. Moreover, they have done so with much lower overall costs. The book focuses on both the companies themselves and the broader biotech ecosystem that supports them. Its portrait of the crucial roles played by academic research, venture capital, contract research organizations, the capital markets, and pharmaceutical companies shows how a supportive environment enabled the entrepreneurial biotech industry to create novel medicines with unprecedented efficiency. In doing so, it also offers insights for any industry seeking to innovate in uncertain and ambiguous conditions. Looking to the future, it concludes that biomedical research will continue to be most effective in the hands of a large group of small companies as long as national healthcare policies allow the rest of the ecosystem to continue to thrive"--

From Breakthrough to Blockbuster

Author : Donald L. Drakeman
Publisher : Oxford University Press
ISBN 13 : 0197626300
Total Pages : 241 pages
Book Rating : 4.1/5 (976 download)

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Book Synopsis From Breakthrough to Blockbuster by : Donald L. Drakeman

Download or read book From Breakthrough to Blockbuster written by Donald L. Drakeman and published by Oxford University Press. This book was released on 2022-02-14 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Financial Times Business Top Title March 2022 How could a large collection of small companies, most with fewer than 50 employees, rise to compete with Big Pharma, one of the world's most breathtakingly expensive and highly regulated industries? Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. Biotech companies have met the challenge by creating nearly 40% more of the most important treatments for previously unmet medical needs. Moreover, they have done so with much lower overall costs. From Breakthrough to Blockbuster: The Business of Biotechnology focuses on both the companies themselves and the broader biotech ecosystem that supports them. It paints a portrait of the crucial roles played by academic research, venture capital, contract research organizations, the capital markets, and pharmaceutical companies, demonstrating how a supportive environment enabled the entrepreneurial biotech industry to create novel medicines with unprecedented efficiency. In doing so, it also offers insights for any industry seeking to innovate in uncertain and ambiguous conditions.

Biotechnology Entrepreneurship

Author : Craig Shimasaki
Publisher : Academic Press
ISBN 13 : 0124047475
Total Pages : 488 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Biotechnology Entrepreneurship by : Craig Shimasaki

Download or read book Biotechnology Entrepreneurship written by Craig Shimasaki and published by Academic Press. This book was released on 2014-04-08 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: As an authoritative guide to biotechnology enterprise and entrepreneurship, Biotechnology Entrepreneurship and Management supports the international community in training the biotechnology leaders of tomorrow. Outlining fundamental concepts vital to graduate students and practitioners entering the biotech industry in management or in any entrepreneurial capacity, Biotechnology Entrepreneurship and Management provides tested strategies and hard-won lessons from a leading board of educators and practitioners. It provides a ‘how-to’ for individuals training at any level for the biotech industry, from macro to micro. Coverage ranges from the initial challenge of translating a technology idea into a working business case, through securing angel investment, and in managing all aspects of the result: business valuation, business development, partnering, biological manufacturing, FDA approvals and regulatory requirements. An engaging and user-friendly style is complemented by diverse diagrams, graphics and business flow charts with decision trees to support effective management and decision making. Provides tested strategies and lessons in an engaging and user-friendly style supplemented by tailored pedagogy, training tips and overview sidebars Case studies are interspersed throughout each chapter to support key concepts and best practices. Enhanced by use of numerous detailed graphics, tables and flow charts

Instant Appeal

Author : Vicki KUNKEL
Publisher : Amacom Books
ISBN 13 : 0814410219
Total Pages : 306 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Instant Appeal by : Vicki KUNKEL

Download or read book Instant Appeal written by Vicki KUNKEL and published by Amacom Books. This book was released on 2008-11-26 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover the hidden secrets of mass appeal...and use them to create unbreakable allegiance for products, people, and ideas!

Blockbuster Drugs

Author : Jie Jack Li
Publisher : Oxford University Press
ISBN 13 : 0199737681
Total Pages : 238 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Blockbuster Drugs by : Jie Jack Li

Download or read book Blockbuster Drugs written by Jie Jack Li and published by Oxford University Press. This book was released on 2014 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book uses the cases of several landmark drugs to discuss the history of the pharmaceutical industry, and discusses what could be next"--Provided by publisher.

Science Lessons

Author : Gordon M. Binder
Publisher : Harvard Business Review Press
ISBN 13 :
Total Pages : 326 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Science Lessons by : Gordon M. Binder

Download or read book Science Lessons written by Gordon M. Binder and published by Harvard Business Review Press. This book was released on 2008 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Under Gordon Binder's leadership, Amgen became the world's largest and most successful biotech company in the world. This text describes what it really takes to manage risk, financing, creative employees, and intellectual property on the international stage.

The Breakthrough

Author : Charles Graeber
Publisher : Twelve
ISBN 13 : 145556849X
Total Pages : 298 pages
Book Rating : 4.4/5 (555 download)

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Book Synopsis The Breakthrough by : Charles Graeber

Download or read book The Breakthrough written by Charles Graeber and published by Twelve. This book was released on 2018-11-13 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Follow along as this New York Times bestselling author details the astonishing scientific discovery of the code to unleashing the human immune system to fight in this "captivating and heartbreaking" book (The Wall Street Journal). For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold? As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses -- tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it. In The Breakthrough, New York Times bestselling author of The Good Nurse Charles Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step -- harnessing the wealth of new information to create modern and more effective patient therapies -- is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease. Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history.

Hedy's Folly

Author : Richard Rhodes
Publisher : Vintage
ISBN 13 : 0307742954
Total Pages : 298 pages
Book Rating : 4.3/5 (77 download)

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Book Synopsis Hedy's Folly by : Richard Rhodes

Download or read book Hedy's Folly written by Richard Rhodes and published by Vintage. This book was released on 2012-08-07 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pulitzer Prize-winning author Richard Rhodes delivers a remarkable story of science history: how a ravishing film star and an avant-garde composer invented spread-spectrum radio, the technology that made wireless phones, GPS systems, and many other devices possible. Beginning at a Hollywood dinner table, Hedy's Folly tells a wild story of innovation that culminates in U.S. patent number 2,292,387 for a "secret communication system." Along the way Rhodes weaves together Hollywood’s golden era, the history of Vienna, 1920s Paris, weapons design, music, a tutorial on patent law and a brief treatise on transmission technology. Narrated with the rigor and charisma we've come to expect of Rhodes, it is a remarkable narrative adventure about spread-spectrum radio's genesis and unlikely amateur inventors collaborating to change the world.

From Alchemy To Ipo

Author : Cynthia Robbins-roth
Publisher : Perseus Books
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis From Alchemy To Ipo by : Cynthia Robbins-roth

Download or read book From Alchemy To Ipo written by Cynthia Robbins-roth and published by Perseus Books. This book was released on 2000-05-18 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fascinating glimpse inside the life-and-death business of biotechnology.

Can't Slow Down

Author : Michaelangelo Matos
Publisher : Hachette Books
ISBN 13 : 0306903350
Total Pages : 480 pages
Book Rating : 4.3/5 (69 download)

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Book Synopsis Can't Slow Down by : Michaelangelo Matos

Download or read book Can't Slow Down written by Michaelangelo Matos and published by Hachette Books. This book was released on 2020-12-08 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Rolling Stone-Kirkus Best Music Book of 2020 The definitive account of pop music in the mid-eighties, from Prince and Madonna to the underground hip-hop, indie rock, and club scenes Everybody knows the hits of 1984 - pop music's greatest year. From "Thriller" to "Purple Rain," "Hello" to "Against All Odds," "What's Love Got to Do with It" to "Wake Me Up Before You Go-Go," these iconic songs continue to dominate advertising, karaoke nights, and the soundtracks for film classics (Boogie Nights) and TV hits (Stranger Things). But the story of that thrilling, turbulent time, an era when Top 40 radio was both the leading edge of popular culture and a moral battleground, has never been told with the full detail it deserves - until now. Can't Slow Down is the definitive portrait of the exploding world of mid-eighties pop and the time it defined, from Cold War anxiety to the home-computer revolution. Big acts like Michael Jackson (Thriller), Prince (Purple Rain), Madonna (Like a Virgin), Bruce Springsteen (Born in the U.S.A.), and George Michael (Wham!'s Make It Big) rubbed shoulders with the stars of the fermenting scenes of hip-hop, indie rock, and club music. Rigorously researched, mapping the entire terrain of American pop, with crucial side trips to the UK and Jamaica, from the biz to the stars to the upstarts and beyond, Can't Slow Down is a vivid journey to the very moment when pop was remaking itself, and the culture at large - one hit at a time.

Breakthrough

Author : James O'Keefe
Publisher : Simon and Schuster
ISBN 13 : 1476706174
Total Pages : 352 pages
Book Rating : 4.4/5 (767 download)

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Book Synopsis Breakthrough by : James O'Keefe

Download or read book Breakthrough written by James O'Keefe and published by Simon and Schuster. This book was released on 2013-06-18 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this hard-hitting look at the way media and government conspire to protect the status quo, a controversial ambush journalist shows readers what happens when a young citizen journalist challenges some of America's most powerful and protected organizations.

Nano

Author : John Robert Marlow
Publisher : Macmillan
ISBN 13 : 0765301296
Total Pages : 385 pages
Book Rating : 4.7/5 (653 download)

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Book Synopsis Nano by : John Robert Marlow

Download or read book Nano written by John Robert Marlow and published by Macmillan. This book was released on 2004-02 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: "As this fast-paced nanothriller unfolds, readers are taken on a tour de force of nanotechnology's promises and perils - until the fate of the earth itself hangs in the balance."--BOOK JACKET.

Hit Makers

Author : Derek Thompson
Publisher : Penguin
ISBN 13 : 1101980346
Total Pages : 368 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Hit Makers by : Derek Thompson

Download or read book Hit Makers written by Derek Thompson and published by Penguin. This book was released on 2017-02-07 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: NATIONAL BESTSELLER A Book of the Year Selection for Inc. and Library Journal “This book picks up where The Tipping Point left off." -- Adam Grant, Wharton professor and New York Times bestselling author of ORIGINALS and GIVE AND TAKE Nothing “goes viral.” If you think a popular movie, song, or app came out of nowhere to become a word-of-mouth success in today’s crowded media environment, you’re missing the real story. Each blockbuster has a secret history—of power, influence, dark broadcasters, and passionate cults that turn some new products into cultural phenomena. Even the most brilliant ideas wither in obscurity if they fail to connect with the right network, and the consumers that matter most aren't the early adopters, but rather their friends, followers, and imitators -- the audience of your audience. In his groundbreaking investigation, Atlantic senior editor Derek Thompson uncovers the hidden psychology of why we like what we like and reveals the economics of cultural markets that invisibly shape our lives. Shattering the sentimental myths of hit-making that dominate pop culture and business, Thompson shows quality is insufficient for success, nobody has "good taste," and some of the most popular products in history were one bad break away from utter failure. It may be a new world, but there are some enduring truths to what audiences and consumers want. People love a familiar surprise: a product that is bold, yet sneakily recognizable. Every business, every artist, every person looking to promote themselves and their work wants to know what makes some works so successful while others disappear. Hit Makers is a magical mystery tour through the last century of pop culture blockbusters and the most valuable currency of the twenty-first century—people’s attention. From the dawn of impressionist art to the future of Facebook, from small Etsy designers to the origin of Star Wars, Derek Thompson leaves no pet rock unturned to tell the fascinating story of how culture happens and why things become popular. In Hit Makers, Derek Thompson investigates: · The secret link between ESPN's sticky programming and the The Weeknd's catchy choruses · Why Facebook is today’s most important newspaper · How advertising critics predicted Donald Trump · The 5th grader who accidentally launched "Rock Around the Clock," the biggest hit in rock and roll history · How Barack Obama and his speechwriters think of themselves as songwriters · How Disney conquered the world—but the future of hits belongs to savvy amateurs and individuals · The French collector who accidentally created the Impressionist canon · Quantitative evidence that the biggest music hits aren’t always the best · Why almost all Hollywood blockbusters are sequels, reboots, and adaptations · Why one year--1991--is responsible for the way pop music sounds today · Why another year --1932--created the business model of film · How data scientists proved that “going viral” is a myth · How 19th century immigration patterns explain the most heard song in the Western Hemisphere

The Billion-Dollar Molecule

Author : Barry Werth
Publisher : Simon and Schuster
ISBN 13 : 143912681X
Total Pages : 480 pages
Book Rating : 4.4/5 (391 download)

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Book Synopsis The Billion-Dollar Molecule by : Barry Werth

Download or read book The Billion-Dollar Molecule written by Barry Werth and published by Simon and Schuster. This book was released on 2013-08-20 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing—atom by atom—both a new life-saving immunosuppressant drug, and a drug to combat the virus that causes AIDS. You will be hooked from start to finish, as you go from the labs, where obsessive, fiercely competitive scientists struggle for a breakthrough, to Wall Street, where the wheeling and dealing takes on a life of its own, as Boger courts investors and finally decides to take Vertex public. Here is a fascinating no-holds-barred account of the business of science, which includes an updated epilogue about the most recent developments in the quest for a drug to cure AIDS.

Liberal Education and Citizenship in a Free Society

Author : Justin Buckley Dyer
Publisher : University of Missouri Press
ISBN 13 : 0826274889
Total Pages : 462 pages
Book Rating : 4.8/5 (262 download)

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Book Synopsis Liberal Education and Citizenship in a Free Society by : Justin Buckley Dyer

Download or read book Liberal Education and Citizenship in a Free Society written by Justin Buckley Dyer and published by University of Missouri Press. This book was released on 2023-07-24 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: The liberal arts university has been in decline since well before the virtualization of campus life, increasingly inviting public skepticism about its viability as an institution of personal, civic, and professional growth. New technologies that might have brought people together have instead frustrated the university’s capacity to foster thoughtful citizenship among tomorrow’s leaders and exacerbated socioeconomic inequalities that are poisoning America’s civic culture. With Liberal Education and Citizenship in a Free Society, a collection of 19 original essays, editors Justin Dyer and Constantine Vassiliou present the work of a diverse group of scholars to assess the value of a liberal arts education in the face of market, technological, cultural, and political forces shaping higher learning today.

The Pathway to Operational Excellence in the Pharmaceutical Industry

Author : Thomas Friedli
Publisher :
ISBN 13 : 9783871934001
Total Pages : 365 pages
Book Rating : 4.9/5 (34 download)

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Book Synopsis The Pathway to Operational Excellence in the Pharmaceutical Industry by : Thomas Friedli

Download or read book The Pathway to Operational Excellence in the Pharmaceutical Industry written by Thomas Friedli and published by . This book was released on 2010 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neue Technologien, sich wandelnde Geschäftsstrategien, Kostendruck auf Hersteller und Zulieferer, migrierende globale Wertschöpfungsketten sowie neue regulatorische Anforderungen sind die Herausforderungen der Pharmaindustrie. Um in allen Bereichen Exzellenz zu erreichen gilt es, den Fokus auf die Menschen zu richten. Sie planen, bewirken, verbessern und erfinden neue Strategien, erfahren, Systeme und Strukturen. Die Fähigkeit zur Überwindung der inneren Trägheit eines Unternehmens macht den Unterschied. Die höchsten FundE-Ausgaben verzeichneten die Unternehmen, die sich nicht weiter mit einem eingeführten und evaluierten Verfahren beschäftigten. Das beeinträchtigte Innovationen im Produkt- und Substanzbereich. Veränderungen werden an Geschwindigkeit und Umfang zunehmen. Hier setzt die Operational Excellence ein. Dies impliziert, das Herstellungspotenzial zu entwickeln, als Grundlage einzigartiger Geschäftsstrategien. Dazu erforderlich sind Exzellenz in Führung und Management, Methoden und Tools sowie Technologie und Innovation. Zielgruppen:- Pharmazeutische Industrie- Zulieferindustrie- Fachhochschulen / Universitäten- Beratungsunternehmen- Behörden.

Genentech

Author : Sally Smith Hughes
Publisher : University of Chicago Press
ISBN 13 : 0226359204
Total Pages : 232 pages
Book Rating : 4.2/5 (263 download)

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Book Synopsis Genentech by : Sally Smith Hughes

Download or read book Genentech written by Sally Smith Hughes and published by University of Chicago Press. This book was released on 2011-09-21 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading, at that point the largest gain in stock market history. Coming at a time of economic recession and declining technological competitiveness in the United States, the event provoked banner headlines and ignited a period of speculative frenzy over biotechnology as a revolutionary means for creating new and better kinds of pharmaceuticals, untold profit, and a possible solution to national economic malaise. Drawing from an unparalleled collection of interviews with early biotech players, Sally Smith Hughes offers the first book-length history of this pioneering company, depicting Genentech’s improbable creation, precarious youth, and ascent to immense prosperity. Hughes provides intimate portraits of the people significant to Genentech’s science and business, including cofounders Herbert Boyer and Robert Swanson, and in doing so sheds new light on how personality affects the growth of science. By placing Genentech’s founders, followers, opponents, victims, and beneficiaries in context, Hughes also demonstrates how science interacts with commercial and legal interests and university research, and with government regulation, venture capital, and commercial profits. Integrating the scientific, the corporate, the contextual, and the personal, Genentech tells the story of biotechnology as it is not often told, as a risky and improbable entrepreneurial venture that had to overcome a number of powerful forces working against it.