Fundamentals and Applications of Fourier Transform Mass Spectrometry

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Publisher : Elsevier
ISBN 13 : 0128140143
Total Pages : 778 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Fundamentals and Applications of Fourier Transform Mass Spectrometry by : Philippe Schmitt-Kopplin

Download or read book Fundamentals and Applications of Fourier Transform Mass Spectrometry written by Philippe Schmitt-Kopplin and published by Elsevier. This book was released on 2019-08-11 with total page 778 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data. Covers FT-ICR-MS and Orbitrap’s fundamentals, enhancing researcher knowledge Includes details on ion sources, data processing, chemical analysis and imaging Provides examples across the wide spectrum of applications, including omics, environmental, chemical, pharmaceutical and food analysis

Asphaltenes, Heavy Oils, and Petroleomics

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Publisher : Springer Science & Business Media
ISBN 13 : 0387689036
Total Pages : 677 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis Asphaltenes, Heavy Oils, and Petroleomics by : Oliver C. Mullins

Download or read book Asphaltenes, Heavy Oils, and Petroleomics written by Oliver C. Mullins and published by Springer Science & Business Media. This book was released on 2007-11-08 with total page 677 pages. Available in PDF, EPUB and Kindle. Book excerpt: With substantial contributions from experienced industrial scientists and engineers, this work will have real application towards improving process efficiency and improvement in the trillion-dollar global petroleum industry. It presents an overview of the emerging field of petroleomics, which endeavors to understand the fundamental components of crude oil. Petroleomics promises to revolutionize petroleum science in much the same way that genomics transformed the study of medicine not long ago. Asphaltenes are a particular focus, with many chapters devoted to the analysis of their structure and properties.

Proteomic Profiling and Analytical Chemistry

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Publisher : Elsevier
ISBN 13 : 0444636900
Total Pages : 300 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Proteomic Profiling and Analytical Chemistry by : Pawel Ciborowski

Download or read book Proteomic Profiling and Analytical Chemistry written by Pawel Ciborowski and published by Elsevier. This book was released on 2016-03-02 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteomic Profiling and Analytical Chemistry: The Crossroads, Second Edition helps scientists without a strong background in analytical chemistry to understand principles of the multistep proteomic experiment necessary for its successful completion. It also helps researchers who do have an analytical chemistry background to break into the proteomics field. Highlighting points of junction between proteomics and analytical chemistry, this resource links experimental design with analytical measurements, data analysis, and quality control. This targeted point of view will help both biologists and chemists to better understand all components of a complex proteomic study. The book provides detailed coverage of experimental aspects such as sample preparation, protein extraction and precipitation, gel electrophoresis, microarrays, dynamics of fluorescent dyes, and more. The key feature of this book is a direct link between multistep proteomic strategy and quality control routinely applied in analytical chemistry. This second edition features a new chapter on SWATH-MS, substantial updates to all chapters, including proteomic database search and analytical quantification, expanded discussion of post-hoc statistical tests, and additional content on validation in proteomics. Covers the analytical consequences of protein and peptide modifications that may have a profound effect on how and what researchers actually measure Includes practical examples illustrating the importance of problems in quantitation and validation of biomarkers Helps in designing and executing proteomic experiments with sound analytics

FT-ICR/MS

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Author :
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 326 pages
Book Rating : 4.:/5 (51 download)

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Book Synopsis FT-ICR/MS by : Bruce Asamoto

Download or read book FT-ICR/MS written by Bruce Asamoto and published by Wiley-VCH. This book was released on 1991 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Medical Applications of Mass Spectrometry

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Publisher : Elsevier
ISBN 13 : 0080554652
Total Pages : 607 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Medical Applications of Mass Spectrometry by : Karoly Vekey

Download or read book Medical Applications of Mass Spectrometry written by Karoly Vekey and published by Elsevier. This book was released on 2011-08-11 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine.The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging. * Provides a broad look at how the medical field is benefiting from advances in mass spectrometry.* Guides the reader from basic principles and methods to cutting edge applications.* There is NO comparable book on the market to fill this fast growing field.

Fourier Transforms in Spectroscopy

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Publisher : John Wiley & Sons
ISBN 13 : 3527635017
Total Pages : 271 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Fourier Transforms in Spectroscopy by : Jyrki Kauppinen

Download or read book Fourier Transforms in Spectroscopy written by Jyrki Kauppinen and published by John Wiley & Sons. This book was released on 2011-02-10 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: This modern approach to the subject is clearly and logically structured, and gives readers an understanding of the essence of Fourier transforms and their applications. All important aspects are included with respect to their use with optical spectroscopic data. Based on popular lectures, the authors provide the mathematical fundamentals and numerical applications which are essential in practical use. The main part of the book is dedicated to applications of FT in signal processing and spectroscopy, with IR and NIR, NMR and mass spectrometry dealt with both from a theoretical and practical point of view. Some aspects, linear prediction for example, are explained here thoroughly for the first time.

Chemical Imaging Analysis

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Publisher : Elsevier
ISBN 13 : 0444634509
Total Pages : 493 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Chemical Imaging Analysis by : Freddy Adams

Download or read book Chemical Imaging Analysis written by Freddy Adams and published by Elsevier. This book was released on 2015-06-06 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Imaging Analysis covers the advancements made over the last 50 years in chemical imaging analysis, including different analytical techniques and the ways they were developed and refined to link the composition and structure of manmade and natural materials at the nano/micro scale to the functional behavior at the macroscopic scale. In a development process that started in the early 1960s, a variety of specialized analytical techniques was developed – or adapted from existing techniques – and these techniques have matured into versatile and powerful tools for visualizing structural and compositional heterogeneity. This text explores that journey, providing a general overview of imaging techniques in diverse fields, including mass spectrometry, optical spectrometry including X-rays, electron microscopy, and beam techniques. Provides comprehensive coverage of analytical techniques used in chemical imaging analysis Explores a variety of specialized techniques Provides a general overview of imaging techniques in diverse fields

Fourier Transforms in NMR, Optical, and Mass Spectrometry

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Publisher : Elsevier
ISBN 13 : 148329384X
Total Pages : 470 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Fourier Transforms in NMR, Optical, and Mass Spectrometry by : A.G. Marshall

Download or read book Fourier Transforms in NMR, Optical, and Mass Spectrometry written by A.G. Marshall and published by Elsevier. This book was released on 2016-02-25 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by spectroscopists for spectroscopists, here is a book which is not only a valuable handbook and reference work, but also an ideal teaching text for Fourier transform methods as they are applied in spectroscopy. It offers the first unified treatment of the three most popular types of FT/spectroscopy, with uniform notation and complete indexing of specialized terms. All mathematics is self-contained, and requires only a knowledge of simple calculus. The main emphasis is on pictures and physical analogs rather than detailed algebra. Instructive problems, presented at the end of each chapter, offer extensions of the basic treatment. Solutions are given or outlined for all problems. The book offers a wealth of practical information to spectroscopists. Non-ideal effects are treated in detail: noise (source- and detector-limited); non-linear response; limits to spectrometer performance based on finite detection period, finite data size, mis-phasing, etc. Common puzzles and paradoxes are explained: e.g. use of mathematically complex variables to represent physically real quantities; interpretation of negative frequency signals; on-resonance vs. off-resonance response; interpolation (when it helps and when it doesn't); ultimate accuracy of the data; differences between linearly- and circularly-polarized radiation; multiplex advantage or disadvantage, etc. Chapter 1 introduces the fundamental line shapes encountered in spectroscopy, from a simple classical mass-on-a-spring model. The Fourier transform relationship between the time-domain response to a sudden impulse and the steady-state frequency-domain response (absorption and dispersion spectra) to a continuous oscillation is established and illustrated. Chapters 2 and 3 summarize the basic mathematics (definitions, formulas, theorems, and examples) for continuous (analog) and discrete (digital) Fourier transforms, and their practical implications. Experimental aspects which are common to the signal (Chapter 4) and noise (Chapter 5) in all forms of Fourier transform spectrometry are followed by separate chapters for treatment of those features which are unique to FT/MS, FT/optical, FT/NMR, and other types of FT/spectroscopy. The list of references includes both historical and comprehensive reviews and monographs, along with articles describing several key developments. The appendices provide instant access to FT integrals and fast algorithms as well as a pictorial library of common Fourier transform function pairs. The comprehensive index is designed to enable the reader to locate particular key words, including those with more than one name.

Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

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Publisher :
ISBN 13 :
Total Pages : 222 pages
Book Rating : 4.:/5 (256 download)

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Book Synopsis Fourier Transform Ion Cyclotron Resonance Mass Spectrometry by : M. B. Comisarow

Download or read book Fourier Transform Ion Cyclotron Resonance Mass Spectrometry written by M. B. Comisarow and published by . This book was released on 1986 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry

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Publisher : Elsevier
ISBN 13 : 0128189991
Total Pages : 272 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry by : Bindesh Shrestha

Download or read book Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry written by Bindesh Shrestha and published by Elsevier. This book was released on 2021-04-23 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging mass spectrometry (MS) techniques are often utilized without an understanding of their underlying principles, making it difficult for scientists to determine when and how they can exploit MS to visualize their biomolecules of interest. Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry is an essential reference to help scientists determine the status and strategies of biomolecule analysis, describing its many applications for diverse classes of biomolecules. The book builds a foundation of imaging MS knowledge by introducing ionization sources, sample preparation, visualization guidelines, molecule identification, quantification, data analysis, etc. The second section contains chapters focused on case studies on analyzing a biomolecule class of molecules. Case studies include an introduction/background, and a summary of successful imaging MS studies with illustrative figures and future directions. Provides the introductory foundations of imaging mass spectrometry for those new to the technique Organized by topic to facilitate a quick deep dive, allowing researchers to immediately apply the imaging MS techniques to their work Includes case studies summarizing the imaging MS techniques developed for the class of molecules

Fourier, Hadamard, and Hilbert Transforms in Chemistry

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Publisher : Springer Science & Business Media
ISBN 13 : 1489903364
Total Pages : 564 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Fourier, Hadamard, and Hilbert Transforms in Chemistry by : Alan Marshall

Download or read book Fourier, Hadamard, and Hilbert Transforms in Chemistry written by Alan Marshall and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: In virtually all types of experiments in which a response is analyzed as a function of frequency (e. g. , a spectrum), transform techniques can significantly improve data acquisition and/or data reduct ion. Research-level nuclear magnet ic resonance and infra-red spectra are already obtained almost exclusively by Fourier transform methods, because Fourier transform NMR and IR spectrometers have been commercially available since the late 1960·s. Similar transform techniques are equally valuable (but less well-known) for a wide range of other chemical applications for which commercial instruments are only now becoming available: for example, the first corrmercial Fourier transform mass spectrometer was introduced this year (1981) by Nicolet Instrument Corporation. The purpose of this volume is to acquaint practicing chemists with the basis, advantages, and applica of Fourier, Hadamard, and Hilbert transforms in chemistry. For tions almost all chapters, the author is the investigator who was the first to apply such methods in that field. The basis and advantages of transform techniques are described in Chapter 1. Many of these aspects were understood and first applied by infrared astronomers in the 1950·s, in order to improve the otherwise unacceptably poor signal-to-noise ratio of their spec tra. However, the computations required to reduce the data were painfully slow, and required a 1 arge computer.

Improvements in Our Basic Understanding of Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

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Publisher :
ISBN 13 :
Total Pages : 416 pages
Book Rating : 4.:/5 (241 download)

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Book Synopsis Improvements in Our Basic Understanding of Fourier Transform Ion Cyclotron Resonance Mass Spectrometry by : Peter Byron Grosshans

Download or read book Improvements in Our Basic Understanding of Fourier Transform Ion Cyclotron Resonance Mass Spectrometry written by Peter Byron Grosshans and published by . This book was released on 1990 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Spectroscopy and Modeling of Biomolecular Building Blocks

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Publisher : Elsevier
ISBN 13 : 0080558224
Total Pages : 499 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Spectroscopy and Modeling of Biomolecular Building Blocks by : Jean-Pierre Schermann

Download or read book Spectroscopy and Modeling of Biomolecular Building Blocks written by Jean-Pierre Schermann and published by Elsevier. This book was released on 2007-10-16 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spectroscopy and Modeling of Biomolecular Building Blocks presents an overview of recent advances in the intertwining of the following research fields: photon and electron spectroscopy, quantum chemistry, modelling and mass-spectrometry. The coupling of these disciplines offers a new point of view to the understanding of isolated elementary building blocks of biomolecules and their assemblies. It allows the unambiguous separation between intrinsic properties of biomolecular systems and those induced by the presence of their environment. The first chapters provide background in modelling (I), frequency-resolved spectroscopy using microwave, infrared and UV photons, time-resolved spectroscopy in the femtosecond domain and energy-resolved electron spectroscopy (II) and production of gas-phase neutral and ionic biomolecular species, mass-spectrometry, ion mobility and BIRD techniques (III). Chapter IV is devoted to case studies of gas-phase experimental investigations coupled to quantum or classical calculations. The topics are structural studies of nucleobases and oligonucleotides, peptides and proteins, sugars; neuromolecules; non-covalent complexes; chiral systems, interactions of low-energy electrons with biomolecules in the radiation chemistry context and very large gas-phase biomolecular systems. The fifth chapter concerns the link between gas-phase and liquid-phase. Different treatments of solvation are illustrated through examples pointing out the influence of progressive addition of water molecules upon properties of nucleobases, peptides, sugars and neuromolecules. Offer a new perspective to the understanding of isolated elementary building blocks of bio molecules Includes case studies of experimental investigations coupled to quantum or classical calculations

FT-ICR/MS

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Publisher : Wiley
ISBN 13 : 9780471187349
Total Pages : 306 pages
Book Rating : 4.1/5 (873 download)

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Book Synopsis FT-ICR/MS by : B. Asamoto

Download or read book FT-ICR/MS written by B. Asamoto and published by Wiley. This book was released on 1991-11-11 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: An in-depth look at many of the applications where FT-ICR mass spectrometry is implemented. Contributing authors emphasize ways in which FT-ICR provides superior information to that of other types of mass spectrometers as well as where it may be less informative than other mass spectrometers. With the information provided, analytical chemists will be capable of assessing the usefulness of FT-ICR versus other mass spectrometric methods for their particular needs. Comprehensive chapters cover the history of ICR and other techniques based on the cyclotron principles of mass analysis and offer a descriptive explanation of the theory involved in fourier transform detection and analysis. Chapters also detail features and areas of active research in instrumentation and some specifications on commercial instruments as well as the home-built American Cyanamid instrument. Application chapters cover one technique in detail and illustrate its particular area of analysis.

Practical Aspects of Trapped Ion Mass Spectrometry, Volume IV

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Publisher : CRC Press
ISBN 13 : 1420083724
Total Pages : 952 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Practical Aspects of Trapped Ion Mass Spectrometry, Volume IV by : Raymond E. March

Download or read book Practical Aspects of Trapped Ion Mass Spectrometry, Volume IV written by Raymond E. March and published by CRC Press. This book was released on 2010-05-25 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting the substantial increase in popularity of quadrupole ion traps and Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometers, Practical Aspects of Trapped Ion Mass Spectrometry, Volume IV: Theory and Instrumentation explores the historical origins of the latest advances in this expanding field. It covers new methods for trapp

Chemical Analysis of Non-antimicrobial Veterinary Drug Residues in Food

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Publisher : John Wiley & Sons
ISBN 13 : 1118695070
Total Pages : 641 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Chemical Analysis of Non-antimicrobial Veterinary Drug Residues in Food by : Jack F. Kay

Download or read book Chemical Analysis of Non-antimicrobial Veterinary Drug Residues in Food written by Jack F. Kay and published by John Wiley & Sons. This book was released on 2016-11-14 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a single-source reference for readers interested in the development of analytical methods for analyzing non-antimicrobial veterinary drug residues in food Provides a comprehensive set of information in the area of consumer food safety and international trade Covers general issues related to analytical quality control and quality assurance, measurement uncertainty, screening and confirmatory methods Details many techniques including nanotechnology and aptamer based assays covering current and potential applications for non-antimicrobial veterinary drugs Provides guidance for analysis of banned drugs including natural and synthetic steroids, Resorcylic acid lactones, and Beta-agonists

Analyzing Biomolecular Interactions by Mass Spectrometry

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Publisher : John Wiley & Sons
ISBN 13 : 3527334645
Total Pages : 402 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Analyzing Biomolecular Interactions by Mass Spectrometry by : Jeroen Kool

Download or read book Analyzing Biomolecular Interactions by Mass Spectrometry written by Jeroen Kool and published by John Wiley & Sons. This book was released on 2015-05-04 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section also emphasizes the use of ion mobility MS, capture-compound approaches, chemical proteomics and interactomics. The third and final part discusses other important technologies frequently employed in interaction studies, such as biosensors and microarrays. For pharmaceutical, analytical, protein, environmental and biochemists, as well as those working in pharmaceutical and analytical laboratories.