Final Report Of The National Academies Human Embryonic Stem Cell Research Advisory Committee And 2010 Amendments To The National Academies Guidelines For Human Embryonic Stem Cell Research

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Final Report of the National Academies' Human Embryonic Stem Cell Research Advisory Committee and 2010 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309156009
Total Pages : 58 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Final Report of the National Academies' Human Embryonic Stem Cell Research Advisory Committee and 2010 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research by : National Research Council

Download or read book Final Report of the National Academies' Human Embryonic Stem Cell Research Advisory Committee and 2010 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research written by National Research Council and published by National Academies Press. This book was released on 2010-08-13 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2005, the National Academies released the book, Guidelines for Human Embryonic Stem Cell Research, which offered a common set of ethical standards for a field that, due to the absence of comprehensive federal funding, was lacking national standards for research. In order to keep the Guidelines up to date, given the rapid pace of scientific and policy developments in the field of stem cell research, the Human Embryonic Stem Cell Research Advisory Committee was established in 2006 with support from The Ellison Medical Foundation, The Greenwall Foundation, and the Howard Hughes Medical Institute. As it did in 2007 and 2008, the Committee identified issues that warranted revision, and this book addresses those issues in a third and final set of amendments. Specifically, this book sets out an updated version of the National Academies' Guidelines, one that takes into account the new, expanded role of the NIH in overseeing hES cell research. It also identifies those avenues of continuing National Academies' involvement deemed most valuable by the research community and other significant stakeholders.

Guidelines for Human Embryonic Stem Cell Research

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309096537
Total Pages : 224 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Guidelines for Human Embryonic Stem Cell Research by : National Research Council

Download or read book Guidelines for Human Embryonic Stem Cell Research written by National Research Council and published by National Academies Press. This book was released on 2005-09-15 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1998, the volume of research being conducted using human embryonic stem (hES) cells has expanded primarily using private funds because of restrictions on the use of federal funds for such research. Given limited federal involvement, privately funded hES cell research has thus far been carried out under a patchwork of existing regulations, many of which were not designed with this research specifically in mind. In addition, hES cell research touches on many ethical, legal, scientific, and policy issues that are of concern to the public. This report provides guidelines for the conduct of hES cell research to address both ethical and scientific concerns. The guidelines are intended to enhance the integrity of privately funded hES cell research by encouraging responsible practices in the conduct of that research.

Human Genome Editing

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309452880
Total Pages : 329 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Human Genome Editing by : National Academies of Sciences, Engineering, and Medicine

Download or read book Human Genome Editing written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-08-13 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.

Juridification in Bioethics

Author : Calvin Wai-Loon Ho
Publisher : World Scientific
ISBN 13 : 1911299646
Total Pages : 504 pages
Book Rating : 4.9/5 (112 download)

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Book Synopsis Juridification in Bioethics by : Calvin Wai-Loon Ho

Download or read book Juridification in Bioethics written by Calvin Wai-Loon Ho and published by World Scientific. This book was released on 2016-07-28 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is 'legal' about bioethics? What are the ideas and artefacts that bioethics encompasses, and how are they related to law? What is the role of law in bioethics? In this work, Calvin Ho attempts to address these questions in the context of the governance of human pluripotent stem cell research. In essence, he argues that the hybridization of law, through processes, devices and techniques of juridification, has helped to constitute bioethics as a public sphere and an emergent civic epistemology. Drawing on his multi-sited ethnographic fieldwork and on Actor-Network-Theory, Ho explains how the law has, through bioethics, contributed to the scientific and public understanding of human pluripotent stem cell research and its artefacts, particularly the embryo and human-animal combinations. Although the focus of his work is on bioethical developments in Singapore over a period of more than 15 years, parallel developments in key jurisdictions (especially the United States of America and the United Kingdom) and in international science policy are also evaluated. It is through appreciating how it has progressed that bioethics will be better able to engage with future challenges presented by advances in human embryo research and gene editing techniques, among others.

Embryonic Stem Cells and the Law

Author : Joshua Weiser
Publisher : Springer Nature
ISBN 13 : 3031597508
Total Pages : 286 pages
Book Rating : 4.0/5 (315 download)

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Book Synopsis Embryonic Stem Cells and the Law by : Joshua Weiser

Download or read book Embryonic Stem Cells and the Law written by Joshua Weiser and published by Springer Nature. This book was released on with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Regenerative Medicine and Stem Cell Biology

Author : Nagwa El-Badri
Publisher : Springer Nature
ISBN 13 : 3030553590
Total Pages : 374 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Regenerative Medicine and Stem Cell Biology by : Nagwa El-Badri

Download or read book Regenerative Medicine and Stem Cell Biology written by Nagwa El-Badri and published by Springer Nature. This book was released on 2020-11-27 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers the basic aspects of stem cell research and applications in regenerative medicine. Each chapter includes a didactic component and a practical section. The book offers readers insights into: How to identify the basic concepts of stem cell biology and the molecular regulation of pluripotency and stem cell development. How to produce induced pluripotent stem cells (iPSCs) and the basics of transfection. The biology of adult stem cells, with particular emphasis on mesenchymal stromal cells and hematopoietic stem cells, and the basic mechanisms that regulate them. How cancer stem cells arise and metastasize, and their properties. How to develop the skills needed to isolate, differentiate and characterize adult stem The clinical significance of stem cell research and the potential problems that need to be overcome. Evaluating the use of stem cells for tissue engineering and therapies (the amniotic membrane) The applications of bio-nanotechnology in stem cell research. How epigenetic mechanisms, including various DNA modifications and histone dynamics, are involved in regulating the potentiality and differentiation of stem cells. The scientific methods, ethical considerations and implications of stem cell research.

The International Law of Biotechnology

Author : Matthias Herdegen
Publisher : Edward Elgar Publishing
ISBN 13 : 1035302055
Total Pages : 219 pages
Book Rating : 4.0/5 (353 download)

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Book Synopsis The International Law of Biotechnology by : Matthias Herdegen

Download or read book The International Law of Biotechnology written by Matthias Herdegen and published by Edward Elgar Publishing. This book was released on 2023-01-20 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this thoroughly updated second edition, Matthias Herdegen provides a comprehensive and contemporary assessment of the regulation of biotechnology processes and products from an international and comparative perspective, complete with analysis of intricate legal and ethical debates.

Institutional Review Board: Management and Function

Author : Public Responsibility in Medicine & Research (PRIM&R),
Publisher : Jones & Bartlett Learning
ISBN 13 : 1284235521
Total Pages : 1113 pages
Book Rating : 4.2/5 (842 download)

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Book Synopsis Institutional Review Board: Management and Function by : Public Responsibility in Medicine & Research (PRIM&R),

Download or read book Institutional Review Board: Management and Function written by Public Responsibility in Medicine & Research (PRIM&R), and published by Jones & Bartlett Learning. This book was released on 2021-03-01 with total page 1113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Institutional Review Board (IRB) members and oversight personnel face challenges with research involving new technology, management of big data, globalization of research, and more complex federal regulations. Institutional Review Board: Management and Function, Third Edition provides everything IRBs and administrators need to know about efficiently managing and effectively operating a modern and compliant system of protecting human research subjects. This trusted reference manual has been extensively updated to reflect the 2018 revisions to the Federal Policy for the Protection of Human Subjects (Common Rule). An essential resource for both seasoned and novice IRB administrators and members, Institutional Review Board: Management and Function provides comprehensive and understandable interpretations of the regulations, clear descriptions of the ethical principles on which the regulations are based, and practical step-by-step guidance for effectively implementing regulatory oversight.

Chimera's Children

Author : David Albert Jones
Publisher : Bloomsbury Publishing
ISBN 13 : 1441125388
Total Pages : 208 pages
Book Rating : 4.4/5 (411 download)

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Book Synopsis Chimera's Children by : David Albert Jones

Download or read book Chimera's Children written by David Albert Jones and published by Bloomsbury Publishing. This book was released on 2012-11-02 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: The idea of human-nonhuman combinations has been a recurrent theme throughout the history of humanity. From the myths of the Minotaur and the centaurs in ancient Greece to the dogheads of the Middle Ages right through to the monsters of modern science fiction, these beings have always been a source of fascination. In recent years, however, biomedical advances have demonstrated the potential to make these entities a reality through the creation of inter-species combinations. As a result, pressing and perplexing ethical questions arise. Introducing the reader to the historical context of human-nonhuman experimentation and potential future developments, this volume offers clarification, analysis and a thorough overview of the ethical challenges relating to human-nonhuman chimeras, true hybrids, cybrids and other combinations. This book is the first accessible survey of the different ethical dilemmas facing contemporary society in the creation of human-nonhuman embryonic, foetal and postnatal entities. These include important cultural, legal, philosophical and religious perspectives. As such it will act as a springboard for future debate.

Human Cloning

Author : Kerry Lynn Macintosh
Publisher : Cambridge University Press
ISBN 13 : 1139852108
Total Pages : pages
Book Rating : 4.1/5 (398 download)

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Book Synopsis Human Cloning by : Kerry Lynn Macintosh

Download or read book Human Cloning written by Kerry Lynn Macintosh and published by Cambridge University Press. This book was released on 2012-10-29 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Since Dolly the sheep was born, controversy has swirled around the technology of cloning. We recoil at the prospect of human copies, manufactured men and women, nefarious impersonators and resurrections of the dead. Such reactions have serious legal consequences: lawmakers have banned stem cell research along with the cloning of babies. But what if our minds have been playing tricks on us? What if everything we thought we knew about human cloning is rooted in intuition rather than fact? Human Cloning: Four Fallacies and their Legal Consequences is a rollicking ride through science, psychology and the law. Drawing on sources ranging from science fiction films to the Congressional Record, this book unmasks the role that psychological essentialism has played in bringing about cloning bans. It explains how hidden intuitions have caused conservatives and liberals to act contrary to their own most cherished ideals and values.

Biotechnological Inventions and Patentability of Life

Author : Andrea Stazi
Publisher : Edward Elgar Publishing
ISBN 13 : 1784715905
Total Pages : 336 pages
Book Rating : 4.7/5 (847 download)

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Book Synopsis Biotechnological Inventions and Patentability of Life by : Andrea Stazi

Download or read book Biotechnological Inventions and Patentability of Life written by Andrea Stazi and published by Edward Elgar Publishing. This book was released on 2015-05-29 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: In todayês technological world, biotechnology is one of the most innovative and highly invested-in industries for research, in the field of science. This book analyses the forms and limitations of patent protection recognition for biotechnological inve

Third-Party Reproduction

Author : James M. Goldfarb
Publisher : Springer Science & Business Media
ISBN 13 : 1461471699
Total Pages : 232 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Third-Party Reproduction by : James M. Goldfarb

Download or read book Third-Party Reproduction written by James M. Goldfarb and published by Springer Science & Business Media. This book was released on 2013-10-07 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first IVF conceived birth in 1978 resulted in a significant growth of third party reproductive options which continue to raise ethical, legal, and psychological questions. Third party reproduction procedures can involve as many as five people: sperm donor, egg donor, gestational carrier, and intended parents. Third-Party Reproduction: A Comprehensive Guide utilizes experts in the field to address the medical, psychological, ethical and legal aspects of sperm donation, egg donation, embryo donation, and the use of gestational carriers. In addition, there are chapters on the medical and ethical aspects of posthumous reproduction, religious aspects of third party reproduction, and how to avoid pitfalls of third party reproduction. Aimed at physicians, trainees, psychologists, nurses, and social workers whose practices may include patients considering third party reproduction, the intent of this book is to provide a comprehensive and practical overview of the many aspects of third party reproduction to help all those involved to better understand them. Patients considering third party reproduction may also find value in this book.

Research Regulatory Compliance

Author : Mark A. Suckow
Publisher : Academic Press
ISBN 13 : 0124200656
Total Pages : 344 pages
Book Rating : 4.1/5 (242 download)

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Book Synopsis Research Regulatory Compliance by : Mark A. Suckow

Download or read book Research Regulatory Compliance written by Mark A. Suckow and published by Academic Press. This book was released on 2015-06-14 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research Regulatory Compliance offers the latest information on regulations and compliance in the laboratory. With the increasing complexity of regulations and need for institutional infrastructure to deal with compliance of animal use issues, as well as a requirement surrounding human subjects, this publication provides reputable guidance and information. The book is extremely helpful as a resource for researchers, administrators, and technicians in the laboratory, and is also a great asset for faculty or new researchers coming in to the laboratory environment. It will help prepare users for the deluge of regulatory and compliance issues they will face while conducting their scientific programs. The book is edited and authored by known leaders in the field of compliance and regulations, and contains extensive research on the topics. It represents the new standard for information in every laboratory. Provides a “one-stop" , go-to resource for the many regulatory and compliance issues that affect laboratory study and research models Extremely helpful as a resource for researchers, administrators, and technicians in the laboratory, and also a great asset for faculty or new researchers coming in to the laboratory environment Focuses on United States regulations, covering both animal models and human subjects Written and edited by known leaders in the field of regulatory compliance who bring many years of collective experience to the book

Life Before Birth

Author : Bonnie Steinbock
Publisher : Oxford University Press
ISBN 13 : 9780199712076
Total Pages : 328 pages
Book Rating : 4.7/5 (12 download)

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Book Synopsis Life Before Birth by : Bonnie Steinbock

Download or read book Life Before Birth written by Bonnie Steinbock and published by Oxford University Press. This book was released on 2011-07-11 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life Before Birth provides a coherent framework for addressing bioethical issues in which the moral status of embryos and fetuses is relevant. It is based on the "interest view" which ascribes moral standing to beings with interests, and connects the possession of interests with the capacity for conscious awareness or sentience. The theoretical framework is applied to ethical and legal topics, including abortion, prenatal torts, wrongful life, the crime of feticide, substance abuse by pregnant women, compulsory cesareans, assisted reproduction, and stem cell research. Along the way, difficult philosophical problems, such as identity and the non-identity problem are thoroughly explored. The book will be of interest not only to philosophers, but also physicians, lawyers, policy makers, and anyone perplexed by the many difficulties surrounding the unborn. "Bonnie Steinbock's excellent book is . . . consistent, thoroughgoing, and intelligible." --Nature "Steinbock's book is valuable for all interested in the ethical/legal issues surrounding abortion, prenatal injury and liability, maternal-fetal conflict, and fetal/embryo research. The author provides an excellent historical overview of these issues, but she also addresses the issues from the stance of a particular theory of moral status, namely, interest theory. This gives coherence to her discussion as well as allowing testing of the viability of interest theory." --Choice "A focused, lucid, analytically fine-grained discussion of a wide variety of problems. . . extremely useful as a survey of the current state of the debate." --Religious Studies Review "Merits serious consideration by physicians. Steinbock's interests-based approach treats all questions as open -- another and most welcome breath of fresh air." -New England Journal of Medicine "An extremely valuable contribution to the literature. The author carefully identifies the many bioethical issues to which the status of embryos and fetuses is relevant....She thoroughly reviews the extensive medical, bioethical, and legal literature on all of these issues, offering well-developed critiques of many standard positions. She articulates and thoughtfully defends interesting positions on all of theses topics. Anyone with an interest in these issues will learn a great deal from her knowledgeable and judicious treatment of them." -- The Journal of Clinical Ethics

Advanced Therapies in Regenerative Medicine

Author : Jan-Thorsten Schantz
Publisher : World Scientific Publishing Company
ISBN 13 : 9814630667
Total Pages : 300 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis Advanced Therapies in Regenerative Medicine by : Jan-Thorsten Schantz

Download or read book Advanced Therapies in Regenerative Medicine written by Jan-Thorsten Schantz and published by World Scientific Publishing Company. This book was released on 2015-03-30 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine is a fast developing field which has led to a paradigm shift in treatment of various diseases. Clinician-scientists worldwide constantly develop novel approaches in various medical specialties (surgery, internal medicine, oncology, neurology, gynecology, pediatrics, etc.) using gene therapy approaches, innovative biomaterials or stem cell based therapies. It is difficult even for experts to find out what has already reached a clinical stage. The aim of the second volume in this series is to provide the reader with a current update on the latest therapeutic developments. As such, both patients and doctors will find the information contained within this manual to be useful and relevant. The editors are both international leaders in the field of regenerative medicine, and both possess a broad spectrum of experience from basic research to clinical application and commercialization.

Mitochondrial Replacement Techniques

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309388708
Total Pages : 201 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Mitochondrial Replacement Techniques by : National Academies of Sciences, Engineering, and Medicine

Download or read book Mitochondrial Replacement Techniques written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-04-17 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondrial replacement techniques (MRTs) are designed to prevent the transmission of mitochondrial DNA (mtDNA) diseases from mother to child. While MRTs, if effective, could satisfy a desire of women seeking to have a genetically related child without the risk of passing on mtDNA disease, the technique raises significant ethical and social issues. It would create offspring who have genetic material from two women, something never sanctioned in humans, and would create mitochondrial changes that could be heritable (in female offspring), and therefore passed on in perpetuity. The manipulation would be performed on eggs or embryos, would affect every cell of the resulting individual, and once carried out this genetic manipulation is not reversible. Mitochondrial Replacement Techniques considers the implications of manipulating mitochondrial content both in children born to women as a result of participating in these studies and in descendants of any female offspring. This study examines the ethical and social issues related to MRTs, outlines principles that would provide a framework and foundation for oversight of MRTs, and develops recommendations to inform the Food and Drug Administration's consideration of investigational new drug applications.

Experiments in Democracy

Author : Benjamin J. Hurlbut
Publisher : Columbia University Press
ISBN 13 : 0231542917
Total Pages : 376 pages
Book Rating : 4.2/5 (315 download)

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Book Synopsis Experiments in Democracy by : Benjamin J. Hurlbut

Download or read book Experiments in Democracy written by Benjamin J. Hurlbut and published by Columbia University Press. This book was released on 2017-01-31 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human embryo research touches upon strongly felt moral convictions, and it raises such deep questions about the promise and perils of scientific progress that debate over its development has become a moral and political imperative. From in vitro fertilization to embryonic stem cell research, cloning, and gene editing, Americans have repeatedly struggled with how to define the moral status of the human embryo, whether to limit its experimental uses, and how to contend with sharply divided public moral perspectives on governing science. Experiments in Democracy presents a history of American debates over human embryo research from the late 1960s to the present, exploring their crucial role in shaping norms, practices, and institutions of deliberation governing the ethical challenges of modern bioscience. J. Benjamin Hurlbut details how scientists, bioethicists, policymakers, and other public figures have attempted to answer a question of great consequence: how should the public reason about aspects of science and technology that effect fundamental dimensions of human life? Through a study of one of the most significant science policy controversies in the history of the United States, Experiments in Democracy paints a portrait of the complex relationship between science and democracy, and of U.S. society's evolving approaches to evaluating and governing science's most challenging breakthroughs.