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Fast Facts Leukemia
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Book Synopsis Fast Facts: Leukemia by : Justin Loke
Download or read book Fast Facts: Leukemia written by Justin Loke and published by Karger Medical and Scientific Publishers. This book was released on 2022-02-22 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leukemia is a hematologic malignancy arising from hematopoietic stem cells (HSCs) in the bone marrow. Starting with a detailed description of hematopoiesis and what goes wrong in leukemia, this concise guide covers all aspects of the four most common subtypes of the disease. Although the incidence and prevalence of leukemia are rising worldwide, survival rates are also increasing. However, both the effects of the disease and the adverse effects of treatment remain complex challenges. Yet, as our understanding of the molecular landscape increases, therapeutic options are becoming more personalized. This revised and updated second edition of 'Fast Facts: Leukemia' addresses the causes and risk factors for each subtype of leukemia, the initial and confirmatory diagnostic tests, and the latest treatment options. Designed as a comprehensive primer for physician assistants, nurse practitioners, primary care providers, oncology nurses, hematology/ oncology trainees and pharmacists, this resource will help the non-specialist and those in training to identify leukemia early and provide a thorough understanding of the pathology and genetic basis of the disease, treatment options, and effective approaches to emergency and supportive care. Table of Contents: • Understanding blood and its components • What is leukemia? • Epidemiology, etiology and risk factors • Diagnosis • Staging and general management • Supportive care • Emergencies in leukemia
Book Synopsis Fast Facts for Patients: Chronic Lymphocytic Leukemia by : Kathryn Huntley
Download or read book Fast Facts for Patients: Chronic Lymphocytic Leukemia written by Kathryn Huntley and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic lymphocytic leukemia (CLL) is a slow-growing type of blood cancer and the most common form of leukemia in adults. CLL results in large numbers of abnormal B lymphocytes in the bone marrow and prevents the production of healthy blood cells. It is more commonly diagnosed in older people: almost 80% of cases are in people over 60 years old. Changes in chromosomes or genes in some patients affect how the disease develops and what treatment is prescribed. CLL cannot be completely cured but many people will have a normal lifespan and a good quality of life.
Book Synopsis Fast Facts: Acute Myeloid Leukemia by : William Blum
Download or read book Fast Facts: Acute Myeloid Leukemia written by William Blum and published by Karger Medical and Scientific Publishers. This book was released on 2018-05-14 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: This last year has seen the approval of the first targeted treatments for acute myeloid leukemia (AML) - following decades with no new developments and a poor prognosis for most patients with the disease. The new drugs reflect the remarkable progress that has been made in our understanding of the pathophysiology of AML and its underlying cytogenetic and molecular abnormalities - which differ not only between patients but also within a patient over time and with treatment. 'Fast Facts: Acute Myeloid Leukemia' provides a comprehensive yet concise foundation for understanding AML: from basic epidemiology, diagnosis, classification and the current 'standard' treatment, through to recent advances in our understanding of the cytogenetic and molecular underpinnings of the disease, such as the IDH2 mutation, and the future for tailored therapy. It will be useful to primary care providers, medical students, specialist nurses, junior doctors and allied healthcare professionals who want to develop a thorough grounding in our evolving understanding of AML and its treatment. Contents: • Epidemiology, pathophysiology and etiology • Diagnosis • Treatment • Supportive care • Prognosis and monitoring • Emerging treatments • Useful resources
Book Synopsis Fast Facts: Chronic Lymphocytic Leukemia by : Toby A Eyre
Download or read book Fast Facts: Chronic Lymphocytic Leukemia written by Toby A Eyre and published by Karger Medical and Scientific Publishers. This book was released on 2022-02-11 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic lymphocytic leukemia (CLL) is the most diagnosed leukemia in the Western world, accounting for approximately 25% of all new leukemia diagnoses. In recent years, remarkable progress has been made in our understanding of both the pathophysiology and genetics of CLL. While the disease generally affects older adults and initially follows an indolent course, cytogenetic and molecular profiling have helped to predict clinical outcomes. Greater prognostication, alongside the development of an increasing armamentarium of novel targeted therapies, has enabled us to provide more personalized management options for patients. 'Fast Facts: Chronic Lymphocytic Leukemia' covers the epidemiology, etiology, diagnosis and staging of the disease, and the molecular and genetic aspects that underpin treatment and prognosis. It provides a concise overview of treatment options, in both the front-line and relapsed/refractory settings, with particular focus on the novel targeted agents that have overcome many adverse prognostic factors, improving overall survival. Table of Contents: • Epidemiology and etiology • Molecular biology and genetics • Diagnosis, staging and prognosis • Management • Research directions
Download or read book Fast Facts written by William Blum and published by . This book was released on 2018 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Fast Facts: Acute Lymphoblastic Leukemia by : Bela Wrench
Download or read book Fast Facts: Acute Lymphoblastic Leukemia written by Bela Wrench and published by Karger Medical and Scientific Publishers. This book was released on 2022-06-30 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute lymphoblastic leukemia (ALL) is the most diagnosed childhood cancer worldwide. Although rare in adults, this aggressive cancer also shows a second smaller incidence peak in later middle age.
Modern genetic profiling techniques are providing a better understanding of the molecular biology of ALL, which, in turn, is leading to significant advances in diagnosis, prognostication and therapy selection. Ongoing refinement of risk-adapted frontline treatment protocols, use of novel targeted therapies and better supportive care are improving outcomes for patients with ALL.
Fast Facts: Acute Lymphoblastic Leukemia covers the epidemiology, etiology, diagnosis and classification of ALL as well as the measurement of minimal residual disease to determine prognosis. It provides guidance on frontline therapies and the treatment of relapsed and refractory ALL, including the use of newer targeted agents and the role of allogeneic stem-cell transplantation. Looking to the future, it also considers the approaches and refinements that are in development for ALL. Table of Contents:
Book Synopsis Fast Facts: Myeloproliferative Neoplasms by : Ruben A. Mesa
Download or read book Fast Facts: Myeloproliferative Neoplasms written by Ruben A. Mesa and published by Karger Medical and Scientific Publishers. This book was released on 2019 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presentation of the myeloproliferative neoplasms (MPNs) varies widely, and correct diagnosis and management can be challenging, and is becoming more complex as understanding of the underlying molecular basis for these disorders emerges. Appropriate management is increasingly informed by accurate risk stratification founded on understanding of cytogenetic and molecular markers, as well as the clinical presentation. 'Fast Facts: myeloproliferative neoplasms' focuses on the three most common chronic MPNs: * Essential thrombocythemia (ET) - characterized by increased platelet count * Polycythemia vera (PV) - characterized by excessive production of red blood cells * Primary myelofibrosis - a more severe and heterogenous disorder that may overlap with ET and PV but is commonly associated with anemia. Written by two leading experts in the field, Fast Facts: myeloproliferative neoplasms provides concise, up-to-date and practical guidance on the accurate diagnosis, risk stratification and management of these MPNs. It also provides key insights into our growing understanding of the underlying molecular and genetic basis of these disorders, and how this is informing risk stratification and management strategies. This concise handbook will be invaluable to clinicians, medical students, nurses, pharmacists and scientists in understanding and overcoming the everyday and rarer challenges associated with MPN.
Download or read book Fast Facts: Leucemia written by J. Loke and published by Karger Medical and Scientific Publishers. This book was released on 2019-11-28 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aunque la incidencia y prevalencia de leucemia está aumentando a nivel mundial, los avances en el diagnóstico y el tratamiento indican que las tasas de supervivencia también están aumentando. Comenzando con una descripción detallada de la hematopoyesis y lo que está mal en caso de la leucemia, esta guía concisa abarca todos los aspectos de los cuatro subtipos más frecuentes de la enfermedad: leucemia mieloide aguda (AML), leucemia linfoblástica aguda (ALL), leucemia mieloide crónica (CML) y leucemia linfocítica crónica (CLL). Este libro considera las causas y factores de riesgo para cada subtipo de leucemia, las pruebas diagnósticas iniciales y confirmatorias (incluyendo métodos de citogenética y genética molecular) y las opciones de tratamiento más recientes. Tanto los efectos de la enfermedad como los efectos adversos del tratamiento siguen representando un desafío complejo y se considera el abordaje multidisciplinario necesario para una atención de apoyo efectiva. Por último, se examinan las complicaciones urgentes que requieren atención de emergencia. Diseñado como una guía integral para enfermeras especializadas, médicos de atención primaria y residentes de hematología/oncología, este recurso ayudará a quienes no son especialistas a identificar la leucemia en etapas tempranas y proporciona una comprensión detallada de la patología y la base genética de la enfermedad, las opciones de tratamiento y los abordajes efectivos a la atención de urgencia y cuidados de apoyo.
Book Synopsis Fast Facts: Chronic Lymphocytic Leukemia by : Toby A. Eyre
Download or read book Fast Facts: Chronic Lymphocytic Leukemia written by Toby A. Eyre and published by Karger Medical and Scientific Publishers. This book was released on 2023-06-07 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic lymphocytic leukemia (CLL) is the most diagnosed leukemia in the Western world, accounting for approximately 25% of all new leukemia diagnoses. In recent years, remarkable progress has been made in our understanding of both the pathophysiology and genetics of CLL. While the disease generally affects older adults and initially follows an indolent course, cytogenetic and molecular profiling have helped to predict clinical outcomes. Greater prognostication, alongside the development of an increasing armamentarium of novel targeted therapies, has enabled us to provide more personalized management options for patients. Table of Contents • Epidemiology and etiology • Molecular biology and genetics • Diagnosis, staging and prognosis • Management • Research directions
Book Synopsis Fast Facts for Patients: Chronic Lymphocytic Leukemia by : Kathryn Huntley
Download or read book Fast Facts for Patients: Chronic Lymphocytic Leukemia written by Kathryn Huntley and published by Karger Medical and Scientific Publishers. This book was released on 2023-07-05 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic lymphocytic leukemia (CLL) is a slow-growing type of blood cancer and the most common form of leukemia in adults. CLL results in large numbers of abnormal B lymphocytes in the bone marrow and prevents the production of healthy blood cells. It is more commonly diagnosed in older people: almost 80% of cases are in people over 60 years old. Changes in chromosomes or genes in some patients affect how the disease develops and what treatment is prescribed. CLL cannot be completely cured but many people will have a normal lifespan and a good quality of life.
Book Synopsis Fast Facts: Treatment-Free Remission in Chronic Myeloid Leukemia by : Sandeep Potluri
Download or read book Fast Facts: Treatment-Free Remission in Chronic Myeloid Leukemia written by Sandeep Potluri and published by Karger Medical and Scientific Publishers. This book was released on 2021-01-26 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tyrosine kinase inhibitor (TKI) imatinib was the first treatment to specifically target cancer cells, rather than the relatively indiscriminate effects of conventional chemotherapy on any rapidly dividing cells. This concept of targeted treatment in cancer is one of the important advances in modern medicine in the last 30 years. Indeed, treatment with TKIs has transformed chronic myeloid leukemia (CML) from a cancer with a poor prognosis to one in which many patients can expect a normal lifespan. Success with the TKIs has prompted the question of whether it is desirable – or feasible – for patients to remain on treatment for long periods. While the TKIs are targeted, they are associated with considerable toxicity, and long-term treatment has important economic implications for health services and patients. Thus, the concept of treatment-free remission (TFR) has emerged for patients in deep clinical remission. Clinical research over the last decade has focused on whether treatment can be stopped, how to best monitor patients while off treatment, and how to intervene before a clinical relapse. As this research progresses, the tantalizing prospect of a cure for some patients seems increasingly feasible. This new Fast Facts title outlines this trail-blazing approach to the long-term management of patients living with CML in remission. It explains the concepts of molecular and hematologic relapse, the highly sensitive technologies that allow disease monitoring, and how TFR is best managed in practice. It is a concise educational resource, ideal for any healthcare professional involved in the treatment of patients with CML who wants to understand TFR, particularly clinical nurse specialists and pharmacists who increasingly help clinicians to run CML clinics. Table of Contents: • The concept of treatment-free remission • Measurement of disease burden • Clinical practice • Future directions
Book Synopsis Fast Facts : Acute Myeloid Leukemia by : William Blum
Download or read book Fast Facts : Acute Myeloid Leukemia written by William Blum and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This last year has seen the approval of the first targeted treatments for acute myeloid leukemia (AML) - following decades with no new developments and a poor prognosis for most patients with the disease. The new drugs reflect the remarkable progress that has been made in our understanding of the pathophysiology of AML and its underlying cytogenetic and molecular abnormalities - which differ not only between patients but also within a patient over time and with treatment. 'Fast Facts: Acute Myeloid Leukemia' provides a comprehensive yet concise foundation for understanding AML: from basic epidemiology, diagnosis, classification and the current 'standard' treatment, through to recent advances in our understanding of the cytogenetic and molecular underpinnings of the disease, such as the IDH2 mutation, and the future for tailored therapy. It will be useful to primary care providers, medical students, specialist nurses, junior doctors and allied healthcare professionals who want to develop a thorough grounding in our evolving understanding of AML and its treatment. Contents: • Epidemiology, pathophysiology and etiology • Diagnosis • Treatment • Supportive care • Prognosis and monitoring • Emerging treatments • Useful resources.
Book Synopsis Childhood Acute Lymphoblastic Leukemia by : Ajay Vora
Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
Book Synopsis Fast Facts: Lymphoma by : Chris Hatton
Download or read book Fast Facts: Lymphoma written by Chris Hatton and published by Karger Medical and Scientific Publishers. This book was released on 2018-10-16 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lymphoma affects all ages. Advances in diagnostic cellular and molecular techniques coupled with new treatment options are improving patient outcomes. This third edition of our bestselling 'Fast Facts: Lymphoma' distills the most important aspects of diagnosis and management into an up-to-date and highly accessible well-illustrated overview that includes: • a clear outline of the nature of lymphoma • the essentials of clinical presentation, biopsy and histology • a synopsis of current laboratory diagnostics, including immunophenotyping, cytogenetics and microarray technology, and updated to include the latest molecular genetic techniques • key aspects of staging and initial therapy • clearly illustrated overviews of the pathology, presentation, treatment and prognosis of each lymphoma subtype • new treatment options, including targeted biological therapies and chimeric antigen receptor T cells (CAR T cells) • a practical overview of supportive care for the complications of lymphoma. Written by three lymphoma experts from the UK and USA, 'Fast Facts: Lymphoma' gives an interesting international perspective to this challenging disease. Its clarity and colorful format make it a valuable resource for senior health professionals seeking an accessible update in this area of hemato-oncology, trainee doctors and specialist nurses who are new to it, and individuals affected by lymphoma and seeking more information. Contents: • Epidemiology • Cellular and molecular aspects • Presentation, biopsy and diagnostic laboratory techniques • Staging and general management principles • Aggressive B-cell lymphomas • Indolent B-cell lymphomas • T-cell and natural-killer cell lymphomas • Immunocompromised and HIV-positive patients • Hodgkin lymphoma • Treatment modalities • Supportive care
Author :Ailsa E. Gebbie Publisher :Karger Medical and Scientific Publishers ISBN 13 :1905832508 Total Pages :117 pages Book Rating :4.9/5 (58 download)
Book Synopsis Fast Facts: Contraception by : Ailsa E. Gebbie
Download or read book Fast Facts: Contraception written by Ailsa E. Gebbie and published by Karger Medical and Scientific Publishers. This book was released on 2009-02-01 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major roles of anyone working in sexual health is that of educator, and many people rely on well-informed healthcare professionals to help them choose the most appropriate method of contraception. This completely revised third edition of 'Fast Facts: Contraception', by two new authors of international renown, provides a concise and practical review of all the available contraceptive methods on the market in a highly readable well-illustrated format. Highlights of this comprehensive handbook include: • A commonsense approach to the contraception consultation • Fully updated information on recently licensed products • Discussion of the risks, benefits and contraindications for all contraceptive methods. 'Fast Facts: Contraception' is an invaluable resource that will help healthcare professionals and specialists offer a broader range of contraceptive methods along with appropriate advice on the most suitable options. Contents: • Choosing a contraceptive method • Combined hormonal contraception • Progestogen-only methods • Intrauterine devices and systems • Barrier methods • Emergency contraception • Female sterilization • Vasectomy and hormonal methods for men • Biologically based methods • Postpartum contraception • Useful resources
Author :Grapham P. Collins Publisher :Karger Medical and Scientific Publishers ISBN 13 :3318072990 Total Pages :188 pages Book Rating :4.3/5 (18 download)
Book Synopsis Fast Facts: Lymphoma by : Grapham P. Collins
Download or read book Fast Facts: Lymphoma written by Grapham P. Collins and published by Karger Medical and Scientific Publishers. This book was released on 2023-08-09 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lymphoma can be broadly defined as a cancer of mature lymphocytes. Our understanding of the biology of normal lymphocytes and lymphoma has grown at a tremendous pace, and this is now directly translating into changes in clinical practice. This became evident with the introduction of one of the first therapeutic monoclonal antibodies into cancer medicine, the CD20-directed antibody rituximab, which has led to significant benefit for patients with B-cell lymphomas. Since then, a raft of novel agents has entered clinical practice, including targeted small molecules, antibody-drug conjugates, bispecific antibodies, and chimeric antigen receptor (CAR) T cells. This new edition of 'Fast Facts: Lymphoma' has been updated to include recent changes in our understanding of lymphoma biology as well as improvements in diagnostics and therapeutics.
Book Synopsis Prognosis in Advanced Cancer by : Paul Glare
Download or read book Prognosis in Advanced Cancer written by Paul Glare and published by OUP Oxford. This book was released on 2008-03-20 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Predicting survival and other outcomes is increasingly being recognized as an important skill for palliative care doctors and nurses, oncologists, and other healthcare professionals who treat patients with advanced cancer. Accurate prognosis is essential if we are to offer quality of care and 'a good death', as well as to aid decision-making. There is much prognostic information available that is scattered throughout the palliative care and oncological literature but this is the first time it has been gathered systematically in one place. Glare and Christakis, leaders in the field of prognosis, bring together a team of international contributors from across the fields of palliative care and oncology. This comprehensive but practical guide begins with the principles of prognostication, including formulating the prediction and then communicating it. Topics such as statistical issues, evidence-based medicine, and the ethics of prognostication are also covered. The second section addresses prognostication in 15 specific cancer sites once they have reached the advanced stage, following a standard template for consistency and easy access to the key information. The third section deals with prognostication in patients with a variety of common clinical conditions at the end of life, such as bowel obstruction, hypercalcaemia, and brain metastases. In addition, survival curves are provided within each chapter, palliative care conditions are examined for the first time, and a summary table of long and short term prognosis ensures this book remains practical.
