Fast Facts: Leukemia

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318069965
Total Pages : 138 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Leukemia by : Justin Loke

Download or read book Fast Facts: Leukemia written by Justin Loke and published by Karger Medical and Scientific Publishers. This book was released on 2022-02-22 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leukemia is a hematologic malignancy arising from hematopoietic stem cells (HSCs) in the bone marrow. Starting with a detailed description of hematopoiesis and what goes wrong in leukemia, this concise guide covers all aspects of the four most common subtypes of the disease. Although the incidence and prevalence of leukemia are rising worldwide, survival rates are also increasing. However, both the effects of the disease and the adverse effects of treatment remain complex challenges. Yet, as our understanding of the molecular landscape increases, therapeutic options are becoming more personalized. This revised and updated second edition of 'Fast Facts: Leukemia' addresses the causes and risk factors for each subtype of leukemia, the initial and confirmatory diagnostic tests, and the latest treatment options. Designed as a comprehensive primer for physician assistants, nurse practitioners, primary care providers, oncology nurses, hematology/ oncology trainees and pharmacists, this resource will help the non-specialist and those in training to identify leukemia early and provide a thorough understanding of the pathology and genetic basis of the disease, treatment options, and effective approaches to emergency and supportive care. Table of Contents: • Understanding blood and its components • What is leukemia? • Epidemiology, etiology and risk factors • Diagnosis • Staging and general management • Supportive care • Emergencies in leukemia

Fast Facts: Acute Lymphoblastic Leukemia

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318069779
Total Pages : 108 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Acute Lymphoblastic Leukemia by : Bela Wrench

Download or read book Fast Facts: Acute Lymphoblastic Leukemia written by Bela Wrench and published by Karger Medical and Scientific Publishers. This book was released on 2022-06-30 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute lymphoblastic leukemia (ALL) is the most diagnosed childhood cancer worldwide. Although rare in adults, this aggressive cancer also shows a second smaller incidence peak in later middle age.

Modern genetic profiling techniques are providing a better understanding of the molecular biology of ALL, which, in turn, is leading to significant advances in diagnosis, prognostication and therapy selection. Ongoing refinement of risk-adapted frontline treatment protocols, use of novel targeted therapies and better supportive care are improving outcomes for patients with ALL.

Fast Facts: Acute Lymphoblastic Leukemia covers the epidemiology, etiology, diagnosis and classification of ALL as well as the measurement of minimal residual disease to determine prognosis. It provides guidance on frontline therapies and the treatment of relapsed and refractory ALL, including the use of newer targeted agents and the role of allogeneic stem-cell transplantation. Looking to the future, it also considers the approaches and refinements that are in development for ALL. Table of Contents:

  • Epidemiology, pathophysiology and etiology
  • Diagnosis
  • Prognostic factors
  • Treatment
  • Relapsed or refractory ALL
  • Future directions
  • Fast Facts: Chronic Lymphocytic Leukemia

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 3318069736
    Total Pages : 74 pages
    Book Rating : 4.3/5 (18 download)

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    Book Synopsis Fast Facts: Chronic Lymphocytic Leukemia by : Toby A Eyre

    Download or read book Fast Facts: Chronic Lymphocytic Leukemia written by Toby A Eyre and published by Karger Medical and Scientific Publishers. This book was released on 2022-02-11 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic lymphocytic leukemia (CLL) is the most diagnosed leukemia in the Western world, accounting for approximately 25% of all new leukemia diagnoses. In recent years, remarkable progress has been made in our understanding of both the pathophysiology and genetics of CLL. While the disease generally affects older adults and initially follows an indolent course, cytogenetic and molecular profiling have helped to predict clinical outcomes. Greater prognostication, alongside the development of an increasing armamentarium of novel targeted therapies, has enabled us to provide more personalized management options for patients. 'Fast Facts: Chronic Lymphocytic Leukemia' covers the epidemiology, etiology, diagnosis and staging of the disease, and the molecular and genetic aspects that underpin treatment and prognosis. It provides a concise overview of treatment options, in both the front-line and relapsed/refractory settings, with particular focus on the novel targeted agents that have overcome many adverse prognostic factors, improving overall survival. Table of Contents: • Epidemiology and etiology • Molecular biology and genetics • Diagnosis, staging and prognosis • Management • Research directions

    Fast Facts for Patients: Chronic Lymphocytic Leukemia

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    Author :
    Publisher :
    ISBN 13 : 9783318072273
    Total Pages : 0 pages
    Book Rating : 4.0/5 (722 download)

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    Book Synopsis Fast Facts for Patients: Chronic Lymphocytic Leukemia by : Kathryn Huntley

    Download or read book Fast Facts for Patients: Chronic Lymphocytic Leukemia written by Kathryn Huntley and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic lymphocytic leukemia (CLL) is a slow-growing type of blood cancer and the most common form of leukemia in adults. CLL results in large numbers of abnormal B lymphocytes in the bone marrow and prevents the production of healthy blood cells. It is more commonly diagnosed in older people: almost 80% of cases are in people over 60 years old. Changes in chromosomes or genes in some patients affect how the disease develops and what treatment is prescribed. CLL cannot be completely cured but many people will have a normal lifespan and a good quality of life.

    Fast Facts: Leucemia

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 3318066338
    Total Pages : 140 pages
    Book Rating : 4.3/5 (18 download)

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    Book Synopsis Fast Facts: Leucemia by : J. Loke

    Download or read book Fast Facts: Leucemia written by J. Loke and published by Karger Medical and Scientific Publishers. This book was released on 2019-11-28 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aunque la incidencia y prevalencia de leucemia está aumentando a nivel mundial, los avances en el diagnóstico y el tratamiento indican que las tasas de supervivencia también están aumentando. Comenzando con una descripción detallada de la hematopoyesis y lo que está mal en caso de la leucemia, esta guía concisa abarca todos los aspectos de los cuatro subtipos más frecuentes de la enfermedad: leucemia mieloide aguda (AML), leucemia linfoblástica aguda (ALL), leucemia mieloide crónica (CML) y leucemia linfocítica crónica (CLL). Este libro considera las causas y factores de riesgo para cada subtipo de leucemia, las pruebas diagnósticas iniciales y confirmatorias (incluyendo métodos de citogenética y genética molecular) y las opciones de tratamiento más recientes. Tanto los efectos de la enfermedad como los efectos adversos del tratamiento siguen representando un desafío complejo y se considera el abordaje multidisciplinario necesario para una atención de apoyo efectiva. Por último, se examinan las complicaciones urgentes que requieren atención de emergencia. Diseñado como una guía integral para enfermeras especializadas, médicos de atención primaria y residentes de hematología/oncología, este recurso ayudará a quienes no son especialistas a identificar la leucemia en etapas tempranas y proporciona una comprensión detallada de la patología y la base genética de la enfermedad, las opciones de tratamiento y los abordajes efectivos a la atención de urgencia y cuidados de apoyo.

    Childhood Acute Lymphoblastic Leukemia

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    Author :
    Publisher : Springer
    ISBN 13 : 3319397087
    Total Pages : 345 pages
    Book Rating : 4.3/5 (193 download)

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    Book Synopsis Childhood Acute Lymphoblastic Leukemia by : Ajay Vora

    Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.

    Fast Facts: Leukemia

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 3318069493
    Total Pages : 138 pages
    Book Rating : 4.3/5 (18 download)

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    Book Synopsis Fast Facts: Leukemia by : J. Loke

    Download or read book Fast Facts: Leukemia written by J. Loke and published by Karger Medical and Scientific Publishers. This book was released on 2022-03-02 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leukemia is a hematologic malignancy arising from hematopoietic stem cells (HSCs) in the bone marrow. Starting with a detailed description of hematopoiesis and what goes wrong in leukemia, this concise guide covers all aspects of the four most common subtypes of the disease. Although the incidence and prevalence of leukemia are rising worldwide, survival rates are also increasing. However, both the effects of the disease and the adverse effects of treatment remain complex challenges. Yet, as our understanding of the molecular landscape increases, therapeutic options are becoming more personalized. This revised and updated second edition of 'Fast Facts: Leukemia' addresses the causes and risk factors for each subtype of leukemia, the initial and confirmatory diagnostic tests, and the latest treatment options. Designed as a comprehensive primer for physician assistants, nurse practitioners, primary care providers, oncology nurses, hematology/ oncology trainees and pharmacists, this resource will help the non-specialist and those in training to identify leukemia early and provide a thorough understanding of the pathology and genetic basis of the disease, treatment options, and effective approaches to emergency and supportive care. Table of Contents: • Understanding blood and its components • What is leukemia? • Epidemiology, etiology and risk factors • Diagnosis • Staging and general management • Supportive care • Emergencies in leukemia

    Hematology

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    Author :
    Publisher :
    ISBN 13 : 9780443066283
    Total Pages : 2821 pages
    Book Rating : 4.0/5 (662 download)

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    Book Synopsis Hematology by : Ronald Hoffman

    Download or read book Hematology written by Ronald Hoffman and published by . This book was released on 2005 with total page 2821 pages. Available in PDF, EPUB and Kindle. Book excerpt:

    Fast Facts: Acute Myeloid Leukemia

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 1910797596
    Total Pages : 90 pages
    Book Rating : 4.9/5 (17 download)

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    Book Synopsis Fast Facts: Acute Myeloid Leukemia by : William Blum

    Download or read book Fast Facts: Acute Myeloid Leukemia written by William Blum and published by Karger Medical and Scientific Publishers. This book was released on 2018-05-14 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: This last year has seen the approval of the first targeted treatments for acute myeloid leukemia (AML) - following decades with no new developments and a poor prognosis for most patients with the disease. The new drugs reflect the remarkable progress that has been made in our understanding of the pathophysiology of AML and its underlying cytogenetic and molecular abnormalities - which differ not only between patients but also within a patient over time and with treatment. 'Fast Facts: Acute Myeloid Leukemia' provides a comprehensive yet concise foundation for understanding AML: from basic epidemiology, diagnosis, classification and the current 'standard' treatment, through to recent advances in our understanding of the cytogenetic and molecular underpinnings of the disease, such as the IDH2 mutation, and the future for tailored therapy. It will be useful to primary care providers, medical students, specialist nurses, junior doctors and allied healthcare professionals who want to develop a thorough grounding in our evolving understanding of AML and its treatment. Contents: • Epidemiology, pathophysiology and etiology • Diagnosis • Treatment • Supportive care • Prognosis and monitoring • Emerging treatments • Useful resources

    Pediatric Acute Lymphoblastic Leukemia

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    Author :
    Publisher : Springer Nature
    ISBN 13 : 9811505489
    Total Pages : 168 pages
    Book Rating : 4.8/5 (115 download)

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    Book Synopsis Pediatric Acute Lymphoblastic Leukemia by : Motohiro Kato

    Download or read book Pediatric Acute Lymphoblastic Leukemia written by Motohiro Kato and published by Springer Nature. This book was released on 2019-11-26 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses key aspects of childhood acute lymphoblastic leukemia (ALL), presenting the latest research on the biology and treatment of the disease and related issues. The cure rate for ALL has improved dramatically due to advances such as supportive care, treatment stratification based on relapse risk, and the optimization of treatment regimens. Gathering contributions by eminent scholars Pediatric Acute Lymphoblastic Leukemia is a valuable resource for pediatric hematologists as well as for medical students, interns, residents and fellows. It not only offers comprehensive insights, but also provides a springboard for future research.

    Fast Facts: Measurable Residual Disease

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 331806825X
    Total Pages : 33 pages
    Book Rating : 4.3/5 (18 download)

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    Book Synopsis Fast Facts: Measurable Residual Disease by : J. Loke

    Download or read book Fast Facts: Measurable Residual Disease written by J. Loke and published by Karger Medical and Scientific Publishers. This book was released on 2021-01-26 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conventional methods of detecting disease remission in cancers such as leukemia rely on microscopic analysis of tissue samples. Measurable (or minimal) residual disease (MRD) describes the presence of disease beyond the levels of sensitivity afforded by microscopy. Fast Facts: Measurable Residual Disease describes what is meant by MRD, the opportunities and challenges afforded by its identification and the advantages and disadvantages of the methods used for its detection. Specific examples are given to illustrate the implications of detecting MRD in different disease scenarios, with emphasis on acute myeloid and lymphoblastic leukemias. With the recognition and monitoring of MRD likely to play an increasingly important role in disease prognosis and subsequent treatment direction, this accessible resource is ideal for any healthcare professional wanting to know more about this exciting and fast-moving area. Table of Contents: • What is measurable residual disease? • How is MRD measured? • What is the significance of MRD?

    Handbook of Acute Leukemia

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    Author :
    Publisher : Springer
    ISBN 13 : 3319267728
    Total Pages : 100 pages
    Book Rating : 4.3/5 (192 download)

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    Book Synopsis Handbook of Acute Leukemia by : Wolfgang Hiddemann

    Download or read book Handbook of Acute Leukemia written by Wolfgang Hiddemann and published by Springer. This book was released on 2016-11-14 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the key developments in both acute lymphocytic leukemia and acute myeloid leukemia with a comprehensive guide to the epidemiology, pathogenesis, etiology, clinical manifestations, classification, diagnosis, and staging as well as the most recent developments in the therapeutic landscape for acute leukemia. The Handbook of Acute Leukemia offers readers a key resource into the future outlook for patients with leukemia and is edited and authored by internationally renowned experts in the field. Leukemia is cancer of the white blood cells and acute leukemia means the condition progresses rapidly and aggressively, requiring immediate treatment. Acute leukemia is classified according to the type of white blood cells that are affected: either lymphocytes and myeloid cells.

    Fast Facts: Measurable Residual Disease

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 3318068241
    Total Pages : 33 pages
    Book Rating : 4.3/5 (18 download)

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    Book Synopsis Fast Facts: Measurable Residual Disease by : Justin Loke

    Download or read book Fast Facts: Measurable Residual Disease written by Justin Loke and published by Karger Medical and Scientific Publishers. This book was released on 2021-01-26 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conventional methods of detecting disease remission in cancers such as leukemia rely on microscopic analysis of tissue samples. Measurable (or minimal) residual disease (MRD) describes the presence of disease beyond the levels of sensitivity afforded by microscopy. Fast Facts: Measurable Residual Disease describes what is meant by MRD, the opportunities and challenges afforded by its identification and the advantages and disadvantages of the methods used for its detection. Specific examples are given to illustrate the implications of detecting MRD in different disease scenarios, with emphasis on acute myeloid and lymphoblastic leukemias. With the recognition and monitoring of MRD likely to play an increasingly important role in disease prognosis and subsequent treatment direction, this accessible resource is ideal for any healthcare professional wanting to know more about this exciting and fast-moving area. Table of Contents: • What is measurable residual disease? • How is MRD measured? • What is the significance of MRD?

    Fast Facts: Lymphoma

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 1908541776
    Total Pages : 142 pages
    Book Rating : 4.9/5 (85 download)

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    Book Synopsis Fast Facts: Lymphoma by : Chris Hatton

    Download or read book Fast Facts: Lymphoma written by Chris Hatton and published by Karger Medical and Scientific Publishers. This book was released on 2014-10-31 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hodgkin lymphoma and the many different subtypes of non-Hodgkin lymphoma (NHL) have different responses to treatment, so accurate diagnosis and a rational approach to management are essential. 'Fast Facts: Lymphoma' distills the most important aspects of the diagnosis and management of these complex disorders into a highly accessible well-illustrated summary of the key facts. This fully updated second edition provides: • a clear outline of the nature of lymphoma • the essentials of clinical presentation, biopsy and basic histology • the latest laboratory diagnostics, including immunophenotyping, cytogenetics and microarray technology • key aspects of staging and initial therapy • superbly illustrated overviews of the pathology, presentation, treatment and prognosis of each lymphoma subtype • new treatment options, including targeted biological therapies • a practical overview of supportive care for the complications of lymphoma Written by three experts in the field from the UK and USA, 'Fast Facts: Lymphoma' applies an international perspective to this challenging disease in a unique format within the context of clinical practice. It is a valuable resource for trainee doctors and specialist nurses working in the field of hemato-oncology. It will also be of interest to the inquiring patient or carer who wishes to know more about lymphoma. Contents: • Epidemiology • Cellular and molecular aspects • Presentation, biopsy and diagnostic laboratory techniques • Staging and general management principles • Aggressive B-cell lymphomas • Indolent B-cell lymphomas • T-cell and natural-killer cell lymphomas • Immunocompromised and HIV-positive patients • Hodgkin lymphoma • Treatment modalities • Supportive care

    Fast Facts: Lymphoma

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 1910797952
    Total Pages : 161 pages
    Book Rating : 4.9/5 (17 download)

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    Book Synopsis Fast Facts: Lymphoma by : C. Hatton

    Download or read book Fast Facts: Lymphoma written by C. Hatton and published by Karger Medical and Scientific Publishers. This book was released on 2018-10-16 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lymphoma affects all ages. Advances in diagnostic cellular and molecular techniques coupled with new treatment options are improving patient outcomes. This third edition of our bestselling 'Fast Facts: Lymphoma' distills the most important aspects of diagnosis and management into an up-to-date and highly accessible well-illustrated overview that includes: • a clear outline of the nature of lymphoma • the essentials of clinical presentation, biopsy and histology • a synopsis of current laboratory diagnostics, including immunophenotyping, cytogenetics and microarray technology, and updated to include the latest molecular genetic techniques • key aspects of staging and initial therapy • clearly illustrated overviews of the pathology, presentation, treatment and prognosis of each lymphoma subtype • new treatment options, including targeted biological therapies and chimeric antigen receptor T cells (CAR T cells) • a practical overview of supportive care for the complications of lymphoma. Written by three lymphoma experts from the UK and USA, 'Fast Facts: Lymphoma' gives an interesting international perspective to this challenging disease. Its clarity and colorful format make it a valuable resource for senior health professionals seeking an accessible update in this area of hemato-oncology, trainee doctors and specialist nurses who are new to it, and individuals affected by lymphoma and seeking more information. Contents: • Epidemiology • Cellular and molecular aspects • Presentation, biopsy and diagnostic laboratory techniques • Staging and general management principles • Aggressive B-cell lymphomas • Indolent B-cell lymphomas • T-cell and natural-killer cell lymphomas • Immunocompromised and HIV-positive patients • Hodgkin lymphoma • Treatment modalities • Supportive care

    Fast Facts: Treatment-Free Remission in Chronic Myeloid Leukemia

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 3318068349
    Total Pages : 54 pages
    Book Rating : 4.3/5 (18 download)

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    Book Synopsis Fast Facts: Treatment-Free Remission in Chronic Myeloid Leukemia by : S. Potluri

    Download or read book Fast Facts: Treatment-Free Remission in Chronic Myeloid Leukemia written by S. Potluri and published by Karger Medical and Scientific Publishers. This book was released on 2021-01-26 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tyrosine kinase inhibitor (TKI) imatinib was the first treatment to specifically target cancer cells, rather than the relatively indiscriminate effects of conventional chemotherapy on any rapidly dividing cells. This concept of targeted treatment in cancer is one of the important advances in modern medicine in the last 30 years. Indeed, treatment with TKIs has transformed chronic myeloid leukemia (CML) from a cancer with a poor prognosis to one in which many patients can expect a normal lifespan. Success with the TKIs has prompted the question of whether it is desirable – or feasible – for patients to remain on treatment for long periods. While the TKIs are targeted, they are associated with considerable toxicity, and long-term treatment has important economic implications for health services and patients. Thus, the concept of treatment-free remission (TFR) has emerged for patients in deep clinical remission. Clinical research over the last decade has focused on whether treatment can be stopped, how to best monitor patients while off treatment, and how to intervene before a clinical relapse. As this research progresses, the tantalizing prospect of a cure for some patients seems increasingly feasible. This new Fast Facts title outlines this trail-blazing approach to the long-term management of patients living with CML in remission. It explains the concepts of molecular and hematologic relapse, the highly sensitive technologies that allow disease monitoring, and how TFR is best managed in practice. It is a concise educational resource, ideal for any healthcare professional involved in the treatment of patients with CML who wants to understand TFR, particularly clinical nurse specialists and pharmacists who increasingly help clinicians to run CML clinics. Table of Contents: • The concept of treatment-free remission • Measurement of disease burden • Clinical practice • Future directions

    Fast Facts: CAR T-Cell Therapy

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    Author :
    Publisher : Karger Medical and Scientific Publishers
    ISBN 13 : 3318067415
    Total Pages : 71 pages
    Book Rating : 4.3/5 (18 download)

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    Book Synopsis Fast Facts: CAR T-Cell Therapy by : Richard J. Buka

    Download or read book Fast Facts: CAR T-Cell Therapy written by Richard J. Buka and published by Karger Medical and Scientific Publishers. This book was released on 2021-02-28 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chimeric antigen receptor (CAR) T cells are genetically engineered immune cells that can seek out and destroy cancer cells. The results from their use in cancer immunotherapy have been very promising, but treatment is often associated with frequent, serious short-term toxicities. 'Fast Facts: CAR-T Therapy' explains what CAR T cells are and how they were developed, discusses the results of clinical trials and the management of toxicities, and outlines future improvements and applications. It is ideal reading for any healthcare professional wanting to know more about this exciting therapeutic field. Table of Contents: • CAR T cells • Clinical application • Practical aspects • Future directions