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Experimental Hematology Today 1989
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Book Synopsis Experimental Hematology Today—1989 by : Norbert C. Gorin
Download or read book Experimental Hematology Today—1989 written by Norbert C. Gorin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental Hematology Today - 1989 comprises selected papers presented at the 18th Annual Meeting of the International Society for Experimental Hematology, July 16-20, 1989, Paris, France. Four major areas of research are explored: present aspects of stem cell transplantation; control of hemopoiesis; hemopoiesis in malignancies; and gene transfer. The role of autologous bone marrow transplantation in acute leukemia and in Hodgkin lymphoma, properties of the murine interleukin-3 receptor, effects of Ubenimex on proliferation and differentiation of human bone marrow cells and leukemic cell lines, immune system stimulation for the therapy of advanced stage neuroblastoma, and retro-viral gene transfer of human adenosine deaminase into hematopoietic cells are some of the topics considered. ^ ***BUCHHÄNDLERTEXT-E*** Selected papers from the 18th Annual Meeting of the International Society for Experimental Hematology. The proceedings are published annually and report on the latest experimental and clinical research.
Book Synopsis Experimental Hematology Today—1988 by : Siegmund J. Baum
Download or read book Experimental Hematology Today—1988 written by Siegmund J. Baum and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental Hematology Today - 1988 presents the latest results of research reflecting the diverse interests of basic and clinical hematologists. The major areas explored are hematopoietic regulation by cytokines; hematopoietic cellular growth regulation, with emphasis on the interaction of stromal with hematopoietic stem and progenitor cells; granulopoietic regulators; gene transfers into hematopoietic progenitor cells; leukemogenesis; and bone marrow transplantation. All chapters report on research or clinical findings of the past year.
Book Synopsis Bone Marrow Processing and Purging by : Adrian P. Gee
Download or read book Bone Marrow Processing and Purging written by Adrian P. Gee and published by CRC Press. This book was released on 2020-11-25 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Marrow Processing and Purging: A Practical Guide provides an up-to-date practical guide to the major ex vivo procedures associated with bone marrow transplantation. Previously, this information was communicated primarily by word of mouth; now experts in the field present detailed descriptions and evaluations of methods for marrow harvesting, evaluation (including tumor infiltration, flow cytometric analysis, and colony assays), comparative methods for automated nucleated cell separation and enumeration, tumor cell purging, T cell depletion, stem cell selection, gene transfer, and cytopreservation. Special sections address quality control and FDA regulations. The book provides a unique information source intended for clinicians, researchers, technical staff, transplant nurses, and medical students involved in this rapidly expanding area of medicine.
Book Synopsis Published Scientific Papers of the National Institutes of Health by : National Institutes of Health (U.S.).
Download or read book Published Scientific Papers of the National Institutes of Health written by National Institutes of Health (U.S.). and published by . This book was released on 1990 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the broad outline of NIH organizational structure, theprofessional staff, and their scientific and technical publications covering work done at NIH.
Download or read book Recombinant DNA Research written by and published by . This book was released on 1995 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Microbial Infections by : Herman Friedman
Download or read book Microbial Infections written by Herman Friedman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is based on the Proceedings of the International Conference on "Microbial Infections: Role of Biological Response Modifiers" held in Tampa, FL, May 29-31, 1991. The major purpose of this conference was to bring together in one forum prominent investigators from around the world studying a variety of microbial pathogens, including bacteria, viruses, and fungi, and the effects of biological response modifiers (BRM) on the immune response to these microorganisms. BRM have been widely utilized in the area of antitumor resistance and include not only experimental tumor cell vaccines, but also biologically active substances such as cytokines, i. e. , interferons, tumor necrosis factor, and interleukins, as well as products from bacteria which influence host resistance mechanisms. It is the belief of the organizers of this Conference that it was very timely to discuss in detail BRMs as they impact on microbial infections per se. It is now widely accepted that immunocompromised individuals, including those exposed to immunosuppressive substances such as antimetabolites used for chemothera py of malignancies, or infectious agents, such as the human immunodeficiency virus and other viruses which depress the immune response and, in turn, affect a host so as to become highly susceptible to opportunistic microorganisms, benefit from BRM stimulation of their immune system. A wide variety of immunomodulators are now being studied in terms of treating infectious diseases, as well as malignancy and autoimmune diseases.
Download or read book Gene Therapeutics written by Jon A. Wolff and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the first half century of genetics, coinciding with the first half of this cen tury, geneticists dreamt of the repair of genetic disease by altering or replacing defective genes. H. J. Muller wrote of the great advantages of mutations, "nanoneedles" in his apt term, for delicately probing physiological and chemical processes. In the same spirit, genes could be used to provide treatments of needle point delicacy. Yet, during this period no realistic possibility appeared; it remained but a dream. The situation changed abruptly at the half century. Microbial genetics and its offshoot, cell culture genetics, provided the route. Pneumococcus transformation showed that exogenous DNA could become a permanent part of the genome; yet attempts to reproduce this in animals produced a few tantalizing hints of success, but mostly failures. Transduction, using a virus as mediator, offered a better op portunity. The fITSt reproducible in vivo gene therapy in a whole animal came in 1981. This was in Drosophila, with a transposable element as carrier. Flies were "cured" of a mutant eye color by incorporation of the normal allele, and the effect was transmissible, foreshadowing not only somatic, but germ line gene therapy. At the same time, retroviruses carrying human genes were found to be ex tremely efficient in transferring their contents to the chromosomes of cultured cells.
Book Synopsis Realm of Tolerance by : Pavol Ivanyi
Download or read book Realm of Tolerance written by Pavol Ivanyi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Any professional concerned with immunology will be interested in this book dedicated to the memory of Milan Hasek, former director of the Prague Institute of Experimental Biology and Genetics. Prof. Hasek was a congenial scientist and most amiable person - a personal friend of almost all leading immunologists around the world. He was displaced from his post of director in 1970, yet had a lasting impact upon his students and the group known as the Prague School of Immunogenetics. The topics covered in the contributions range from tolerance, immune network, and immunogenetics to the immunology of bacterial and viral infections. They are written by 27 of Prof. Hasek's former co-workers who emigrated to western countries around or after 1968 and became well-known and distinguished scientists in the field. The papers include their personal reflections of the Prague Institute, their impressions upon arriving abroad and their interesting experimental work since then. The book also provides a complete bibliography of their publications after leaving Czechoslovakia.
Book Synopsis Medical and Health Care Books and Serials in Print by :
Download or read book Medical and Health Care Books and Serials in Print written by and published by . This book was released on 1997 with total page 1680 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Leukemias written by J. Fleischer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current problems in research and treatment of leukemias as discussed at the symposium of the International Society of Haematology on leukemias in Dresden (Germany) are dealt with in detail in this volume. The characterization of leukemic cells and the evaluation of their function are themes, with the first hints emerging of the possibility of relating them to the intensity of treatment required. The cytokines, responsible for cooperation between cells, are also of great importance, and the beginnings of therapeutic applications can be discerned here. Not only are the cytokines themselves very interesting, but also the application of cells producing cytokines according to the range of macrophages found. The emphasis on cell-to-cell relationship is thus a main topic of the book. Of course, other treatment such as bone marrow transplantation and interferon therapy play an important part, too, and the latest results of chemotherapy are reported. A further essential area covered is the diagnosis and therapy of chronic leukemic diseases, the inclusion of which suitably rounds off the book. I am very grateful to the out standing specialists from both the West and the East who contributed to the symposium and this book: an important sign of collaboration and integration for the future.
Book Synopsis Negative Regulation of Hematopoiesis by : Martine Guigon
Download or read book Negative Regulation of Hematopoiesis written by Martine Guigon and published by John Libbey Eurotext. This book was released on 1993 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an update on the inhibitory mechanisms involved in the various steps of hematopoietic stem cell proliferation and differentiation. The authors report the latest research advances, factors that control the cell cycle, receptors function, molecular approaches, the in vivo and in vitro effects of several inhibitors, the inhibition of hematopoiesis by viruses, protecting the bone marrow. The book contains the latest results published by the best international specialists and will be fascinating reading for all those interested in this subject.
Book Synopsis Textbook of Malignant Haematology by : Laurent Degos
Download or read book Textbook of Malignant Haematology written by Laurent Degos and published by CRC Press. This book was released on 1999-01-01 with total page 972 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a concise overview of malignant haematology, including reviews of cell and molecular biology, and implications for new trends in treatment.
Book Synopsis Novel Chemotherapeutic Agents: Preactivation in the Treatment of Cancer and AIDS by : Kirpal S. Gulliya
Download or read book Novel Chemotherapeutic Agents: Preactivation in the Treatment of Cancer and AIDS written by Kirpal S. Gulliya and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about a discovery termed "preactivation" that is considered a major breakthrough in photodynamic therapy and in drug development. The process of preactivation generates previously unknown chemotherapeutic agents that are not only effective against malignancies and viral infections, but are also easily tolerated.
Book Synopsis Virginia Union List of Biomedical Serials by :
Download or read book Virginia Union List of Biomedical Serials written by and published by . This book was released on 1997 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Interleukin-2 and Killer Cells in Cancer by : Eva Lotzova
Download or read book Interleukin-2 and Killer Cells in Cancer written by Eva Lotzova and published by CRC Press. This book was released on 2018-02-01 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first-and only-publication available which provides the most recent information in this particular field of biomedicine. Interleukin-2 (IL-2) and IL-2 activated killer cells have been shown to have a potential in the treatment of a variety of human malignant diseases. This work comprehensively summarizes basic aspects of IL-2 as well as its clinical application, therefore making all these aspects easily accessible to the readers. Because of the clinical significance of this molecule in the treatment of cancer, the basic and clinical investigations in the IL-2 field are rapidly expanding, together with the interest of the scientific and medical community. This book is an excellent educational and teaching tool for scientists, clinicians, and students. Those who already have expertise in research in the IL-2 area will find this reference indispensible.
Download or read book Proceedings in Print written by and published by . This book was released on 1990 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hematopoiesis written by Leonard I. Zon and published by Oxford University Press. This book was released on 2001-04-12 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hematopoiesis, or the process of blood formation, has been extensively studied at both basic and clinical levels. Human diseases such as thalassemia, immunodeficiency, and leukemia represent defects in this process. Approaches to treat these disorders have required a basic understanding of the biology of blood cells. For instance, hemapoietic stem cell replacement or bone marrow transplantation has been used to ameliorate disease. This volume focuses on hematopoiesis at a cellular and molecular level, and establishes the basis for clinical manipulation of hematopoietic cells for therapeutic benefit. In Part I, the cellular characteristics of progenitors and stem cells are explored. Emphasis is placed on purification of stem cells and both in vitro and in vivo assays. The regulation of normal and leukemis stem cells is illustrated. An excellent discussion of potential use of these cells for gene therapy concludes this section. Hemapoiesis is easily studied during embryogenesis. Part II develops the concept of the waves of hemapoiesis during development. Comparative hematology is making a major comeback as a field in the 1990's. One hope is that general principles of hematopoiesis will be established by studying many models and systems. Part III delves into critical factors that regulate hematopoiesis, including both intracellular and extracellular signals. Part IV and V describe lineage programs for myeloid and lymphoid lineages. These chapters are meant to be illustrative of the different cell fates, but are not exhaustive. Part VI examines the genetics of hematopoisis, particularly in animal models. The hematopoietic system is in constant contact with stromal cells and endothelial cells during development and in the adult. Evidence suggests that endothelial cells and blood cells may arise from a common progenitor, the hemangioblast. Part VII and VIII discuss the stromal and endothelial cells with the emphasis on their interaction with hematopoietic cells.
