Experimental and Clinical Effects of L-Asparaginase

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Publisher : Springer Science & Business Media
ISBN 13 : 3642999840
Total Pages : 390 pages
Book Rating : 4.6/5 (429 download)

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Book Synopsis Experimental and Clinical Effects of L-Asparaginase by : E. Grundmann

Download or read book Experimental and Clinical Effects of L-Asparaginase written by E. Grundmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Experimental and Clinical Effects of L-asparaginase

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Publisher :
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Experimental and Clinical Effects of L-asparaginase by : H. F. Oettgen

Download or read book Experimental and Clinical Effects of L-asparaginase written by H. F. Oettgen and published by . This book was released on 1970 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Resistance in Leukemia and Lymphoma III

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306460555
Total Pages : 664 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis Drug Resistance in Leukemia and Lymphoma III by : G.J.L. Kaspers

Download or read book Drug Resistance in Leukemia and Lymphoma III written by G.J.L. Kaspers and published by Springer Science & Business Media. This book was released on 1999-09-30 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular drug resistance is a major limitation to the success of chemotherapy of leu kemia and lymphoma. The importance of this has now been recognized by both clinicians and scientists. It is of utmost importance to bridge the gap between laboratory and clinic in this field of research. This is the main purpose of the series of International Symposia on Drug Resistance in Leukemia and Lymphoma. These are held every three years in Am sterdam, The Netherlands, since 1992. This book contains the proceedings of the third of these meetings, organised in 1998. The book covers all important aspects of drug resistance in leukemia and lymphoma, both in the form of extensive reviews as in manuscripts describing original data. General mechanisms of resistance are discussed, including the drug resistance related proteins p glycoprotein, MRP (multi-drug resistance protein) and LRP (lung resistance protein), and the role of glutathione and glutathione-S-transferases. Moreover, more drug type-specific mechanisms of resistance are a topic, such as for glucocorticoids and antifolates. Much in formation is provided on apoptosis and its regulators, and on the results of cell culture drug resistance assays. Several papers focus on the modulation or circumvention of drug resistance.

Antineoplastic and Immunosuppressive Agents

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Publisher : Springer Science & Business Media
ISBN 13 : 3642658067
Total Pages : 1100 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Antineoplastic and Immunosuppressive Agents by : Alan C. Sartorelli

Download or read book Antineoplastic and Immunosuppressive Agents written by Alan C. Sartorelli and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 1100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past two decades a number of attempts have been made, with varying degrees of success, to collect in a single treatise available information on the basic and applied pharmacology and biochemical mechanism of action of antineoplastic and immunosuppressive agents. The logarithmic growth of knowledge in this field has made it progressively more difficult to do justice to all aspects of this topic, and it is possible that the present handbook, more than four years in preparation, may be the last attempt to survey in a single volume the entire field of drugs employed in cancer chemotherapy and immunosuppression. Even in the present instance, it has proved necessary for practical reasons to publish the material in two parts, although the plan of the work constitutes, at least in the editors' view, a single integrated treatment of this research area. A number of factors have contributed to the continuous expansion of research in the areas of cancer chemotherapy and immunosuppression. Active compounds have been emerging at ever-increasing rates from experimental tumor screening systems maintained by a variety of private and governmental laboratories through out the world. At the molecular level, knowledge of the modes of action of established agents has continued to expand, and has permitted rational drug design to play a significantly greater role in a process which, in its early years, depended almost completely upon empirical and fortuitous observations.

National Library of Medicine Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 752 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1970 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

International Symposium on L-Asparaginase

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Publisher :
ISBN 13 :
Total Pages : 436 pages
Book Rating : 4.:/5 (311 download)

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Book Synopsis International Symposium on L-Asparaginase by :

Download or read book International Symposium on L-Asparaginase written by and published by . This book was released on 1971 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Chemotherapy Reports

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Publisher :
ISBN 13 :
Total Pages : 1432 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cancer Chemotherapy Reports by :

Download or read book Cancer Chemotherapy Reports written by and published by . This book was released on 1972 with total page 1432 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Chemotherapy 1

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Publisher : Springer Science & Business Media
ISBN 13 : 1461339030
Total Pages : 351 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Cancer Chemotherapy 1 by : Franco M. Muggia

Download or read book Cancer Chemotherapy 1 written by Franco M. Muggia and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Where do you begin to look for a recent, authoritative article on the diagnosis or management ofa particular malignancy? The few general onco logy textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often prelimi nary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can nev er be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by div iding the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Directory of Therapeutic Enzymes

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Publisher : CRC Press
ISBN 13 : 1420038370
Total Pages : 312 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Directory of Therapeutic Enzymes by : Barry M. McGrath

Download or read book Directory of Therapeutic Enzymes written by Barry M. McGrath and published by CRC Press. This book was released on 2005-08-12 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carefully crafted to provide tightly focused and authoritative information, the Directory of Therapeutic Enzymes covers all approved therapeutic enzymes currently used in medicine. Written mainly by industry experts, the book includes information sourced directly from the company that developed or manufactured the product. It explores major

Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 1040 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Current Catalog by : National Library of Medicine (U.S.)

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1970 with total page 1040 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes subject section, name section, and 1968-1970, technical reports.

Oncology, 1970: Experimental cancer therapy

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Publisher :
ISBN 13 :
Total Pages : 576 pages
Book Rating : 4.:/5 (43 download)

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Book Synopsis Oncology, 1970: Experimental cancer therapy by : Randolph Lee Clark

Download or read book Oncology, 1970: Experimental cancer therapy written by Randolph Lee Clark and published by . This book was released on 1971 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Colloques internationaux du Centre national de la recherche scientifique

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Publisher :
ISBN 13 :
Total Pages : 448 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Colloques internationaux du Centre national de la recherche scientifique by : Centre national de la recherche scientifique (France)

Download or read book Colloques internationaux du Centre national de la recherche scientifique written by Centre national de la recherche scientifique (France) and published by . This book was released on 1971 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biomedical Applications of Immobilized Enzymes and Proteins

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Publisher : Springer Science & Business Media
ISBN 13 : 1468426109
Total Pages : 433 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Biomedical Applications of Immobilized Enzymes and Proteins by : Thomas Ming Swi Chang

Download or read book Biomedical Applications of Immobilized Enzymes and Proteins written by Thomas Ming Swi Chang and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: I) ADSORPTION EEEEEEEE E E carrier 2) COVALENT LINKAGE a) Insoluble support b) Intermolecular linkage N'E~ ~~ c) Soluble support 0 \:)....m 3) tM TRIX (MOLECULAR) ENTRAPMENT ~~~~~;;..,J~-polymer matrix 4) ENCAPSULATION membrane FIGURE I. Classification of immobilized enzymes. Covalently linked, adsorbed, and matrix-entrapped enzymes represent stage II, research on the microenvironment. Microencapsulation represents stage III, research on the intracellular environment. Further subdivision of microencapsulated enzymes will be found in Chapter 12. 4 T. M. S. CHANG matrix entrapment. In this section, detailed discussions will center on clinical analysis, urine analysis, monitoring of environmental pollution, radioimmune assay, enzyme-linked immunosorbent assay, enzyme electrodes, and other approaches involving immobilized enzymes, antibodies, and antigens. In the final section, research workers describe and discuss the perspectives of immobilized enzymes and proteins. Here, they speculate on the future potential of possible approaches, even though these may not have been extensively studied or tested at the laboratory stage. The biomedical applications of enzymes and proteins, especially in the thera peutic area, is in a very early stage of development. Much remains to be explored and studied, and the area is wide open for investigators interested in original research in a new interdisciplinary area. References Chang, T. M. S., 1972, Artificial Cells, Charles C. Thomas, Publisher, Springfield, Ill. Dunlop, R. B. (ed.), 1974, Immobilized Biochemicals and Affinity ChrOTIULtography, Plenum Press, N ew York.

Chemotherapy

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Publisher : Springer Science & Business Media
ISBN 13 : 1461566282
Total Pages : 674 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Chemotherapy by : Frederick Becker

Download or read book Chemotherapy written by Frederick Becker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: The promise of chemotherapeutic control in the field of oncology seemed, in the beginning, no less bright than it had proven in the field of bacterial disease, and, therefore, its failures were felt all the more. Despite the serendipitous discoveries and inspired insights which tantalized us with striking remissions, or the rare tumors which proved to be fully susceptible to a given agent, in the main, there has been either total failure or a painfully slow acquisition of an armamentarium against a limited number of malignancies. To expect more, however, was the result of ignorance of the malignant cell, for, as has been described in the previous volumes of this series, the exploitable differences between malignant and normal cells are few or undiscovered. "Differences" is the "numerator" in this formula, but "exploitable" is the operational term, for, although a great number of differences bet\\\een normal and malignant cells have been described, rarely are these differences observed in a vital metabolic pathway or a crucial macromolecu lar structure. Essentially, the basic metabolic pathways and nutritional require ments for :lOrmal and malignant cells are the same, resulting in the fact that no chemotherapeutic agent can successfully inhibit a function in the majority of malignant cells without adversely affecting a similar function in the normal cell. It was, therefore, naive to expect a "magic bullet" which would select the malignant cell and destroy it.

Haematologia

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Publisher :
ISBN 13 :
Total Pages : 536 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Haematologia by :

Download or read book Haematologia written by and published by . This book was released on 1972 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Childhood Acute Lymphoblastic Leukemia

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Publisher : Springer
ISBN 13 : 3319397087
Total Pages : 345 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Childhood Acute Lymphoblastic Leukemia by : Ajay Vora

Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1292 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1974 with total page 1292 pages. Available in PDF, EPUB and Kindle. Book excerpt: