Exercise, Autophagy and Chronic Diseases

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Author :
Publisher : Springer Nature
ISBN 13 : 9811645256
Total Pages : 267 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Exercise, Autophagy and Chronic Diseases by : Ning Chen

Download or read book Exercise, Autophagy and Chronic Diseases written by Ning Chen and published by Springer Nature. This book was released on 2021-09-30 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book establishes a bridge between exercise-mediated functional status of autophagy and non-communicable chronic diseases for elucidating and clarifying the corresponding signal pathways and underlying mechanisms. The book consists of 13 chapters focusing on the in-depth discussion on signal pathways for regulating the functional status of autophagy for the prevention, treatment and rehabilitation of chronic diseases, the optimization of exercise intervention strategies for common and frequently-occurring chronic diseases, and the development of exercise mimetic pills for the persons with disability for exercise performance, or the persons without willing to exercise. This book is interesting and will be useful to a wide readership in the various fields of exercise science, exercise fitness, sports medicine, preventive medicine, and functional foods.

Intermittent Fasting and Autophagy

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Publisher :
ISBN 13 : 9781699883686
Total Pages : 115 pages
Book Rating : 4.8/5 (836 download)

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Book Synopsis Intermittent Fasting and Autophagy by : Adelle Montignac

Download or read book Intermittent Fasting and Autophagy written by Adelle Montignac and published by . This book was released on 2019-10-14 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: Are you tired of dieting and not losing weight quickly enough? If you want to finally lose weight effectively discovering the powerful natural weight loss process of autophagy, then keep reading... Fasting is a technique that has been used by ancient civilizations for clarity, discipline and a method for connecting to a higher power, what they didn't know is how effective fasting was at unlocking a powerful natural mechanism within. Recent scientific research on the inner workings of the body has revealed a regenerative process called autophagy, which is the closest thing to the fountain of youth that we have ever discovered. Autophagy is the body's housekeeping method and is used to clean up and recycle old and damaged cells so that newer and younger cells can be generated. This process may seem complex, but through this book, you will find a summary of how autophagy works and how you can follow some simple lifestyle choices to unlock and accelerate autophagy for its weight loss and anti-aging properties and enjoy the benefits of combating chronic diseases like diabetes, Alzheimer's and cancer. Part of a healthy lifestyle and the weight-loss equation is exercise; it is a well-known fact that 30 minutes of moderate exercise every day has lasting benefits for overall health and will accelerate your weight loss goals. In this book, you will find a summary of the most effective exercises you can do anywhere without the need for equipment. Calisthenics, HIIT, and plyometric exercises are simple movements with significant impact and can be incorporated into your busy life with as little as 10 minutes at a time. Any new habits can be challenging to add to your life, so in this book, you will find the secret 3 step process to giving your healthy new habits real staying power. You'll also receive tips and tricks for an enjoyable fast, effective workout and a path to enhanced wellbeing for long healthy life. The key benefits of this book include: Simplified scientific information in a relatable and enjoyable read Detailed descriptions of highly effective bodyweight exercises A comprehensive list of whole foods to inspire healthy recipes Calorie calculations to determine how much food you really need to lose weight The 3-step process for making new habits stick Tips and tricks for an enjoyable fast and weight loss journey There is a lot of information out there about dieting and weight loss, in this book you will understand how to tap into the natural processes within your body, how to stop 'dieting' and start living. Fasting and autophagy are not a diet trend to try and discard, and it's not about starving yourself in agony. It is a lifestyle that can lead to a healthy relationship with food, fight symptoms of aging, and help you combat chronic illnesses. Would You like to Know More? "Scroll to the top of the page and click the BUY NOW button"

Autophagy in Health and Disease

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Author :
Publisher : Academic Press
ISBN 13 : 0128220228
Total Pages : 446 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Autophagy in Health and Disease by :

Download or read book Autophagy in Health and Disease written by and published by Academic Press. This book was released on 2020-06-30 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy in Health and Disease, Volume 175, presents the latest insights from renowned experts in the field who discuss the key role of autophagic responses in the preservation of cellular and organismal homeostasis and how defects in the molecular apparatus for autophagy drive or accompany disease. Specific chapters in this new release include Crosstalk between autophagy and cell death signaling: mechanisms and therapeutic relevance, C. elegans to model autophagy-related human disorders, Autophagy in Kidney Disease: advances and therapeutic potential, Autophagy in Chronic Lung Disease, Autophagy in motoneuronal disorders, Strategies employed by viruses to manipulate autophagy, and much more. Provides an outstanding panel of recognized experts in the field who discuss the latest in autophagy Includes critical discussions of autophagy in the context of each major human disorder Models autophagy-related human pathologies in lower eukaryotes

Jump Start Autophagy

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Author :
Publisher : Simon and Schuster
ISBN 13 : 161243956X
Total Pages : 95 pages
Book Rating : 4.6/5 (124 download)

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Book Synopsis Jump Start Autophagy by : Melissa Mayer

Download or read book Jump Start Autophagy written by Melissa Mayer and published by Simon and Schuster. This book was released on 2019-10-22 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Harness your body’s natural cell-rejuvenating process for amazing health benefits To maintain good health, it is vital that your body’s natural detoxing process of cleaning out damaged cells and regenerating new ones, known as autophagy, is working well. Dysfunctional cellular processes can cause all kinds of serious issues, from premature aging to cancer. On the other hand, a healthy autophagy process can reduce inflammation, prevent skin issues, boost metabolism, and even heal autoimmune issues. Jump Start Autophagy will give you all the tools you need to hack your cells for a longer, healthier life. The book will walk you through the science of autophagy, how it works, and why our bodies need it. It will break down the different ways our bodies are signaled to kick start autophagy; and, best of all, show you concrete examples, activities, and methods to push your own body into autophagy to achieve healthier skin, boost your metabolism, heal inflammation, and so much more.

The Role of Autophagy in Cardiac Aging and Aging-associated Chronic Diseases

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Author :
Publisher :
ISBN 13 : 9781658420815
Total Pages : 143 pages
Book Rating : 4.4/5 (28 download)

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Book Synopsis The Role of Autophagy in Cardiac Aging and Aging-associated Chronic Diseases by : Shuyi Wang

Download or read book The Role of Autophagy in Cardiac Aging and Aging-associated Chronic Diseases written by Shuyi Wang and published by . This book was released on 2019 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is becoming an escalating issue in the world as human life expectancy continues to rise. Advanced aging imposes a cadre of chronic disease including cardiovascular diseases. The aging heart displays unfavorable changes in both geometry and function including increased left ventricular (LV) mass, reduced cardiac reserve capacity, myocardial fibrosis and increased risk of arrhythmia, contributing to poor exercise capacitance (effort intolerance) and frailty in the elderly. In addition, aging also increases the risk of many chronic diseases that jeopardize the cardiovascular function and quality of life in the elderly. With progressive aging, several pathological conditions including obesity, type II diabetes mellitus, Alzheimer’s disease and cancer are on the horizon. For example, obesity has been considered as a trigger for premature aging, leading to pathological cardiac remodeling and compromised ventricular function. Alzheimer’s disease is a neurodegenerative disease featured by accumulation of amyloid plaque and neurofibrillary tangles. Alzheimer’s disease may provoke cardiovascular dysfunction impairment of diastolic function. Over the past decades intense effort has been made towards understanding the mechanistic framework behind aging, obesity and Alzheimer’s disease in the pathogenesis of cardiovascular anomalies. An emerging role of dysregulated autophagy, a conservative homeostatic process for cellular quality control by way of disposal and recycling of cellular components, has surfaced in cardiac anomalies under all these pathological settings. To this end, this dissertation research will focus on the underlying mechanism of cardiac remodeling and contractile dysfunction during the normal aging process, as well as aging-associated conditions such as obesity and Alzheimer’s disease. The major findings from my work revealed that (1): Ablation of TLR4 restores autophagy level through the regulation of NCoR1/HDAC and improves heart function in aging; (2): Knocking out of Akt and AMPK facilitates premature cardiac aging in a joint manner; (3): Mitochondrial aldehyde dehydrogenase (ALDH2) overexpression protects obese heart through SUV39H1-Sirt1 signaling; and (4): Melatonin protects Alzheimer’s disease-associated heart dysfunction through cGAS-STING regulated autophagy in the presence of ALDH2.

Functional Foods for Chronic Diseases (Volume 3)

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Author :
Publisher : D&A Inc.
ISBN 13 : 9780976753544
Total Pages : 280 pages
Book Rating : 4.7/5 (535 download)

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Book Synopsis Functional Foods for Chronic Diseases (Volume 3) by : Danik M. Martirosyan

Download or read book Functional Foods for Chronic Diseases (Volume 3) written by Danik M. Martirosyan and published by D&A Inc.. This book was released on 2008-02-10 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of this book serves two great purposes. First, it spreads the word about new functional food products for chronic diseases such as hypertension, diabetes, and obesity to the general public. It not only introduces new functional foods, but also shows the investigations and research that led to their creation. Second, the book preserves the numerous ideas and contributions made in the field. This shows the progress and evolution of this thriving field, with the power to change the lives of millions of people. The forever growing field of functional foods brings together research scientists, food manufacturers and consumers who are committed to this issue through modern achievements of surgical approaches and potential of drug therapy, where particular emphasis is placed on the unresolved problems of pharmaceutical side effects.

Molecular and Cellular Regulation of Adaptation to Exercise

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Publisher : Academic Press
ISBN 13 : 0128039922
Total Pages : 588 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Molecular and Cellular Regulation of Adaptation to Exercise by : Claude Bouchard

Download or read book Molecular and Cellular Regulation of Adaptation to Exercise written by Claude Bouchard and published by Academic Press. This book was released on 2015-11-16 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Aspects of Exercise Biology and Exercise Genomics, the latest volume in the Progress in Molecular Biology and Translational Science series includes a comprehensive summary of the evidence accumulated thus far on the molecular and cellular regulation of the various adaptations taking place in response to exercise. Changes in the cellular machinery are described for multiple tissues and organs in terms of signaling pathways, gene expression, and protein abundance. Adaptations to acute exercise as well as exposure to regular exercise are also discussed and considered. Includes a comprehensive summary of the evidence accumulated thus far on the molecular and cellular regulation of the various adaptations taking place in response to exercise Contains contributions from leading authorities Informs and updates on all the latest developments in the field of exercise biology and exercise genomics

The Switch

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Publisher : Simon and Schuster
ISBN 13 : 1982115416
Total Pages : 320 pages
Book Rating : 4.9/5 (821 download)

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Book Synopsis The Switch by : James W. Clement

Download or read book The Switch written by James W. Clement and published by Simon and Schuster. This book was released on 2019-12-31 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: How can you lose weight, ease chronic conditions, and stay healthier longer? Discover how to “rewrite your health destiny” (David Perlmutter, MD, #1 New York Times bestselling author of Grain Brain) with this accessible book that teaches you how to flip the switch on your metabolism with intermittent fasting, protein cycling, and keto. Within each of us is an ancient mechanism that eliminates toxic materials, initiates fat burning, and protects cells from becoming dysfunctional—or turning cancerous. It’s called autophagy, and when it’s turned on, the complex operation not only can slow down the aging process, it can optimize biological function as a whole, helping to stave off all manner of diseases and affording us the healthy life spans we never thought possible. It’s the body’s ultimate switch to life. So how can we positively activate this switch? How frequently should we fast and for how long? Which foods dial up autophagy or, conversely, turn it down? How much exercise and what types are recommended? What’s the sweet spot between intermittent fasting, protein cycling, and ketogenic eating? Backed by a wealth of scientific data and featuring a gallery of guidelines to follow for lasting results, “The Switch offers a paradigm shift in the way we think about health—and how to avoid decline and illness. This is a must read” (Mark Hyman, #1 New York Times bestselling author).

Mitochondrial Dysfunction

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Publisher : Elsevier
ISBN 13 : 1483218619
Total Pages : 527 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Mitochondrial Dysfunction by : Lawrence H. Lash

Download or read book Mitochondrial Dysfunction written by Lawrence H. Lash and published by Elsevier. This book was released on 2013-10-22 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.

Reversibility of Chronic Disease and Hypersensitivity, Volume 5

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Author :
Publisher : CRC Press
ISBN 13 : 1498781373
Total Pages : 902 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Reversibility of Chronic Disease and Hypersensitivity, Volume 5 by : William J. Rea

Download or read book Reversibility of Chronic Disease and Hypersensitivity, Volume 5 written by William J. Rea and published by CRC Press. This book was released on 2017-12-14 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt: The clinical approaches to the chronic degenerative diseases that drain our resources, and compromise our well-being, have become almost exclusively symptom-focused. The common wisdom is that they are idiopathic with final outcomes to be managed rather than prevented or cured. That they are potentially reversible rarely enters any discussion between doctor and patient. Reversibility of Chronic Disease and Hypersensitivity, Volume 5: Treatment Options of Chemical Sensitivity, the final volume of this set, offers a much different perspective on chronic degenerative disease; one that disputes the idiopathic label attached to most, as well as the usual fatalistic prognosis.

Frailty and Sarcopenia

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535134833
Total Pages : 256 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Frailty and Sarcopenia by : Yannis Dionyssiotis

Download or read book Frailty and Sarcopenia written by Yannis Dionyssiotis and published by BoD – Books on Demand. This book was released on 2017-08-30 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frailty is considered a multisystem impairment that makes an individual vulnerable to external or internal stressors. Sarcopenia, the age-dependent loss of muscle mass and function, is proposed as the biological substrate and the pathway whereby the consequences of physical frailty develop. These syndromes are associated with a negative impact in quality of life and can lead to the occurrence of disability, institutionalization, and even mortality. The book focuses upon all the related aspects of frailty and sarcopenia and the new advancements in the related treatments including complex issues and research. It includes high-quality chapters in all related aspects for the syndromes of sarcopenia and frailty, which adversely affect the function and overall effectiveness of the musculoskeletal system and interventions to promote rehabilitation.

Metabolic Cardiomyopathy

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Publisher : CRC Press
ISBN 13 : 9783887631048
Total Pages : 188 pages
Book Rating : 4.6/5 (31 download)

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Book Synopsis Metabolic Cardiomyopathy by : H. Böhles

Download or read book Metabolic Cardiomyopathy written by H. Böhles and published by CRC Press. This book was released on 2004 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.

Autophagy: Biology and Diseases

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Author :
Publisher : Springer Nature
ISBN 13 : 9811542724
Total Pages : 734 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Autophagy: Biology and Diseases by : Weidong Le

Download or read book Autophagy: Biology and Diseases written by Weidong Le and published by Springer Nature. This book was released on 2020-07-15 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book consists of 3 volumes: Basic Science (Volume 1), Clinical Science (Volume 2) and Technology and Methodology (Volume 3). Volume 2 focuses on the clinical aspects of autophagy research, discussing the role of autophagy in neuropsychiatric disorders, the cardiovascular, immune, digestive and endocrine systems, as well as tumors, infection, the kidney, and the respiratory and hematological systems. It also addresses autophagy-related drug development. Written and edited by a team of 90 experts, and presenting the state of the art in autophagy research, this book is a valuable reference resource for researchers and clinicians alike. It can also be used as supplementary material for graduate students majoring in biology and medicine

Built from Broken

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Author :
Publisher : Saltwrap
ISBN 13 : 9781735728506
Total Pages : 348 pages
Book Rating : 4.7/5 (285 download)

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Book Synopsis Built from Broken by : Scott H Hogan

Download or read book Built from Broken written by Scott H Hogan and published by Saltwrap. This book was released on 2021-07 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Built from Broken is a complete, research-backed corrective exercise guide to healing painful joints and building a resilient body. Most middle-aged fitness enthusiasts and athletes have been dragged down by joint pain, injuries, and all the other ailments that are commonly accepted as "part of getting older." This book systematically dissects the common causes of joint pain, explaining the latest science of tendinopathy and pain management, and provides a complete road map for conquering joint pain, improving movement and posture, and building a strong, functional body that stands the test of time.

Sarcopenia

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119597900
Total Pages : 464 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Sarcopenia by : Alfonso J. Cruz-Jentoft

Download or read book Sarcopenia written by Alfonso J. Cruz-Jentoft and published by John Wiley & Sons. This book was released on 2021-06-15 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: SARCOPENIA An in-depth examination of sarcopenia’s underexplored yet widespread impact within the field of gerontology Sarcopenia is common in older men and women, and yet awareness of its clinical relevance is still relatively low. Only formally included in the International Classification of Diseases in 2016, the condition may impact societies with serious health-related and financial consequences unless consistent, effective methods of identification and management are adopted. This second edition of Sarcopenia provides geriatricians and other healthcare professionals with a revised and expanded examination of this understudied and underdiagnosed condition. Edited by two leading authorities on the subject, it covers the epidemiology and diagnosis of sarcopenia, as well as treatment options and possible prevention strategies. Eight newly written chapters build upon existing knowledge with fresh data on topics including sarcopenia’s biomarkers and its impact on the healthcare economy. This important text: Defines sarcopenia and explains its clinical relevance Covers all recent scientific evidence Outlines treatment options Considers prevention strategies Discusses sarcopenia as a public health priority Features eight new chapters covering topics such as sarcopenia’s clinical management, its biomarkers, and its financial impact Containing vital information for clinicians and other professionals working in geriatric care, nursing homes, nutrition, cancer, endocrinology, surgery, sports medicine and many other specialties, Sarcopenia, second edition, is a groundbreaking and essential new resource.

Anti-aging Drugs

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 178262435X
Total Pages : 592 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Anti-aging Drugs by : Alexander M Vaiserman

Download or read book Anti-aging Drugs written by Alexander M Vaiserman and published by Royal Society of Chemistry. This book was released on 2017-02-01 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points prior to human studies. This book provides an overview of current research aimed to search for life-extending medications and describes pharmacological aspects of anti-aging medicine. Readers are introduced to the fascinating historical background of geroprotection in the first chapter. In-depth information on models for investigating geroprotective drugs precedes a section covering anti-aging properties of pharmaceutical compounds, such as calorie restriction mimetics, autophagy inducers, senolytics and mitochondrial antioxidants. Finally, strategies to translate discoveries from aging research into drugs and healthcare policy perspectives on anti-ageing medicine are provided to give a complete picture of the field. A timely and carefully edited collection of chapters by leading researchers in the field, this book will be a fascinating and useful resource for pharmacologists, gerontologists and any scientifically interested person wishing to know more about the current status of research into anti-aging remedies, challenges and opportunities.

Cell Death

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Publisher : BoD – Books on Demand
ISBN 13 : 9535122363
Total Pages : 448 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Cell Death by : Tobias Ntuli

Download or read book Cell Death written by Tobias Ntuli and published by BoD – Books on Demand. This book was released on 2015-12-16 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of selected and relevant research, concerning the developments within the Cell Death field of study. Each contribution comes as a separate chapter complete in itself but directly related to the books topics and objectives. The target audience comprises scholars and specialists in the field.