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Evolutionary Genomics Of Divergence And Adaptation Within The Model Fungi Neurospora Crassa And Neurospora Tetrasperma
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Book Synopsis Evolutionary Genomics of Divergence and Adaptation Within the Model Fungi Neurospora Crassa and Neurospora Tetrasperma by : Christopher Ellison
Download or read book Evolutionary Genomics of Divergence and Adaptation Within the Model Fungi Neurospora Crassa and Neurospora Tetrasperma written by Christopher Ellison and published by . This book was released on 2011 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: The work presented in this dissertation involves the interpretation of patterns of DNA and gene expression variation to infer ways in which evolutionary events and processes have shaped the life histories of species of filamentous fungi within the genus Neurospora. The first chapter involves a comparison between genome sequences from both mating types of the self-fertile fungus Neurospora tetrasperma. Self-fertility in this species is associated with a large, sex-linked region of suppressed recombination. The structural rearrangements involved in the suppression of recombination are identified here for the first time and a model for the evolution of this non-recombining chromosomal region is developed. Additionally, evidence is presented that suggests the mat a-linked region of suppressed recombination is accumulating deleterious alleles at a faster rate than the mat A-linked region and thus may be in the early stages of degeneration. Discovering the genetic basis behind adaptive phenotypes has long been considered the holy grail of evolutionary genetics, yet most instances where adaptive alleles have been identified involved targeting candidate genes based on their having a function related to an obvious phenotype such as pigmentation. This forward-ecology approach is difficult for most fungi because they lack obvious phenotypes. In the second chapter of this dissertation, a reverse-ecology approach is utilized to identify candidate genes involved in local adaptation to cold temperature in two recently diverged populations of Neurospora crassa. High-resolution genome scans between populations were performed to identify genomic islands of extreme divergence. Two such islands were identified and found to contain genes whose functions, pattern of nucleotide polymorphism, and null phenotype are consistent with local adaptation. The third chapter extends the DNA-based analyses presented in the second chapter to explore natural variation in gene expression within and between these same N. crassa populations. Intrapopulation variation in gene expression is harnessed to identify regulatory modules and to provide a tool for inferring functional information for unannotated genes. Divergence in regulatory networks between populations is assessed, providing insight into potential functional differences between these populations.
Book Synopsis Neurospora by : Durgadas Prabhakar Kasbekar
Download or read book Neurospora written by Durgadas Prabhakar Kasbekar and published by Caister Academic Press Limited. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building on over 70 years of genetics research, Neurospora continues to be the leading model for the study of the genomics and molecular biology of filamentous fungi. The ease of culture, amenability to genetic and molecular genetic analysis, and the close correlation between genetic and biochemical traits are some of its advantages. Research with Neurospora has provided insights unachievable from work with simpler systems and difficult to extract from more complicated ones, cementing its position as a leading model system. In recent years the application of modern high throughput analyses had led to a deluge of information on the genomics and molecular biology of Neurospora. This timely book aims to distil the most important findings to provide a snapshot of the current research landscape. In this book, internationally recognised Neurospora experts critically review the most important research and demonstrate the breadth of applications to industrial biology, biofuels, agriculture, and human health. The opening chapter is an introduction to the organism. Following chapters cover topics such as: carotenoid biosynthesis, polysaccharide deconstruction, genome biology, genome recombination, gene regulation, signal transduction, self-recognition, development, circadian rhythms and mutation. The book closes with a fascinating look at the history and future trends for research on Neurospora gene and genome analysis. This volume is essential for everyone working with Neurospora and other filamentous fungi. A recommended book for all biology, agriculture and medical libraries.
Book Synopsis Statistical Population Genomics by : Julien Y Dutheil
Download or read book Statistical Population Genomics written by Julien Y Dutheil and published by . This book was released on 2020-10-08 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demography inference, population structure analysis and detection of selection, using both model-based inference and simulation procedures. Last but not least, it offers an overview of the current knowledge acquired by applying such methods to a large variety of eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, pointers to the relevant literature, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Statistical Population Genomics aims to promote and ensure successful applications of population genomic methods to an increasing number of model systems and biological questions. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Download or read book Clonality written by John Avise and published by Oxford University Press. This book was released on 2008-10-23 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approximately 99.9% of vertebrate species reproduce sexually. The exceptional 0.1% reproduce via asexual or clonal means, which vary wildly and are fascinating in their own right. In this book, John C. Avise describes the genetics, ecology, natural history, and evolution of the world's approximately 100 species of vertebrate animal that routinely display one form or another of clonal or quasi-clonal reproduction. By considering the many facets of sexual abstinence and clonal reproduction in vertebrate animals, Avise sheds new light on the biological meaning and ramifications of standard sexuality.
Book Synopsis Genetic Transformation Systems in Fungi, Volume 2 by : Marco A. van den Berg
Download or read book Genetic Transformation Systems in Fungi, Volume 2 written by Marco A. van den Berg and published by Springer. This book was released on 2014-10-31 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi are an economic very important class of microbes. Not only do they host a range of versatile enzymes used in industrial applications (biofuels, laundry, food processing), as well do they produce several very important pharmaceutical drugs (statins and penicillins). Moreover, fungal pathogens can cause great damage in agricultural production (Phytophthora and Botrytis) and during mammalian infections (Penicillium marneffei and Candida). Transformation of DNA is used to understand the genetic basis behind these traits. Several different techniques have been developed over the years and readily shown to be decisive methods to improve fungal biotechnology. This book will cover the basics behind the most commonly used transformation methods, as well as associated tools and techniques. Each chapter will provide protocols along with examples to be used in laboratories worldwide.
Book Synopsis The Fungal Kingdom by : Joseph Heitman
Download or read book The Fungal Kingdom written by Joseph Heitman and published by John Wiley & Sons. This book was released on 2020-07-10 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi research and knowledge grew rapidly following recent advances in genetics and genomics. This book synthesizes new knowledge with existing information to stimulate new scientific questions and propel fungal scientists on to the next stages of research. This book is a comprehensive guide on fungi, environmental sensing, genetics, genomics, interactions with microbes, plants, insects, and humans, technological applications, and natural product development.
Book Synopsis An Introduction to Ecological Genomics by : Nico M. van Straalen
Download or read book An Introduction to Ecological Genomics written by Nico M. van Straalen and published by Oxford University Press. This book was released on 2012 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors also provide a comparative survey of the properties of genomes (genome size, gene families, synteny, and polymorphism) for prokaryotes as well as the main eukaryotic models.
Book Synopsis Evolution of Fungi and Fungal-Like Organisms by : Stefanie Pöggeler
Download or read book Evolution of Fungi and Fungal-Like Organisms written by Stefanie Pöggeler and published by Springer Science & Business Media. This book was released on 2011-07-07 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on sequence analyses of many different genes, the past decade has provided us with a profound knowledge of fungal systematics and phylogeny. In addition, a number of sequences of complete fungal genomes have been identified and several others will soon follow. In this volume, leading experts address questions concerning the origin of the fungal kingdom and fungal evolution at a level of analytical refinement that has never been possible before. The following major aspects are highlighted: evolutionary roots of fungi; evolution of signaling in fungi and fungal-like organisms; evolution of mutualistic systems and metabolism in fungi; and evolutionary mechanisms and trends.
Book Synopsis Fungal Plant Pathogens, 2nd Edition by : Charles R. Lane
Download or read book Fungal Plant Pathogens, 2nd Edition written by Charles R. Lane and published by CABI. This book was released on 2023-07-30 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This substantially updated edition now in full colour provides key techniques used when working with fungal and fungal-like plant pathogens. As a practical manual it also deals with disease recognition, detection and identification of fungi, plus methods to characterise and curate fungi and handle them under quarantine and quality assurance systems. Fungal Plant Pathogens: Applied Techniques, 2nd edition provides a valuable guide to investigating fungal plant diseases and interpreting laboratory findings for postgraduate and advanced undergraduate students, extension plant pathologists, consultants and advisers in agriculture, forestry and horticulture, and the food supply chain.
Book Synopsis The Fusarium Laboratory Manual by : John F. Leslie
Download or read book The Fusarium Laboratory Manual written by John F. Leslie and published by John Wiley & Sons. This book was released on 2008-02-28 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the first time in over 20 years, a comprehensive collection of photographs and descriptions of species in the fungal genus Fusarium is available. This laboratory manual provides an overview of the biology of Fusarium and the techniques involved in the isolation, identification and characterization of individual species and the populations in which they occur. It is the first time that genetic, morphological and molecular approaches have been incorporated into a volume devoted to Fusarium identification. The authors include descriptions of species, both new and old, and provide protocols for genetic, morphological and molecular identification techniques. The Fusarium Laboratory Manual also includes some of the evolutionary biology and population genetics thinking that has begun to inform the understanding of agriculturally important fungal pathogens. In addition to practical “how-to” protocols it also provides guidance in formulating questions and obtaining answers about this very important group of fungi. The need for as many different techniques as possible to be used in the identification and characterization process has never been greater. These approaches have applications to fungi other than those in the genus Fusarium. This volume presents an introduction to the genus Fusarium, the toxins these fungi produce and the diseases they can cause. "The Fusarium Laboratory Manual is a milestone in the study of the genus Fusarium and will help bridge the gap between morphological and phylogenetic taxonomy. It will be used by everybody dealing with Fusarium in the Third Millenium." --W.F.O. Marasas, Medical Research Council, South Africa
Book Synopsis Introduction to Fungi by : John Webster
Download or read book Introduction to Fungi written by John Webster and published by Cambridge University Press. This book was released on 1980-06-19 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This new edition of the universally acclaimed and widely used textbook on fungal biology has been completely rewritten, drawing directly on the authors' research and teaching experience. The text takes account of the rapid and exciting progress that has been made in the taxonomy, cell and molecular biology, biochemistry, pathology and ecology of the fungi. Features of taxonomic significance are integrated with natural functions, including their relevance to human affairs."--BOOK JACKET.
Download or read book Genes in Conflict written by Austin BURT and published by Harvard University Press. This book was released on 2009-06-30 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering all species from yeast to humans, this is the first book to tell the story of selfish genetic elements that act narrowly to advance their own replication at the expense of the larger organism.
Book Synopsis Recent Developments on Genus Chaetomium by : Ahmed M. Abdel-Azeem
Download or read book Recent Developments on Genus Chaetomium written by Ahmed M. Abdel-Azeem and published by Springer Nature. This book was released on 2019-12-27 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chaetomium genus was established by Gustav Kunze in 1817. According to Index Fungorum Partnership, there are 273 Chaetomium species accepted till now. Members of the genus Chaetomium are capable of colonizing various substrates and are well-known for their ability to degrade cellulose and to produce a variety of bioactive metabolites. More than 200 compounds have been reported from this genus. A huge number of new and bioactive secondary metabolites associated with unique and diverse structural types, such as chaetoglobosins, epipolythiodioxopiperazines, azaphilones, depsidones, xanthones, anthraquinones, chromones, and steroids, have been isolated and identified. Many of the compounds have been reported to possess significant biological activities, such as antitumor, antimalarial, cytotoxic, enzyme inhibitory, antimicrobial, phytotoxic, antirheumatoid and other activities. Chaetomium taxa are frequently reported to be cellulase and ligninase producers with the ability to degrade cellulosic and woody materials. This is the first, comprehensive volume covering Chaetomium genus in detail. It includes the latest research, methods, and applications, and was written by scholars working directly in the field. The book also contains informative illustrations and is fully referenced for further reading.
Book Synopsis Structure and Dynamics of Fungal Populations by : J. Worrall
Download or read book Structure and Dynamics of Fungal Populations written by J. Worrall and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi are among the most versatile and diverse groups of organisms in their morphology, life cycles, and ecology. This has provided endless fasci nation and intrigue to those who have studied fungi, but it has also made it difficult to understand fungal biology from the perspective of the broader fields of evolution, ecology, genetics, and population biology. That is changing. Details of fungal biology have been elucidated at an exciting pace, increasingly allowing us to understand fungi on the bases of general biological principles. Moreover, many who study fungi have lately emulated some of the great mycologists and plant pathologists of the early years in applying an insight born of broad perspective. This change has been particularly apparent in fungal population biology. In this book, many of those at the forefront of that change summarize, integrate and comment on recent developments and ideas on populations of fungi. By taking a broad perspective, they show how new information on fungi may contribute to concepts and ideas of biology as a whole. Just as important, they contribute to further invigoration of fungal population research by illuminating mycology with new ideas and concepts, derived in part from other biological fields.
Book Synopsis Protein Bioinformatics by : Cathy H. Wu
Download or read book Protein Bioinformatics written by Cathy H. Wu and published by Humana. This book was released on 2017-02-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume introduces bioinformatics research methods for proteins, with special focus on protein post-translational modifications (PTMs) and networks. This book is organized into four parts and covers the basic framework and major resources for analysis of protein sequence, structure, and function; approaches and resources for analysis of protein PTMs, protein-protein interactions (PPIs) and protein networks, including tools for PPI prediction and approaches for the construction of PPI and PTM networks; and bioinformatics approaches in proteomics, including computational methods for mass spectrometry-based proteomics and integrative analysis for alternative splice isoforms, for functional discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory or computational protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Protein Bioinformatics: From Protein Modifications and Networks to Proteomics is a valuable resource for readers who wish to learn about state-of-the-art bioinformatics databases and tools, novel computational methods, and future trends in protein and proteomic data analysis in systems biology. This book is useful to researchers who work in the biotechnology and pharmaceutical industries, and in various academic departments, such as biological and medical sciences and computer sciences and engineering.
Book Synopsis Mycology and Microbiology (A Textbook for UG and PG Courses) by : C. Manoharachary
Download or read book Mycology and Microbiology (A Textbook for UG and PG Courses) written by C. Manoharachary and published by Scientific Publishers. This book was released on 2016-05-01 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi and microbes have predominant influence in our lives. They are directly or indirectly involved in generating the food we eat and drink, besides providing life saving pharmaceutical products, including the sources of enzymes. They play a vital role in recycling of organic matter and several ecological processes. Both fungi and microbes have contributed several billion dollars worth of technological products. For instance: yeast is used in brewing and bakery, Lactobacillus ferments milk to yoghurt and a number of edible mushrooms are rich in nutrients besides possessing many medicinal properties. Bacteria and fungi serve as key organisms in understanding life processes, genetic engineering and as experimental organisms. Therefore, it is necessary to study the biology and biotechnology of these organisms. It is a humble attempt of the authors to make the readers understand the biology and biotechnology of fungi and microbes in a simpler way and also to communicate the recent developments.
Book Synopsis Modern Tools and Techniques to Understand Microbes by : Ajit Varma
Download or read book Modern Tools and Techniques to Understand Microbes written by Ajit Varma and published by Springer. This book was released on 2017-04-21 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides essential molecular techniques and protocols for analyzing microbes that are useful for developing novel bio-chemicals, such as medicines, biofuels, and plant protection substances. The topics and techniques covered include: microbial diversity and composition; microorganisms in the food industry; mass cultivation of sebacinales; host-microbe interaction; targeted gene disruption; function-based metagenomics to reveal the rhizosphere microbiome; mycotoxin biosynthetic pathways; legume-rhizobium symbioses; multidrug transporters of yeast; drug-resistant bacteria; the fungal endophyte piriformospora indica; medicinal plants; arbuscular mycorrhizal fungi; biosurfactants in microbial enhanced oil recovery; and biocontrol of the soybean cyst nematode with root endophytic fungi; as well as microbe-mediated drought tolerance in plants.
